Scientific Principles of Adipose Stem Cells Book

Scientific Principles of Adipose Stem Cells


  • Author : Lauren Kokai
  • Publisher : Elsevier
  • Release Date : 2021-08-25
  • Genre: Science
  • Pages : 484
  • ISBN 10 : 9780128193761

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Scientific Principles of Adipose Stem Cells Excerpt :

Scientific Principles of Adipose Stem Cells provides readers with in depth and expert knowledge on adipose stem cells in regards to developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties and clinical insights into applications in regenerative medicine. Written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and are seeking advanced information on adipose stem cells. Topics covered include basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, additional sections are devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications. Given the broad applications for which ASCs are used, as well as the interest in basic ASC science, Scientific Principles of Adipose Stem Cells transcends an audience of plastic surgeons and provides valuable and expert knowledge in developmental and cell biology appealing to basic scientists in a variety of fields. Information on cell manufacturing and commercialization, FDA regulations and ASC exosomes which appeal to those working in industry and applications of ASCs in cutting edge tissue engineering applications such as microphysiologic systems and/or bioreactors, are also included. These new technologies have important applications in drug discovery and for studying genetically modified ASCs.

Scientific Principles of Adipose Stem Cells Book

Scientific Principles of Adipose Stem Cells


  • Author : Lauren Kokai
  • Publisher : Academic Press
  • Release Date : 2021-09-01
  • Genre: Science
  • Pages : 484
  • ISBN 10 : 9780128193778

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Scientific Principles of Adipose Stem Cells Excerpt :

Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells. Coverage of basic adipose stem cell developmental biology (maturation process during embryogenesis) and mechanisms of regulating self-renewal and activation in the stem cell niche Includes important methods for isolation and characterizing ASCs, as well as known data any impact of human demographics (age, sex, BMI) on ASC phenotype An entire section dedicated to ASC biology, additional sections will be devoted to ASCs for stem cell therapy and regenerative medicine, as well as ASCs in tissue engineering applications

Progenitor and Stem Cell Technologies and Therapies Book

Progenitor and Stem Cell Technologies and Therapies


  • Author : Anthony Atala
  • Publisher : Elsevier
  • Release Date : 2012-03-15
  • Genre: Medical
  • Pages : 568
  • ISBN 10 : 9780857096074

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Progenitor and Stem Cell Technologies and Therapies Excerpt :

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. Reviews the range of progenitor and stem cells available and outlines their therapeutic application Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies

Adipose Derived Stem Cells Book

Adipose Derived Stem Cells


  • Author : Jeffrey M. Gimble
  • Publisher : Humana Press
  • Release Date : 2011-08-24
  • Genre: Science
  • Pages : 474
  • ISBN 10 : 1617379611

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Adipose Derived Stem Cells Excerpt :

During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.

Principles of Regenerative Medicine Book
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Principles of Regenerative Medicine


  • Author : Anthony Atala
  • Publisher : Academic Press
  • Release Date : 2010-12-16
  • Genre: Science
  • Pages : 1202
  • ISBN 10 : 0123814235

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Principles of Regenerative Medicine Excerpt :

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Biomaterials and Stem Cells in Regenerative Medicine Book

Biomaterials and Stem Cells in Regenerative Medicine


  • Author : Murugan Ramalingam
  • Publisher : CRC Press
  • Release Date : 2012-07-03
  • Genre: Medical
  • Pages : 567
  • ISBN 10 : 9781439879252

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Biomaterials and Stem Cells in Regenerative Medicine Excerpt :

Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It covers the basic science involved in structure and properties, techniques and technological innovations in processing and characterization, and applications of biomaterials and stem cells. Topics include: Polymeric systems for stem cell delivery The potential of membranes and porous scaffolds in tissue repair, including myocardial, periodontal, ophthalmic, and bone tissues The optimization of the interaction between stem cells and biomaterial substrates The source and nature of stem cells for tissue engineering applications The clinical translation of stem cell–based tissue engineering for regenerative medicine From fundamental principles to recent advances at the macro, micro, nano, and molecular scales, the book brings together current knowledge on biomaterials and stem cells in the context of regenerative medicine. It also stimulates discussion about future research directions. This unique book offers a valuable benchmark for the current status of clinically relevant research and development in stem cells and regenerative medicine. It bridges the gaps in experimental approaches and understanding among the materials science and engineering, biological sciences, and biomedical science and engineering communities, making it a valuable reference for graduate students, researchers, a

Greenfield s Surgery Book

Greenfield s Surgery


  • Author : Michael W. Mulholland
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2016-11-15
  • Genre: Medical
  • Pages : 8237
  • ISBN 10 : 9781469890029

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Greenfield s Surgery Excerpt :

Revised, updated, and enhanced from cover to cover, the Sixth Edition of Greenfield’s Surgery: Scientific Principles and Practice remains the gold standard text in the field of surgery. It reflects surgery’s rapid changes, new technologies, and innovative techniques, integrating new scientific knowledge with evolving changes in surgical care. Updates to this edition include new editors and contributors, and a greatly enhanced visual presentation. Balancing scientific advances with clinical practice, Greenfield’s Surgery is an invaluable resource for today’s residents and practicing surgeons.

Stem Cells and Biomaterials for Regenerative Medicine Book

Stem Cells and Biomaterials for Regenerative Medicine


  • Author : Marek J. Los
  • Publisher : Academic Press
  • Release Date : 2018-11-07
  • Genre: Science
  • Pages : 249
  • ISBN 10 : 9780128122785

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Stem Cells and Biomaterials for Regenerative Medicine Excerpt :

Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science—medicine, the latest technology, and clinical economics—the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more. Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. Arms readers with key information on tissue engineering, artificial organs and biomaterials, while using broadly accessible language Provides broad introduction to, and examples of, various types of stem cells, core concepts of regenerative medicine, biomaterials, nanotechnology and nanomaterials, somatic cell transdyferentiation, and more Edited and authored by researchers with expertise in regenerative medicine, (cancer) stem cells, biomaterials, genetics and nanomaterials

Adipose Stem Cells and Regenerative Medicine Book

Adipose Stem Cells and Regenerative Medicine


  • Author : Yves-Gerard Illouz
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-09-07
  • Genre: Medical
  • Pages : 278
  • ISBN 10 : 3642200125

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Adipose Stem Cells and Regenerative Medicine Excerpt :

The therapeutic potential of the use of adipose stem cells in regenerative medicine has been increasingly recognized, and in recent years concrete clinical benefits have accrued as these cells have been explored for a variety of applications. This readable and informative textbook tracks the progress that has been made in this fascinating new area of biomedicine. All aspects of the subject are considered, with particular attention to adipose cell biology, adipose tissue engineering strategies, and the diverse clinical applications of adipose stem cells. Funding issues, industrial approaches, regulatory challenges, and future directions are also examined. The two editors have vast experience in the field and have chosen leading experts from different countries to write on each topic. This book will excite the interest of all researchers, clinicians, and students wishing to gain an in-depth understanding of adipose stem cells and their flourishing role in regenerative medicine.

Principles of Tissue Engineering Book

Principles of Tissue Engineering


  • Author : Robert Lanza
  • Publisher : Academic Press
  • Release Date : 2020-03-26
  • Genre: Business & Economics
  • Pages : 1678
  • ISBN 10 : 9780128214015

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Principles of Tissue Engineering Excerpt :

