Purification and Characterization of Secondary Metabolites Book

Purification and Characterization of Secondary Metabolites


  • Author : Thomas E. Crowley
  • Publisher : Academic Press
  • Release Date : 2019-08-10
  • Genre: Medical
  • Pages : 214
  • ISBN 10 : 9780128139431

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Purification and Characterization of Secondary Metabolites Excerpt :

Purification and Characterization of Secondary Metabolites: A Laboratory Manual for Analytical and Structural Biochemistry provides students with working knowledge of the fundamental and advanced techniques of experimental biochemistry. Sections provide an overview of the microbiological and biochemical methods typically used for the purification of metabolites and discuss the biological significance of secondary metabolites secreted by three diverse species of bacteria. Additionally, this lab manual covers the theory and practice of the most commonly-used techniques of analytical biochemistry, UV-vis and IR spectrophotometry, high-performance liquid chromatography, mass spectrometry, X-ray crystallography and nuclear magnetic resonance, and how to evaluate and effectively use scientific data. Instructors will find this book useful because of the modular nature of the lab exercises included. Written in a logical, easy-to-understand manner, this book is an indispensable resource for both students and instructors. Offers project lab formats for students that closely simulate original research projects Provides instructional guidance for students to design their own experiments Presents advanced analytical techniques Includes access to a website with additional resources for instructors

Plant Secondary Metabolites Book

Plant Secondary Metabolites


  • Author : Anita S. Patil
  • Publisher : Studera Press
  • Release Date : 2020-02-20
  • Genre: Science
  • Pages : 296
  • ISBN 10 : 9789385883194

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Plant Secondary Metabolites Excerpt :

India is known for its Ayurvedic system of medicine significantly based on therapeutic plants. Medicinal plants are used since time immemorial due to its safety, efficacy, cultural acceptability and lesser side effects as compared to synthetic drugs. In this present book, a scientific approach has been extensively applied for isolation, purification and screening of biological potential based on bioassay-guided fractionation methods. More specifically, the traditional values of therapeutic plants are correlated with scientific approach for the validation of “drug- like properties”. This book is quite helpful for finding the hidden values of therapeutic approach of ethno-medicinal plants. This book is inclusively a soul combination of pharmacognosy, biotechnology, bioinformatics and nanotechnology which are the most thrusting subjects of today’s world. This book is a must-read for science students, research scholars and scientific community who are interested in plant science.

Plant Secondary Metabolism Engineering Book

Plant Secondary Metabolism Engineering


  • Author : Arthur Germano Fett-Neto
  • Publisher : Unknown
  • Release Date : 2022
  • Genre: Biochemical engineering
  • Pages : 262
  • ISBN 10 : 1071621858

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Plant Secondary Metabolism Engineering Excerpt :

This second edition provides detailed practical information on important methods employed in the engineering of plant secondary metabolism pathways. New and updated chapters guide readers through extraction, quantification, purification, localization, characterization, data mining and processing, biosynthesis modulation, and pathway engineering of representative classes of plant specialized metabolites. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, list of necessary materials and reagents, tips on troubleshooting and known pitfalls, and step-by-step descriptions of readily reproducible protocols. Authoritative and cutting-edge, Plant Secondary Metabolism Engineering: Methods and Protocols, Second Edition aims to be a useful practical guide to help researchers working in this exciting field.

