Multiscale Biomechanical Modeling of the Brain Book

Multiscale Biomechanical Modeling of the Brain


  • Author : Mark F. Horstemeyer
  • Publisher : Elsevier
  • Release Date : 2021-11-02
  • Genre: Technology & Engineering
  • Pages : 276
  • ISBN 10 : 9780128181447

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Multiscale Biomechanical Modeling of the Brain Excerpt :

Multiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection. The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. Presents concepts in a theoretical and thermodynamic framework for each length scale Teaches readers not only how to use an existing multiscale model for each brain but also how to develop a new multiscale model Takes an integrated experimental-computational approach and gives structured multiscale coverage of the problems

Multiscale Biomechanical Modeling of the Brain Book

Multiscale Biomechanical Modeling of the Brain


  • Author : Mark F. Horstemeyer
  • Publisher : Academic Press
  • Release Date : 2021-10-27
  • Genre: Technology & Engineering
  • Pages : 276
  • ISBN 10 : 9780128181454

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Multiscale Biomechanical Modeling of the Brain Excerpt :

Multiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection. The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. Presents concepts in a theoretical and thermodynamic framework for each length scale Teaches readers not only how to use an existing multiscale model for each brain but also how to develop a new multiscale model Takes an integrated experimental-computational approach and gives structured multiscale coverage of the problems

Multiscale Modeling in Biomechanics and Mechanobiology Book

Multiscale Modeling in Biomechanics and Mechanobiology


  • Author : Suvranu De
  • Publisher : Springer
  • Release Date : 2014-10-10
  • Genre: Technology & Engineering
  • Pages : 286
  • ISBN 10 : 9781447165996

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Multiscale Modeling in Biomechanics and Mechanobiology Excerpt :

Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Multiscale Multimodal Medical Imaging Book

Multiscale Multimodal Medical Imaging


  • Author : Xiang Li (Computer scientist)
  • Publisher : Springer Nature
  • Release Date : 2022
  • Genre: Diagnostic imaging
  • Pages : 139
  • ISBN 10 : 9783031188145

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Multiscale Multimodal Medical Imaging Excerpt :

This book constitutes the refereed proceedings of the Third International Workshop on Multiscale Multimodal Medical Imaging, MMMI 2022, held in conjunction with MICCAI 2022 in singapore, in September 2022. The 12 papers presented were carefully reviewed and selected from 18 submissions. The MMMI workshop aims to advance the state of the art in multi-scale multi-modal medical imaging, including algorithm development, implementation of methodology, and experimental studies. The papers focus on medical image analysis and machine learning, especially on machine learning methods for data fusion and multi-score learning.

Mathematical Modelling and Biomechanics of the Brain Book

Mathematical Modelling and Biomechanics of the Brain


  • Author : Corina Drapaca
  • Publisher : Springer Nature
  • Release Date : 2019-09-06
  • Genre: Mathematics
  • Pages : 155
  • ISBN 10 : 9781493998104

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Mathematical Modelling and Biomechanics of the Brain Excerpt :

This monograph aims to provide a rigorous yet accessible presentation of some fundamental concepts used in modeling brain mechanics and give a glimpse of the insights and advances that have arisen as a result of the nascent interaction of the mathematical and neurosurgical sciences. It begins with some historical perspective and a brief synopsis of the biomedical/biological manifestations of the clinical conditions/diseases considered. Each chapter proceeds with a discussion of the various mathematical models of the problems considered, starting with the simplest models and proceeding to more complex models where necessary. A detailed list of relevant references is provided at the end of each chapter. With the beginning research student in mind, the chapters have been crafted to be as self-contained as possible while addressing different clinical conditions and diseases. The book is intended as a brief introduction to both theoreticians and experimentalists interested in brain mechanics, with directions and guidance for further reading, for those who wish to pursue particular topics in greater depth. It can also be used as a complementary textbook in a graduate level course for neuroscientists and neuroengineers.

