Open Source Software in Life Science Research Book

Open Source Software in Life Science Research


  • Author : Lee Harland
  • Publisher : Elsevier
  • Release Date : 2012-10-31
  • Genre: Science
  • Pages : 582
  • ISBN 10 : 9781908818249

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Open Source Software in Life Science Research Excerpt :

The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems. The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an ‘omics’ platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. Discusses a broad range of applications from a variety of sectors Provides a unique perspective on work normally performed behind closed doors Highlights the criteria used to compare and assess different approaches to solving problems

Open Source Software in Life Science Research Book

Open Source Software in Life Science Research


  • Author : L Harland
  • Publisher : Unknown
  • Release Date : 2012
  • Genre: Mathematics
  • Pages : 582
  • ISBN 10 : OCLC:1105792909

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Open Source Software in Life Science Research Excerpt :

The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems. The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. Discusses a broad range of applications from a variety of sectors Provides a unique perspective on work normally performed behind closed doors Highlights the criteria used to compare and assess different approaches to solving problems.

Encyclopedia of Bioinformatics and Computational Biology Book

Encyclopedia of Bioinformatics and Computational Biology


  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2018-08-21
  • Genre: Medical
  • Pages : 3284
  • ISBN 10 : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology Excerpt :

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

Safeguarding the Bioeconomy Book

Safeguarding the Bioeconomy


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2020-03-31
  • Genre: Science
  • Pages : 392
  • ISBN 10 : 9780309495707

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Safeguarding the Bioeconomy Excerpt :

Research and innovation in the life sciences is driving rapid growth in agriculture, biomedical science, information science and computing, energy, and other sectors of the U.S. economy. This economic activity, conceptually referred to as the bioeconomy, presents many opportunities to create jobs, improve the quality of life, and continue to drive economic growth. While the United States has been a leader in advancements in the biological sciences, other countries are also actively investing in and expanding their capabilities in this area. Maintaining competitiveness in the bioeconomy is key to maintaining the economic health and security of the United States and other nations. Safeguarding the Bioeconomy evaluates preexisting and potential approaches for assessing the value of the bioeconomy and identifies intangible assets not sufficiently captured or that are missing from U.S. assessments. This study considers strategies for safeguarding and sustaining the economic activity driven by research and innovation in the life sciences. It also presents ideas for horizon scanning mechanisms to identify new technologies, markets, and data sources that have the potential to drive future development of the bioeconomy.

Issues in Biological and Life Sciences Research  2011 Edition Book

Issues in Biological and Life Sciences Research 2011 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Genre: Science
  • Pages : 5106
  • ISBN 10 : 9781464963339

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Issues in Biological and Life Sciences Research 2011 Edition Excerpt :

Issues in Biological and Life Sciences Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Biological and Life Sciences Research. The editors have built Issues in Biological and Life Sciences Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biological and Life Sciences Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Biological and Life Sciences Research  2013 Edition Book

Issues in Biological and Life Sciences Research 2013 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-05-01
  • Genre: Science
  • Pages : 1193
  • ISBN 10 : 9781490106069

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Issues in Biological and Life Sciences Research 2013 Edition Excerpt :

Issues in Biological and Life Sciences Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Issues in Biological and Life Sciences Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biological and Life Sciences Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Funding of Biopharmaceutical Research and Development Book

The Funding of Biopharmaceutical Research and Development


  • Author : David R Williams
  • Publisher : Elsevier
  • Release Date : 2013-10-31
  • Genre: Medical
  • Pages : 284
  • ISBN 10 : 9781908818386

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The Funding of Biopharmaceutical Research and Development Excerpt :

