Multiscale Biomechanics Book

Multiscale Biomechanics

  • Author : Jean-Francois Ganghoffer
  • Publisher : Elsevier
  • Release Date : 2018-02-03
  • Genre: Medical
  • Pages : 582
  • ISBN 10 : 9780081021156

Multiscale Biomechanics Excerpt :

Multiscale Biomechanics provides new insights on multiscale static and dynamic behavior of both soft and hard biological tissues, including bone, the intervertebral disk, biological membranes and tendons. The physiological aspects of bones and biological membranes are introduced, along with micromechanical models used to compute mechanical response. A modern account of continuum mechanics of growth and remodeling, generalized continuum models to capture internal lengths scales, and dedicated homogenization methods are provided to help the reader with the necessary theoretical foundations. Topics discussed include multiscale methods for fibrous media based on discrete homogenization, generalized continua constitutive models for bone, and a presentation of recent theoretical and numerical advances. In addition, a refresher on continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods is given in separate chapters. Numerical aspects are treated in detail, and simulations are presented to illustrate models. This book is intended for graduate students and researchers in biomechanics interested in the latest research developments, as well as those who wish to gain insight into the field of biomechanics. Provides a clear exposition of multiscale methods for fibrous media based on discrete homogenization and the consideration of generalized continua constitutive models for bone Presents recent theoretical and numerical advances for bone remodeling and growth Includes the necessary theoretical background that is exposed in a clear and self-contained manner Covers continuum mechanics and more advanced background related to differential geometry, configurational mechanics, mechanics of growth, thermodynamics of open systems and homogenization methods

Multiscale Biomechanics and Tribology of Inorganic and Organic Systems Book

Multiscale Biomechanics and Tribology of Inorganic and Organic Systems

  • Author : Georg-Peter Ostermeyer
  • Publisher : Springer Nature
  • Release Date : 2020-11-23
  • Genre: Science
  • Pages : 565
  • ISBN 10 : 9783030601249

Multiscale Biomechanics and Tribology of Inorganic and Organic Systems Excerpt :

This open access book gathers authoritative contributions concerning multiscale problems in biomechanics, geomechanics, materials science and tribology. It is written in memory of Sergey Grigorievich Psakhie to feature various aspects of his multifaceted research interests, ranging from theoretical physics, computer modeling of materials and material characterization at the atomic scale, to applications in space industry, medicine and geotectonics, and including organizational, psychological and philosophical aspects of scientific research and teaching as well. This book covers new advances relating to orthopedic implants, concerning the physiological, tribological and materials aspects of their behavior; medical and geological applications of permeable fluid-saturated materials; earthquake dynamics together with aspects relating to their managed and gentle release; lubrication, wear and material transfer in natural and artificial joints; material research in manufacturing processes; hard-soft matter interaction, including adhesive and capillary effects; using nanostructures for influencing living cells and for cancer treatment; manufacturing of surfaces with desired properties; self-organization of hierarchical structures during plastic deformation and thermal treatment; mechanics of composites and coatings; and many more. Covering established knowledge as well as new models and methods, this book provides readers with a comprehensive overview of the field, yet also with extensive details on each single topic.

Multiscale Biomechanical Modeling of the Brain Book

Multiscale Biomechanical Modeling of the Brain

  • Author : Mark F. Horstemeyer
  • Publisher : Academic Press
  • Release Date : 2021-10-27
  • Genre: Technology & Engineering
  • Pages : 276
  • ISBN 10 : 9780128181454

Multiscale Biomechanical Modeling of the Brain Excerpt :

Multiscale Biomechanical Modeling of the Brain discusses the constitutive modeling of the brain at various length scales (nanoscale, microscale, mesoscale, macroscale and structural scale). In each scale, the book describes the state-of-the- experimental and computational tools used to quantify critical deformational information at each length scale. Then, at the structural scale, several user-based constitutive material models are presented, along with real-world boundary value problems. Lastly, design and optimization concepts are presented for use in occupant-centric design frameworks. This book is useful for both academia and industry applications that cover basic science aspects or applied research in head and brain protection. The multiscale approach to this topic is unique, and not found in other books. It includes meticulously selected materials that aim to connect the mechanistic analysis of the brain tissue at size scales ranging from subcellular to organ levels. Presents concepts in a theoretical and thermodynamic framework for each length scale Teaches readers not only how to use an existing multiscale model for each brain but also how to develop a new multiscale model Takes an integrated experimental-computational approach and gives structured multiscale coverage of the problems

