Nanoparticulate Drug Delivery Book

Nanoparticulate Drug Delivery


  • Author : Vandana Patravale
  • Publisher : Elsevier
  • Release Date : 2012-10-31
  • Genre: Medical
  • Pages : 244
  • ISBN 10 : 9781908818195

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Nanoparticulate Drug Delivery Excerpt :

Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments. Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation Provides an overview of new application areas, including RNA interference Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector

Nanoparticulate Drug Delivery Systems Book

Nanoparticulate Drug Delivery Systems


  • Author : Yoon Yeo
  • Publisher : John Wiley & Sons
  • Release Date : 2013-02-25
  • Genre: Science
  • Pages : 324
  • ISBN 10 : 9781118570517

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Nanoparticulate Drug Delivery Systems Excerpt :

Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.

Nanoparticulate Drug Delivery Systems Book

Nanoparticulate Drug Delivery Systems


  • Author : Raj K. Keservani
  • Publisher : CRC Press
  • Release Date : 2019-01-23
  • Genre: Medical
  • Pages : 422
  • ISBN 10 : 9781351137256

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Nanoparticulate Drug Delivery Systems Excerpt :

Focusing on nanoparticulate nanocarriers and recent advances in the field of drug delivery, the volume begins with chapters that provide an informative introduction to polymeric nanoparticles—their general physicochemical features and characteristics, their applications in drug delivery systems, and the challenges involved. Specific applications are discussed, with attention paid to treatment of particular diseases and disorders and the targeting of specific organs. Part 2 looks at more specific applications and techniques of nanoparticulate nanocarriers for drug delivery, such as the use of magnetic nanoparticles, gold nanoparticles in therapeutics, and superparamagnetic iron oxide nanoparticles (SPIONs) for the treatment of cancer. Part 3 discusses lipid-based nanoparticulates for various applications, including skin care. The last section of the book explores some of the newer nanoarchitectures, including dendrimers in gene delivery and carbon nanotubes for drug delivery. Together, the insightful research presented here provides valuable information for those involved in this area, including scientists and researchers and faculty and upper-level students, as well as for industry professionals.

Nanoparticulate Drug Delivery Systems Book
Score: 3
From 3 Ratings

Nanoparticulate Drug Delivery Systems


  • Author : Deepak Thassu
  • Publisher : CRC Press
  • Release Date : 2007-03-30
  • Genre: Medical
  • Pages : 376
  • ISBN 10 : 9781420008449

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Nanoparticulate Drug Delivery Systems Excerpt :

With the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. Nanoparticulate Drug Delivery Systems addresses the scientific methodologies, formulation, processing, applications, recent trends, and e

Drug Delivery with Targeted Nanoparticles Book

Drug Delivery with Targeted Nanoparticles


  • Author : Yılmaz Çapan
  • Publisher : CRC Press
  • Release Date : 2021-11-30
  • Genre: Medical
  • Pages : 790
  • ISBN 10 : 9781000375305

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Drug Delivery with Targeted Nanoparticles Excerpt :

Nanotechnology has the potential to change every part of our lives. Today, nanotechnology-based products are used in many areas, and one of the most important areas is drug delivery. Nanoparticulate drug delivery systems not only provide controlled delivery of drugs and improved drug solubility but also improve drug efficiency and reduce side effects via targeting mechanisms. However, compared with conventional drug delivery systems, few nanoparticle-based products are on the market and almost all are nontargeted or only passively targeted systems. In addition, obtaining targeted nanoparticle systems is quite complex and requires several evaluation mechanisms. This book discusses the production, characterization, regulation, and currently marketed targeted nanoparticle systems in a broad framework. It provides an overview of targeted nanoparticles’ (i) in vitro characterization, such as particle size, stability, ligand density, and type; (ii) in vivo behavior for different targeting areas, such as tumor, brain, and vagina; and (iii) current advances in this field, including clinical trials and regulation processes.

Nanoparticulates as Drug Carriers Book
Score: 4
From 3 Ratings

Nanoparticulates as Drug Carriers


  • Author : V. P. Torchilin
  • Publisher : Imperial College Press
  • Release Date : 2006
  • Genre: Technology & Engineering
  • Pages : 724
  • ISBN 10 : 9781860949074

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Nanoparticulates as Drug Carriers Excerpt :

Written by key experts in the field of nanomedicine, this book provides a broad introduction to the important field of nanomedicine and application of nanotechnology for drug delivery. It covers up-to-date information regarding various nanoparticulate drug delivery systems, describes the various opportunities for the application of nanoparticular drug carriers in different areas of clinical medicine, and analyzes already available information on their clinical applications. This book can be used as an advanced textbook by graduate students and young scientists and clinicians at the early stages of their career. It is also suitable for non-experts from related areas of chemistry, biochemistry, molecular biology, biomedical engineering, physiology, experimental and clinical medicine, and pharmaceutical sciences, who are interested in general problems of drug delivery and drug targeting, as well as in more specialized topics of using nanoparticulate-mediated drug delivery approaches in the individual areas of clinical medicine. Prof Torchilin is an expert in Nanomedicine and a recipient of numerous awards including the Lenin Prize in Science & Technology of the former USSR, membership in the European Academy of Sciences, and AAPS Research Achievement Award in Pharmaceutics and Drug Delivery. He served as an Associate Professor of Radiology at Harvard Medical School before joining Northeastern University as the Chairman of the Department of Pharmaceutical Sciences. Sample Chapter(s). Chapter 1: Introduction. Nanocarriers for Drug Delivery: Needs and Requirements (442 KB). Contents: Nanoparticle Flow: Implications for Drug Delivery (A T Florence); Polymer Micelles as Drug Carriers (E V Batrakova et al.); Lipoproteins as Pharmaceutical Carriers (S Liu et al.); Dendrimers as Nanoparticular Drug Carriers (S Svenson & D A Tomalia); Cells and Cell Ghosts as Drug Carriers (J M Lanao & M L Sayalero); Magnetic Nanoparticles as Drug Carriers (U O Hnfeli & M Chastellain); Liposoma

