Novel Therapies in Head and Neck Cancer  Beyond the Horizon Book

Novel Therapies in Head and Neck Cancer Beyond the Horizon


  • Author : Maie A. St. John
  • Publisher : Academic Press
  • Release Date : 2020-06-29
  • Genre: Science
  • Pages : 266
  • ISBN 10 : 9780128209295

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Novel Therapies in Head and Neck Cancer Beyond the Horizon Book Description :

Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers is necessary. This book discusses the outcome of recent trials using chemotherapy, novel approaches for HPV+ SCCA, cases in which immunotherapy is more likely to be successful, and precision medicine based on target therapies. Additionally, new approaches for rare diseases in head and neck and novel drug delivery platforms are presented. This book will be a very useful source so that students, scientists and clinicians who can be facile with the data, build on what is known, and continue to offer cutting-edge, validated therapies to all patients. Covers new chemotherapy trials, specifically on HPV and non-HPV related cancer types Discusses the application of immunotherapy to treat rare types of head and neck cancer Presents updated information on targeted therapies, specifically focusing on skin cancer in the region

pH Interfering Agents as Chemosensitizers in Cancer Therapy Book

pH Interfering Agents as Chemosensitizers in Cancer Therapy


  • Author : Claudiu Supuran
  • Publisher : Academic Press
  • Release Date : 2020-09-15
  • Genre: Science
  • Pages : 228
  • ISBN 10 : 9780128209288

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pH Interfering Agents as Chemosensitizers in Cancer Therapy Book Description :

pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. The continuous discovery and assessment of the role played by old/new synthetic drugs, natural compounds and technological applications has led to the urgent need of classification in terms of biological activity, mechanism of action, clinical outcomes, cancer cell lines sensible to the treatment, and potentialities to better orient research in this field. Moreover, all the aspects relevant for medicinal chemistry (drug design, structure-activity relationships, permeability data, cytotoxicity, appropriate statistical procedures, and molecular modeling studies) are strictly considered. Presents a broad view of the topic according to a medicinal chemistry-based approach beyond syntheses and biological assays, focusing on SAR studies, chemoinformatic, drug targeting and molecular modeling Explains the mechanism of action of the chemosensitizers by means of schemes and figures to facilitate comprehension Discusses novel targets to explore new possibilities that enhance research in the field

Overcoming Ovarian Cancer Chemoresistance Book

Overcoming Ovarian Cancer Chemoresistance


  • Author : Goli Samimi
  • Publisher : Academic Press
  • Release Date : 2020-11-19
  • Genre: Science
  • Pages : 188
  • ISBN 10 : 9780128198414

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Overcoming Ovarian Cancer Chemoresistance Book Description :

Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer. Provides a comprehensive view of both biological and genetic determinants of resistance, as well as technical approaches to monitor response Discusses genetic reversions as a unique alteration and a new field of study Includes a chapter on upcoming and promising agents that are in the pre-clinical and early clinical space, to set the stage for future directions in the field

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance Book

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance


  • Author : Andrew Freywald
  • Publisher : Academic Press
  • Release Date : 2020-12-04
  • Genre: Science
  • Pages : 308
  • ISBN 10 : 9780128213117

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Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance Book Description :

Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges. Provides the most updated knowledge on the mechanisms of cancer drug resistance and the emerging therapeutic approaches reviewed by experts in the field Brings detailed analyses of most important recently reported developments related to drug resistance and their relevance to overcoming it in cancer patients Discusses in-depth molecular mechanisms and novel concepts of cancer resistance to conventional and advanced therapies

Drug Efflux Pumps in Cancer Resistance Pathways  From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy Book

Drug Efflux Pumps in Cancer Resistance Pathways From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy


  • Author :
  • Publisher : Academic Press
  • Release Date : 2019-11-07
  • Genre: Business & Economics
  • Pages : 394
  • ISBN 10 : 9780128141410

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Drug Efflux Pumps in Cancer Resistance Pathways From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy Book Description :

Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance. Offers comprehensive and detailed descriptions of the basic aspects of efflux pumps in a very schematic and didactic manner Describes the involvement of efflux pumps in cancer resistance in different cancer types Encompasses an updated overview on state-of-the-art approaches that capitalize on their inhibition to improve chemotherapy and overcome resistance

