Neuronal Networks in Brain Function  CNS Disorders  and Therapeutics Book

Neuronal Networks in Brain Function CNS Disorders and Therapeutics

  • Author : Carl Faingold
  • Publisher : Academic Press
  • Release Date : 2013-12-26
  • Genre: Medical
  • Pages : 512
  • ISBN 10 : 9780124158641

Neuronal Networks in Brain Function CNS Disorders and Therapeutics Excerpt :

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

From Neurons to Neighborhoods Book
Score: 5
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From Neurons to Neighborhoods

  • Author : Division of Behavioral and Social Sciences and Education
  • Publisher : National Academies Press
  • Release Date : 2000-11-13
  • Genre: Social Science
  • Pages : 612
  • ISBN 10 : 9780309069885

From Neurons to Neighborhoods Excerpt :

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Sudden Unexpected Death in Epilepsy Book

Sudden Unexpected Death in Epilepsy

  • Author : Claire M. Lathers
  • Publisher : CRC Press
  • Release Date : 2015-04-06
  • Genre: Law
  • Pages : 350
  • ISBN 10 : 9781482223880

Sudden Unexpected Death in Epilepsy Excerpt :

Sudden Unexpected Death in Epilepsy: Mechanisms and New Methods for Analyzing Risks builds on earlier works focusing on the clinical problem of sudden unexpected death in epilepsy (SUDEP). This book presents a methodology for identifying and classifying clusters of risks that lead to SUDEP. Developed over the last two years, the SUDEP Classificatio

New Therapeutics for Traumatic Brain Injury Book

New Therapeutics for Traumatic Brain Injury

  • Author : Kim Heidenreich
  • Publisher : Academic Press
  • Release Date : 2016-09-27
  • Genre: Medical
  • Pages : 352
  • ISBN 10 : 9780128027011

New Therapeutics for Traumatic Brain Injury Excerpt :

New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. Comprehensive overview of basic approaches and translational development of new therapies for TBI Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic

The Physics of the Mind and Brain Disorders Book

The Physics of the Mind and Brain Disorders

  • Author : Ioan Opris
  • Publisher : Springer
  • Release Date : 2017-12-01
  • Genre: Medical
  • Pages : 793
  • ISBN 10 : 9783319296746

The Physics of the Mind and Brain Disorders Excerpt :

This book covers recent advances in the understanding of brain structure, function and disorders based on the fundamental principles of physics. It covers a broad range of physical phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the mind. It provides novel insights into the devastating brain disorders of the mind such as schizophrenia, dementia, autism, aging or addictions, as well as into the new devices for brain repair. The book is aimed at basic researchers in the fields of neuroscience, physics, biophysics and clinicians in the fields of neurology, neurosurgery, psychology, psychiatry.

Tinnitus  Imaging  Endovascular and Surgical Approaches  An issue of Neuroimaging Clinics of North America  E Book Book

Tinnitus Imaging Endovascular and Surgical Approaches An issue of Neuroimaging Clinics of North America E Book

  • Author : Prashant Raghavan
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-07-27
  • Genre: Medical
  • Pages : 145
  • ISBN 10 : 9780323444743

Tinnitus Imaging Endovascular and Surgical Approaches An issue of Neuroimaging Clinics of North America E Book Excerpt :

This issue of Neuroimaging Clinics of North America focuses on Imaging of Tinnitus. Articles will include: Neuroscience of Tinnitus; Clinical Evaluation of the Patient with Tinnitus; Arterial Abnormalities Leading to Tinnitus; Paragangliomas and Other Vascular Skull Base Tumors; Dural AV Fistulae: Imaging and Management; Venous Abnormalities Leading to Tinnitus: Imaging Evaluation; Endovascular Intervention in Venous Tinnitus: New Horizons and Future Directions; Emerging Role of Surgical Treatments in the Treatment of Tinnitus; Role of Advanced Neuroimaging and Future Directions; Imaging Interpretation of Temporal Bone Studies in a Patient with Tinnitus: A Systematic Approach; and much more!

Models of Seizures and Epilepsy Book

Models of Seizures and Epilepsy

  • Author : Asla Pitkänen
  • Publisher : Academic Press
  • Release Date : 2017-06-14
  • Genre: Science
  • Pages : 1178
  • ISBN 10 : 9780128040676

Models of Seizures and Epilepsy Excerpt :

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Almost Periodicity  Chaos  and Asymptotic Equivalence Book

Almost Periodicity Chaos and Asymptotic Equivalence

  • Author : Marat Akhmet
  • Publisher : Springer
  • Release Date : 2019-06-20
  • Genre: Technology & Engineering
  • Pages : 360
  • ISBN 10 : 9783030205720

Almost Periodicity Chaos and Asymptotic Equivalence Excerpt :