Secondary Metabolite Biosynthesis and Metabolism Book

Secondary Metabolite Biosynthesis and Metabolism


  • Author : Richard J. Petroski
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 383
  • ISBN 10 : 9781461530121

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Secondary Metabolite Biosynthesis and Metabolism Excerpt :

This book was developed from the proceedings of the American Chemical Society, Division of Agricultural & Food Chemistry, subdivision of Natural Products Symposium "Biosynthesis and Metabolism of Secondary Natural Products" held in Atlanta, Georgia, April 1991. The objective of the conference was to bring together people from apparently diverse fields, ranging from biotechnology, metabolism, mechanistic organic chemistry, enzymology, fermentation, and biosynthesis, but who share a common interest in either the biosynthesis or the metabolism of natural products. It is our intention to help bridge the gap between the fields of mechanistic bio-organic chemistry and biotechnology. Our thanks go to Dr. Henry Yokoyama, co-organizer of the symposium, the authors who so kindly contributed chapters, the conference participants, and to those who assisted in the peer review process. We also thank the financial supporters of the symposium: ACS/AGFD, NIH General Medical Sciences, and the agricultural, pharmaceutical, biotechnology, and chromatography companies. A full list of the supporting corporations and institutions is given on the following page. Pharma-Tech and P.C., Inc. are manufacturers of instrumentation for high-speed countercurrent chromatography. We thank the Agricultural Research Service and the U. S. Department of Agriculture for granting me permission to co-organize the conference and for us to complete the book. Richard J. Petroski Susan P. McCormick USDA, ARS, National Center for Agricultural Utilization Research Peoria, IL 61604 June 10, 1992 vii CONTENTS ANTIBIOTICS Polyketide Synthetases: Enzyme Complexes and Multifunctional Proteins Directing the Biosynthesis of Bacterial Metabolites from Fatty Acids. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 . . . . . . . . . . .

SECONDARY METABOLITES Book

SECONDARY METABOLITES


  • Author : Dr. Preethi Kathirvel
  • Publisher : DARSHAN PUBLISHERS
  • Release Date : 2021-01-25
  • Genre: Science
  • Pages : 148
  • ISBN 10 : 9788193264515

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SECONDARY METABOLITES Excerpt :

Secondary metabolites are organic compounds that are not directly involved in the normal growth, development, or reproduction of an organism. The secondary metabolites are produced majorly by plants and are called phytochemicals, also by microbes such as bacteria, fungi, algae and so on. These secondary metabolites plays a major role in defensive mechanism in plants, as well as its components are used in food industry, pharmaceuticals and so on. The applications and sources of each secondary metabolite is clearly discussed. We are very much thankful for the publisher who readily accepts and publish this subject. Also the author is very much thankful to her research team Mridul Umesh, Thazeem Basheer, Poorna Chandrika Sabapathy, Sabarinathan Devaraj and Sathishkumar Swamiappan for contributing their help and support for this work. The next edition of this book will more precisely discuss on the extraction and purification of the secondary metabolites.

Phytochemical And Biological Studies Of Exudates From Scilla Nervosa Book

Phytochemical And Biological Studies Of Exudates From Scilla Nervosa


  • Author : Samson Oluwaseyi Famuyiwa
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2013
  • Genre: Uncategoriezed
  • Pages : 132
  • ISBN 10 : 3659473146

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Phytochemical And Biological Studies Of Exudates From Scilla Nervosa Excerpt :

Nature is an inexhaustible source of organic molecules many of which possess important biological activities. Plants are considered to be a repository of a large number of these molecules. The study of plants for their secondary metabolites will continue to be an important and relevant area of research activity globally for the discovery of novel compounds that may have therapeutic and biological properties that are beneficial to man existence. The book describes the isolation, purification, characterization and biological activities of secondary metabolites from a medicinal plant.

Marine Phenolics Book

Marine Phenolics


  • Author : Herminia Domínguez
  • Publisher : Unknown
  • Release Date : 2021
  • Genre: Uncategoriezed
  • Pages : 232
  • ISBN 10 : 3036502653

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Marine Phenolics Excerpt :

Phenolic compounds are an extremely diverse class of ubiquitous secondary metabolites produced by a variety of organisms playing different biological roles. They have numerous types of demonstrated bioactivities, including antioxidant, antimicrobial, anti-inflammatory, antitumoral, immunomodulator, neuroprotective, cardioprotective, and antidiabetic activities. Marine organisms produce a vast collection of unique phenolic structures, some of them not found in terrestrial habitats. Progress in different aspects is rapidly advancing, and this Special Issue will provide updated information and recent studies on marine phenolics. Specially, this issue is focused on their chemical characterization, elucidation of their structures, evaluation of their biological properties and mechanisms of action, efficient extraction and purification technologies, development of value-added applications, as well as formulation of novel products.

