Organic Synthesis Book

Organic Synthesis


  • Author : Michael B Smith
  • Publisher : Academic Press
  • Release Date : 2016-11-22
  • Genre: Science
  • Pages : 1106
  • ISBN 10 : 9780128008072

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Organic Synthesis Excerpt :

Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including

Organic Synthesis Book

Organic Synthesis


  • Author : Michael Smith
  • Publisher : Academic Press
  • Release Date : 2011-07-12
  • Genre: Science
  • Pages : 1536
  • ISBN 10 : 9781890661403

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Organic Synthesis Excerpt :

The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists.

Comprehensive Organic Synthesis Book

Comprehensive Organic Synthesis


  • Author : Anonim
  • Publisher : Newnes
  • Release Date : 2014-02-14
  • Genre: Science
  • Pages : 9806
  • ISBN 10 : 9780080977430

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Comprehensive Organic Synthesis Excerpt :

The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Organic Chemistry Book

Organic Chemistry


  • Author : J. David Rawn
  • Publisher : Academic Press
  • Release Date : 2018-02-03
  • Genre: Science
  • Pages : 1056
  • ISBN 10 : 9780128128398

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Organic Chemistry Excerpt :

Organic Chemistry: Structure, Mechanism, Synthesis, Second Edition, provides basic principles of this fascinating and challenging science, which lies at the interface of physical and biological sciences. Offering accessible language and engaging examples and illustrations, this valuable introduction for the in-depth chemistry course engages students and gives future and new scientists a new approach to understanding, rather than merely memorizing the key concepts underpinning this fundamental area. The book builds in a logical way from chemical bonding to resulting molecular structures, to the corresponding physical, chemical and biological properties of those molecules. The book explores how molecular structure determines reaction mechanisms, from the smallest to the largest molecules—which in turn determine strategies for organic synthesis. The book then describes the synthetic principles which extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, in which principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the theory and applications. Featuring in-book solutions and instructor PowerPoint slides, this Second Edition offers an updated and improved option for students in the two-semester course and for scientists who require a high quality introduction or refresher in the subject. Offers improvements for the two-semester course sequence and valuable updates including two new chapters on lipids and nucleic acids Features biochemistry and biological examples highlighted throughout the book, making the information relevant and engaging to readers of all backgrounds and interests Includes a valuable and highly-praised chapter on organometallic chemistry not found in other standard references

Advances in Organic Synthesis Book

Advances in Organic Synthesis


  • Author : Atta-ur-Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2011-01-10
  • Genre: Science
  • Pages : 594
  • ISBN 10 : 9781608051984

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Advances in Organic Synthesis Excerpt :

"The volume focuses on recent advances in organofluorine chemistry directed towards selective fluorine introduction into various target molecules, employing both traditional and contemporary, electrophilic and nucleophilic, fluorinating agents. It brings t"

Introduction to Strategies for Organic Synthesis Book

Introduction to Strategies for Organic Synthesis


  • Author : Laurie S. Starkey
  • Publisher : John Wiley & Sons
  • Release Date : 2012-01-18
  • Genre: Science
  • Pages : 360
  • ISBN 10 : 9781118180853

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Introduction to Strategies for Organic Synthesis Excerpt :

The stepping-stone text for students with a preliminary knowledge of organic chemistry looking to move into organic synthesis research and graduate-level coursework Organic synthesis is an advanced but important field of organic chemistry, however resources for advanced undergraduates and graduate students moving from introductory organic chemistry courses to organic synthesis research are scarce. Introduction to Strategies for Organic Synthesis is designed to fill this void, teaching practical skills for making logical retrosynthetic disconnections, while reviewing basic organic transformations, reactions, and reactivities. Divided into seven parts that include sections on Retrosynthesis and Protective Groups; Overview of Organic Transformations; Synthesis of Monofunctional Target Molecules; Synthesis of Target Molecules with Two Functional Groups; Synthesis of Aromatic Target Molecules; Synthesis of Compounds Containing Rings; and Predicting and Controlling Stereochemistry, the book covers everything students need to successfully perform retrosynthetic analyses of target molecule synthesis. Starting with a review of functional group transformations, reagents, and reaction mechanisms, the book demonstrates how to plan a synthesis, explaining functional group analysis and strategic disconnections. Incorporating a review of the organic reactions covered, it also demonstrates each reaction from a synthetic chemist's point of view, to provide students with a clearer understanding of how retrosynthetic disconnections are made. Including detailed solutions to over 300 problems, worked-through examples and end-of-chapter comprehension problems, Introduction to Strategies for Organic Synthesis serves as a stepping stone for students with an introductory knowledge of organic chemistry looking to progress to more advanced synthetic concepts and methodologies.

