Precision Medicine in Pediatric Health Book

Precision Medicine in Pediatric Health


  • Author : Olaf Bodamer
  • Publisher : Academic Press
  • Release Date : 2020-03
  • Genre: Science
  • Pages : 456
  • ISBN 10 : 0128170166

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Precision Medicine in Pediatric Health Book Description :

Precision Medicine in Pediatric Health is an invaluable resource on state-of-the-art tools, technologies and social and ethical issues involved in fully realizing precision medicine in new pediatric research and healthcare. The book adopts a holistic approach that is grounded in key learning points and practical case studies of interest to interdisciplinary teams of researchers and clinicians working in pediatrics. Chapters provide a thorough introduction to basic principles of precision medicine, its growing role in research and clinical care, relevant technologies and digital health. From there, the book examines best practices and offers support for implementing precision medicine in research and clinical settings. Chapters are devoted to varying specialties, such as prenatal and fetal health, oncology, cardiology, neurology, rare diseases, developmental disorders, and precision therapeutics, including small molecule and gene and cell-based therapies. These sections are followed by a close look at ethical, legal and social implications of precision medicine in pediatrics, patient perspectives and next steps in research and clinical translation. Presents succinct commentary and key learning points that support the translation of precision and genomic medicine Highlights the practical use of precision medicine in the management of pediatric patients Provides a comprehensive volume that is written and edited by leading researchers, clinicians and scientists

Precision Medicine for Investigators  Practitioners and Providers Book

Precision Medicine for Investigators Practitioners and Providers


  • Author : Joel Faintuch
  • Publisher : Academic Press
  • Release Date : 2019-11-16
  • Genre: Science
  • Pages : 640
  • ISBN 10 : 9780128191798

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Precision Medicine for Investigators Practitioners and Providers Book Description :

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

Progress and Challenges in Precision Medicine Book

Progress and Challenges in Precision Medicine


  • Author : Mukesh Verma
  • Publisher : Academic Press
  • Release Date : 2016-12-22
  • Genre: Medical
  • Pages : 344
  • ISBN 10 : 9780128095027

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Progress and Challenges in Precision Medicine Book Description :

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Discovering Precision Health Book

Discovering Precision Health


  • Author : Lloyd Minor
  • Publisher : John Wiley & Sons
  • Release Date : 2020-01-23
  • Genre: Medical
  • Pages : 288
  • ISBN 10 : 9781119672685

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Discovering Precision Health Book Description :

Today we are on the brink of a much-needed transformative moment for health care. The U.S. health care system is designed to be reactive instead of preventive. The result is diagnoses that are too late and outcomes that are far worse than our level of spending should deliver. In recent years, U.S. life expectancy has been declining. Fundamental to realizing better health, and a more effective health care system, is advancing the disruptive thinking that has spawned innovation in Silicon Valley and throughout the world. That's exactly what Stanford Medicine has done by proposing a new vision for health and health care. In Discovering Precision Health, Lloyd Minor and Matthew Rees describe a holistic approach that will set health care on the right track: keep people healthy by preventing disease before it starts and personalize the treatment of individuals precisely, based on their specific profile. With descriptions of the pioneering work undertaken at Stanford Medicine, complemented by fascinating case studies of innovations from entities including the Chan Zuckerberg Biohub, GRAIL, and Impossible Foods, Minor and Rees present a dynamic vision for the future of individual health and health care. You'll see how tools from smartphone technology to genome sequencing to routine blood tests are helping avert illness and promote health. And you'll learn about the promising progress already underway in bringing greater precision to the process of predicting, preventing, and treating a range of conditions, including allergies, mental illness, preterm birth, cancer, stroke, and autism. The book highlights how biomedical advances are dramatically improving our ability to treat and cure complex diseases, while emphasizing the need to devote more attention to social, behavioral, and environmental factors that are often the primary determinants of health. The authors explore thought-provoking topics including: The unlikely role of Google Glass in treating autism How gene editing

Toward Precision Medicine Book

Toward Precision Medicine


  • Author : National Research Council
  • Publisher : National Academies Press
  • Release Date : 2012-01-16
  • Genre: Medical
  • Pages : 142
  • ISBN 10 : 9780309222228