Head and Neck Cancer Book
Score: 5
From 1 Ratings

Head and Neck Cancer


  • Author : John Frederick Ensley
  • Publisher : Elsevier
  • Release Date : 2003-01-07
  • Genre: Medical
  • Pages : 602
  • ISBN 10 : 0080533841

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Head and Neck Cancer Book Description :

By detailing experimental and basic research, from premalignancy to fully invasive tumors, this book has wide applicability to all human carcinomas. No other group of human cancers is better positioned for the application of recently developed novel and targeted therapies, and this book uniquely presents the unusual opportunities tumors of the head and neck provide for clinical, translational, and basic science research. Cutting-edge and experimental treatment approaches are presented, along with future strategies and an evaluation of emerging technologies. Presents a multi-disciplinary perspective from authorities in diverse fields Addresses state-of-the art approaches in cancer research as well as other scientific opportunities in this field Provides comprehensive yet easily comprehendible source of information

Beyond the Horizon  The Frontier Book

Beyond the Horizon The Frontier


  • Author : Peter Watt
  • Publisher : Pan Australia
  • Release Date : 2012-10-01
  • Genre: Fiction
  • Pages : 416
  • ISBN 10 : 9781743349649

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Beyond the Horizon The Frontier Book Description :

"the home grown version of Wilbur Smith" The Sunday Age Beyond the Horizon continues the much-loved saga of the Duffys and Macintoshes, told with Peter Watt's trademark mastery of grand scope, family drama and enthralling adventure. It is 1918, a year when the War will end, but an even greater killer will arise. On the bloody fields of the Western Front and the battle-scarred desert plains of the Middle East, Tom and Matthew Duffy are facing the enemy. Even as they are trapped on the front lines, they must also find the courage to fight for the women they love when all hope is lost. Back in Australia, George Macintosh is outraged by the stipulations of his father's will that provide for his despised nephew, and is determined to eliminate any threats to his power. And in a sacred cave in the far Outback, old Wallarie foresees a tide of unspeakable death sweeping through his homeland. As all nations come to terms with the devastating consequences of the Great War, a new world will be born. But not everyone will live to see it. PRAISE FOR THE SERIES "A rousing and revealing yarn" Weekend Australian "the historical detail brings the ... 19th century to rip-roaring life" The Australian "Watt's fans love his work for its history, adventure and storytelling" Brisbane News

DNA Alterations in Cancer Book

DNA Alterations in Cancer


  • Author : Melanie Ehrlich
  • Publisher : Eaton Publishing Company
  • Release Date : 2000
  • Genre: Medical
  • Pages : 508
  • ISBN 10 : UOM:39015049699302

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DNA Alterations in Cancer Book Description :

Head   Neck Cancer  Current Perspectives  Advances  and Challenges Book

Head Neck Cancer Current Perspectives Advances and Challenges


  • Author : James A. Radosevich
  • Publisher : Springer
  • Release Date : 2016-08-23
  • Genre: Medical
  • Pages : 1070
  • ISBN 10 : 9402400869

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Head Neck Cancer Current Perspectives Advances and Challenges Book Description :

This is a nearly complete collection of Chapters that provide an up to date overview of all aspects of Head and Neck cancer. It is written by professionals but is not only intended for other professionals, but students, patients, policy makers, etc. There are so many aspects to this group of diseases that even the most seasoned professional will learn something from having read this book.

Immunopathology and Immunomodulation Book

Immunopathology and Immunomodulation


  • Author : Krassimir Metodiev
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-11-18
  • Genre: Medical
  • Pages : 312
  • ISBN 10 : 9789535122104

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Immunopathology and Immunomodulation Book Description :

This book is a continuation of the efforts of InTech to expand the scientific know-how in the field of immunopathology and bring valuable updated information to medical professionals and researchers. It consists of chapters related to various approaches to investigate the unique role of the immune system in response to different clinical disorders. The international team of authors is the bonus of the book, reflecting the rapid development of immunology and new achievements in medical science. We firmly hope that the book will be an excellent manual and guideline for people dealing with biology, microbiology, immunology, virology, pharmacology, general and dental medicine, and health care, from students and postdocs to high-level specialists and university professors.