Multiphysics and Multiscale Modeling Book

Multiphysics and Multiscale Modeling

  • Author : Young W. Kwon
  • Publisher : CRC Press
  • Release Date : 2015-10-05
  • Genre: Science
  • Pages : 426
  • ISBN 10 : 9781482244595

Multiphysics and Multiscale Modeling Excerpt :

Written to appeal to a wide field of engineers and scientists who work on multiscale and multiphysics analysis, Multiphysics and Multiscale Modeling: Techniques and Applications is dedicated to the many computational techniques and methods used to develop man-made systems as well as understand living systems that exist in nature. Presenting a body

Multiscale Mechanobiology in Tissue Engineering Book

Multiscale Mechanobiology in Tissue Engineering

  • Author : Damien Lacroix
  • Publisher : Springer
  • Release Date : 2018-07-31
  • Genre: Science
  • Pages : 203
  • ISBN 10 : 9789811080753

Multiscale Mechanobiology in Tissue Engineering Excerpt :

This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

Biomechanics Book


  • Author : Manuel Doblare
  • Publisher : EOLSS Publications
  • Release Date : 2015-12-30
  • Genre: Uncategoriezed
  • Pages : 498
  • ISBN 10 : 9781780210230

Biomechanics Excerpt :

Biomechanics is a component of Encyclopedia of Physical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The enormous progress in the field of health sciences that has been achieved in the 19th and 20th centuries would have not been possible without the enabling interaction and support of sophisticated technologies that progressively gave rise to a new interdisciplinary field named alternatively as bioengineering or biomedical engineering. Although both terms are synonymous, the latter is less general since it limits the field of application to medicine and clinical practice, while the former covers semantically the whole field of interaction between life sciences and engineering, thus including also applications in biology, biochemistry or the many '-omics'. We use in this book the second, with more general meaning, recalling the very important relation between fundamental science and engineering. And this also recognizes the tremendous economic and social impacts of direct application of engineering in medicine that maintains the health industry as one with the fastest growth in the world economy. Biomechanics, in particular, aims to explain and predict the mechanics of the different components of living beings, from molecules to organisms as well as to design, manufacture and use of any artificial device that interacts with the mechanics of living beings. It helps, therefore, to understand how living systems move, to characterize the interaction between forces and deformation along all spatial scales, to analyze the interaction between structural behavior and microstructure, with the very important particularity of dealing with adaptive systems, able to adapt their internal structure, size and geometry to the particular mechanical environment in which they develop their activity, to understand and predict alterations in the mechanical function

Computational Biomechanics Book

Computational Biomechanics

  • Author : Masao Tanaka
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-06-16
  • Genre: Technology & Engineering
  • Pages : 196
  • ISBN 10 : 9784431540724

Computational Biomechanics Excerpt :

Rapid developments have taken place in biological/biomedical measurement and imaging technologies as well as in computer analysis and information technologies. The increase in data obtained with such technologies invites the reader into a virtual world that represents realistic biological tissue or organ structures in digital form and allows for simulation and what is called “in silico medicine.” This volume is the third in a textbook series and covers both the basics of continuum mechanics of biosolids and biofluids and the theoretical core of computational methods for continuum mechanics analyses. Several biomechanics problems are provided for better understanding of computational modeling and analysis. Topics include the mechanics of solid and fluid bodies, fundamental characteristics of biosolids and biofluids, computational methods in biomechanics analysis/simulation, practical problems in orthopedic biomechanics, dental biomechanics, ophthalmic biomechanics, cardiovascular biomechanics, hemodynamics, cell mechanics, and model-, rule-, and image-based methods in computational biomechanics analysis and simulation. The book is an excellent resource for graduate school-level engineering students and young researchers in bioengineering and biomedicine.

Materials and Devices for Bone Disorders Book

Materials and Devices for Bone Disorders

  • Author : Susmita Bose
  • Publisher : Academic Press
  • Release Date : 2016-11-03
  • Genre: Technology & Engineering
  • Pages : 560
  • ISBN 10 : 9780128028032

Materials and Devices for Bone Disorders Excerpt :

Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored. Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts Includes input from a world-class team of research scientists, engineers, and clinicians Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System Book

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System

  • Author : Zhongmin Jin
  • Publisher : Woodhead Publishing
  • Release Date : 2020-09-29
  • Genre: Technology & Engineering
  • Pages : 632
  • ISBN 10 : 9780128227626

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System Excerpt :

