Recent Advances in iPSC Disease Modeling  Volume 1 Book

Recent Advances in iPSC Disease Modeling Volume 1


  • Author : ALEXANDER BIRBRAIR
  • Publisher : Academic Press
  • Release Date : 2020-07-16
  • Genre: Science
  • Pages : 320
  • ISBN 10 : 9780128232699

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Recent Advances in iPSC Disease Modeling Volume 1 Excerpt :

Recent Advances in iPSC Disease Modeling, Volume 1 addresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics Covers the following diseases: severe congenital neutropenia, sickle cell and Diamond-Blackfan anemias, muscular dystrophies, Bernard-Soulier syndrome, familial hypercholesterolemia type II A, Werner syndrome, lysosomal storage diseases, and more Contains description of cutting-edge research on the development of disease-specific human pluripotent stem cells. These cells allow us to study cellular and molecular processes involved in several human diseases

Novel Concepts in iPSC Disease Modeling Book

Novel Concepts in iPSC Disease Modeling


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2022-01-25
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780128238837

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Novel Concepts in iPSC Disease Modeling Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson’s disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson’s disease, graft vs. host disease, and much more Contributed by world-renown experts in the field

iPSCs in Tissue Engineering Book

iPSCs in Tissue Engineering


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-08-12
  • Genre: Science
  • Pages : 430
  • ISBN 10 : 9780128241905

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iPSCs in Tissue Engineering Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs in Tissue Engineering, Volume 11 addresses how induced pluripotent stem cells (iPSCs) are being used to advance tissue engineering. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This book will address the advances in research of how iPSCs are being used for the generation of different tissues and organs such as the lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and tissue engineering and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics Covers the engineering of the following organs: lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and more Is contributed from stem cell leaders around the world

iPSCs   State of the Science Book

iPSCs State of the Science


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2022-01-09
  • Genre: Science
  • Pages : 316
  • ISBN 10 : 9780323856454

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iPSCs State of the Science Excerpt :

iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived from amniotic fluid, oral tissue derived iPSCs, muse cells, postmortem tissue, and much more Contributed by world-renowned experts in the field

Medical Applications of iPS Cells Book

Medical Applications of iPS Cells


  • Author : Haruhisa Inoue
  • Publisher : Springer
  • Release Date : 2019-04-01
  • Genre: Medical
  • Pages : 190
  • ISBN 10 : 9789811336720

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Medical Applications of iPS Cells Excerpt :

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.

IPSCs for Studying Infectious Diseases Book

IPSCs for Studying Infectious Diseases


  • Author : Alexander Birbrair
  • Publisher : Elsevier
  • Release Date : 2021-06-23
  • Genre: Science
  • Pages : 332
  • ISBN 10 : 9780128238080

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IPSCs for Studying Infectious Diseases Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Studying Infectious Diseases, Volume 8 addresses how important induced pluripotent stems cells are and how can they can help treat certain infectious diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different infectious diseases, such as corona virus, coxsackievirus, salmonella infection, influenza virus and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers salmonella infection, hepatotropic pathogen infection, corona virus, influenza virus, and more Contributed by world-renown experts in the field

Recent Advances in IPSC Technology  Volume 5 Book

Recent Advances in IPSC Technology Volume 5


  • Author : Alexander Birbrair
  • Publisher : Elsevier
  • Release Date : 2021-04-21
  • Genre: Science
  • Pages : 334
  • ISBN 10 : 9780128222317

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Recent Advances in IPSC Technology Volume 5 Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes different technologies and strategies to use iPSCs for biological and clinical benefit. In recent years, remarkable progress has been made in the obtention of iPSCs and their differentiation into several cell types, tissues, and organs using state-of-the-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. This volume will cover hot topics in the iPSC field, such as iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the noncoding genome, modeling of blood-brain barrier with iPSCs, mathematical modeling of iPSCs, iPSCs to study human brain evolution, selfrenewal in iPSCs, differences and similarities between iPSCs and embryonic stem cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics. Covers the following topics: iPSCs for modeling the cardiovascular toxicities of anticancer therapies, iPSC differentiation through the lens of the non-coding genome, modeling of blood-brain barrier with iPSCs, mathematical modelling of iPSCs, iPSCs to study human brain evolution, self-renewal in iPSCs, differences and

Current Progress in iPSC Disease Modeling Book

Current Progress in iPSC Disease Modeling


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-11-26
  • Genre: Science
  • Pages : 324
  • ISBN 10 : 9780323856430

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Current Progress in iPSC Disease Modeling Excerpt :