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Toward Precision Medicine Book Description :

Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Precision Health and Medicine Book

Precision Health and Medicine


  • Author : Arash Shaban-Nejad
  • Publisher : Springer
  • Release Date : 2019-08-01
  • Genre: Technology & Engineering
  • Pages : 197
  • ISBN 10 : 9783030244095

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Precision Health and Medicine Book Description :

This book highlights the latest advances in the application of artificial intelligence to healthcare and medicine. It gathers selected papers presented at the 2019 Health Intelligence workshop, which was jointly held with the Association for the Advancement of Artificial Intelligence (AAAI) annual conference, and presents an overview of the central issues, challenges, and potential opportunities in the field, along with new research results. By addressing a wide range of practical applications, the book makes the emerging topics of digital health and precision medicine accessible to a broad readership. Further, it offers an essential source of information for scientists, researchers, students, industry professionals, national and international public health agencies, and NGOs interested in the theory and practice of digital and precision medicine and health, with an emphasis on risk factors in connection with disease prevention, diagnosis, and intervention.

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases Book

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases


  • Author : Ioana Agache
  • Publisher : Academic Press
  • Release Date : 2018-09-19
  • Genre: Medical
  • Pages : 228
  • ISBN 10 : 9780128134726

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Implementing Precision Medicine in Best Practices of Chronic Airway Diseases Book Description :

Implementing Precision Medicine in Best Practices of Chronic Airway Diseases provides a comprehensive overview of the application of precision medicine in airway diseases with a goal of promoting optimal control of disease, higher patient satisfaction and disease prevention. As medical research continues to fund this area, the book highlights the need for implementation of the principles of precision medicine into the bedside management of chronic airway diseases. It is clear that chronic airway diseases are heterogeneous and that a personalized approach is warranted whereby treatment is tailored to the level of the individual patient. Written for basic researchers, medical doctors and other healthcare practitioners this book provides guidance on the implementation of the principles of precision medicine into further research and daily clinical practice. Bridges the gap between precision medicine research and the implementation of the principles into daily clinical practice Includes contributions from key opinion leaders in the field of airway disease giving a worldwide perspective Discusses precision medicine in terms of personalized and stratified medicine, biomarkers, prediction of success, participation of the patient and prevention of disease

Precision Public Health Book

Precision Public Health


  • Author : Tarun Weeramanthri
  • Publisher : Frontiers Media SA
  • Release Date : 2018-06-25
  • Genre:
  • Pages :
  • ISBN 10 : 9782889455010

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Precision Public Health Book Description :

Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.

Apoptosis in Cancer Pathogenesis and Anti cancer Therapy Book

Apoptosis in Cancer Pathogenesis and Anti cancer Therapy


  • Author : Christopher D. Gregory
  • Publisher : Springer
  • Release Date : 2016-08-24
  • Genre: Medical
  • Pages : 247
  • ISBN 10 : 9783319394060

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Apoptosis in Cancer Pathogenesis and Anti cancer Therapy Book Description :

This book discusses properties of apoptosis and other cell death modalities in cancer pathogenesis and treatment. Its nine chapters discuss modulation of anti-tumor inflammatory and immune responses, effects on the tumor microenvironment, to strategies for improving pro-apoptotic therapies, mechanisms and implications for disease pathogenesis, axl and mer receptor tyrosine kinases, immunogenic apoptotic cell death and anti-cancer immunity and cancer cell death-inducing radiotherapy. This book places the onco-biology of apoptosis in clear and objective perspective through an expertly synthesized series of reviews. Apoptosis in Cancer Pathogenesis and Anti-cancer Therapy is a deft and thorough exploration of cutting-edge research in apoptosis and anti-cancer mechanisms from basic biology to oncology. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike.

