Protein Trafficking in Neurons Book
Score: 3
From 1 Ratings

Protein Trafficking in Neurons

  • Author : Andrew J. Bean
  • Publisher : Elsevier
  • Release Date : 2006-10-27
  • Genre: Science
  • Pages : 464
  • ISBN 10 : 0080465897

Protein Trafficking in Neurons Book Description :

The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and endocytosis, transport of receptors, trafficking of ion channels and transporters, comparison of trafficking mechanisms in neuronal vs. non-neuronal cell types, and the relationship between trafficking and neuronal diseases such as Alzheimer's, Huntington's and Prion Diseases. Provides a comprehensive examination of membrane/protein movement in neuronal function Sections on synapse development, synaptic transmission, and the role of trafficking in neurological disease Includes a focus on Molecular Mechanisms Illustrated with color summary pictures The only book examining protein trafficking and its functional implications, written by leaders in the field

The Neuronal Cytoskeleton  Motor Proteins  and Organelle Trafficking in the Axon Book

The Neuronal Cytoskeleton Motor Proteins and Organelle Trafficking in the Axon

  • Author :
  • Publisher : Academic Press
  • Release Date : 2016-01-12
  • Genre: Science
  • Pages : 534
  • ISBN 10 : 9780128033548

The Neuronal Cytoskeleton Motor Proteins and Organelle Trafficking in the Axon Book Description :

The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport. Covers an increasingly appreciated field in cell biology Includes both established and new technologies Contributed by experts in the field

Trafficking Inside Cells Book

Trafficking Inside Cells

  • Author : Nava Segev
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-05-30
  • Genre: Science
  • Pages : 445
  • ISBN 10 : 9780387938776

Trafficking Inside Cells Book Description :

This book covers the past, present and future of the intra-cellular trafficking field, which has made a quantum leap in the last few decades. It details how the field has developed and evolved as well as examines future directions.

Rab GTPases and Membrane Trafficking Book

Rab GTPases and Membrane Trafficking

  • Author : Laurence Porter
  • Publisher : Bentham Science Publishers
  • Release Date : 2012-05-21
  • Genre: Science
  • Pages : 180
  • ISBN 10 : 9781608053650

Rab GTPases and Membrane Trafficking Book Description :

"Ypt/Rab GTPases form the largest branch of the Ras-related small GTPase superfamily and regulate intracellular membrane trafficking in all eukaryotes. Since their discovery over two decades ago, a wealth of information has accumulated about the roles that"

Amyotrophic Lateral Sclerosis Book

Amyotrophic Lateral Sclerosis

  • Author : Muralidhar L. Hegde
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-08-26
  • Genre: Medical
  • Pages : 160
  • ISBN 10 : 9781838805807

Amyotrophic Lateral Sclerosis Book Description :

A flurry of recent research on the role of the RNA/DNA-binding proteins TDP-43 and FUS as well as a dozen other factors (e.g., C9ORF72 and profilin) has led to a new paradigm in our understanding of the pathobiology of the motor neuron disease, Amyotrophic Lateral Sclerosis (ALS). How these factors trigger neuromuscular dysfunction is critical for developing more effective ALS therapeutics. The ‘gain-of-toxicity’ or ‘loss-of-function’ of these etiological factors is a key question. Recent studies on the imbalance in genome damage versus repair have opened avenues for potential DNA repair-based therapeutics. This book highlights emerging science in the area of ALS and discusses key approaches and mechanisms essential for developing a cure for ALS.

Molecular Biology of the Neuron Book

Molecular Biology of the Neuron

  • Author : Brian Morris
  • Publisher : Oxford University Press
  • Release Date : 2004-04-08
  • Genre: Medical
  • Pages : 480
  • ISBN 10 : 0198509987

Molecular Biology of the Neuron Book Description :

This book is a valuable compendium of up-to-date reviews of neuronal molecular biology by leading researchers in the field. It covers all aspects of neuron structure and function, with the emphasis on genetic and molecular analysis.

Prions Book


  • Author : Ivo Nikolaev Sirakov
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-01-30
  • Genre: Medical
  • Pages : 82
  • ISBN 10 : 9781789850178

Prions Book Description :

The cellular prion protein (PrPC) is expressed as a cell surface protein mainly in the central and peripheral nervous system. The discovery that prions are infectious agents changed the concept of protein synthesis in modern biology and built a bridge between the genesis of infectious and genetic diseases. This book discusses the normal function of the PrPC and its modulatory role in synaptic mechanisms. It describes the pathophysiological processes that accompany TSE - neurotoxicity, loss of anti-inflammatory protective function, neuronal death including prion-induced autophagy and apoptosis, and accumulation of PrPSc in the cytoplasm of neurons. Another aspect outlined here is that some prion diseases show strain variations that determine their development, demonstrating their key role in the development and progression of TSE.