Discovery of Novel Natural Products with Therapeutic Potential Book

Discovery of Novel Natural Products with Therapeutic Potential


  • Author : Vincent P. Gullo
  • Publisher : Newnes
  • Release Date : 2013-10-22
  • Genre: Science
  • Pages : 544
  • ISBN 10 : 9781483292137

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Discovery of Novel Natural Products with Therapeutic Potential Excerpt :

Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sources of natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

Secondary Metabolites Book

Secondary Metabolites


  • Author : Ramasamy Vijayakumar
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-09-05
  • Genre: Science
  • Pages : 148
  • ISBN 10 : 9781789236422

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Secondary Metabolites Excerpt :

This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.

Marine Phenolics Book

Marine Phenolics


  • Author : Herminia Domínguez
  • Publisher : MDPI
  • Release Date : 2021-08-16
  • Genre: Science
  • Pages : 232
  • ISBN 10 : 9783036502649

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Marine Phenolics Excerpt :

Phenolic compounds are an extremely diverse class of ubiquitous secondary metabolites produced by a variety of organisms playing different biological roles. They have numerous types of demonstrated bioactivities, including antioxidant, antimicrobial, anti-inflammatory, antitumoral, immunomodulator, neuroprotective, cardioprotective, and antidiabetic activities. Marine organisms produce a vast collection of unique phenolic structures, some of them not found in terrestrial habitats. Progress in different aspects is rapidly advancing, and this Special Issue will provide updated information and recent studies on marine phenolics. Specially, this issue is focused on their chemical characterization, elucidation of their structures, evaluation of their biological properties and mechanisms of action, efficient extraction and purification technologies, development of value-added applications, as well as formulation of novel products.

Fungal Biotechnology Book

Fungal Biotechnology


  • Author : Sunil K. Deshmukh
  • Publisher : CRC Press
  • Release Date : 2022-08-18
  • Genre: Medical
  • Pages : 450
  • ISBN 10 : 9781000653779

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Fungal Biotechnology Excerpt :

Traditional studies in mycology mainly deal with damage caused by fungi, for instance, diseases of plants, animal ailments, air-borne pathogens, decomposition of wood and production of mycotoxins in food. Applied mycology focuses on the fermentation of foods (flours, bakery products, cheese and others) and production of fermented products (wine, beer and spirit). Further value-added approaches show the significance of fungi in the production of bioactive metabolites and pharmaceuticals used in the treatment of human diseases, including cancer, and plant diseases (e.g. pest control). Due to a dependence on fossil resources, production of bio-renewable merchandise gained importance and fungi serve as potential biological agents in sustaining global economy. Recent developments in mycology revealed their significance in the fields of advanced research, in particular building materials, packaging resources, electronic devises and leather-like goods. In addition, fungi possess several qualities to degrade non-biodegradable compounds in the ecosystem and assist in sustainable waste bioremediation. This book covers the current biotechnological advances and bio-prospect potential of fungi. Fungal biopolymers possess various applications, including prebiotics, therapeutics, immunoceuticals, drug-discovery and drug-delivery. Fungal bioactive metabolites have several implications beyond antibiotics, such as volatiles, biofuels, nematicides and pigments. They also serve as prospective tools in the production of nanoparticles of medicinal, nutritional and industrial significance. In view of environmental protection, fungal activity and products aid in bioremediation via degradation of xenobiotics and solid wastes. Fungi can produce agriculturally compatible metabolites to enhance plant production. Knowledge on fungal genomics facilitates the gene manipulation towards biotechnological applications (disease diagnosis, pathogen detection, gene expression and mutualistic interaction