Principles of Organic Synthesis Book

Principles of Organic Synthesis


  • Author : Richard O.C. Norman
  • Publisher : Routledge
  • Release Date : 2017-10-19
  • Genre: Science
  • Pages : 1005
  • ISBN 10 : 9781351421720

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Principles of Organic Synthesis Excerpt :

This book is designed for those who have had no more than a brief introduction to organic chemistry and who require a broad understanding of the subject. The book is in two parts. In Part I, reaction mechanism is set in its wider context of the basic principles and concepts that underlie chemical reactions: chemical thermodynamics, structural theory, theories of reaction kinetics, mechanism itself and stereochemistry. In Part II these principles and concepts are applied to the formation of particular types of bonds, groupings, and compounds. The final chapter in Part II describes the planning and detailed execution of the multi-step syntheses of several complex, naturally occurring compounds.

Organic Synthesis Book

Organic Synthesis


  • Author : Jürgen-Hinrich Fuhrhop
  • Publisher : John Wiley & Sons
  • Release Date : 2003-03-14
  • Genre: Science
  • Pages : 546
  • ISBN 10 : 3527302727

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Organic Synthesis Excerpt :

Since it is one of the core disciplines, every student of organic chemistry will need to cover organic synthesis at some point. This third edition of an extremely well-received and proven textbook is specially written with advanced undergraduate and graduate students in mind, although it is equally useful for research chemists, too. 50% of the text is new and includes new chapters on combinatoric chemistry, non-covalent molecular assemblies and the use of the Internet for searching chemical compounds. The authors have chosen the methods included here for their efficiency, elegance, and didactic value and have highlighted important reactions within the text. From reviews of the second edition: 'The text is very readable, and the authors are especially gifted at explaining complex concepts clearly and succinctly...This book is highly recommended reading for anyone wishing to gain an overview of organic synthesis.' J. Am. Chem. Soc. With his preface, Noble prizewinner E. J. Corey has also endorsed this already highly acclaimed work.

Mechanochemical Organic Synthesis Book

Mechanochemical Organic Synthesis


  • Author : Davor Margetic
  • Publisher : Elsevier
  • Release Date : 2016-04-23
  • Genre: Science
  • Pages : 386
  • ISBN 10 : 9780128025253

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Mechanochemical Organic Synthesis Excerpt :

Mechanochemical Organic Synthesis is a comprehensive reference that not only synthesizes the current literature but also offers practical protocols that industrial and academic scientists can immediately put to use in their daily work. Increasing interest in green chemistry has led to the development of numerous environmentally-friendly methodologies for the synthesis of organic molecules of interest. Amongst the green methodologies drawing attention, mechanochemistry is emerging as a promising method to circumvent the use of toxic solvents and reagents as well as to increase energy efficiency. The development of synthetic strategies that require less, or the minimal, amount of energy to carry out a specific reaction with optimum productivity is of vital importance for large-scale industrial production. Experimental procedures at room temperature are the mildest reaction conditions (essentially required for many temperature-sensitive organic substrates as a key step in multi-step sequence reactions) and are the core of mechanochemical organic synthesis. This green synthetic method is now emerging in a very progressive manner and until now, there is no book that reviews the recent developments in this area. Features cutting-edge research in the field of mechanochemical organic synthesis for more sustainable reactions Integrates advances in green chemistry research into industrial applications and process development Focuses on designing techniques in organic synthesis directed toward mild reaction conditions Includes global coverage of mechanochemical synthetic protocols for the generation of organic compounds

New Pathways for Organic Synthesis Book

New Pathways for Organic Synthesis


  • Author : H.M. Colquhoun
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 468
  • ISBN 10 : 9781461326519

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New Pathways for Organic Synthesis Excerpt :