Personalizing Precision Medicine Book

Personalizing Precision Medicine


  • Author : Kristin Ciriello Pothier
  • Publisher : John Wiley & Sons
  • Release Date : 2017-10-02
  • Genre: Medical
  • Pages : 272
  • ISBN 10 : 9781118792117

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Personalizing Precision Medicine Book Description :

The author uses decades of experience and interviews with experts in precision medicine to explain past, present, and future of precision medicine. She reviews the full continuum of personalizing precision medicine, including diagnostics, therapeutics, big data, supportive care, regulation, and reimbursement and innovation in precision medicine worldwide. • Combines a unique cross section of history, current technologies, and future directions for how precision medicine has and will affect people worldwide • Reviews precision medicine around the world, including the US, China, Japan, the Middle East, India, Europe, and Latin America • Discusses a number of diseases areas – cancer, cardiovascular, neurodegenerative, infectious disease, pain, immunology, rare diseases • Includes information and quotes from over 100 interviews with key industry experts in biotech, pharma, informatics, diagnostics, health providers, advocacy groups, and more. • Includes stories illustrating current issues and future promises in precision medicine for a human touch

Relevance of Health Literacy to Precision Medicine Book

Relevance of Health Literacy to Precision Medicine


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2016-12-04
  • Genre: Medical
  • Pages : 124
  • ISBN 10 : 9780309447324

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Relevance of Health Literacy to Precision Medicine Book Description :

On January 20, 2015, President Obama announced the Precision Medicine Initiative (PMI) in his State of the Union address. The PMI, by developing new approaches for detecting, measuring, and analyzing a wide range of biomedical information including molecular, genomic, cellular, clinical, behavioral, physiological, and environmental parameters, is intended to enable a new era of medicine in which researchers, providers, and patients work together to develop individualized care. Part of this effort included the creation of a national, large-scale research participant group, or cohort. The PMI Cohort Program is aimed at extending precision medicine to many diseases, including both rare and common diseases such as diabetes, heart disease, Alzheimer's disease, obesity, and mental illnesses such as depression, bipolar disorder, and schizophrenia, by building a national research cohort of 1 million or more U.S. participants. An important challenge to assembling the PMI Cohort will be to reach individuals who are socioeconomically disadvantaged. Individuals who are socioeconomically disadvantaged have lower health literacy; often belong to racial, ethnic, and minority communities; and are often less likely to participate in research studies and biorepositories. To explore possible strategies and messaging designs, the Roundtable on Health Literacy formed an ad hoc committee charged with planning and conducting a 1-day public workshop on the intersection of health literacy and precision medicine. The workshop participants discussed a variety of topics including an overview of precision medicine and its potential, the relevance of health literacy to the success of precision medicine efforts, and perspectives and understanding of different groups, such as health care providers, consumers, and insurers. This publication summarizes the presentations and discussions from the workshop.

Pediatric Oncology Nursing Book

Pediatric Oncology Nursing


  • Author : Pamela S. Hinds
  • Publisher : Springer Nature
  • Release Date : 2020-01-23
  • Genre: Medical
  • Pages : 348
  • ISBN 10 : 9783030258047

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Pediatric Oncology Nursing Book Description :

This book presents the current state of the nursing science in topics relevant to the care of pediatric oncology patients and their families across the treatment trajectory and is framed within a precision health framework. The spectrum of topics covered is wide, including, for example, symptom management, self-care management, exercise and physical activity, family-centered care, palliative care, the role of the nurse in treatment decision making, patient and nurse resiliency, survivorship, and genetic counseling. Throughout, there is a focus on the implications of research for nursing practice, highlighting which elements of the available evidence are ready for translation into practice and which are not. In addition, careful attention is paid to the role that nursing can play in further advancing science through clinical research. The authors are leading experts from across the globe. The book will be of special interest for pediatric oncology nurses, including direct care nurses, research nurses, and nursing leaders, and will also be a stimulating source for researchers and non-oncology nurses.

Precision Medicine  A Guide to Genomics in Clinical Practice Book

Precision Medicine A Guide to Genomics in Clinical Practice


  • Author : Jeanette J. McCarthy
  • Publisher : McGraw Hill Professional
  • Release Date : 2017-01-05
  • Genre: Medical
  • Pages : 304
  • ISBN 10 : 9781259644146

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Precision Medicine A Guide to Genomics in Clinical Practice Book Description :