Now in its fifth edition, Principles of Tissue Engineering has been the definite resource in the field of tissue engineering for more than a decade. The fifth edition provides an update on this rapidly progressing field, combining the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation by the world’s experts of what is currently known about each specific organ system. As in previous editions, this book creates a comprehensive work that strikes a balance among the diversity of subjects that are related to tissue engineering, including biology, chemistry, material science, and engineering, among others, while also emphasizing those research areas that are likely to be of clinical value in the future. This edition includes greatly expanded focus on stem cells, including induced pluripotent stem (iPS) cells, stem cell niches, and blood components from stem cells. This research has already produced applications in disease modeling, toxicity testing, drug development, and clinical therapies. This up-to-date coverage of stem cell biology and the application of tissue-engineering techniques for food production – is complemented by a series of new and updated chapters on recent clinical experience in applying tissue engineering, as well as a new section on the emerging technologies in the field. Organized into twenty-three parts, covering the basics of tissue growth and development, approaches to tissue and organ design, and a summary of current knowledge by organ system Introduces a new section and chapters on emerging technologies in the field Full-color presentation throughout

Scientific Advances in Reconstructive Urology and Tissue Engineering Book

Scientific Advances in Reconstructive Urology and Tissue Engineering


  • Author : Matthias D. Hofer
  • Publisher : Academic Press
  • Release Date : 2022-03-31
  • Genre: Science
  • Pages : 316
  • ISBN 10 : 9780323915205

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Scientific Advances in Reconstructive Urology and Tissue Engineering Excerpt :

Scientific Advances in Reconstructive Urology and Tissue Engineering is a comprehensive overview of reconstructive urology that spans male and female, pediatric, neuro-urology and trauma. Traditionally, this field has been focused solely on surgical principles with little attention to basic and translational research. However, recent advances in acellular matrices, scaffolds, stem cells and tissue engineering have changed this focus. This publication is the perfect bridge and definitive tome of the advances that will move the translational and basic science of reconstructive urology forward and allow readers to implement the findings in clinical practice. Through the use of both current case studies and future implications, the content bridges the gap from bench to bedside making it the perfect reference for translational benign urology researchers who wish to move the field of reconstructive surgery forward. Includes real-world applications of current research to help readers get rapidly up-to-speed on which research results are appropriate for immediate implementation Presents the underlying mechanism of urologic disease processes pertinent to reconstructive urology for comprehensive understanding within the field Provides independent guidance to manage specific clinical conditions while also presenting approaches that are applicable to all conditions

Advanced Techniques in Bone Regeneration Book

Advanced Techniques in Bone Regeneration


  • Author : Alessandro Rozim Zorzi
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-08-31
  • Genre: Medical
  • Pages : 388
  • ISBN 10 : 9789535125389

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Advanced Techniques in Bone Regeneration Excerpt :

Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

Stem Cells Book

Stem Cells


  • Author : Ariff Bongso
  • Publisher : World Scientific
  • Release Date : 2011
  • Genre: Science
  • Pages : 721
  • ISBN 10 : 9789814289382

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Stem Cells Excerpt :

Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.

Stem Cell Bioprocessing and Manufacturing Book

Stem Cell Bioprocessing and Manufacturing


  • Author : Joaquim M. S. Cabral
  • Publisher : MDPI
  • Release Date : 2021-01-20
  • Genre: Science
  • Pages : 170
  • ISBN 10 : 9783039430383

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Stem Cell Bioprocessing and Manufacturing Excerpt :

The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the potential, and early products have shown the power of such therapies, there is an immediate and long-term need for expertise with the necessary skills to face the engineering and life science challenges before the predicted benefits in human healthcare can be realized. Specifically, there is a need for the development of bioprocess technology for the successful transfer of laboratory-based practice of stem cell and tissue culture to the clinic as therapeutics through the application of engineering principles and practices. This Special Issue of Bioengineering on Stem Cell Bioprocessing and Manufacturing addresses the central role in defining the engineering sciences of cell-based therapies, by bringing together contributions from worldwide experts on stem cell biology and engineering, bioreactor design and bioprocess development, scale-up, and manufacturing of stem cell-based therapies.

Human Embryonic Stem Cells Book

Human Embryonic Stem Cells


  • Author : Arlene Chiu
  • Publisher : Springer Science & Business Media
  • Release Date : 2003-08-01
  • Genre: Science
  • Pages : 455
  • ISBN 10 : 9781592594238

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Human Embryonic Stem Cells Excerpt :

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.