Organofluorine Chemistry Book

Organofluorine Chemistry


  • Author : Kenji Uneyama
  • Publisher : John Wiley & Sons
  • Release Date : 2008-04-15
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9781405172936

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Organofluorine Chemistry Excerpt :

The replacement of hydrogen with fluorine in organic molecules canprofoundly influence their chemical and physical properties,leading to a range of compounds with highly desirable properties.These molecules are of interest across the wide spectrum ofindustrial and academic organic chemistry, so that organofluorinechemistry is economically highly important. Organofluorine Chemistry will help chemists to develop a systematicknowledge of the chemistry of fluorine with a view towards itsapplication in the design of new reactions and syntheses, and thecreation of novel fluorinated molecules and materials. With initialchapters focusing on why fluorine creates such unique properties inorganic compounds, the book then covers general reactions offluorine. Coverage is chosen from the recent research literature,concentrating on the development of novel bioactive compounds andcatalytic ligands, and explaining, in the context of the initialchapters, how and why fluorine is so effective. With a finalchapter covering the general synthetic chemistry of organofluorinecompounds, the book is a cohesive summary of the fundamentalprincipals of organofluorine chemistry.

Organofluorine Chemistry Book

Organofluorine Chemistry


  • Author : V. Prakash Reddy
  • Publisher : Elsevier
  • Release Date : 2020-03-20
  • Genre: Technology & Engineering
  • Pages : 358
  • ISBN 10 : 9780128132876

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Organofluorine Chemistry Excerpt :

Organofluorine Chemistry: Synthesis and Applications gives a comprehensive outlook on modern synthetic methodologies for organofluorine compounds. It illustrates chemical, biochemical, and materials applications of fluorine-containing compounds, including synthesis and applications of small molecule compounds in drug discovery, positron emission tomography, and fluorinated polymers in solar cells. This book is of use to scientists working in the interdisciplinary areas, such as chemical, biochemical, and biomedical engineering, as well as those involved in materials science and medicinal chemistry. It is also a useful reference for researchers and graduate students interested in organofluorine chemistry. Provides modern synthetic methods and reactions of organofluorine compounds Incorporates the synthesis and chemical, biochemical and biomedical applications of fluorine-containing compounds, nanomaterials, PET imaging agents, pharmaceuticals, and polymeric materials Features emerging "hot" topics, such as late-stage fluorinations and drug discovery

Organofluorine Chemistry Book

Organofluorine Chemistry


  • Author : R.E. Banks
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-11
  • Genre: Science
  • Pages : 644
  • ISBN 10 : 9781489912022

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Organofluorine Chemistry Excerpt :

During the past fifteen years commercial interest in compounds containing carbon fluorine bonds has burgeoned beyond all expectations, mainly owing to business opportunities arising from work on biologically active fluoroorganics-particularly agrochemicals, the relentless search for new markets for fluoropolymers and fluoro carbon fluids, developments in the field of medical diagnostics, and the drive to find replacements for ozone-depleting CFCs and Halon fire-extinguishing agents. Judging the situation to warrant the publication of a comprehensive collection of up-to-date reviews dealing with commercial organofluorine compounds within a single volume of manageable size (and hence reasonable cost), we were delighted to be invited by Plenum Publishing Corporation to produce a suitable book. In order to provide an authentic and wide-ranging account of current commercial applications of fluoroorganic materials, it clearly was necessary to assemble a sizeable team of knowledgeable contributing authors selected almost entirely from industry. Through their efforts we have been able to produce an almost complete coverage of the modem organofluorochemicals business in a manner designed to attract a reader ship ranging from experts in the field, through chemists and technologists currently unaware of the extent of industrial involvement with fluoroorganics, to students of applied chemistry. Promised chapters dedicated to perfluoroolefin oxides and 18F labeling of radiopharmaceuticals failed to materialize. This is somewhat unfortunate in view of our aim to achieve comprehensive coverage of the subject.

Organofluorine Chemistry Book

Organofluorine Chemistry


  • Author : Kalman J. Szabo
  • Publisher : John Wiley & Sons
  • Release Date : 2021-03-22
  • Genre: Science
  • Pages : 464
  • ISBN 10 : 9783527347117

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Organofluorine Chemistry Excerpt :

By presenting novel methods for the efficient preparation of fluorinated compounds and their application in pharmaceutical and agrochemical chemistry as well as medicine, this is a valuable source of information for all researchers in academia and industry!