Incorporate genomics into every applicable area of your clinical practice with this complete how-to guide Precision Medicine: A Guide to Genomics in Clinical Practice is a comprehensive, yet succinct overview of the practice of genomic medicine. It is written for general healthcare practitioners, specialists, and trainees with the goal of providing detailed guidance on how to incorporate genomic medicine into daily practice. Features that make this book valuable to every practice: •Intentionally avoids excessive technical content and consistently emphasizes real-life patient care and decision support •Follows the course of a human life, beginning before conception through pregnancy, childhood, and adulthood, discussing the current and future applications of genomics and precision medicine at each stage •Organization allows healthcare providers to quickly and easily find the information relevant to their practice. •The authors highlight common pitfalls – technical and ethical – that might complicate the delivery of quality genomic healthcare •Enhanced by eleven valuable appendices that cover important topics ranging from the basics of genetics to ethical issues to regulation and reimbursement If you are searching for a clinically relevant, non-technical resource that will teach you how genomic medicine can and should be practiced in your specific field of interest, Precision Medicine: A Guide to Genomics in Clinical Practicebelongs on your desk.

Precision Medicine  A Multidisciplinary Approach Book

Precision Medicine A Multidisciplinary Approach


  • Author : Joel J. Heidelbaugh
  • Publisher : Elsevier
  • Release Date : 2020-05-31
  • Genre: Medical
  • Pages : 240
  • ISBN 10 : 0323789471

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Precision Medicine A Multidisciplinary Approach Book Description :

Welcome to the Clinics Collections! We have taken a multidisciplinary approach and selected the most recent and vital articles throughout all of our Clinics series and combined them into a single source on Precision Medicine. Articles are featured from multiple Clinics to highlight the range of specialties covering this major medical issue. Such information is essential to successful interdisciplinary teamwork and patient care. The articles within, written from different medical perspectives, will give deeper insight into how each specialty cares for its patients. The challenge in Precision Medicine involves specialized treatment planning with the ultimate goal of successful patient outcomes. The articles selected provide a unique entry into sharing best concepts for the entire medical team to learn and implement. Areas of focus include breast cancer, lung cancer, melanoma, arthritis, sleep medicine, and pediatric oncology. Each article begins with keywords and key points for immediate access to the most critical information. Articles are presented in an easy-to-digest and concisely worded format.

The Essential Guide to N of 1 Trials in Health Book

The Essential Guide to N of 1 Trials in Health


  • Author : Jane Nikles
  • Publisher : Springer
  • Release Date : 2015-10-05
  • Genre: Medical
  • Pages : 245
  • ISBN 10 : 9789401772006

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The Essential Guide to N of 1 Trials in Health Book Description :

N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world’s leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.

Clinical Precision Medicine Book

Clinical Precision Medicine


  • Author : Judy S. Crabtree
  • Publisher : Academic Press
  • Release Date : 2019-11-15
  • Genre: Medical
  • Pages : 112
  • ISBN 10 : 9780128204023

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Clinical Precision Medicine Book Description :

Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics Features chapter contributions from leaders in the field Consolidates fundamental concepts and current practices of precision medicine in one convenient resource

Biomarker Tests for Molecularly Targeted Therapies Book

Biomarker Tests for Molecularly Targeted Therapies


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2016-07-30
  • Genre: Medical
  • Pages : 292
  • ISBN 10 : 9780309381345

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Biomarker Tests for Molecularly Targeted Therapies Book Description :

Every patient is unique, and the evolving field of precision medicine aims to ensure the delivery of the right treatment to the right patient at the right time. In an era of rapid advances in biomedicine and enhanced understanding of the genetic basis of disease, health care providers increasingly have access to advanced technologies that may identify molecular variations specific to an individual patient, which subsequently can be targeted for treatment. Known as biomarker tests for molecularly targeted therapies, these complex tests have the potential to enable the selection of the most beneficial treatment (and also to identify treatments that may be harmful or ineffective) for the molecular underpinnings of an individual patient's disease. Such tests are key to unlocking the promise of precision medicine. Biomarker tests for molecularly targeted therapies represent a crucial area of focus for developing methods that could later be applicable to other areas of precision medicine. The appropriate regulatory oversight of these tests is required to ensure that they are accurate, reliable, properly validated, and appropriately implemented in clinical practice. Moreover, common evidentiary standards for assessing the beneficial impact of biomarker-guided therapy selection on patient outcomes, as well as the effective collection and sharing of information related to those outcomes, are urgently needed to better inform clinical decision making. Biomarker Tests of Molecularly Targeted Therapies examines opportunities for and challenges to the use of biomarker tests to select optimal therapy and offers recommendations to accelerate progress in this field. This report explores regulatory issues, reimbursement issues, and clinical practice issues related to the clinical development and use of biomarker tests for targeting therapies to patients. Properly validated, appropriately implemented biomarker tests hold the potential to enhance patient care and improve outcomes, and