Multidisciplinary Care of the Head and Neck Cancer Patient Book

Multidisciplinary Care of the Head and Neck Cancer Patient


  • Author : Ellie Maghami
  • Publisher : Springer
  • Release Date : 2018-02-12
  • Genre: Medical
  • Pages : 282
  • ISBN 10 : 9783319654218

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Multidisciplinary Care of the Head and Neck Cancer Patient Book Description :

This book identifies key treatment challenges and unique care considerations in patients with head and neck cancers, providing a comprehensive guide to patient management that illustrates the critical importance of a multidisciplinary approach in achieving optimal oncological, functional, and survival outcomes. It covers all relevant specialties, including dental and oral medicine, medical oncology, radiation oncology, surgical oncology, and reconstructive surgery. It highlights the vital role played by ancillary head and neck cancer services, such as speech and swallowing therapy, occupational and physical therapy, and nutritional therapy in offering essential physical and psychological support from the time of diagnosis onward. The closing chapters address post-treatment issues, including those relating to survivorship, surveillance, and end-of-life care. Multidisciplinary care is perhaps even more important for patients with head and neck cancers than for other cancer patients, and in addressing all its aspects this book is invaluable for a wide range of practitioners.

AJCC Cancer Staging Manual Book

AJCC Cancer Staging Manual


  • Author : Frederick L, Greene
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-21
  • Genre: Medical
  • Pages : 421
  • ISBN 10 : 9781475736564

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AJCC Cancer Staging Manual Book Description :

The American Joint Committee on Cancer's Cancer Staging Manual is used by physicians throughout the world to diagnose cancer and determine the extent to which cancer has progressed. All of the TNM staging information included in this Sixth Edition is uniform between the AJCC (American Joint Committee on Cancer) and the UICC (International Union Against Cancer). In addition to the information found in the Handbook, the Manual provides standardized data forms for each anatomic site, which can be utilized as permanent patient records, enabling clinicians and cancer research scientists to maintain consistency in evaluating the efficacy of diagnosis and treatment. The CD-ROM packaged with each Manual contains printable copies of each of the book’s 45 Staging Forms.

Physics of the Future Book
Score: 3.5
From 14 Ratings

Physics of the Future


  • Author : Michio Kaku
  • Publisher : Anchor
  • Release Date : 2011-03-15
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9780385530811

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Physics of the Future Book Description :

Imagine, if you can, the world in the year 2100. In Physics of the Future, Michio Kaku—the New York Times bestselling author of Physics of the Impossible—gives us a stunning, provocative, and exhilarating vision of the coming century based on interviews with over three hundred of the world’s top scientists who are already inventing the future in their labs. The result is the most authoritative and scientifically accurate description of the revolutionary developments taking place in medicine, computers, artificial intelligence, nanotechnology, energy production, and astronautics. In all likelihood, by 2100 we will control computers via tiny brain sensors and, like magicians, move objects around with the power of our minds. Artificial intelligence will be dispersed throughout the environment, and Internet-enabled contact lenses will allow us to access the world's information base or conjure up any image we desire in the blink of an eye. Meanwhile, cars will drive themselves using GPS, and if room-temperature superconductors are discovered, vehicles will effortlessly fly on a cushion of air, coasting on powerful magnetic fields and ushering in the age of magnetism. Using molecular medicine, scientists will be able to grow almost every organ of the body and cure genetic diseases. Millions of tiny DNA sensors and nanoparticles patrolling our blood cells will silently scan our bodies for the first sign of illness, while rapid advances in genetic research will enable us to slow down or maybe even reverse the aging process, allowing human life spans to increase dramatically. In space, radically new ships—needle-sized vessels using laser propulsion—could replace the expensive chemical rockets of today and perhaps visit nearby stars. Advances in nanotechnology may lead to the fabled space elevator, which would propel humans hundreds of miles above the earth’s atmosphere at the push of a button. But these astonishing revelations are only the tip of the iceberg. Kak

Tuesdays with Morrie Book
Score: 4
From 263 Ratings

Tuesdays with Morrie


  • Author : Mitch Albom
  • Publisher : Broadway Books
  • Release Date : 2007-06-29
  • Genre: Biography & Autobiography
  • Pages : 224
  • ISBN 10 : 0307414094

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Tuesdays with Morrie Book Description :

A special 20th anniversary edition of the beloved international bestseller that changed millions of lives Maybe it was a grandparent, or a teacher, or a colleague. Someone older, patient and wise, who understood you when you were young and searching, helped you see the world as a more profound place, gave you sound advice to help you make your way through it. For Mitch Albom, that person was Morrie Schwartz, his college professor from nearly twenty years ago. Maybe, like Mitch, you lost track of this mentor as you made your way, and the insights faded, and the world seemed colder. Wouldn't you like to see that person again, ask the bigger questions that still haunt you, receive wisdom for your busy life today the way you once did when you were younger? Mitch Albom had that second chance. He reconnected with Morrie in the last months of the older man's life. Knowing he was dying, Morrie visited with Mitch in his study every Tuesday, just as they used to back in college. Their rekindled relationship turned into one final "class:" lessons in how to live. Tuesdays with Morrie is a magical chronicle of their time together, through which Mitch shares Morrie's lasting gift with the world.

