Secondary Findings in Genomic Research Book

Secondary Findings in Genomic Research


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-02-29
  • Genre: Medical
  • Pages : 244
  • ISBN 10 : 9780128167489

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Secondary Findings in Genomic Research Excerpt :

Secondary Findings in Genomic Research offers a single, highly accessible resource on interpreting, managing and disclosing secondary findings in genomic research. With chapters written by experts in the field, this book is the first to concisely explain the ethical and practical issues raised by secondary genomics findings for a multi and interdisciplinary audience of genomic researchers, translational scientists, clinicians, medical students, genetic counselors, ethicists, legal experts and law students, public policy specialists and regulators. Contributors from Europe, North America, and Asia effectively synthesize perspectives from a spectrum of different scientific, societal, and global contexts, and offer pragmatic approaches to a range of topics, including oversight, governance and policy surrounding secondary genomic results, criteria for identifying results for return, communication and consent, stakeholders’ attitudes and perspectives, disclosing results, and clinical, patient-centered protocols. Thoroughly addresses the scientific, ethical, practical and clinical issues raised by secondary findings resulting from genomic research, including active debate and challenges in the field Provides researchers, clinicians, regulators, and stakeholders with a holistic, interdisciplinary approach to interpreting, managing and disclosing secondary findings Brings together expert analysis from scholars across Europe, North America, and Asia representing a wide variety of scientific and societal contexts

Secondary Findings in Genomic Research Book

Secondary Findings in Genomic Research


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-03-18
  • Genre: Medical
  • Pages : 244
  • ISBN 10 : 9780128165492

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Secondary Findings in Genomic Research Excerpt :

Secondary Findings in Genomic Research offers a single, highly accessible resource on interpreting, managing and disclosing secondary findings in genomic research. With chapters written by experts in the field, this book is the first to concisely explain the ethical and practical issues raised by secondary genomics findings for a multi and interdisciplinary audience of genomic researchers, translational scientists, clinicians, medical students, genetic counselors, ethicists, legal experts and law students, public policy specialists and regulators. Contributors from Europe, North America, and Asia effectively synthesize perspectives from a spectrum of different scientific, societal, and global contexts, and offer pragmatic approaches to a range of topics, including oversight, governance and policy surrounding secondary genomic results, criteria for identifying results for return, communication and consent, stakeholders' attitudes and perspectives, disclosing results, and clinical, patient-centered protocols. Thoroughly addresses the scientific, ethical, practical and clinical issues raised by secondary findings resulting from genomic research, including active debate and challenges in the field Provides researchers, clinicians, regulators, and stakeholders with a holistic, interdisciplinary approach to interpreting, managing and disclosing secondary findings Brings together expert analysis from scholars across Europe, North America, and Asia representing a wide variety of scientific and societal contexts

Clinical Genome Sequencing Book

Clinical Genome Sequencing


  • Author : Aad Tibben
  • Publisher : Academic Press
  • Release Date : 2019-03-30
  • Genre: Medical
  • Pages : 258
  • ISBN 10 : 9780128133361

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Clinical Genome Sequencing Excerpt :

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine. Features contributions from leading international researchers and practitioners versed in the psychosocial dimensions of genomic medicine implementation Presents clinical case studies that support concept illustration, making this an invaluable reference for students, researchers, and clinicians looking for practical guidance in this important and multifaceted topic area Details the current state of genomic testing, expectations of genome sequencing, patient consent, patient responses to sequencing data, uncertainties in genome sequencing, direct-to-consumer genome sequencing, and more

Implementing and Evaluating Genomic Screening Programs in Health Care Systems Book

Implementing and Evaluating Genomic Screening Programs in Health Care Systems


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2018-06-16
  • Genre: Medical
  • Pages : 151
  • ISBN 10 : 9780309473415

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Implementing and Evaluating Genomic Screening Programs in Health Care Systems Excerpt :