Organofluorine Compounds in Biology and Medicine Book

Organofluorine Compounds in Biology and Medicine


  • Author : V Prakash Reddy
  • Publisher : Newnes
  • Release Date : 2015-01-25
  • Genre: Science
  • Pages : 330
  • ISBN 10 : 9780444537492

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Organofluorine Compounds in Biology and Medicine Excerpt :

This book covers topics on biochemically relevant organofluorine compounds and their synthesis and biochemical pathways. Organofluorine compounds have renewed interest in pharmaceutical industry, and therefore a concise book on this topic is highly relevant to the scientific community involved in this area. Covers the synthesis, biochemical, and therapeutic applications of organofluorine compounds Offers a complete text on biochemically relevant organofluorine compounds and their synthesis and mechanistic pathways Provides one of the first major reference books on the biological and medicinal applications of organofluorine chemistry

Organofluorine Compounds Book

Organofluorine Compounds


  • Author : Tamejiro Hiyama
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-09
  • Genre: Science
  • Pages : 272
  • ISBN 10 : 9783662041642

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Organofluorine Compounds Excerpt :

In view of increasing interest in organofluorine compounds, this book was undertaken to describe biological and physical properties of organofluorine compounds, synthetic methods of these, their roles in pharmaceutical, agrochemical and material sciences. In particular, the book will emphasize on the usefulness of fluorination reaction, availability of fluorination agents, so that even graduate students who are unfamiliar to this field can understand and participate in this fascinating heteroatom chemistry.

Frontiers Of Organofluorine Chemistry Book

Frontiers Of Organofluorine Chemistry


  • Author : Iwao Ojima
  • Publisher : World Scientific
  • Release Date : 2019-12-24
  • Genre: Science
  • Pages : 844
  • ISBN 10 : 9781786347343

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Frontiers Of Organofluorine Chemistry Excerpt :

This book focuses on the new frontiers of organofluorine chemistry in synthetic, organometallic, bioorganic, medicinal, agricultural, and materials chemistry as well as chemical physics and their applications to biomedical and material sciences. The extraordinary potential of fluorine-containing molecules in biology, pharmaceuticals, agrochemical, materials and their wide range of applications has been recognized by researchers who are not in the traditional fluorine chemistry field, and thus the new wave of organofluorine chemistry is rapidly expanding its frontiers.Featuring major leading researchers from all over the world and their cutting-edge research projects, this title reviews the recent advances and envision the new exciting developments in the future. Frontiers of Organofluorine Chemistry is an excellent reference book for professional researchers, and graduate students, in both industry and academia to get inspirations and new ideas for their projects.

Modern Fluoroorganic Chemistry Book

Modern Fluoroorganic Chemistry


  • Author : Peer Kirsch
  • Publisher : John Wiley & Sons
  • Release Date : 2006-03-06
  • Genre: Science
  • Pages : 320
  • ISBN 10 : 9783527604197

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Modern Fluoroorganic Chemistry Excerpt :

In this handbook, Peer Kirsch clearly shows that this exciting field is no longer an exotic area of research. Aimed primarily at synthetic chemists wanting to gain a deeper understanding of the fascinating implications of including the highly unusual element fluorine in organic compounds, the main part of the book presents a wide range of synthetic methodologies and the experimental procedures selected undeniably show that this can be done with standard laboratory equipment. To round off, the author looks at fluorous chemistry and the applications of organofluorine compounds in liquid crystals, polymers and more besides. This long-awaited book represents an indispensable source of high quality information for everyone working in the field.

Fluorine in Organic Chemistry Book
Score: 4
From 1 Ratings

Fluorine in Organic Chemistry


  • Author : Richard D. Chambers
  • Publisher : CRC Press
  • Release Date : 2004
  • Genre: Science
  • Pages : 406
  • ISBN 10 : 0849317908

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Fluorine in Organic Chemistry Excerpt :

The introduction of carbon-fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine-containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties. This book covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems.

Organofluorine Chemistry Book

Organofluorine Chemistry


  • Author : B. Ameduri
  • Publisher : Springer Science & Business Media
  • Release Date : 1997-09-18
  • Genre: Science
  • Pages : 244
  • ISBN 10 : 3540631712

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Organofluorine Chemistry Excerpt :

The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.

