Practical Approaches to Biological Inorganic Chemistry Book

Practical Approaches to Biological Inorganic Chemistry


  • Author : Robert R. Crichton
  • Publisher : Newnes
  • Release Date : 2012-12-31
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780444563590

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Practical Approaches to Biological Inorganic Chemistry Excerpt :

The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures

Practical Approaches to Biological Inorganic Chemistry Book

Practical Approaches to Biological Inorganic Chemistry


  • Author : Robert R. Crichton
  • Publisher : Elsevier
  • Release Date : 2019-09-10
  • Genre: Science
  • Pages : 504
  • ISBN 10 : 9780444642264

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Practical Approaches to Biological Inorganic Chemistry Excerpt :

Practical Approaches to Biological Inorganic Chemistry, Second Edition, reviews the use of spectroscopic and related analytical techniques to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique, including relevant theory, a clear explanation of what it is, how it works, and how the technique is actually used to evaluate biological structures. New chapters cover Raman Spectroscopy and Molecular Magnetochemistry, but all chapters have been updated to reflect the latest developments in discussed techniques. Practical examples, problems and many color figures are also included to illustrate key concepts. The book is designed for researchers and students who want to learn both the basics and more advanced aspects of key methods in biological inorganic chemistry. Presents new chapters on Raman Spectroscopy and Molecular Magnetochemistry, as well as updated figures and content throughout Includes color images throughout to enable easier visualization of molecular mechanisms and structures Provides worked examples and problems to help illustrate and test the reader’s understanding of each technique Written by leading experts who use and teach the most important techniques used today to analyze complex biological structures

Biological Inorganic Chemistry Book

Biological Inorganic Chemistry


  • Author : Robert R. Crichton
  • Publisher : Academic Press
  • Release Date : 2018-05-23
  • Genre: Science
  • Pages : 692
  • ISBN 10 : 9780128117422

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Biological Inorganic Chemistry Excerpt :

Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students. Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Auth

Biological Inorganic Chemistry Book

Biological Inorganic Chemistry


  • Author : Robert R. Crichton
  • Publisher : Elsevier
  • Release Date : 2007-12-11
  • Genre: Science
  • Pages : 381
  • ISBN 10 : 0080556221

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Biological Inorganic Chemistry Excerpt :

The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Biological Inorganic Chemistry Book

Biological Inorganic Chemistry


  • Author : Robert R. Crichton
  • Publisher : Elsevier
  • Release Date : 2012-02-02
  • Genre: Science
  • Pages : 474
  • ISBN 10 : 9780444537829

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Biological Inorganic Chemistry Excerpt :

The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. This revised and expanded text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten, chromium and selected non-metals. The final five chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Applications of Physical Methods to Inorganic and Bioinorganic Chemistry Book

Applications of Physical Methods to Inorganic and Bioinorganic Chemistry


  • Author : Robert A. Scott
  • Publisher : John Wiley & Sons
  • Release Date : 2013-02-19
  • Genre: Science
  • Pages : 592
  • ISBN 10 : 9781118625286

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Applications of Physical Methods to Inorganic and Bioinorganic Chemistry Excerpt :

Modern spectroscopic and instrumental techniques are essential tothe practice of inorganic and bioinorganic chemistry. This firstvolume in the new Wiley Encyclopedia of Inorganic ChemistryMethods and Applications Series provides a consistent andcomprehensive description of the practical applicability of a largenumber of techniques to modern problems in inorganic andbioinorganic chemistry. The outcome is a text that providesinvaluable guidance and advice for inorganic and bioinorganicchemists to select appropriate techniques, whilst acting as asource to the understanding of these methods. This volume is also available as part of Encyclopedia ofInorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007to 2010, representing areas of key developments in the field ofinorganic chemistry published in the Encyclopedia of InorganicChemistry. ahref="http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1119994284.html"Findout more/a.

Biological Inorganic Chemistry Book
Score: 4.5
From 4 Ratings

Biological Inorganic Chemistry


  • Author : Gray Bertini
  • Publisher : University Science Books
  • Release Date : 2007
  • Genre: Science
  • Pages : 794
  • ISBN 10 : 1891389432

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Biological Inorganic Chemistry Excerpt :

Part A.: Overviews of biological inorganic chemistry : 1. Bioinorganic chemistry and the biogeochemical cycles -- 2. Metal ions and proteins: binding, stability, and folding -- 3. Special cofactors and metal clusters -- 4. Transport and storage of metal ions in biology -- 5. Biominerals and biomineralization -- 6. Metals in medicine. -- Part B.: Metal ion containing biological systems : 1. Metal ion transport and storage -- 2. Hydrolytic chemistry -- 3. Electron transfer, respiration, and photosynthesis -- 4. Oxygen metabolism -- 5. Hydrogen, carbon, and sulfur metabolism -- 6. Metalloenzymes with radical intermediates -- 7. Metal ion receptors and signaling. -- Cell biology, biochemistry, and evolution: Tutorial I. -- Fundamentals of coordination chemistry: Tutorial II.