Practical Aspects of Computational Chemistry Book

Practical Aspects of Computational Chemistry


  • Author : Jerzy Leszczynski
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-10-03
  • Genre: Science
  • Pages : 465
  • ISBN 10 : 9789048126873

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Practical Aspects of Computational Chemistry Excerpt :

"Practical Aspects of Computational Chemistry" presents contributions on a range of aspects of Computational Chemistry applied to a variety of research fields. The chapters focus on recent theoretical developments which have been used to investigate structures and properties of large systems with minimal computational resources. Studies include those in the gas phase, various solvents, various aspects of computational multiscale modeling, Monte Carlo simulations, chirality, the multiple minima problem for protein folding, the nature of binding in different species and dihydrogen bonds, carbon nanotubes and hydrogen storage, adsorption and decomposition of organophosphorus compounds, X-ray crystallography, proton transfer, structure-activity relationships, a description of the REACH programs of the European Union for chemical regulatory purposes, reactions of nucleic acid bases with endogenous and exogenous reactive oxygen species and different aspects of nucleic acid bases, base pairs and base tetrads.

Computer Models in Biomechanics Book

Computer Models in Biomechanics


  • Author : Gerhard Holzapfel
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-10-17
  • Genre: Technology & Engineering
  • Pages : 406
  • ISBN 10 : 9789400754638

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Computer Models in Biomechanics Excerpt :

This book contains a collection of papers that were presented at the IUTAM Symposium on “Computer Models in Biomechanics: From Nano to Macro” held at Stanford University, California, USA, from August 29 to September 2, 2011. It contains state-of-the-art papers on: - Protein and Cell Mechanics: coarse-grained model for unfolded proteins, collagen-proteoglycan structural interactions in the cornea, simulations of cell behavior on substrates - Muscle Mechanics: modeling approaches for Ca2+–regulated smooth muscle contraction, smooth muscle modeling using continuum thermodynamical frameworks, cross-bridge model describing the mechanoenergetics of actomyosin interaction, multiscale skeletal muscle modeling - Cardiovascular Mechanics: multiscale modeling of arterial adaptations by incorporating molecular mechanisms, cardiovascular tissue damage, dissection properties of aortic aneurysms, intracranial aneurysms, electromechanics of the heart, hemodynamic alterations associated with arterial remodeling following aortic coarctation, patient-specific surgery planning for the Fontan procedure - Multiphasic Models: solutes in hydrated biological tissues, reformulation of mixture theory-based poroelasticity for interstitial tissue growth, tumor therapies of brain tissue, remodeling of microcirculation in liver lobes, reactions, mass transport and mechanics of tumor growth, water transport modeling in the brain, crack modeling of swelling porous media - Morphogenesis, Biological Tissues and Organs: mechanisms of brain morphogenesis, micromechanical modeling of anterior cruciate ligaments, mechanical characterization of the human liver, in vivo validation of predictive models for bone remodeling and mechanobiology, bridging scales in respiratory mechanics

Computer Methods in Biomechanics and Biomedical Engineering Book

Computer Methods in Biomechanics and Biomedical Engineering


  • Author : Amit Gefen
  • Publisher : Springer
  • Release Date : 2017-08-29
  • Genre: Technology & Engineering
  • Pages : 263
  • ISBN 10 : 9783319597645

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Computer Methods in Biomechanics and Biomedical Engineering Excerpt :

This edited volume collects the research results presented at the 14th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Tel Aviv, Israel, 2016. The topical focus includes, but is not limited to, cardiovascular fluid dynamics, computer modeling of tissue engineering, skin and spine biomechanics, as well as biomedical image analysis and processing. The target audience primarily comprises research experts in the field of bioengineering, but the book may also be beneficial for graduate students alike.

Tumors of the Central Nervous System  Volume 12 Book

Tumors of the Central Nervous System Volume 12


  • Author : M.A. Hayat
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-12
  • Genre: Medical
  • Pages : 386
  • ISBN 10 : 9789400772175

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Tumors of the Central Nervous System Volume 12 Excerpt :