Organofluorine Chemistry Book

Organofluorine Chemistry


  • Author : Richard D. Chambers
  • Publisher : Springer
  • Release Date : 2003-09-05
  • Genre: Science
  • Pages : 252
  • ISBN 10 : 9783540691976

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Organofluorine Chemistry Excerpt :

The excitement of the chemistry of organofluorine compounds stems from the unique reactions that arise and the "special effects" that introduction of fluorine impart on a molecule. Indeed, these effects are now exploited in a remarkable array of applications the whole of the chemical, pharmaceutical, and plant-protection industries. In this two-volume set, we have gathered authors with immense experience in various aspects of their fields and each is a world-authority on the important topics which they have described. The first volume treats the chemistry of fluorinated alkenes, which are important "building-blocks" for the synthesis of a range of fluorinated systems and are used widely in industry. The second volume is directed to techniques and synthons for obtaining fluorinated compounds.

Fluorine and Health Book

Fluorine and Health


  • Author : Alain Tressaud
  • Publisher : Elsevier
  • Release Date : 2008-06-06
  • Genre: Medical
  • Pages : 816
  • ISBN 10 : 0080558119

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Fluorine and Health Excerpt :

Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms. Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds

Fluorine Chemistry Book

Fluorine Chemistry


  • Author : J.H. Simons
  • Publisher : Elsevier
  • Release Date : 2012-12-02
  • Genre: Science
  • Pages : 252
  • ISBN 10 : 9780323158954

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Fluorine Chemistry Excerpt :

Fluorine Chemistry, Volume III: Biological Effects of Organic Fluorides focuses on the biological threats of fluorine-containing compounds. The book first looks at the toxicity of fluoroacetate. Acute human poisoning, chemical factors, cause of death, pharmacological properties, evidence of fluorocitrate, and sites of inhibition are discussed. The text notes the biological effects of phosphofluoridates. Toxicity of DFP and derivatives, DFP metabolism, studies on DFP32 metabolism, and enzymes hydrolyzing DFP are described. The book also looks at the effects of acute doses of fluorine-containing organic compounds. The effects of organic fluorine compounds on enzyme systems; metabolic effects of tyrosine analogs; local anesthetics; effects of organofluorine compounds on microorganisms; and miscellaneous pharmacological effects of organic fluorides are discussed. The text underscores the acute effects of organofluorine compounds in experimental animals. Tabulated representations that show the effects of fluorine-containing compounds on humans and animals are presented. The book is a valuable source of information for readers wanting to study the biological effects of fluorine-containing compounds.

Emerging Fluorinated Motifs  2 Volume Set Book

Emerging Fluorinated Motifs 2 Volume Set


  • Author : Dominique Cahard
  • Publisher : John Wiley & Sons
  • Release Date : 2020-05-26
  • Genre: Science
  • Pages : 760
  • ISBN 10 : 9783527346813

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Emerging Fluorinated Motifs 2 Volume Set Excerpt :

A must-have resource for all the researchers working in the organofluorine and related fields This timely two-volume set uniquely focuses on emerging fluorinated motifs beyond R-CF3 and R-F, like R-CF2H, R-OCF3, R-SCF3 and R-SF5. It also offers descriptions of the properties, synthesis, and applications of these emerging fluorinated motifs in order to help readers design new chemical entities, while providing new interest for researchers in organofluorine chemistry and new tools for those in other areas. Emerging Fluorinated Motifs: Synthesis, Properties and Applications begins with a description of carbon-linked fluorine-containing groups that include monofluoromethyl and difluoromethyl groups. It then details combinations of heteroatoms, Oxygen, Sulfur, Selenium, Nitrogen, and Phosphorus with fluorine-containing groups, outlining subsections of the most popular current motifs. Fluoroalkyl ethers, thioethers, and the recent blossoming of the SF5 unit is covered. Other chapters look at: selenium-linked fluorine-containing motifs; construction of N?CF2H, N?CF3, N?CH2CF3 motifs; and the synthesis and applications of P¿Rf-containing molecules. -Focuses on the synthesis, properties, and applications of emerging fluorinated motifs -Covers carbon-linked fluorine-containing motifs, oxygen-linked fluorine-containing motifs, sulfur-linked fluorine-containing motifs, and more -Appeals to academic and industrial researchers working in organic chemistry, medicinal chemistry, food chemistry, and materials science -Edited by world-renowned experts in organofluorine chemistry Emerging Fluorinated Motifs is intended for academic research institutes, university libraries, researchers, graduate students, postdoctors, and researchers in the chemical industry.

Advances in Organic Synthesis Book

Advances in Organic Synthesis


  • Author : Atta-ur-Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2013-01-10
  • Genre: Science
  • Pages : 480
  • ISBN 10 : 9781608054756

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Advances in Organic Synthesis Excerpt :

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in the academia and industry who wish to keep abreast of rapid and important developments in the field.