Pathogenesis  Treatment and Prevention of Leishmaniasis Book

Pathogenesis Treatment and Prevention of Leishmaniasis

  • Author : Mukesh Samant
  • Publisher : Academic Press
  • Release Date : 2021-08-18
  • Genre: Medical
  • Pages : 280
  • ISBN 10 : 9780128227985

Pathogenesis Treatment and Prevention of Leishmaniasis Excerpt :

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment Discusses novel approaches to study parasite infection and treatment Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies

Pathogenesis of Leishmaniasis Book

Pathogenesis of Leishmaniasis

  • Author : Abhay Satoskar
  • Publisher : Springer
  • Release Date : 2016-08-23
  • Genre: Medical
  • Pages : 93
  • ISBN 10 : 1493945327

Pathogenesis of Leishmaniasis Excerpt :

This book discusses recent developments in several laboratories studying leishmaniasis. Sequencing of the human genome, as well as of the leishmania genome, has led to significant advances in our understanding of host-immune responses against leishmania, and mechanisms of infection-induced pathology, which is responsible for morbidity and mortality. Pathogenesis of Leishmaniasis focuses on the latest basic research into leishmaniasis, but also addresses how advances in understanding can be applied to prevention, control and treatment of what the WHO has classified a neglected tropical disease.

Drug Discovery for Leishmaniasis Book

Drug Discovery for Leishmaniasis

  • Author : Carmen Gil
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-11-02
  • Genre: Science
  • Pages : 422
  • ISBN 10 : 9781782628897

Drug Discovery for Leishmaniasis Excerpt :

For human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides. Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania. Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.

Leishmaniasis Book


  • Author : David Claborn
  • Publisher : BoD – Books on Demand
  • Release Date : 2014-03-19
  • Genre: Medical
  • Pages : 538
  • ISBN 10 : 9789535112327

Leishmaniasis Excerpt :

Of all the parasitic diseases, leishmaniasis is one of the most diverse, with a variety of manifestations, from relatively minor cutaneous lesions to deadly visceral infections. It is also widespread, causing human disease in the Americas, Asia, Europe and Africa. The environments in which this disease occurs range from desert to tropical jungle to urban habitats. Not surprisingly, the literature on this disease is written in a variety of languages including Portuguese, Arabic, English and French among others. This book provides a synopsis in English of much of the recent research on leishmaniasis, with a focus on the epidemiology, diagnosis and treatment of the disease as described by researchers around the world, but with a focus on the research from Brazil and the Middle East.

Canine Medicine Book

Canine Medicine

  • Author : Hussein Abdelhay Essayed Kaoud
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-12-21
  • Genre: Science
  • Pages : 215
  • ISBN 10 : 9789535128311

Canine Medicine Excerpt :

There is a possibility that during a pet's lifetime, medication may be recommended to treat medical conditions or problems. This book Canine Medicine - Recent Topics and Advanced Research provides the knowledge in diagnosis and treatment of some important diseases and problems that the canines face. I believe that this book offers broader perspective to the readers in the recent advances in canine medicine, starting from recent topics to application in clinical diagnosis and therapeutics for practitioners and veterinarians. The main purpose of the book is to point out the interest of some important topics of canine medicine and the progress in this field and to clear its importance in veterinary medicine.

Tropical Dermatology Book

Tropical Dermatology

  • Author : Roberto Arenas
  • Publisher : CRC Press
  • Release Date : 2001-01-01
  • Genre: Science
  • Pages : 358
  • ISBN 10 : 9781498712750

Tropical Dermatology Excerpt :

Tropical diseases are not merely a group of nosologic diseases indigenous to the intertropical zone. Many are diseases of poor public health originating from poverty, ignorance, and population upheaval. Tropical dermatoses represent a public health problem in 127 countries with a population of 3 billion people who do not have access to health care.