Genomic applications are being integrated into a broad range of clinical and research activities at health care systems across the United States. This trend can be attributed to a variety of factors, including the declining cost of genome sequencing and the potential for improving health outcomes and cutting the costs of care. The goals of these genomics-based programs may be to identify individuals with clinically actionable variants as a way of preventing disease, providing diagnoses for patients with rare diseases, and advancing research on genetic contributions to health and disease. Of particular interest are genomics- based screening programs, which will, in this publication, be clinical screening programs that examine genes or variants in unselected populations in order to identify individuals who are at an increased risk for a particular health concern (e.g., diseases, adverse drug outcomes) and who might benefit from clinical interventions. On November 1, 2017, the National Academies of Sciences, Engineering, and Medicine hosted a public workshop to explore the challenges and opportunities associated with integrating genomics-based screening programs into health care systems. This workshop was developed as a way to explore the challenges and opportunities associated with integrating genomics-based programs in health care systems in the areas of evidence collection, sustainability, data sharing, infrastructure, and equity of access. This publication summarizes the presentations and discussions from the workshop.

Returning Individual Research Results to Participants Book

Returning Individual Research Results to Participants


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2018-09-23
  • Genre: Medical
  • Pages : 399
  • ISBN 10 : 9780309475174

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Returning Individual Research Results to Participants Excerpt :

When is it appropriate to return individual research results to participants? The immense interest in this question has been fostered by the growing movement toward greater transparency and participant engagement in the research enterprise. Yet, the risks of returning individual research resultsâ€"such as results with unknown validityâ€"and the associated burdens on the research enterprise are competing considerations. Returning Individual Research Results to Participants reviews the current evidence on the benefits, harms, and costs of returning individual research results, while also considering the ethical, social, operational, and regulatory aspects of the practice. This report includes 12 recommendations directed to various stakeholdersâ€"investigators, sponsors, research institutions, institutional review boards (IRBs), regulators, and participantsâ€"and are designed to help (1) support decision making regarding the return of results on a study-by-study basis, (2) promote high-quality individual research results, (3) foster participant understanding of individual research results, and (4) revise and harmonize current regulations.

Medical and Health Genomics Book

Medical and Health Genomics


  • Author : Dhavendra Kumar
  • Publisher : Academic Press
  • Release Date : 2016-06-04
  • Genre: Science
  • Pages : 358
  • ISBN 10 : 9780127999227

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Medical and Health Genomics Excerpt :

Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

A Guide to Genetic Counseling Book

A Guide to Genetic Counseling


  • Author : Wendy R. Uhlmann
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-20
  • Genre: Medical
  • Pages : 644
  • ISBN 10 : 9781118210536

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A Guide to Genetic Counseling Excerpt :

The first book devoted exclusively to the principles and practice of genetic counseling—now in a new edition First published in 1998, A Guide to Genetic Counseling quickly became a bestselling and widely recognized text, used nationally and internationally in genetic counseling training programs. Now in its eagerly anticipated Second Edition, it provides a thoroughly revised and comprehensive overview of genetic counseling, focusing on the components, theoretical framework, and unique approach to patient care that are the basis of this profession. The book defines the core competencies and covers the genetic counseling process from case initiation to completion—in addition to addressing global professional issues—with an emphasis on describing fundamental principles and practices. Chapters are written by leaders in the field of genetic counseling and are organized to facilitate academic instruction and skill attainment. They provide the most up-to-date coverage of: The history and practice of genetic counseling Family history Interviewing Case preparation and management Psychosocial counseling Patient education Risk communication and decision-making Medical genetics evaluation Understanding genetic testing Medical documentation Multicultural counseling Ethical and legal issues Student supervision Genetic counseling research Professional development Genetics education and outreach Evolving roles and expanding opportunities Case examples A Guide to Genetic Counseling, Second Edition belongs on the syllabi of all medical and human genetics and genetic counseling training programs. It is an indispensable reference for both students and healthcare professionals working with patients who have or are at risk for genetic conditions.