The central subject of this book is Almost Periodic Oscillations, the most common oscillations in applications and the most intricate for mathematical analysis. Prof. Akhmet's lucid and rigorous examination proves these oscillations are a "regular" component of chaotic attractors. The book focuses on almost periodic functions, first of all, as Stable (asymptotically) solutions of differential equations of different types, presumably discontinuous; and, secondly, as non-isolated oscillations in chaotic sets. Finally, the author proves the existence of Almost Periodic Oscillations (asymptotic and bi-asymptotic) by asymptotic equivalence between systems. The book brings readers' attention to contemporary methods for considering oscillations as well as to methods with strong potential for study of chaos in the future. Providing three powerful instruments for mathematical research of oscillations where dynamics are observable and applied, the book is ideal for engineers as well as specialists in electronics, computer sciences, robotics, neural networks, artificial networks, and biology. Distinctively combines results and methods of the theory of differential equations with thorough investigation of chaotic dynamics with almost periodic ingredients; Provides all necessary mathematical basics in their most developed form, negating the need for any additional sources for readers to start work in the area; Presents a unique method of investigation of discontinuous almost periodic solutions in its unified form, employed to differential equations with different types of discontinuity; Develops the equivalence method to its ultimate effective state such that most important theoretical problems and practical applications can be analyzed by the method.

Sigma Receptors  Their Role in Disease and as Therapeutic Targets Book

Sigma Receptors Their Role in Disease and as Therapeutic Targets

  • Author : Sylvia B. Smith
  • Publisher : Springer
  • Release Date : 2017-03-16
  • Genre: Medical
  • Pages : 312
  • ISBN 10 : 9783319501741

Sigma Receptors Their Role in Disease and as Therapeutic Targets Excerpt :

Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types. It’s putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors. Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein.

Neural Approaches to Dynamics of Signal Exchanges Book

Neural Approaches to Dynamics of Signal Exchanges

  • Author : Anna Esposito
  • Publisher : Springer Nature
  • Release Date : 2019-09-18
  • Genre: Technology & Engineering
  • Pages : 525
  • ISBN 10 : 9789811389504

Neural Approaches to Dynamics of Signal Exchanges Excerpt :

The book presents research that contributes to the development of intelligent dialog systems to simplify diverse aspects of everyday life, such as medical diagnosis and entertainment. Covering major thematic areas: machine learning and artificial neural networks; algorithms and models; and social and biometric data for applications in human–computer interfaces, it discusses processing of audio-visual signals for the detection of user-perceived states, the latest scientific discoveries in processing verbal (lexicon, syntax, and pragmatics), auditory (voice, intonation, vocal expressions) and visual signals (gestures, body language, facial expressions), as well as algorithms for detecting communication disorders, remote health-status monitoring, sentiment and affect analysis, social behaviors and engagement. Further, it examines neural and machine learning algorithms for the implementation of advanced telecommunication systems, communication with people with special needs, emotion modulation by computer contents, advanced sensors for tracking changes in real-life and automatic systems, as well as the development of advanced human–computer interfaces. The book does not focus on solving a particular problem, but instead describes the results of research that has positive effects in different fields and applications.

Mechanisms of Neuroinflammation Book

Mechanisms of Neuroinflammation

  • Author : Gonzalo Emiliano Aranda Abreu
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-08-23
  • Genre: Medical
  • Pages : 318
  • ISBN 10 : 9789535134510

Mechanisms of Neuroinflammation Excerpt :

"Mechanisms of Neuroinflammation" book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation. A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.

Molecular and Cell Biology of Human Gene Therapeutics Book

Molecular and Cell Biology of Human Gene Therapeutics

  • Author : G. Dickson
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 403
  • ISBN 10 : 9789401105477

Molecular and Cell Biology of Human Gene Therapeutics Excerpt :

advanced metastatic disease of solid tumors, dictates that each tumor mass, indeed each individual metastasis, will have a unique antigen and cytokine environment and hence unique response to immune modu lation. A differential response to immunotherapy is thus inevitable. 4. Many of the human trials described are not randomized and report survival or response against historical controls. Most tumors described are immunogenic human tumors: renal cell cancer and melanoma are most common. In order to avoid the well-described inter-patient vari ation and rare incidence of spontaneous response among patient samples as well as selection bias and changes in practice over time, randomized trials are required. 5. Immunological treatment is unlike conventional chemotherapy in its endpoint. Most chemotherapeutic regimes require a complete response or a good partial response for cure or good palliation. There are now many cases where immunotherapy has provided long-term palliation without massive tumor reduction. Immunity may be stimulated to a degree which holds tumorigenicity in check and most importantly, pro vides good palliation for the patient in a manner that differs essentially from chemotherapy.