Progress and Challenges in Precision Medicine Book

Progress and Challenges in Precision Medicine


  • Author : Mukesh Verma
  • Publisher : Academic Press
  • Release Date : 2016-12-22
  • Genre: Medical
  • Pages : 344
  • ISBN 10 : 9780128095027

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Progress and Challenges in Precision Medicine Excerpt :

Progress and Challenges in Precision Medicine presents an insightful overview to the myriad factors of personalized and precision medicine. The availability of the human genome, large amounts of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the age of personalized and precision medicine. Bringing together a global range of experts on precision medicine, this book collects previously scattered information into one concise volume which covers the most important developments so far in precision medicine and also suggests the most likely avenues for future development. The book includes clinical information, informatics, public policy implications, and information on case studies. It is a useful reference and background work for students, researchers, and clinicians working in the biomedical and medical fields, as well as policymakers in the health sciences. Provides an overview of the growing field of precision medicine Contains chapters from geographically diverse experts in their field Explores important aspects of precision medicine, including applications, ethics, and development

Precision Medicine Book

Precision Medicine


  • Author : Hans-Peter Deigner
  • Publisher : Academic Press
  • Release Date : 2018-02-15
  • Genre: Medical
  • Pages : 374
  • ISBN 10 : 9780128054338

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Precision Medicine Excerpt :

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation Encompasses easy access to relevant approaches, interactions and original literature

Precision Cancer Medicine Book

Precision Cancer Medicine


  • Author : Sameek Roychowdhury
  • Publisher : Springer Nature
  • Release Date : 2020-01-02
  • Genre: Medical
  • Pages : 196
  • ISBN 10 : 9783030236373

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Precision Cancer Medicine Excerpt :

Genomic sequencing technologies have augmented the classification of cancer beyond tissue of origin and towards a molecular taxonomy of cancer. This has created opportunities to guide treatment decisions for individual patients with cancer based on their cancer’s unique molecular characteristics, also known as precision cancer medicine. The purpose of this text will be to describe the contribution and need for multiple disciplines working together to deliver precision cancer medicine. This entails a multi-disciplinary approach across fields including molecular pathology, computational biology, clinical oncology, cancer biology, drug development, genetics, immunology, and bioethics. Thus, we have outlined a current text on each of these fields as they work together to overcome various challenges and create opportunities to deliver precision cancer medicine. As trainees and junior faculty enter their respective fields, this text will provide a framework for understanding the role and responsibility for each specialist to contribute to this team science approach.

Precision Public Health Book

Precision Public Health


  • Author : Tarun Weeramanthri
  • Publisher : Frontiers Media SA
  • Release Date : 2018-06-25
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 9782889455010

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Precision Public Health Excerpt :

Precision Public Health is a new and rapidly evolving field, that examines the application of new technologies to public health policy and practice. It draws on a broad range of disciplines including genomics, spatial data, data linkage, epidemiology, health informatics, big data, predictive analytics and communications. The hope is that these new technologies will strengthen preventive health, improve access to health care, and reach disadvantaged populations in all areas of the world. But what are the downsides and what are the risks, and how can we ensure the benefits flow to those population groups most in need, rather than simply to those individuals who can afford to pay? This is the first collection of theoretical frameworks, analyses of empirical data, and case studies to be assembled on this topic, published to stimulate debate and promote collaborative work.

Me Medicine vs  We Medicine Book

Me Medicine vs We Medicine


  • Author : Donna Dickenson
  • Publisher : Columbia University Press
  • Release Date : 2013-05-28
  • Genre: Medical
  • Pages : 296
  • ISBN 10 : 9780231159746

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Me Medicine vs We Medicine Excerpt :

Technologies such as direct-to-consumer genetic testing, pharmacogenetically developed therapies in cancer care, private umbilical cord blood banking, and neurocognitive enhancement claim to cater to an individual's specific biological character, and, in some cases, these technologies have shown powerful potential. Yet in others they have produced negligible or even negative results. Donna Dickenson examines the economic and political factors fueling the Me Medicine phenomenon and explores how, over time, this paradigm shift in how we approach our health might damage our individual and collective well-being. Drawing on the latest findings from leading scientists, social scientists, and political analysts, she critically examines four possible hypotheses driving the Me Medicine moment: a growing sense of threat; a wave of patient narcissism; corporate interests driving new niche markets; and the dominance of personal choice as a cultural value. She concludes with insights from political theory that emphasize a conception of the commons and the steps we can take to restore its value to modern biotechnology.