Hunter s Tropical Medicine and Emerging Infectious Diseases E Book Book

Hunter s Tropical Medicine and Emerging Infectious Diseases E Book

  • Author : Edward T Ryan
  • Publisher : Elsevier Health Sciences
  • Release Date : 2019-03-25
  • Genre: Medical
  • Pages : 1264
  • ISBN 10 : 9780323625500

Hunter s Tropical Medicine and Emerging Infectious Diseases E Book Excerpt :

New emerging diseases, new diagnostic modalities for resource-poor settings, new vaccine schedules ... all significant, recent developments in the fast-changing field of tropical medicine. Hunter’s Tropical Medicine and Emerging Infectious Diseases, 10th Edition, keeps you up to date with everything from infectious diseases and environmental issues through poisoning and toxicology, animal injuries, and nutritional and micronutrient deficiencies that result from traveling to tropical or subtropical regions. This comprehensive resource provides authoritative clinical guidance, useful statistics, and chapters covering organs, skills, and services, as well as traditional pathogen-based content. You’ll get a full understanding of how to recognize and treat these unique health issues, no matter how widespread or difficult to control. Includes important updates on malaria, leishmaniasis, tuberculosis and HIV, as well as coverage of Ebola, Zika virus, Chikungunya, and other emerging pathogens. Provides new vaccine schedules and information on implementation. Features five all-new chapters: Neglected Tropical Diseases: Public Health Control Programs and Mass Drug Administration; Health System and Health Care Delivery; Zika; Medical Entomology; and Vector Control – as well as 250 new images throughout. Presents the common characteristics and methods of transmission for each tropical disease, as well as the applicable diagnosis, treatment, control, and disease prevention techniques. Contains skills-based chapters such as dentistry, neonatal pediatrics and ICMI, and surgery in the tropics, and service-based chapters such as transfusion in resource-poor settings, microbiology, and imaging. Discusses maladies such as delusional parasitosis that are often seen in returning travelers, including those making international adoptions, transplant patients, medical tourists, and more.

Parasitology and Microbiology Research Book

Parasitology and Microbiology Research

  • Author : Gilberto Antonio Bastidas Pacheco
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-06-17
  • Genre: Medical
  • Pages : 376
  • ISBN 10 : 9781789859010

Parasitology and Microbiology Research Excerpt :

The study of both unicellular and multicellular living beings and the diseases they produce from a biological point of view requires constant review of their relationship with their host and environment, given their indisputable sanitary importance. In this sense, in parasitology and microbiology, updated and concise information on life cycle, taxonomic classification, clinical manifestations, diagnosis, treatment, epidemiological behavior, and control measures is of vital importance. This is what we pursue with this book. The approach to parasitology and microbiology and the research that is carried out on it is unquestionable because the associations between life forms have been present from the very beginning of life.Research in parasitology and microbiology is necessary and indispensable for controlling diseases that affect much of the world with serious economic and social consequences. The challenge is to promote research to keep these diseases at bay. This book shows what has been done up to now and what can be done in the future to combat infectious diseases.

Immunopathology  Diagnosis and Treatment of HPV induced Malignancies Book

Immunopathology Diagnosis and Treatment of HPV induced Malignancies

  • Author : Prashant Khare
  • Publisher : Academic Press
  • Release Date : 2022-08-12
  • Genre: Medical
  • Pages : 224
  • ISBN 10 : 9780323986441

Immunopathology Diagnosis and Treatment of HPV induced Malignancies Excerpt :

Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies. Highlights the concept of Human papilloma virus infection, its pathogenesis, mechanisms involved in host immune response, clinical manifestations, prophylactic and therapeutic strategies, and recent advancements for the cure of HPV induced cancer Delineates new insights and challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancer Provides comprehensive and conceptual knowledge that could be a milestone not only in the field of infectious cancers but also for researchers and scientists working on infectious cancer

Drug Resistance in Leishmania Parasites Book

Drug Resistance in Leishmania Parasites

  • Author : Alicia Ponte-Sucre
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-09-04
  • Genre: Medical
  • Pages : 462
  • ISBN 10 : 9783709111253

Drug Resistance in Leishmania Parasites Excerpt :

One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.