Computational Modelling of Biomechanics and Biotribology in the Musculoskeletal System: Biomaterials and Tissues, Second Edition reviews how a wide range of materials are modeled and applied. Chapters cover basic concepts for modeling of biomechanics and biotribology, the fundamentals of computational modeling of biomechanics in the musculoskeletal system, finite element modeling in the musculoskeletal system, computational modeling from a cells and tissues perspective, and computational modeling of the biomechanics and biotribology interactions, looking at complex joint structures. This book is a comprehensive resource for professionals in the biomedical market, materials scientists and biomechanical engineers, and academics in related fields. This important new edition provides an up-to-date overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application, including new content on novel technologies, biomorphic hydroxyapatite and more. Provides detailed, introductory coverage of modeling of cells and tissues, modeling of biomaterials and interfaces, biomechanics and biotribology Discusses applications of modeling for joint replacements and applications of computational modeling in tissue engineering Offers a holistic perspective, from cells and small ligaments to complex joint interactions

Structure and Function of the Extracellular Matrix Book

Structure and Function of the Extracellular Matrix

  • Author : Bela Suki
  • Publisher : Academic Press
  • Release Date : 2021-12-06
  • Genre: Technology & Engineering
  • Pages : 282
  • ISBN 10 : 9780128226056

Structure and Function of the Extracellular Matrix Excerpt :

Structure and Function of the Extracellular Matrix: A Multiscale Quantitative Approach introduces biomechanics and biophysics with applications to understand the biological function of the extracellular matrix in health and disease. A general multiscale approach is followed by investigating behavior from the scale of single molecules, through fibrils and fibers, to tissues of various organ systems. Through mathematical models and structural information, quantitative description of the extracellular matrix function is derived with tissue specific details. The book introduces the properties and organization of extracellular matrix components and quantitative models of the matrix, and guides the reader through predicting functional properties. This book integrates evolutionary biology with multiscale structure to quantitatively understand the function of the extracellular matrix. This approach allows a fresh look into normal functioning as well as the pathological alterations of the extracellular matrix. Professor Suki’s book is written to be useful to undergraduates, graduate students, and researchers interested in the quantitative aspects of the extracellular matrix. Researchers working in mechanotransduction, respiratory and cardiovascular mechanics, and multiscale biomechanics of tendon, cartilage, skin, and bone may also be interested in this book. Examines the evolutionary origins and consequences of the extracellular matrix Delivers the first book to quantitatively treat the extracellular matrix as a multiscale system Presents problems and a set of computational laboratory projects in various chapters to aid teaching and learning Provides an introduction to the properties and organization of the extracellular matrix components

Advances in Heterogeneous Material Mechanics 2011 Book

Advances in Heterogeneous Material Mechanics 2011

  • Author : Jinghong Fan
  • Publisher : DEStech Publications, Inc
  • Release Date : 2011
  • Genre: Technology & Engineering
  • Pages : 1174
  • ISBN 10 : 9781605950549

Advances in Heterogeneous Material Mechanics 2011 Excerpt :

The third book in a series on heterogeneous materials, this volume offers integrated approaches to the measurement and modeling of materials using approaches from materials science, physics, mechanics, biology and other disciplines. The volume contains 289 chapters presenting original research on the connections among the nano- , micro-, and mesoscale mechanical properties and behaviors of many different types of engineered and natural heterogeneous materials. The book contains a wealth of never published multiscale data on materials loading behaviors, plasticity, creep, damage, fracture and failure. A separate section is devoted to the design and functionalization of materials using multiscale data and techniques

Human Orthopaedic Biomechanics Book

Human Orthopaedic Biomechanics

  • Author : Bernardo Innocenti
  • Publisher : Academic Press
  • Release Date : 2022-02-24
  • Genre: Technology & Engineering
  • Pages : 758
  • ISBN 10 : 9780128244821

Human Orthopaedic Biomechanics Excerpt :

Human Orthopaedic Biomechanics: Fundamentals, Devices and Applications covers a wide range of biomechanical topics and fields, ranging from theoretical issues, mechanobiology, design of implants, joint biomechanics, regulatory issues and practical applications. The book teaches the fundamentals of physiological loading and constraint conditions at various parts of the musculoskeletal system. It is an ideal resource for teaching and education in courses on orthopedic biomechanics, and for engineering students engaged in these courses. In addition, all bioengineers who have an interest in orthopedic biomechanics will find this title useful as a reference, particularly early career researchers and industry professionals. Finally, any orthopedic surgeons looking to deepen their knowledge of biomechanical aspects will benefit from the accessible writing style in this title. Covers theoretical aspects (mechanics, stress analysis, constitutive laws for the various musculoskeletal tissues and mechanobiology) Presents components of different regulatory aspects, failure analysis, post-marketing and clinical trials Includes state-of-the-art methods used in orthopedic biomechanics and in designing orthopedic implants (experimental methods, finite element and rigid-body models, gait and fluoroscopic analysis, radiological measurements)