A Theranostic and Precision Medicine Approach for Female Specific Cancers Book

A Theranostic and Precision Medicine Approach for Female Specific Cancers


  • Author : Rama Rao Malla
  • Publisher : Academic Press
  • Release Date : 2020-11-06
  • Genre: Science
  • Pages : 318
  • ISBN 10 : 9780128226926

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A Theranostic and Precision Medicine Approach for Female Specific Cancers Excerpt :

A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of biomedical field who need to understand the most recent and promising approaches to manage FSCs. Explores new diagnostic biomarkers surrounding the early detection and prognosis of FSCs Examines new genetic and molecularly targeted approaches for the treatment of these aggressive diseases Discusses new theranostic approaches that combine diagnosis and treatment through the use of nanotechnology in FSCs Addresses how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care

Precision Medicine and Artificial Intelligence Book

Precision Medicine and Artificial Intelligence


  • Author : Michael Mahler
  • Publisher : Elsevier
  • Release Date : 2021-04-15
  • Genre: Science
  • Pages : 300
  • ISBN 10 : 9780128202395

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Precision Medicine and Artificial Intelligence Excerpt :

Precision Medicine and Artificial Intelligence: The Perfect Fit for Autoimmunity covers background on AI, its link to PM, and examples of AI in healthcare, especially autoimmunity. The book highlights future perspectives and potential directions as artificial intelligence (AI) has gained significant attention in the past decade. Autoimmune diseases are complex and heterogeneous conditions, but exciting new developments and implementation tactics surrounding automated systems has enabled the generation of large amounts of data, making autoimmunity an ideal target for AI in the field of Precision Medicine (PM). More and more diagnostic products utilize AI, which is also starting to be supported by regulatory agencies such as the Food and Drug Administration (FDA). Knowledge generation by leveraging large data sets including demographic, environmental, clinical and biomarker data has the potential to not only impact the diagnosis of patients, but also disease prediction, prognosis and treatment options. Allows the readers to get a good overview of the field of Precision Medicine for autoimmune diseases and Artificial Intelligence Provides background, milestone and examples of precision medicine for autoimmune disease and artificial intelligence Proves the paradigm shift towards precision medicine driven by value-based systems Discusses future applications of precision medicine research using artificial intelligence

Toward Precision Medicine Book

Toward Precision Medicine


  • Author : National Research Council
  • Publisher : National Academies Press
  • Release Date : 2012-01-16
  • Genre: Medical
  • Pages : 142
  • ISBN 10 : 9780309222228

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Toward Precision Medicine Excerpt :

Motivated by the explosion of molecular data on humans-particularly data associated with individual patients-and the sense that there are large, as-yet-untapped opportunities to use this data to improve health outcomes, Toward Precision Medicine explores the feasibility and need for "a new taxonomy of human disease based on molecular biology" and develops a potential framework for creating one. The book says that a new data network that integrates emerging research on the molecular makeup of diseases with clinical data on individual patients could drive the development of a more accurate classification of diseases and ultimately enhance diagnosis and treatment. The "new taxonomy" that emerges would define diseases by their underlying molecular causes and other factors in addition to their traditional physical signs and symptoms. The book adds that the new data network could also improve biomedical research by enabling scientists to access patients' information during treatment while still protecting their rights. This would allow the marriage of molecular research and clinical data at the point of care, as opposed to research information continuing to reside primarily in academia. Toward Precision Medicine notes that moving toward individualized medicine requires that researchers and health care providers have access to very large sets of health- and disease-related data linked to individual patients. These data are also critical for developing the information commons, the knowledge network of disease, and ultimately the new taxonomy.

