Non Enzymatic Protein Modifications in Health  Disease and Ageing Book

Non Enzymatic Protein Modifications in Health Disease and Ageing


  • Author : Izabela Sadowska-Bartosz
  • Publisher : Academic Press
  • Release Date : 2018-11-15
  • Genre: Uncategoriezed
  • Pages : 252
  • ISBN 10 : 0128143053

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Non Enzymatic Protein Modifications in Health Disease and Ageing Excerpt :

There is increased understanding of the fate of intracellular and extracellular proteins, including the many types of posttranslational modifications that proteins undergo. Among these modifications, non-enzymatic protein modifications play a special role. These are unavoidable products of side reactions of reactive metabolites, and often damage proteins and induce loss of function. Non-Enzymatic Protein Modifications in Health, Diseases and Ageing discusses each type of non-enzymatic protein, both introducing non-enzymatic protein modifications, and reviewing the state of the art, presenting updates and current trends. The book covers various aspects of the subject, including formation and removal of modified proteins, their roles in disease, preventative methods, and possible roles in cellular signalling. Finally, the book not only provides well-established facts, but also discusses current hypotheses and controversies. Provides the basic chemical knowledge necessary to understand non-enzymatic protein modifications, of particular use to researchers looking for an introduction to and overview of the field Combines a systematic chemical introduction to non-enzymatic protein modifications with a review of the state of the art Presents together, types of non-enzymatic protein usually reported and reviewed separately Considers current hypotheses and controversies alongside the facts

Molecular Basis and Emerging Strategies for Anti aging Interventions Book

Molecular Basis and Emerging Strategies for Anti aging Interventions


  • Author : Syed Ibrahim Rizvi
  • Publisher : Springer
  • Release Date : 2018-11-02
  • Genre: Medical
  • Pages : 386
  • ISBN 10 : 9789811316999

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Molecular Basis and Emerging Strategies for Anti aging Interventions Excerpt :

This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.

Protein Metabolism and Homeostasis in Aging Book

Protein Metabolism and Homeostasis in Aging


  • Author : Nektarios Tavernarakis
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-01-11
  • Genre: Medical
  • Pages : 249
  • ISBN 10 : 9781441970022

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Protein Metabolism and Homeostasis in Aging Excerpt :

Aging is loosely defined as the accumulation of changes in an organism over time. At the cellular level such changes are distinct and multidimensional: DNA replication ceases, cells stop dividing, they become senescent and eventually die. DNA metabolism and chromosomal maintenance, together with protein metabolism are critical in the aging process. The focus of this book is on the role of protein metabolism and homeostasis in aging. An overview is provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well-characterised factors and pathways, but new areas are also presented, where associations with aging are just being elucidated by current experimental data. Protein turnover, the balance between protein synthesis and protein degradation are carefully maintained in healthy cells. Chapters 1 and 2 illustrate that aging cells are characterised by alterations in the rate, level and accuracy of protein synthesis compared to young ones, and that mRNA translation, essential for cell growth and survival, is controlled at multiple levels. The theory that growth and somatic maintenance are believed to be antagonistic processes is described in Chapter 3: inhibition of protein synthesis results in decreased rates of growth and development, but also confers an extension of lifespan, as shown for example by the effects of dietary restriction in various models organisms.

The Aging Kidney in Health and Disease Book

The Aging Kidney in Health and Disease


  • Author : Juan F. Macías-Núñez
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-24
  • Genre: Medical
  • Pages : 553
  • ISBN 10 : 9780387726595

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The Aging Kidney in Health and Disease Excerpt :

This volume will be a reliable source on the management of the elderly with renal disease. There is an ever-increasing proportion of the aging population affected by renal disease and hypertension, and physicians are faced with atypical clinical presentations of renal disease in the aged as compared to younger people. This volume combines the fields of nephrology and geriatrics and presents a multidisciplinary approach to the topic.

Cellular Mechanics and Biophysics Book

Cellular Mechanics and Biophysics


  • Author : Claudia Tanja Mierke
  • Publisher : Springer Nature
  • Release Date : 2020-10-30
  • Genre: Science
  • Pages : 900
  • ISBN 10 : 9783030585327

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Cellular Mechanics and Biophysics Excerpt :

This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.

Vital Dust Book

Vital Dust


  • Author : Christian De Duve
  • Publisher : Unknown
  • Release Date : 1995-01-03
  • Genre: Science
  • Pages : 362
  • ISBN 10 : UCSD:31822028296507

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Vital Dust Excerpt :

Addressing the questions of unicellular life, extraterrestrial involvement, oxygen's link to complex life, and the superior evolution of bacteria, a biochemist and winner of the Nobel Prize discusses the evolution of life on Earth. National ad/promo.