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes Book

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes

  • Author : Miguel Cerrolaza
  • Publisher : Academic Press
  • Release Date : 2017-10-17
  • Genre: Technology & Engineering
  • Pages : 454
  • ISBN 10 : 9780128117194

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes Excerpt :

Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes covers new and exciting modeling methods to help bioengineers tackle problems for which the Finite Element Method is not appropriate. The book covers a wide range of important subjects in the field of numerical methods applied to biomechanics, including bone biomechanics, tissue and cell mechanics, 3D printing, computer assisted surgery and fluid dynamics. Modeling strategies, technology and approaches are continuously evolving as the knowledge of biological processes increases. Both theory and applications are covered, making this an ideal book for researchers, students and R&D professionals. Provides non-conventional analysis methods for modeling Covers the Discrete Element Method (DEM), Particle Methods (PM), MessLess and MeshFree Methods (MLMF), Agent-Based Methods (ABM), Lattice-Boltzmann Methods (LBM) and Boundary Integral Methods (BIM) Includes contributions from several world renowned experts in their fields Compares pros and cons of each method to help you decide which method is most applicable to solving specific problems

Multiscale Biomechanics and Tribology of Inorganic and Organic Systems Book

Multiscale Biomechanics and Tribology of Inorganic and Organic Systems

  • Author : Georg-Peter Ostermeyer
  • Publisher : Springer
  • Release Date : 2020-12-25
  • Genre: Uncategoriezed
  • Pages : 584
  • ISBN 10 : 3030601269

Multiscale Biomechanics and Tribology of Inorganic and Organic Systems Excerpt :

In Memory of Professor Sergey Grigorievich Psakhie.- Biomechanical and Tribological Aspects of Orthopaedic Implants.- A New Method for Seismically Safe Managing of Seismotectonic Deformations in Fault Zones.- Particle-Based Approach for Simulation of Nonlinear Material Behavior in Contact Zones.- A Tool for Studying the Mechanical Behavior of the Bone-Endoprosthesis System Based on Multi-scale Simulation.- Abstract Methods on Mesoscopic Scales of Friction.- Study of Dynamics of Block-Media in the Framework of Minimalistic Numerical Models.- Material Transfer by Friction Stir Processing.- Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies.- Application of Crumpled Aluminum Hydroxide Nanostructures for Cancer Treatment.- Influence of Lattice Curvature and Nanoscale Mesoscopic Structural States on the Wear Resistance and Fatigue Life of Austenitic Steel.- Autowave Mechanics of Plastic Flow.- Three-Component Wear-Resistant PEEK-Based Composites Filled with PTFE and MoS2: Composition Optimization, Structure Homogenization, and Self-Lubricating Effect.- Regularities of Structural Rearrangements in Single- and Bicrystals Near the Contact Zone.- Fault Sliding Modes - Governing, Evolution and Transformation.- Multilayer Modelling of Lubricated Contacts: A New Approach Based on a Potential Field Description.- Microstructure-Based Computational Analysis of Deformation and Fracture in Composite and Coated Materials Across Multiple Spatial Scales.- Formation of a Nanostructured Hardened Surface Layer on the TiC-(Ni-Cr) Metal-Ceramic Alloy by Pulsed Electron-Beam Irradiation.- Adhesion of a Thin Soft Matter Layer: The Role of Surface Tension.- Adhesion Hysteresis Due to Chemical Heterogeneity.- Theoretical Study of Physico-Mechanical Response of Permeable Fluid-Saturated Materials under Complex Loading Based on the Hybrid Cellular Automaton Method.- Transfer of a Biological Fluid Through a Porous Wall of a Capillary.- Failure Mechanisms of Alloys with a Bi

Biomaterials and Engineering for Implantology Book

Biomaterials and Engineering for Implantology

  • Author : Yoshiki Oshida
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release Date : 2022-02-07
  • Genre: Medical
  • Pages : 571
  • ISBN 10 : 9783110740134

Biomaterials and Engineering for Implantology Excerpt :

Biomaterials are composed of metallic materials, ceramics, polymers, composites and hybrid materials. Biomaterials used in human beings require safety regulations, toxicity, allergic reaction, etc. When used as implantable materials their biological compatibility, biomechanical compatibility, and morphological compatibility must be acessed. This book explores the design and requirements of biomaterials for the use in implantology.