Omics for Personalized Medicine Book

Omics for Personalized Medicine


  • Author : Debmalya Barh
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-10-14
  • Genre: Medical
  • Pages : 832
  • ISBN 10 : 9788132211846

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Omics for Personalized Medicine Excerpt :

“Omics for Personalized Medicine” will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.

Biomarkers  Diagnostics and Precision Medicine in the Drug Industry Book

Biomarkers Diagnostics and Precision Medicine in the Drug Industry


  • Author : Abdel Halim
  • Publisher : Academic Press
  • Release Date : 2019-06-08
  • Genre: Medical
  • Pages : 294
  • ISBN 10 : 9780128161227

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Biomarkers Diagnostics and Precision Medicine in the Drug Industry Excerpt :

The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline, as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerate the time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. This book aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies, which includes standard-of-care approved assays as well as for-investigational-use and for-research-use-only assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. This book serves as a reference to drug developers, IVD providers, clinical labs, healthcare givers, academicians, and researchers for best practices to help increase the probability of success in drug development and improve patient management. Provides the unique insight of an expert with extensive experience in diagnostics and clinical laboratory on one side and drug discovery and development on the other side Addresses the challenges of drug development and precision medicine and suggests how to eliminate or mitigate these challenges through better utilization of biomarkers and diagnostics in drug development and patient management Features case studies and real-life examples from different classes of biomarkers on different platforms for different therapeutic areas and includes more than 200 illustrations

P5 eHealth  An Agenda for the Health Technologies of the Future Book

P5 eHealth An Agenda for the Health Technologies of the Future


  • Author : Gabriella Pravettoni
  • Publisher : Springer Nature
  • Release Date : 2019-11-29
  • Genre: Medical
  • Pages : 189
  • ISBN 10 : 9783030279943

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P5 eHealth An Agenda for the Health Technologies of the Future Excerpt :

This open access volume focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design. It provides practical guidelines and evidence based examples on how to design, implement, use and elevate new technologies for healthcare to support the management of incurable, chronic conditions. The volume further discusses the criticalities of eHealth, why it is difficult to employ eHealth from an organizational point of view or why patients do not always accept the technology, and how eHealth interventions can be improved in the future. By dealing with the state-of-the-art in eHealth technologies, this volume is of great interest to researchers in the field of physical and mental healthcare, psychologists, stakeholders and policymakers as well as technology developers working in the healthcare sector.

Genomic and Precision Medicine Book

Genomic and Precision Medicine


  • Author : Geoffrey S. Ginsburg
  • Publisher : Academic Press
  • Release Date : 2022-04-09
  • Genre: Science
  • Pages : 378
  • ISBN 10 : 9780128006535

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Genomic and Precision Medicine Excerpt :

Genomic and Precision Medicine: Oncology, Third Edition focuses on the applications of genome discovery as research points to personalized cancer therapies. Each chapter is organized to cover the application of genomics and personalized medicine tools and technologies to a) Risk Assessment and Susceptibility, b) Diagnosis and Prognosis, c) Pharmacogenomics and Precision Therapeutics, and d) Emerging and Future Opportunities in the field. Provides a comprehensive volume written and edited by oncology genomic specialists for oncology health providers Includes succinct commentary and key learning points that will assist providers with their local needs for implementation of genomic and personalized medicine into practice Presents an up-to-date overview on major opportunities for genomic and personalized medicine in practice Covers case studies that highlight the practical use of genomics in the management of patients

Annual Update in Intensive Care and Emergency Medicine 2018 Book

Annual Update in Intensive Care and Emergency Medicine 2018


  • Author : Jean-Louis Vincent
  • Publisher : Springer
  • Release Date : 2018-03-28
  • Genre: Medical
  • Pages : 709
  • ISBN 10 : 9783319736709

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Annual Update in Intensive Care and Emergency Medicine 2018 Excerpt :

The Annual Update compiles reviews of the most recent developments in experimental and clinical intensive care and emergency medicine research and practice in one comprehensive reference book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.