Gender in Psycho Oncology Book

Gender in Psycho Oncology


  • Author : PhD Youngmee Kim
  • Publisher : Oxford University Press
  • Release Date : 2018-03-30
  • Genre: Medical
  • Pages : 224
  • ISBN 10 : 9780190462260

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Gender in Psycho Oncology Book Description :

As cancer treatment has evolved toward precision medicine, psychosocial research and practices for cancer patients and their family members have also raised awareness of the need for a personalized, patient-focused, family-oriented approach in the Psycho-Oncology field. Gender in Psycho-Oncology is the first book of its kind to provide comprehensive views on the role of gender in the adjustment of the individual and the patient-caregiver pair when dealing with cancer. The text explores the significant role of gender in diverse pairings of genders between the patient and the caregiver. It also highlights the importance of age, generation, and socio-cultural characteristics; the illness trajectory and lifespan trajectory of the individual and the patient-caregiver pair; and an ongoing sociocultural movement that is changing social role expectations based on gender. Offering both fundamental and practical information, Gender in Psycho-Oncology is an ideal book for healthcare practitioners from a spectrum of disciplines in the Psycho-Oncology field.

Keep It Up Book

Keep It Up


  • Author : Florence Comite
  • Publisher : Rodale
  • Release Date : 2013-10-08
  • Genre: Health & Fitness
  • Pages : 336
  • ISBN 10 : 9781609611019

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Keep It Up Book Description :

Do You Have Low T? As a man ages, a slow decline takes root that, day to day, is imperceptible. Sometime around age 30, levels of the male hormone testosterone begin to drop each year. One morning he looks in the mirror and sees someone who he doesn't recognize. He's tired-looking, lacks motivation, his belly is sagging over his belt, his mind is foggy, and maybe his sex drive has evaporated. What happened? Oh, you're just getting older, people tell him—even his doctor! Endocrinologist Florence Comite, MD, doesn't believe we should accept aging as is. In fact, she has helped many men to turn around their health for the better. She believes any man can restore his body, mind, and energy; prevent disease; and feel strong, confident, and in control once again. How? By using her Precision Medicine analysis, a highly personalized plan of action designed to combat the decline triggered by the age-related fall in testosterone. This book will show you how to quantify your own health and then make lifestyle changes that will reduce your belly fat and risk of diabetes, revitalize your sex drive and strengthen your erections, and give you more muscle and greater mental agility. Because testosterone affects all of the above aspects of a man's vitality, Dr. Comite shows readers how the cutting-edge science of hormone optimization for men with low testosterone is an effective way to prevent the disorders of aging.

Pediatric Informatics Book

Pediatric Informatics


  • Author : Christoph Lehmann
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-07-16
  • Genre: Medical
  • Pages : 484
  • ISBN 10 : 9780387764467

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Pediatric Informatics Book Description :

Now is a critical time in pediatric informatics. As information technologies—electronic health records (EHRs), personal health records (PHRs), computerized physician order entry (CPOE)—and standards (HL7) are developed to improve the quality of health care, it is imperative for policy makers and pediatricians to be aware of their impact on pediatric care and child health. Informed child advocates must be at the planning table as national and regional health information networks are developed to insure the unique health care needs of children are being met. Pediatric Informatics: Computer Applications in Child Health is a current digest of the important trends in pediatric informatics, written by leading experts in the field. This book explores how the management of biomedical data, information, and knowledge can optimize and advance child health. The contributors investigate the specific importance of pediatric informatics is derived from the biological, psychological, social and cultural needs that the distinguish children from other populations. These distinctions create complexities in the management of pediatric data and information that make children a vulnerable population and require the development of a new body of knowledge in pediatric informatics.