The funding of biopharmaceutical research and development provides a comprehensive critical review of the funding of research and development (R&D) in the human biopharmaceutical market sector. It addresses both private and public funding sources available in the US and internationally. The biopharmaceutical market is among the most research-intensive market sectors globally. Clinical researchers face a multitude of public and private funding options with respect to bringing their idea or innovation to market. These funding options are continually changing and complex, and are expected to decrease in the near future. A lack of understanding of the scale, scope, and inner workings of the funding aspects of R&D can, at times, act as a barrier for all involved, and can slow down or even eliminate the R&D process. The book lessens these barriers by describing the theoretical underpinnings, present practice, and trends in R&D funding in this market sector, both in the US and internationally. This includes a review and discussion of public-private partnership activity and their inner-workings, noting the complementary relationship between public and private funding. The book also contains an overview of the inner-workings of strategic alliance activity, including the advantages and disadvantages for each party. It goes on to provide an outline of venture capital activity, detailing the methods by which venture capital firms raise capital and are organized, a description of the venture capital-entrepreneur arrangement, and the effects of this arrangement. The book also presents an overview of the IPO process and the various fates of firms going public. Presents a comprehensive view of the funding issues of R&D in this market sector, adopting a theory-to-practice approach A comprehensive and analytical review of the biopharmaceutical R&D literature and practice An overview of the various and competing/complementary theories of the firm and valuation methods as they apply to

Contaminants of Emerging Concerns and Reigning Removal Technologies Book

Contaminants of Emerging Concerns and Reigning Removal Technologies


  • Author : Manish Kumar
  • Publisher : CRC Press
  • Release Date : 2022-06-30
  • Genre: Science
  • Pages : 490
  • ISBN 10 : 9781000551044

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Contaminants of Emerging Concerns and Reigning Removal Technologies Excerpt :

With an increased demand for wastewater reuse, groundwater recharge with treated wastewater has been practiced across the globe. As a result, groundwater quality deteriorates by emerging micropollutants from various anthropogenic origins, including untreated wastewater, seepage of landfill leachate, and runoff from agricultural lands. The fate of such emerging and geogenic contaminants in subsurface systems, especially in the groundwater, depends on several factors. Physicochemical properties of contaminants such as octanol-water partition coefficient, dissociation constant, water solubility, susceptibility to biodegradation under anaerobic conditions, and environmental persistence under diverse geological and pH conditions play a critical role during subsurface mass flow. Thus, advanced wastewater treatment techniques, followed by implementing stricter guidelines, are some of the measures that can safeguard water resources. This book, in general, gives an understanding of the fate and mitigation strategies for emerging and geogenic contaminants in the groundwater. The first and second sections provide a detailed insight into various removal techniques and mitigation approaches. Possible treatment strategies, including bioremediation and natural attenuation, are also covered in those sections. Environmental assessment, groundwater vulnerability, health effects, and regulations pertaining to various contaminants are systematically presented in the third section.

NMR Metabolomics in Cancer Research Book

NMR Metabolomics in Cancer Research


  • Author : Miroslava Čuperlović-Culf
  • Publisher : Elsevier
  • Release Date : 2012-12-17
  • Genre: Medical
  • Pages : 446
  • ISBN 10 : 9781908818263

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NMR Metabolomics in Cancer Research Excerpt :

The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field. Focused description of NMR spectroscopy needed by cancer biologists who are starting to use metabolomics Current overview of knowledge related to the cancer metabolic phenotype from the perspective of metabolomics applications Information about the best practices in NMR metabolomics experimentation and data preprocessing as applied to different sample types

Bioinformatics for Biomedical Science and Clinical Applications Book

Bioinformatics for Biomedical Science and Clinical Applications


  • Author : K-H Liang
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Genre: Computers
  • Pages : 170
  • ISBN 10 : 9781908818232

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Bioinformatics for Biomedical Science and Clinical Applications Excerpt :

Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity. A coherent presentation of concepts, methodologies and practical tools that systematically lead to significant discoveries in the biomedical and clinical area Real examples of cutting edge discoveries The introduction of study types and technologies for all the DNA, RNA and protein levels

Commercializing the Stem Cell Sciences Book

Commercializing the Stem Cell Sciences


  • Author : Olivia Harvey
  • Publisher : Elsevier
  • Release Date : 2012-10-16
  • Genre: Science
  • Pages : 212
  • ISBN 10 : 9781908818140

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Commercializing the Stem Cell Sciences Excerpt :