Nanoparticles in Pharmacotherapy Book

Nanoparticles in Pharmacotherapy


  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release Date : 2019-04-15
  • Genre: Medical
  • Pages : 600
  • ISBN 10 : 9780128165041

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Nanoparticles in Pharmacotherapy Excerpt :

Nanoparticles in Pharmacotherapy explores the most recent findings in how nanoparticles used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. Offering he book will be a valuable resource of recent scientific progress, along with most known applications of nanoparticles on the pharmacotherapy to be used by researchers, medical doctors and academia individuals.

Metal Nanoparticles for Drug Delivery and Diagnostic Applications Book

Metal Nanoparticles for Drug Delivery and Diagnostic Applications


  • Author : Muhammad Raza Shah
  • Publisher : Micro & Nano Technologies
  • Release Date : 2019-10-22
  • Genre: Uncategoriezed
  • Pages : 356
  • ISBN 10 : 9780128169605

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Metal Nanoparticles for Drug Delivery and Diagnostic Applications Excerpt :

Metal Nanoparticles for Drug Delivery and Diagnostic Applications addresses the lifecycle of metal nanoparticles, from synthesis and characterization, to applications in drug delivery and targeting. It is an important resource for those in biomaterials, nanomedicine and pharmaceutical sciences, exploring gold, silver and iron-based drug delivery systems for controlled and targeted delivery of potential drugs and genes for enhanced clinical efficacy. Nanotechnology is widely used in drug delivery due to its ability to reduce plasma fluctuation of drugs, high solubility, and efficiency, the relatively low cost of nanoscale products, and enhancement of patient comfort, hence this resource is a welcome edition to the science. Illustrates the progression of nanoparticle therapeutics from basic research to applications Explores new opportunities and ideas for developing and improving technologies in nanomedicine and nanobiology Discusses the toxicity of different types of metal nanoparticles and how to ensure their safe use

Nanoparticle Drug Delivery Systems for Cancer Treatment Book

Nanoparticle Drug Delivery Systems for Cancer Treatment


  • Author : Hala Gali-Muhtasib
  • Publisher : CRC Press
  • Release Date : 2020-02-19
  • Genre: Medical
  • Pages : 326
  • ISBN 10 : 9781000681413

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Nanoparticle Drug Delivery Systems for Cancer Treatment Excerpt :

In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Nanomaterials for Drug Delivery and Therapy Book
Score: 5
From 1 Ratings

Nanomaterials for Drug Delivery and Therapy


  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release Date : 2019-03-14
  • Genre: Medical
  • Pages : 580
  • ISBN 10 : 9780128166291

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Nanomaterials for Drug Delivery and Therapy Excerpt :

Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including neurology, dentistry and cancer therapy. Authored by a range of contributors from global institutions, this book offers a broad, international perspective on how nanotechnology-based advances are leading to novel drug delivery and treatment solutions. It is a valuable research resource that will help both practicing medics and researchers in pharmaceutical science and nanomedicine learn more on how nanotechnology is improving treatments. Assesses the opportunities and challenges of nanotechnology-based drug delivery systems Explores how nanotechnology is being used to create more efficient drug delivery systems Discusses which nanomaterials make the best drug carriers

Nanoparticles in the Lung Book

Nanoparticles in the Lung


  • Author : Akira Tsuda
  • Publisher : CRC Press
  • Release Date : 2014-12-19
  • Genre: Medical
  • Pages : 403
  • ISBN 10 : 9781439892800

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Nanoparticles in the Lung Excerpt :

Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding

Recent Advances in Novel Drug Carrier Systems Book

Recent Advances in Novel Drug Carrier Systems


  • Author : Ali Demir Sezer
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-10-31
  • Genre: Medical
  • Pages : 514
  • ISBN 10 : 9789535108108

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Recent Advances in Novel Drug Carrier Systems Excerpt :

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, pulmonary, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.

Drug Delivery Using Nanomaterials Book

Drug Delivery Using Nanomaterials


  • Author : Yasser Shahzad
  • Publisher : CRC Press
  • Release Date : 2022-01-19
  • Genre: Medical
  • Pages : 430
  • ISBN 10 : 9781000529494

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Drug Delivery Using Nanomaterials Excerpt :

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation. FEATURES Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Nanoparticles for Drug Delivery Book

Nanoparticles for Drug Delivery


  • Author : Joshy K. S.
  • Publisher : Springer Nature
  • Release Date : 2021
  • Genre: Biomedical engineering
  • Pages : 207
  • ISBN 10 : 9789811621192

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Nanoparticles for Drug Delivery Excerpt :

This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

Drug Delivery Nanoparticles Formulation and Characterization Book

Drug Delivery Nanoparticles Formulation and Characterization


  • Author : Yashwant Pathak
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Genre: Medical
  • Pages : 416
  • ISBN 10 : 9781420078053

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Drug Delivery Nanoparticles Formulation and Characterization Excerpt :

Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na