Molecular Biology of the Cell Book
Score: 4
From 2 Ratings

Molecular Biology of the Cell

  • Author : Bruce Alberts
  • Publisher :
  • Release Date : 2004
  • Genre:
  • Pages :
  • ISBN 10 : 0815332181

Molecular Biology of the Cell Book Description :

Presenilins and Alzheimer   s Disease Book

Presenilins and Alzheimer s Disease

  • Author : Steven G. Younkin
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Medical
  • Pages : 100
  • ISBN 10 : 9783642721038

Presenilins and Alzheimer s Disease Book Description :

The role of the familial Alzheimer's Disease genes called "presenilins" in causing neuronal cell death and Alzheimer-related pathology.

Neuronal Chloride Transporters in Health and Disease Book

Neuronal Chloride Transporters in Health and Disease

  • Author : Xin Tang
  • Publisher : Academic Press
  • Release Date : 2020-06
  • Genre: Medical
  • Pages : 650
  • ISBN 10 : 0128153180

Neuronal Chloride Transporters in Health and Disease Book Description :

Neuronal Chloride Transporters in Health and Disease introduces core concepts and recent advances surrounding the physiology and pathophysiology of neuronal chloride transporters, with particular focus on the KCC and NKCC families of proteins. Chloride transporter biology is reviewed, including its role in setting the transmembrane chloride gradient and in chloride transport-independent functions, such as regulating excitatory neurotransmission. Chapters also address post-translational modifications and the trafficking of chloride transporters, protein interaction partners, and the genetic and environmental factors that regulate expression in neurons. This new volume will provide readers with an up-to-date summary on recent advances in neuronal chloride transporter research, with a particular emphasis on key and emerging topics in the field.

Mobility and Proximity in Biological Membranes Book

Mobility and Proximity in Biological Membranes

  • Author : Sandor Damjanovich
  • Publisher : CRC Press
  • Release Date : 1994-03-03
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 0849349311

Mobility and Proximity in Biological Membranes Book Description :

Cell surface membranes have long been characterized as two-dimensional fluids whose mobile components are randomized by diffusion in the plane of the membrane bilayer. Recent research has indicated that cell surface membranes are highly organized and ordered and that important functional units of membranes appear as arrays of interacting molecules rather than as single, freely diffusing molecules. Mobility and Proximity in Biological Membranes provides an overview of the results obtained from biophysical methods for probing the organization of cell surface membranes. These results are presented in the context of detailed treatments of the theory and the technical demands of each of the methods. The book describes a versatile and easily applied mode for investigating molecular proximities in plasma membranes in a flow cytometer. Its analysis of lipid fluidity and viscosity of membranes and the rotational mobility of proteins offers intimate insight into the physical chemistry of biological membranes. The electrophysiology of lymphocytes is presented with focus on its importance in different diseases. New techniques are described, and new data, new possibilities, and future trends are presented by world experts. This book's chapters can serve both as guides to the existing literature and as starting points for new experiments and approaches associated with problems in membrane function.

GABA And Glutamate Book

GABA And Glutamate

  • Author : Janko Samardzic
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-03-21
  • Genre: Medical
  • Pages : 138
  • ISBN 10 : 9789535138211

GABA And Glutamate Book Description :

This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.

Encyclopedia of Molecular Pharmacology Book

Encyclopedia of Molecular Pharmacology

  • Author : Stefan Offermanns
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-08-14
  • Genre: Medical
  • Pages : 1505
  • ISBN 10 : 9783540389163

Encyclopedia of Molecular Pharmacology Book Description :

An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.

Principles of Neurobiology Book

Principles of Neurobiology

  • Author : Liqun Luo
  • Publisher : Garland Science
  • Release Date : 2020-09-05
  • Genre: Science
  • Pages : 734
  • ISBN 10 : 9781000096804

Principles of Neurobiology Book Description :

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience with an emphasis on how we know what we know. The text is organized around a series of key experiments to illustrate how scientific progress is made and helps upper-level undergraduate and graduate students discover the relevant primary literature. Written by a single author in a clear and consistent writing style, each topic builds in complexity from electrophysiology to molecular genetics to systems level in a highly integrative approach. Students can fully engage with the content via thematically linked chapters and will be able to read the book in its entirety in a semester-long course. Principles of Neurobiology is accompanied by a rich package of online student and instructor resources including animations, figures in PowerPoint, and a Question Bank for adopting instructors.