Textbook of Oral Cancer Book

Textbook of Oral Cancer


  • Author : Saman Warnakulasuriya
  • Publisher : Springer Nature
  • Release Date : 2020-02-22
  • Genre: Medical
  • Pages : 452
  • ISBN 10 : 9783030323165

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Textbook of Oral Cancer Book Description :

This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.

Neurological Disorders Book
Score: 2
From 1 Ratings

Neurological Disorders


  • Author : World Health Organization
  • Publisher : World Health Organization
  • Release Date : 2006
  • Genre: Medical
  • Pages : 218
  • ISBN 10 : 9789241563369

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Neurological Disorders Book Description :

Although there are several gaps in understanding the many issues related to neurological disorders, we know enough to be able to shape effective policy responses to some of the most common. This book describes and discusses the increasing public health impact of common neurological disorders such as dementia, epilepsy, headache disorders, multiple sclerosis, neuroinfections, neurological disorders associated with malnutrition, pain associated with neurological disorders, Parkinson's disease, stroke and traumatic brain injuries. It provides information and advice on public health interventions that may reduce their occurrence and consequences, and offers health professionals and planners the opportunity to assess the burden caused by these disorders. The clear message that emerges is that unless immediate action is taken globally, the neurological burden is likely to become an increasingly serious and unmanageable.

Books in Print Book

Books in Print


  • Author :
  • Publisher :
  • Release Date : 1981
  • Genre: American literature
  • Pages :
  • ISBN 10 : STANFORD:36105124490314

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Books in Print Book Description :

Nanotheranostics for Cancer Applications Book

Nanotheranostics for Cancer Applications


  • Author : Prakash Rai
  • Publisher : Springer
  • Release Date : 2018-11-12
  • Genre: Technology & Engineering
  • Pages : 480
  • ISBN 10 : 9783030017750

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Nanotheranostics for Cancer Applications Book Description :

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

The Undying Book

The Undying


  • Author : Anne Boyer
  • Publisher : Farrar, Straus and Giroux
  • Release Date : 2019-09-17
  • Genre: Biography & Autobiography
  • Pages : 320
  • ISBN 10 : 9780374719487

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The Undying Book Description :

WINNER OF THE 2020 PULITZER PRIZE IN GENERAL NONFICTION "The Undying is a startling, urgent intervention in our discourses about sickness and health, art and science, language and literature, and mortality and death. In dissecting what she terms 'the ideological regime of cancer,' Anne Boyer has produced a profound and unforgettable document on the experience of life itself." —Sally Rooney, author of Normal People "Anne Boyer’s radically unsentimental account of cancer and the 'carcinogenosphere' obliterates cliche. By demonstrating how her utterly specific experience is also irreducibly social, she opens up new spaces for thinking and feeling together. The Undying is an outraged, beautiful, and brilliant work of embodied critique." —Ben Lerner, author of The Topeka School A week after her forty-first birthday, the acclaimed poet Anne Boyer was diagnosed with highly aggressive triple-negative breast cancer. For a single mother living paycheck to paycheck who had always been the caregiver rather than the one needing care, the catastrophic illness was both a crisis and an initiation into new ideas about mortality and the gendered politics of illness. A twenty-first-century Illness as Metaphor, as well as a harrowing memoir of survival, The Undying explores the experience of illness as mediated by digital screens, weaving in ancient Roman dream diarists, cancer hoaxers and fetishists, cancer vloggers, corporate lies, John Donne, pro-pain ”dolorists,” the ecological costs of chemotherapy, and the many little murders of capitalism. It excoriates the pharmaceutical industry and the bland hypocrisies of ”pink ribbon culture” while also diving into the long literary line of women writing about their own illnesses and ongoing deaths: Audre Lorde, Kathy Acker, Susan Sontag, and others. A genre-bending memoir in the tradition of The Argonauts, The Undying will break your heart, make you angry enough to spit, and show you contemporary America as a thing both despe