Pediatric Cancer Genetics Book

Pediatric Cancer Genetics


  • Author : Nathaniel H. Robin
  • Publisher : Elsevier Health Sciences
  • Release Date : 2017-08-22
  • Genre: Medical
  • Pages : 350
  • ISBN 10 : 9780323495967

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Pediatric Cancer Genetics Excerpt :

Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

The Hereditary Basis of Childhood Cancer Book

The Hereditary Basis of Childhood Cancer


  • Author : David Malkin
  • Publisher : Springer Nature
  • Release Date : 2021-09-06
  • Genre: Medical
  • Pages : 491
  • ISBN 10 : 9783030744489

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The Hereditary Basis of Childhood Cancer Excerpt :

This volume elaborates on the research and clinical implications of the hereditary and molecular basis of childhood cancers. The focus of the ‘disease-related’ chapters of the book is to integrate what is known about the molecular basis of that particular clinical entity (or group of related entities) with the clinical manifestations, to relate the relationship of the molecular oncologic pathways with relevant developmental or non-human species biology in order to better understand the complexity of these systems. The resulting clinical implications of understanding this biology are elaborated on. Chapters 13-16 discuss the broader psychosocial, ethical and genetic counseling issues that arise and that are so critical to translating the knowledge gained from advances in molecular genetics into the clinic. Chapter 12 in particular provides a unique perspective of the application of this knowledge in less-developed nations where ‘modern’ technologies may not be readily available, but where the clinical manifestations of these disorders are prevalent.

Pediatric Cancer Genetics Book

Pediatric Cancer Genetics


  • Author : Nathaniel H. Robin
  • Publisher : Unknown
  • Release Date : 2017-09-28
  • Genre: Medical
  • Pages : 350
  • ISBN 10 : 0323485553

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Pediatric Cancer Genetics Excerpt :

Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today's available information and guidance in this timely area into one convenient resource.

The Genetics of Cancer Book

The Genetics of Cancer


  • Author : B.A. Ponder
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Medical
  • Pages : 221
  • ISBN 10 : 9789401106771

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The Genetics of Cancer Excerpt :

It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proved to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result. The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.

Hereditary Colorectal Cancer Book

Hereditary Colorectal Cancer


  • Author : Laura Valle
  • Publisher : Springer
  • Release Date : 2018-05-04
  • Genre: Medical
  • Pages : 505
  • ISBN 10 : 9783319742595

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Hereditary Colorectal Cancer Excerpt :

This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.

Cancer Genomics Book

Cancer Genomics


  • Author : Graham Dellaire
  • Publisher : Academic Press
  • Release Date : 2013-11-21
  • Genre: Medical
  • Pages : 510
  • ISBN 10 : 9780123972743

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Cancer Genomics Excerpt :

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment. Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics. Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.

Accomplishments  Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition Book

Accomplishments Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition


  • Author : Paolo Peterlongo
  • Publisher : Frontiers Media SA
  • Release Date : 2019-10-16
  • Genre: Uncategoriezed
  • Pages : 141
  • ISBN 10 : 9782889631322

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Accomplishments Collaborative Projects and Future Initiatives in Breast Cancer Genetic Predisposition Excerpt :

In this eBook, we described the accomplishments, collaborative projects and future initiatives in the field of breast cancer genetic predisposition. More specifically, the articles included focused on aspects such as mutation screening in unexplored populations, identification and characterization of novel predisposing genes and mutations, and population screening.

Principles of Clinical Cancer Genetics Book

Principles of Clinical Cancer Genetics


  • Author : Daniel C. Chung
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-07-20
  • Genre: Medical
  • Pages : 227
  • ISBN 10 : 9780387938462

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Principles of Clinical Cancer Genetics Excerpt :

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Cancer Genetics  A Clinical Approach Book

Cancer Genetics A Clinical Approach


  • Author : Xavier Llor
  • Publisher : McGraw Hill Professional
  • Release Date : 2021-11-19
  • Genre: Medical
  • Pages : 512
  • ISBN 10 : 9781260440287

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Cancer Genetics A Clinical Approach Excerpt :

The ultimate guide to caring for and communicating with patients suffering with hereditary cancer syndromes Providing the essential tools needed to understand clinical cancer genetics, Cancer Genetics: A Clinical Approach builds your mastery of differential diagnosis formulation, all the available genetic testing options at your disposal, interpreting results logically and accurately, and educating patients and their families about effective cancer prevention methods. This unparalleled resource walks you through the process of effectively and thoughtfully counseling patients—from pre-test counseling and relaying test results to navigating the legal implications of hereditary conditions and coping with the resulting psychological challenges. Cancer Genetics: A Clinical Approach is ideal for both specialized cancer genetics clinics or any healthcare professional seeking to improve their skills in identifying patients with possible hereditary cancer syndromes and recognizing which ones should be referred to a high-risk/clinical genetics specialty program.

Pediatric Neuro oncology Book

Pediatric Neuro oncology


  • Author : Katrin Scheinemann
  • Publisher : Springer
  • Release Date : 2015-03-26
  • Genre: Medical
  • Pages : 318
  • ISBN 10 : 9781493915415

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Pediatric Neuro oncology Excerpt :

“The editors...have done an outstanding job of presenting...complex information in a lucid manner – this book is a must-read for the global community of aspiring students and neuro-oncology practitioners.” Amar Gajjar, MD in the Foreword This is a succinct introduction to pediatric neuro-oncology. It summarizes the key advances in molecular biology that have helped transform this rapidly evolving field and provides up-to-date coverage of major and emerging treatment modalities as well as supportive care. Separate chapters present each kind of pediatric brain cancer and its diagnosis and treatment. As more children survive brain cancer, the importance of quality of life issues and helping survivors to cope with the neuropsychological impact and long-term effects of current therapies has come into sharper focus; these topics are also addressed in the book, as are palliative care and pediatric neuro-oncology in countries with limited resources. The book is aimed at trainees and practitioners who seek an up-to-date text in pediatric neuro-oncology that is both comprehensive and concise.