Iron Metabolism Book

Iron Metabolism


  • Author : Robert Crichton
  • Publisher : John Wiley & Sons
  • Release Date : 2016-05-31
  • Genre: Medical
  • Pages : 574
  • ISBN 10 : 9781118925614

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Iron Metabolism Excerpt :

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

Inorganic Chemical Biology Book

Inorganic Chemical Biology


  • Author : Gilles Gasser
  • Publisher : John Wiley & Sons
  • Release Date : 2014-04-14
  • Genre: Science
  • Pages : 432
  • ISBN 10 : 9781118684153

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Inorganic Chemical Biology Excerpt :

Understanding, identifying and influencing the biologicalsystems are the primary objectives of chemical biology. From this perspective, metal complexes havealways been of great assistance to chemical biologists, for example, in structural identificationand purification of essential biomolecules, for visualizing cellular organelles or to inhibitspecific enzymes. This inorganic side of chemical biology, which continues to receive considerableattention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques andApplications provides a comprehensive overview of the current and emerging role of metal complexes inchemical biology. Throughout all of the chapters there is a strong emphasis on fundamentaltheoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooksfor the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals inchemical biology • Cell and organism imaging and probing DNA using metal andmetal carbonyl complexes • Detection of metal ions, anions and small molecules usingmetal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts inliving cells Written by a team of international experts, Inorganic ChemicalBiology: Principles, Techniques and Applications is a must-have for bioinorganic,bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

Metal Ions in Biochemistry Book

Metal Ions in Biochemistry


  • Author : Pabitra Krishna Bhattacharya
  • Publisher : CRC Press
  • Release Date : 2020-12-13
  • Genre: Science
  • Pages : 428
  • ISBN 10 : 9781000292664

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Metal Ions in Biochemistry Excerpt :

The second edition of Metal Ions in Biochemistry deals with the multidisciplinary subject of bio-inorganic chemistry, encompassing the disciplines of inorganic chemistry, biochemistry and medicine. The book deals with the role of metal ions in biochemistry, emphasising that biochemistry is mainly the chemistry of metal-biochemical complexes. Hence, the book starts with the structures of biochemicals and the identification of their metal binding sites. Thermodynamic and kinetic properties of the complexes are explained from the point of view of the nature of metal-ligand bonds. Various catalytic and structural roles of metal ions in biochemicals are discussed in detail. Features The role of Na+ and K+ in brain chemistry. The role of zinc insulin in glucose metabolism and its enhancement by vanadium and chromium compounds. Discussion of the role of zinc signals, zinc fingers and cascade effect in biochemistry. Haemoglobin synthesis and the role of vitamin B12 in it. The role of lanthanides in biochemical systems. A detailed discussion of the role of non-metals in biochemistry, a topic missing in most of the books on bio-inorganic chemistry. The study of bio-inorganic chemistry makes biochemists rethink the mechanistic pathways of biochemical reactions mediated by metal ions. There is a realisation of the role of metal complexes and inorganic ions as therapeutics such as iron in leukaemia, thalassemia and sickle cell anaemia, iodine in hypothyroidism and zinc, vanadium and chromium in glucose metabolism. The most recent realisation is of the use of zinc in the prevention and treatment of COVID-19.

Chemistry at Extreme Conditions Book

Chemistry at Extreme Conditions


  • Author : M.R. Manaa
  • Publisher : Elsevier
  • Release Date : 2005-03-02
  • Genre: Science
  • Pages : 536
  • ISBN 10 : 9780080456997

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Chemistry at Extreme Conditions Excerpt :