Studies in Natural Products Chemistry Book

Studies in Natural Products Chemistry


  • Author : Atta-ur-Rahman
  • Publisher : Elsevier
  • Release Date : 2020-08-01
  • Genre: Science
  • Pages : 440
  • ISBN 10 : 9780128179086

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Studies in Natural Products Chemistry Excerpt :

Studies in Natural Products Chemistry, Volume 66 covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in new drug development for the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Secondary Metabolism in Model Systems Book

Secondary Metabolism in Model Systems


  • Author : John Romeo
  • Publisher : Elsevier
  • Release Date : 2004-07-14
  • Genre: Science
  • Pages : 280
  • ISBN 10 : 0080474330

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Secondary Metabolism in Model Systems Excerpt :

The chapters presented in Secondary Metabolism in Model Systems are a microcosm of what the recent completion, or near completion, of various genome projects are enabling biochemists to understand not only about control and regulation of secondary metabolism, and how various pathways relate to each other, but also about its relation to primary metabolism. A major paradigm shift is occurring in the way researchers need to view "secondary" metabolism in the future.It is also clear that model systems, such as the ones discussed in the symposium, are providing new information and insight almost faster than researchers can process it! The volumes in this series contain articles on developing topics of interest to scientists, students and individuals interested in recent developments in the biochemistry, chemistry and molecular biology of plants. An excellent series volume covering the advances in understanding of gene functions, a high profile area of research due to recent genome projects This book provides essential information on new model systems available to biochemists The chapters in this volume are based on the papers presented in the symposium entitled "Secondary Metabolism in Model Systems"

Genetic Engineering of Plant Secondary Metabolism Book

Genetic Engineering of Plant Secondary Metabolism


  • Author : Brian E. Ellis
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 368
  • ISBN 10 : 9781461525448

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Genetic Engineering of Plant Secondary Metabolism Excerpt :

In this volume of Recent Advances in Phytochmistry you will find a record of the pioneering attempts of plant biochemists and molecular biologists to modify the patterns of secondary metabolism in plants, as presented at the 33rd annual meeting of the Phytochemical Society of North America, in Asilomar, California, on June 27 -July I, 1993. The studies described here represent a marriage of the newest of technologies with one of the oldest human activities, exploitation of plant chemistry. They also represent the beginning of a new era of phytochemical research, an era that will undoubtedly begin to provide answers to some of the long-standing questions that have absorbed plant biochemists for the past century. There is, for instance, a common deflating experience to which every worker in the area of plant secondary metabolism can probably relate. After hearing about the latest research findings regarding some aspect of remarkable compound "X", someone in the audience finally directs the inevitable question at the hapless speaker. "Tell me, is anything known as to the biological role of compound "X" in the plant?" The answer, in most cases, must be "essentially nothing"! This is a frustrating scenario for both the speaker and the audience, since the very fact that a complex biosynthetic pathway remains encoded in a plant genome points to an associated selective advantage. The problem is that establishing the nature and scale of that advantage is a very complex task.

Seaweeds Secondary Metabolites Book

Seaweeds Secondary Metabolites


  • Author : Diana Cláudia Pinto
  • Publisher : MDPI
  • Release Date : 2020-02-21
  • Genre: Medical
  • Pages : 320
  • ISBN 10 : 9783039283002

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Seaweeds Secondary Metabolites Excerpt :

Seaweeds are recognized as highly nutritious, and their use in gastronomy is increasing. Their health benefits and their potential to prevent several diseases have also been established. In this Special Issue several health effects are discussed, with more emphasis on their antitumor activity and potential use to treat Alzheimer’s disease. The key bioactive metabolites, from which phlorotannins can be highlighted, are presented, as well as some important in vivo studies. Altogether, the chapters provide in-depth information about the biological activities of seaweed metabolites, contributing to elucidate the health effects of seaweed.