Current Progress in iPSC Disease Modeling, Volume Fourteen in the Advances in Stem Cell Biology series, is a timely and expansive collection of information and new discoveries in the field. This new volume addresses advances in research on how induced pluripotent stem cells are used for the creation of new tissues and organs. The creation of iPSC technology allowed the development of disease-specific human pluripotent stem cells. These cells allow researchers to study questions once impossible for some human diseases. This volume addresses iPSCs for vascular tissue engineering, bioprinting, derived lung organoids for pulmonary disorders, skeletal muscle engineering, human kidney organoids, and more. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers advances in research on how induced pluripotent stem cells are used to create new tissues/organs Contributed by world-renowned experts in the field

Cells and Materials for Disease Modeling and Regenerative Medicine Book

Cells and Materials for Disease Modeling and Regenerative Medicine


  • Author : Ander Abarrategi
  • Publisher : MDPI
  • Release Date : 2021-05-05
  • Genre: Science
  • Pages : 270
  • ISBN 10 : 9783036502625

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Cells and Materials for Disease Modeling and Regenerative Medicine Excerpt :

Materials science and engineering are strongly developing tools with increasing impact in the biotechnological and biomedical areas. Interestingly, research in molecular and cellular biology is often at the core of the design and development of materials-based approaches, providing biological rationale. Focused on research relying on biology–materials interaction, IJMS launched a Special Issue named “Cells and Materials for Disease Modeling and Regenerative Medicine”. The aim of the Special Issue was to generate a compilation of in vitro and in vivo strategies based on cell–material interactions. This book compiles the papers published in that Special Issue and includes a selection of six original scientific experimental articles and six comprehensive reviews. We are convinced that this collection of articles shows representative examples of the state of the art in the field, unveiling the relevance of materials research in generating new regenerative medicine and disease modeling approaches.

Current Topics in iPSCs Technology Book

Current Topics in iPSCs Technology


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2022-01-18
  • Genre: Science
  • Pages : 636
  • ISBN 10 : 9780323983983

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Current Topics in iPSCs Technology Excerpt :

Current Topics in iPSCs provides a deep analysis of the underlying fundamentals that support short and mid-term developments and milestones in the business of mesenchymal stem cell therapies. This volume explores the next frontier of MSC therapies and how the transformational potential of therapeutic adult cells will be realised in all therapy areas. The impacts of clinical and economic benefits are dissected throughout each of the chapters. Written by thought leaders in the field for those curious about the interface of science and business. Explores the strategy at the forefront of the science of mesenchymal stem cells Provides an overview of all therapy areas where MSC and MSC-derived products can be used therapeutically Depicts transformational changes in healthcare that enable the implementation of MSC-powered technology platforms

iPSC Derived Progenitors Book

iPSC Derived Progenitors


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-11-10
  • Genre: Science
  • Pages : 318
  • ISBN 10 : 9780323900737

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iPSC Derived Progenitors Excerpt :

iPSC Derived Progenitors, Volume Thirteen in the Advances in Stem Cell Biology series is a timely collection of information and new discoveries in the field of stem cell biology. The book addresses the importance of induced pluripotent stems cells and how can they be differentiated into different progenitors. Progenitors cells are often the first-step to making more differentiating cell types. This volume addresses iPSCs derived from bone, dental pulp, craniofacial, neural stem cells, otic, cardiac, and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine, organ transplantation, and is contributed by world-renowned authors. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers how iPSCs can be differentiated into different progenitors Contributed by world renowned experts in the field

Pluripotent Stem Cells Book

Pluripotent Stem Cells


  • Author : Minoru Tomizawa
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-07-20
  • Genre: Science
  • Pages : 532
  • ISBN 10 : 9789535124719

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Pluripotent Stem Cells Excerpt :

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

Principles of Regenerative Medicine Book
Score: 5
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Principles of Regenerative Medicine


  • Author : Anthony Atala
  • Publisher : Academic Press
  • Release Date : 2010-12-16
  • Genre: Science
  • Pages : 1202
  • ISBN 10 : 0123814235

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Principles of Regenerative Medicine Excerpt :

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench to Bedside Book

Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench to Bedside


  • Author : Kuldip S. Sidhu
  • Publisher : Bentham Science Publishers
  • Release Date : 2012
  • Genre: Science
  • Pages : 237
  • ISBN 10 : 9781608052899

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Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench to Bedside Excerpt :

"Pluripotent stem cells have garnered tremendous interest in recent years, which is primarily driven by the hope of finding a cure for several debilitating human diseases. Cell transplantation (regeneratve medicine) offers considerable therapeutic potentia"

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension Book

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension


  • Author : Toshio Nakanishi
  • Publisher : Springer Nature
  • Release Date : 2020-02-28
  • Genre: Medical
  • Pages : 405
  • ISBN 10 : 9789811511851

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Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension Excerpt :

This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.