Field Trials of Health Interventions Book

Field Trials of Health Interventions

  • Author : Peter G. Smith
  • Publisher : Oxford University Press, USA
  • Release Date : 2015
  • Genre: Medical
  • Pages : 479
  • ISBN 10 : 9780198732860

Field Trials of Health Interventions Excerpt :

"IEA, International Epidemiological Association, Welcome Trust."

Leishmaniases as Re emerging Diseases Book

Leishmaniases as Re emerging Diseases

  • Author : Farhat Afrin
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-10-10
  • Genre: Medical
  • Pages : 234
  • ISBN 10 : 9781789841015

Leishmaniases as Re emerging Diseases Excerpt :

Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.

Viral  Parasitic  Bacterial  and Fungal Infections Book

Viral Parasitic Bacterial and Fungal Infections

  • Author : Debasis Bagchi
  • Publisher : Academic Press
  • Release Date : 2022-10-15
  • Genre: Medical
  • Pages : 980
  • ISBN 10 : 9780323898003

Viral Parasitic Bacterial and Fungal Infections Excerpt :

Viral, Parasitic, Bacterial, and Fungal Infections: Antimicrobial, Host Defense, and Therapeutic Strategies highlight diverse types of infections, including viral, bacterial, parasitic, fungal, and the therapeutic efficacy of antibiotics, antivirals, antifungals and other medications, nutraceuticals, and phytotherapeutics. This book addresses the molecular, pathophysiological, and cellular pathways involved in the process of infection. It also examines the host defense mechanisms modulated by innate and adaptive immunity. The book starts off with an introduction, which includes etiology, pathophysiology, and diagnosis of infections. It then goes on to cover a wide spectrum of salient features involved in viral, bacterial, parasitic, and fungal infections and effective therapeutic strategies. In addition, there is a complete section of eight chapters elaborating the detailed aspects of COVID-19 infections, Mucormycosis, Omicron, and strategic vaccines and therapeutics. The book further goes on to discuss novel antibiotics, vaccines, bromhexine, boron compounds, phytotherapeutics, and aspects on boosting immune competence. Contributed by experts in the fields of viral, parasitic, bacterial, and fungal infections, the book comprehensively details the various types of infections such as herpes and COVID-19, their molecular mechanisms, and treatment strategies for those engaged in the research of infectious diseases. • Details the pathophysiology of various classes of infections • Examines mechanisms of pathogenesis, immunity, and therapeutics in bacterial, viral, and eukaryotic infectious diseases • Discusses various aspects on herpes, COVID-19 infections, Mucormycosis, Omicron, vaccines, and therapeutics • Covers the salient features on zoonosis, prion disease, and diabetic foot infections • Provides therapeutic strategies of using new antibiotics, vaccines, bromhexine, boron compounds, structurally diverse phytotherapeutics, immune enhancers, and other modal

Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis Book

Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis

  • Author : World Health Organization
  • Publisher : Unknown
  • Release Date : 2012
  • Genre: Electronic books
  • Pages : 0
  • ISBN 10 : 9240689990

Research Priorities for Chagas Disease Human African Trypanosomiasis and Leishmaniasis Excerpt :

The Disease Reference Group on Chagas Disease Human AfricanTrypanosomiasis and Leishmaniasis (DRG3) was part of an independent thinktankof international experts established by the Special Programme for Researchand Training in Tropical Diseases (TDR) to identify key research prioritiesthrough systematic review of research evidence and input from stakeholders. These three distinct insect-borne diseases while caused by related kinetoplastidprotozoan pathogens have dissimilar geographical distributions a reflection oftheir different insect vectors and range of vector contact with humans. Thedisease.

CDC Yellow Book 2018  Health Information for International Travel Book

CDC Yellow Book 2018 Health Information for International Travel

  • Author : Centers for Disease Control and Prevention CDC
  • Publisher : Oxford University Press
  • Release Date : 2017-04-17
  • Genre: Medical
  • Pages : 672
  • ISBN 10 : 9780190628635

CDC Yellow Book 2018 Health Information for International Travel Excerpt :

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.