Principles and Practice of Pediatric Oncology Book

Principles and Practice of Pediatric Oncology


  • Author : Philip A. Pizzo
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2015-06-24
  • Genre: Medical
  • Pages : 5113
  • ISBN 10 : 9781496318763

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Principles and Practice of Pediatric Oncology Excerpt :

Now thoroughly updated to include new advances in the field,and with regular content updates to the eBook, Principles and Practice of Pediatric Oncology, 7th Edition remains the gold standard text for the care and research of children with cancer. This authoritative reference is the single most comprehensive resource on the biology and genetics of childhood cancer and the diagnosis, multimodal treatment, and long-term management of young patients with cancer. Also addressed are a broad array of topics on the supportive and psychosocial aspects of care of children and families. Covering virtually every aspect of the breadth and depth of childhood cancer, this 7th Edition provides expert guidance on state-of-the-art, multidisciplinary care for children and families. Stay up to date with the most recent advances in the field with the contributions by new and returning contributors, including the perspective from patients and parents in the chapter titled “The Other Side of the Bed.” Reference your eBook version for key updates in the field during the life of the edition! Chapters included on palliative care and education. Supportive care is covered broadly and specifically – in contexts such as emergencies, infectious disease, and nutrition. The most updated and authoritative information is provided by the leading experts in the field. Gain a thorough understanding of every aspect of pediatric oncology, with comprehensive information regarding basic science, diagnostic tools, principles of treatment, and clinical trials, as well as highly detailed, definitive coverage of each pediatric malignancy. Collaborate more effectively with others on the cancer care team to enhance quality-of-life issues for patients and families. Understand the cooperative nature of pediatric oncology as a model for cancer research with information from cooperative clinical trial groups and consortia.

Anticipate and Communicate Book

Anticipate and Communicate


  • Author : Presidential Commission for the Study of Bioethical Issues
  • Publisher : CreateSpace
  • Release Date : 2015-03-11
  • Genre: Medical
  • Pages : 156
  • ISBN 10 : 1508807647

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Anticipate and Communicate Excerpt :

Anticipate and Communicate is the Bioethics Commission's sixth major report. In this report the Bioethics Commission offers specific recommendations for the management of incidental and secondary findings in clinical, research and direct-to-consumer settings. Emerging medical technologies, changing cost structures, and evolving medical practice make the likelihood of discovering incidental and secondary findings across contexts a growing certainty. Such findings can be lifesaving, but also can lead to uncertainty and distress if they are unexpected or identify conditions for which no effective treatment is available.

Pediatric Oncology Nursing Book

Pediatric Oncology Nursing


  • Author : Pamela S. Hinds
  • Publisher : Springer Nature
  • Release Date : 2020-01-23
  • Genre: Medical
  • Pages : 348
  • ISBN 10 : 9783030258047

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Pediatric Oncology Nursing Excerpt :

This book presents the current state of the nursing science in topics relevant to the care of pediatric oncology patients and their families across the treatment trajectory and is framed within a precision health framework. The spectrum of topics covered is wide, including, for example, symptom management, self-care management, exercise and physical activity, family-centered care, palliative care, the role of the nurse in treatment decision making, patient and nurse resiliency, survivorship, and genetic counseling. Throughout, there is a focus on the implications of research for nursing practice, highlighting which elements of the available evidence are ready for translation into practice and which are not. In addition, careful attention is paid to the role that nursing can play in further advancing science through clinical research. The authors are leading experts from across the globe. The book will be of special interest for pediatric oncology nurses, including direct care nurses, research nurses, and nursing leaders, and will also be a stimulating source for researchers and non-oncology nurses.

Pediatric Hematology and Oncology Book

Pediatric Hematology and Oncology


  • Author : Edward Estlin
  • Publisher : John Wiley & Sons
  • Release Date : 2011-07-20
  • Genre: Medical
  • Pages : 442
  • ISBN 10 : 9781444322552

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Pediatric Hematology and Oncology Excerpt :

This new textbook has an international authorship and is a practical, up-to-date resource for clinicians responsible for the care of children with oncologic and malignant hematologic disease. It is specifically designed for practicing oncologists and hematologists, pediatricians with an interest in childhood cancer and trainees seeking a systematic approach to these disorders. This new textbook has an emphasis on the visual presentation and ease of reading of contemporary and comprehensive information for children’s cancers and contains detailed tables, fact boxes and illustrations. The textbook begins with an introduction to the general principles of the scientific foundation and treatment of childhood cancers and hematological malignancies. Separate sections are then devoted to descriptions of central nervous system tumors, hematological malignancies and solid tumors of childhood which encompass epidemiology, cellular and molecular biology, cancer genetics, immunology, pharmacology and the findings of clinical trials. For each area of science covered, key original references and reviews are highlighted to direct further reading. Diagnostic, biological, and therapeutic issues are integrated into each tumor-specific chapter, with evidence supporting the current rationales for risk stratification and the development of novel therapies. A final section then explores supportive care, palliative care, late effects considerations and psychosocial issues as relate to children’s cancer.

Genetic Predisposition to Cancer Book
Score: 3.5
From 2 Ratings

Genetic Predisposition to Cancer


  • Author : Rosalind A. Eeles
  • Publisher : Springer
  • Release Date : 2013-11-11
  • Genre: Medical
  • Pages : 407
  • ISBN 10 : 9781489945013

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Genetic Predisposition to Cancer Excerpt :