Chemistry at Extreme Conditions covers those chemical processes that occur in the pressure regime of 0.5–200 GPa and temperature range of 500–5000 K and includes such varied phenomena as comet collisions, synthesis of super-hard materials, detonation and combustion of energetic materials, and organic conversions in the interior of planets. The book provides an insight into this active and exciting field of research. Written by top researchers in the field, the book covers state of the art experimental advances in high-pressure technology, from shock physics to laser-heating techniques to study the nature of the chemical bond in transient processes. The chapters have been conventionally organised into four broad themes of applications: biological and bioinorganic systems; Experimental works on the transformations in small molecular systems; Theoretical methods and computational modeling of shock-compressed materials; and experimental and computational approaches in energetic materials research. * Extremely practical book containing up-to-date research in high-pressure science * Includes chapters on recent advances in computer modelling * Review articles can be used as reference guide

Bioinorganic Chemistry Book

Bioinorganic Chemistry


  • Author : Dieter Rehder
  • Publisher : OUP Oxford
  • Release Date : 2014-03
  • Genre: Science
  • Pages : 256
  • ISBN 10 : 0199655197

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Bioinorganic Chemistry Excerpt :

Bioinorganic Chemistry provides a broad overview of this dynamic field, reviewing the key chemical elements that have important biological function, and exploring how the chemistry of these elements is central to the function of biological systems.

Medicinal and Biological Inorganic Chemistry Book

Medicinal and Biological Inorganic Chemistry


  • Author : Ajay Kumar Goswami
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release Date : 2022-01-19
  • Genre: Science
  • Pages : 148
  • ISBN 10 : 9781501516153

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Medicinal and Biological Inorganic Chemistry Excerpt :

The book provides a detailed state-of-the-art overview of inorganic chemistry applied to medicinal chemistry and biology. It covers the newly emerging field of metals in medicine and the future of medicinal inorganic chemistry. It is an essential reading for every researcher and student in medicinal and bioinorganic chemistry.

Principles of Bioinorganic Chemistry Book

Principles of Bioinorganic Chemistry


  • Author : Stephen J. Lippard
  • Publisher : University Science Books
  • Release Date : 1994
  • Genre: Science
  • Pages : 444
  • ISBN 10 : 0935702725

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Principles of Bioinorganic Chemistry Excerpt :

As one of the most dynamic fields in contemporary science, bioinorganic chemistry lies at a natural juncture between chemistry, biology, and medicine. This rapidly expanding field probes fascinating questions about the uses of metal ions in nature. Respiration, metabolism, photosynthesis, gene regulation, and nerve impulse transmission are a few of the many natural processes that require metal ions, and new systems are continually being discovered. The use of unnatural metals - which have been introduced into human biology as diagnostic probes and drugs - is another active area of tremendous medical significance. This introductory text, written by two pioneering researchers, is destined to become a landmark in the field of bioinorganic chemistry through its organized unification of key topics. Accessible to undergraduates, the book provides necessary background information on coordination chemistry, biochemistry, and physical methods before delving into topics that are central to the field: What metals are chosen and how are they taken up by cells? How are the concentrations of metals controlled and utilized in cells? How do metals bind to and fold biomolecules? What principles govern electron transfer and substrate binding and activation reactions? How do proteins fine-tune the properties of metals for specific functions? For each topic discussed, fundamentals are identified and then clarified through selected examples. An extraordinarily readable writing style combines with chapter-opening principles, study problems, and beautifully rendered two-color illustrations to make this book an ideal choice for instructors, students, and researchers in the chemical, biological, and medicalcommunities.

Medicinal Inorganic Chemistry Book

Medicinal Inorganic Chemistry


  • Author : Jonathan L. Sessler
  • Publisher : Amer Chemical Society
  • Release Date : 2005
  • Genre: Medical
  • Pages : 480
  • ISBN 10 : UOM:39015062459931

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Medicinal Inorganic Chemistry Excerpt :

This book, a compilation by experts in the field, is designed to provide an introduction to the area of medicinal inorganic chemistry and to summarize current, state-of-the-art developments in the field. Medicinal inorganic chemistry represents a key thrust area in medicine and biological inorganic chemistry. It is one of great current excitement and achievement. The field of metals in medicine represents an approximate $3 billion dollar a year industry, with successes in the area of Tc- and Gd-based imaging agents and Pt-based cancer therapeutics being major contributors to this bottom line. It has become increasingly apparent, however, that metal-based pharmaceuticals can play a prominent role in areas outside of imaging and oncology, including in those associated with the diagnosis and treatment of metabolism- and genetic disorders, cardiovascular disease, gene therapy, inflammation, reperfusion injury, stroke, diabetes, ALS, malaria, and neurological disease to name but a few. A objective of this book, therefore, is to highlight these opportunities for future advances and to foster further interactions between those working in the metal-based drug development, including imaging agents, and those engaged in the more classic pharmaceutical industries.