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 1990 Book

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 1990


  • Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
  • Publisher : Unknown
  • Release Date : 1989
  • Genre: United States
  • Pages : null
  • ISBN 10 : STANFORD:36105119534548

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Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 1990 Excerpt :

Lung Macrophages in Health and Disease Book

Lung Macrophages in Health and Disease


  • Author : Sandra Hodge
  • Publisher : Bentham Science Publishers
  • Release Date : 2009-09-12
  • Genre: Lungs
  • Pages : 120
  • ISBN 10 : 9781608050208

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Lung Macrophages in Health and Disease Excerpt :

"This Ebook is edited by Sandra Hodge, a recognized expert in the field of macrophage dysfunction in chronic lung disease. The book consists of 8 chapters which provide a full coverage of macrophage function in both healthy and chronically diseased lungs, "

Protein Modificomics Book

Protein Modificomics


  • Author : Tanveer Ali Dar
  • Publisher : Academic Press
  • Release Date : 2019-04-15
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 0128119136

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Protein Modificomics Excerpt :

Protein Modificomics: From Modifications to Clinical Perspectives comprehensively deals with all of the most recent aspects of post-translational modification (PTM) of proteins, including discussions on diseases involving PTMs, such as Alzheimer's, Huntington's, X-linked spinal muscular atrophy-2, aneurysmal bone cyst, angelman syndrome and OFC10. The book also discusses the role PTMs play in plant physiology and the production of medicinally important primary and secondary metabolites. The understanding of PTMs in plants helps us enhance the production of these metabolites without greatly altering the genome, providing robust eukaryotic systems for the production and isolation of desired products without considerable downstream and isolation processes. Provides thorough insights into the post translational modifications (PTMs) of proteins in both the plant and animal kingdom Presents diagrammatic representations of various protein modification and estimation mechanisms in four-color Includes coverage of diseases involving post translational modifications

Examining the Causal Relationship Between Genes  Epigenetics  and Human Health Book

Examining the Causal Relationship Between Genes Epigenetics and Human Health


  • Author : Wambuguh, Oscar J.
  • Publisher : IGI Global
  • Release Date : 2019-03-22
  • Genre: Medical
  • Pages : 603
  • ISBN 10 : 9781522580676

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Examining the Causal Relationship Between Genes Epigenetics and Human Health Excerpt :

For as much as we know about DNA and gene expression, many more mysteries remain to be solved. Epigenetics and epigenomics seek to study heritable modifications in gene expression that do not involve underlying DNA sequences to further human health changes. Examining the Causal Relationship Between Genes, Epigenetics, and Human Health provides innovative research methods and applications of chemical activation or deactivation of genes without altering the original DNA sequence. While highlighting topics including gene expression, personalized medicine, and public policy, this book is ideal for researchers, geneticists, biologists, medical professionals, students, and academics seeking current research on the expanding fields of genomics, epigenomics, proteomics, pharmacogenomics, and genome-wide association studies.

Advances in Clinical Chemistry Book

Advances in Clinical Chemistry


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2015-10-12
  • Genre: Science
  • Pages : 324
  • ISBN 10 : 9780128033159

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Advances in Clinical Chemistry Excerpt :

Advances in Clinical Chemistry, Volume 72, the latest installment in this internationally acclaimed series contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory. Contains the expertise of international contributors Provides the latest cutting-edge technologies in the field Authored by world-renowned clinical laboratory scientists, physicians, and research scientists

Glycoproteins   Advances in Research and Application  2013 Edition Book

Glycoproteins Advances in Research and Application 2013 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-06-21
  • Genre: Science
  • Pages : 261
  • ISBN 10 : 9781481688246

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Glycoproteins Advances in Research and Application 2013 Edition Excerpt :

Glycoproteins—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Protein S. The editors have built Glycoproteins—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Protein S in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Glycoproteins—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Bibliography of Medical Reviews Book

Bibliography of Medical Reviews


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1976
  • Genre: Medical literature
  • Pages : null
  • ISBN 10 : UOM:39015074112569

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Bibliography of Medical Reviews Excerpt :

Providing Healthy and Safe Foods As We Age Book

Providing Healthy and Safe Foods As We Age


  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2010-11-29
  • Genre: Medical
  • Pages : 192
  • ISBN 10 : 9780309158831

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Providing Healthy and Safe Foods As We Age Excerpt :

Does a longer life mean a healthier life? The number of adults over 65 in the United States is growing, but many may not be aware that they are at greater risk from foodborne diseases and their nutritional needs change as they age. The IOM's Food Forum held a workshop October 29-30, 2009, to discuss food safety and nutrition concerns for older adults.