The continually growing contribution of transition metal chemistry to synthetic organic chemistry is, of course, widely recognized. Equally well known is the difficulty in keeping up-to-date with the multifarious reactions and procedures that seem to be spawned at an ever-increasing rate. These can certainly be summarized on the basis of reviews under the headings of the individual transition metals. More useful to the bench organic chemist, however, would be the opposite type of concordance based on the structural type of the desired synthetic product. This is the approach taken in the present monograph, which presents for each structural entity a conspectus of the transition metal-mediated processes that can be employed in its production. The resulting comparative survey should be a great help in devising the optimum synthetic approach for a particular goal. It is presented from an essentially practical viewpoint, with detailed direc tions interspersed in the Houben-Weyl style. The wide scope of the volume should certainly encourage synthetic organic chemists to utilize fully the range and versatility of these transition metal-mediated processes. This will certainly be a well-thumbed reference book! R. A. RAPHAEL Cambridge University v Preface In recent years an enormous amount of work has been done on the catalysis of organic reactions by various transition metal species and on the organic reactivity of organo-transition-metal compounds.

Handbook of Synthetic Organic Chemistry Book

Handbook of Synthetic Organic Chemistry


  • Author : Michael C. Pirrung
  • Publisher : Academic Press
  • Release Date : 2016-08-30
  • Genre: Science
  • Pages : 288
  • ISBN 10 : 9780128095041

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Handbook of Synthetic Organic Chemistry Excerpt :

Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author’s popular 2007 work, Synthetic Organic Chemist’s Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions. The book maintains the useful organization of the author’s earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product. From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process. Practical guidance for planning, working up, documenting, analyzing, and improving reactions in synthetic organic chemistry

Side Reactions in Organic Synthesis Book

Side Reactions in Organic Synthesis


  • Author : Florencio Zaragoza Dörwald
  • Publisher : John Wiley & Sons
  • Release Date : 2006-03-06
  • Genre: Science
  • Pages : 389
  • ISBN 10 : 9783527604982

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Side Reactions in Organic Synthesis Excerpt :

Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates

Organic Synthesis Book

Organic Synthesis


  • Author : Paul Wyatt
  • Publisher : John Wiley & Sons
  • Release Date : 2013-05-20
  • Genre: Science
  • Pages : 920
  • ISBN 10 : 9781118681442

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Organic Synthesis Excerpt :

Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. A comprehensive, practical account of the key concepts involved in synthesising compounds Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations Focuses on reactions that really work rather than those with limited application Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Advanced Organic Synthesis Book

Advanced Organic Synthesis


  • Author : Dmitry V. Liskin
  • Publisher : CRC Press
  • Release Date : 2015-11-04
  • Genre: Medical
  • Pages : 131
  • ISBN 10 : 9781482244977

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Advanced Organic Synthesis Excerpt :

Laboratory experience equips students with techniques that are necessary for professional practice. Advanced Organic Synthesis: A Laboratory Manual focuses on a mechanistic background of key reactions in organic chemistry, gives insight into well-established trends, and introduces new developments in the field.The book features experiments performe

Strategic Applications of Named Reactions in Organic Synthesis Book
Score: 5
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Strategic Applications of Named Reactions in Organic Synthesis


  • Author : Laszlo Kurti
  • Publisher : Elsevier
  • Release Date : 2005-04-29
  • Genre: Science
  • Pages : 864
  • ISBN 10 : 9780080575414

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Strategic Applications of Named Reactions in Organic Synthesis Excerpt :

Kurti and Czako have produced an indispensable tool for specialists and non-specialists in organic chemistry. This innovative reference work includes 250 organic reactions and their strategic use in the synthesis of complex natural and unnatural products. Reactions are thoroughly discussed in a convenient, two-page layout--using full color. Its comprehensive coverage, superb organization, quality of presentation, and wealth of references, make this a necessity for every organic chemist. * The first reference work on named reactions to present colored schemes for easier understanding * 250 frequently used named reactions are presented in a convenient two-page layout with numerous examples * An opening list of abbreviations includes both structures and chemical names * Contains more than 10,000 references grouped by seminal papers, reviews, modifications, and theoretical works * Appendices list reactions in order of discovery, group by contemporary usage, and provide additional study tools * Extensive index quickly locates information using words found in text and drawings