Promising new developments in biomedical technology such as stem cell science are widely endorsed by governments keen to reduce spiralling healthcare costs, clinicians focused on patient care, and patients demanding revolutionary new treatments. Commercializing the stem cell sciences offers a comparative analysis of the commercial methods adopted in the global stem cell industries. It seeks to establish whether there is an optimum commercial model and to examine what emerging companies can learn from their predecessors. Following an introduction to stem cell sciences and the problems involved in their commercialization, the book begins with a discussion of stem cell treatments from a global perspective, and the role of innovation in the commercialization of biotechnology in general. In the second half of the book, chapters focus on the different strategies that can be employed and their relative risks and values, before a conclusion that looks at potential new developments in the field. In-depth discussion of case studies of products undergoing development Focus on commercial optimization of stem cell treatments Analysis in a global context and covering a diverse range of countries

An Introduction to Pharmaceutical Sciences Book
Score: 5
From 1 Ratings

An Introduction to Pharmaceutical Sciences


  • Author : Jiben Roy
  • Publisher : Elsevier
  • Release Date : 2011-07-25
  • Genre: Medical
  • Pages : 446
  • ISBN 10 : 9781908818041

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An Introduction to Pharmaceutical Sciences Excerpt :

This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences. This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry. A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial proces

Dictionary of Bioinformatics Book

Dictionary of Bioinformatics


  • Author : K. Manikandakumar
  • Publisher : MJP Publisher
  • Release Date : 2019-06-07
  • Genre: Computers
  • Pages : 220
  • ISBN 10 : 978186723xxxx

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Dictionary of Bioinformatics Excerpt :

Includes more than 2000 terms Covers all interdisciplinary terms Systematic flow of information Simple explanations

Issues in General Science and Scientific Theory and Method  2013 Edition Book

Issues in General Science and Scientific Theory and Method 2013 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-05-01
  • Genre: Science
  • Pages : 1201
  • ISBN 10 : 9781490109534

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Issues in General Science and Scientific Theory and Method 2013 Edition Excerpt :

Issues in General Science and Scientific Theory and Method: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Mixed Methods Research. The editors have built Issues in General Science and Scientific Theory and Method: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Mixed Methods Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in General Science and Scientific Theory and Method: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

AQUA     Life Science IP Rights on the Blockchain Frontier Book

AQUA Life Science IP Rights on the Blockchain Frontier


  • Author : Dr. Chandra Duggirala, M.D.
  • Publisher : Portal
  • Release Date : 2017-07-04
  • Genre: Computers
  • Pages : 29
  • ISBN 10 : 9780463902004

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AQUA Life Science IP Rights on the Blockchain Frontier Excerpt :

A white paper for a decentralized blockchain platform to crowdfund life sciences research & tokenize biotech intellectual property rights. v1.8 is an archived white paper, originally published in mid-2017. ABSTRACT AQUA.Foundation is reimagining intellectual property (IP) rights on the blockchain frontier, starting with life science R&D. We all understand how delays in bringing new drugs and therapies to market are costing patients’ lives, in addition to tremendous amounts of wasted research dollars. AQUA unlocks collaboration, and generates new intellectual wealth by defining, protecting and providing liquidity to IP rights. AQUA is a blockchain-powered life science R&D funding platform that accelerates breakthrough drugs and therapies to market by enabling companies to monetize their IP rights. AQUA will save millions of patients from suffering and death and billions of dollars in R&D time by providing liquidity to companies in exchange for fractional IP rights early in their lifecycle. AQUA transforms illiquid but valuable IP rights into liquid, divisible, immutable, and fractional IP rights through tradable AQUA Tokens. AQUA shortens R&D lifecycles and aligns their timelines with those of investor expectations. In this way, AQUA will unleash a Cambrian explosion in life science R&D. ABOUT AQUA Creators of the AQUA Platform have the perfect balance of Life Sciences, Entrepreneurship, Deep Technical knowledge and Crypto experience. Together, Dr. Chandra Duggirala, M.D., George Burke, and Manoj Duggirala previously founded and ran a hyper-personalized digital nutritionist/nutrition delivery startup that integrated subscribers’ digital health analytics (TryFuel.com) with DNA and other biomarkers to deliver hyper-personalized meals nationwide. They took the concept from idea through successful product development, fundraising, and market execution, building a 7-figure annual run rate (ARR) company in less than 1 year. The team envisioned the AQUA project during 2