As in the case of its eleven predecessors in the series Tumors of the Central Nervous System, this volume is distinguished for its thorough approach, its roster of 92 distinguished contributors representing 11 different countries and its detailed examination of leading-edge technology and methods. Volume 12: Molecular Mechanisms, Children’s Cancer, Treatments, and Radiosurgery offers a comprehensive review of the diagnosis, therapy and prognosis of brain and spinal cord tumors. Coverage extends to a large number of tumor types, including neuroblastoma, medulloblastoma, meningioma and chordoma. Molecular profiling of brain tumors to select appropriate therapy in clinical trials of brain tumors is discussed in detail, as is the classification/diagnosis of brain tumors based on function analysis. CDK6 as the molecular regulator of neuronal differentiation in the adult brain, and the role of aquaporins in human brain tumor growth are explained. Discussion also includes tumors affecting children, including neuroblastoma and medulloblastoma. A full chapter is devoted to the role of molecular genetic alterations in medulloblastoma, and another examines survival differences between children and adults with medulloblastoma. The use of various types of imaging methods to diagnose brain tumors is explained. In-depth discussion of treatment options includes stereotactic radiosurgery, endoscopic neurosurgery, electrochemotherapy, transsphenoidal surgery, focal ablation, whole brain radiation therapy and recraniotomy.

Military Injury Biomechanics Book

Military Injury Biomechanics


  • Author : Melanie Franklyn
  • Publisher : CRC Press
  • Release Date : 2017-06-12
  • Genre: Technology & Engineering
  • Pages : 418
  • ISBN 10 : 9781498742832

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Military Injury Biomechanics Excerpt :

Military Injury Biomechanics: The Cause and Prevention of Impact Injuries is a reference manual where information and data from a large number of sources, focussing on injuries related to military events, has been critically reviewed and discussed. The book covers the cause and prevention of impact injuries to all the major body regions, while topics such as the historical background of military impact biomechanics, the history and use of anthropomorphic test devices for military applications and the medical management of injuries are also discussed. An international team of experts have been brought together to examine and review the topics. The book is intended for researchers, postgraduate students and others working or studying defence and impact injuries.

Computational Biomechanics for Medicine Book

Computational Biomechanics for Medicine


  • Author : Poul M.F. Nielsen
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-05-02
  • Genre: Technology & Engineering
  • Pages : 140
  • ISBN 10 : 9781461431725

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Computational Biomechanics for Medicine Excerpt :

One of the greatest challenges for mechanical engineers is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, biomedical sciences, and medicine. This book is an opportunity for computational biomechanics specialists to present and exchange opinions on the opportunities of applying their techniques to computer-integrated medicine. Computational Biomechanics for Medicine: Deformation and Flow collects the papers from the Medical Image Computing and Computer Assisted Intervention conference (MICCAI 2011) dedicated to research in the field of medical image computing and computer assisted medical interventions. The topics covered include: medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, injury mechanism analysis, implant and prostheses design, and medical robotics.

Image Guided Interventions Book
Score: 5
From 1 Ratings

Image Guided Interventions


  • Author : Terry Peters
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-05-21
  • Genre: Technology & Engineering
  • Pages : 557
  • ISBN 10 : 9780387738581

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Image Guided Interventions Excerpt :

Responding to the growing demand for minimally invasive procedures, this book provides a comprehensive overview of the current technological advances in image-guided surgery. It blends the expertise of both engineers and physicians, offering the latest findings and applications. Detailed color images guide readers through the latest techniques, including cranial, orthopedic, prostrate, and endovascular interventions.

Clinical Image Based Procedures  Translational Research in Medical Imaging Book

Clinical Image Based Procedures Translational Research in Medical Imaging


  • Author : Cristina Oyarzun Laura
  • Publisher : Springer
  • Release Date : 2016-03-29
  • Genre: Computers
  • Pages : 132
  • ISBN 10 : 9783319318080

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Clinical Image Based Procedures Translational Research in Medical Imaging Excerpt :

This book constitutes revised selected papers from the 4th International Workshop on Clinical Image-Based Procedures, CLIP 2015, held in conjunction with MICCAI 2015 in Munich, Germany, in October 2015. The 15 papers presented in this volume were carefully reviewed and selected from 22 submissions. CLIP focuses on translational research; therefore, the goal of the works presented in this workshop is to bring basic research methods closer to the clinical practice. A highlight of this workshop is the subject of strategies for personalized medicine to enhance diagnosis, treatment and interventions.