Anticipate and Communicate Book

Anticipate and Communicate


  • Author : Presidential Commission for the Study of Bioethical Issues
  • Publisher : CreateSpace
  • Release Date : 2015-03-11
  • Genre: Medical
  • Pages : 156
  • ISBN 10 : 1508807647

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Anticipate and Communicate Excerpt :

Anticipate and Communicate is the Bioethics Commission's sixth major report. In this report the Bioethics Commission offers specific recommendations for the management of incidental and secondary findings in clinical, research and direct-to-consumer settings. Emerging medical technologies, changing cost structures, and evolving medical practice make the likelihood of discovering incidental and secondary findings across contexts a growing certainty. Such findings can be lifesaving, but also can lead to uncertainty and distress if they are unexpected or identify conditions for which no effective treatment is available.

Modern Medical Genetics and Genomics Book

Modern Medical Genetics and Genomics


  • Author : Israel Gomy
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-12-18
  • Genre: Medical
  • Pages : 106
  • ISBN 10 : 9781839681424

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Modern Medical Genetics and Genomics Excerpt :

The field of medical genetics and genomics has been constantly revolutionized by new breakthroughs, which bring more knowledge into the etiology and help improve the health care of individuals with either rare or common diseases. Nevertheless, as technologies evolve, novel challenges emerge, both technically and ethically, so they must be prudentially addressed. Among the myriad applications of genomics in medicine, this book depicts a glimpse of the advances achieved that have been leading us to the personalized/precision medicine era.

Clinical Genome Sequencing Book

Clinical Genome Sequencing


  • Author : Aad Tibben
  • Publisher : Academic Press
  • Release Date : 2019-03-30
  • Genre: Medical
  • Pages : 258
  • ISBN 10 : 9780128133361

DOWNLOAD BOOK
Clinical Genome Sequencing Excerpt :

Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine. Features contributions from leading international researchers and practitioners versed in the psychosocial dimensions of genomic medicine implementation Presents clinical case studies that support concept illustration, making this an invaluable reference for students, researchers, and clinicians looking for practical guidance in this important and multifaceted topic area Details the current state of genomic testing, expectations of genome sequencing, patient consent, patient responses to sequencing data, uncertainties in genome sequencing, direct-to-consumer genome sequencing, and more

The Genetic Lottery Book
Score: 3.5
From 4 Ratings

The Genetic Lottery


  • Author : Kathryn Paige Harden
  • Publisher : Princeton University Press
  • Release Date : 2021-09-21
  • Genre: Science
  • Pages : 320
  • ISBN 10 : 9780691226705

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The Genetic Lottery Excerpt :

A provocative and timely case for how the science of genetics can help create a more just and equal society In recent years, scientists like Kathryn Paige Harden have shown that DNA makes us different, in our personalities and in our health—and in ways that matter for educational and economic success in our current society. In The Genetic Lottery, Harden introduces readers to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society. Reclaiming genetic science from the legacy of eugenics, this groundbreaking book offers a bold new vision of society where everyone thrives, regardless of how one fares in the genetic lottery.

American Jewish Year Book 2012 Book

American Jewish Year Book 2012


  • Author : Arnold Dashefsky
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-09
  • Genre: Social Science
  • Pages : 606
  • ISBN 10 : 9789400752047

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American Jewish Year Book 2012 Excerpt :

The 2012 American Jewish Year Book, “The Annual Record of American Jewish Civilization,” contains major chapters on Jewish secularism (Barry Kosmin and Ariela Keysar), Canadian Jewry (Morton Weinfeld, David Koffman, and Randal Schnoor), national affairs (Ethan Felson), Jewish communal affairs (Lawrence Grossman), Jewish population in the United States (Ira Sheskin and Arnold Dashefsky), and World Jewish population (Sergio DellaPergola). These chapters provide insight into major trends in the North American and world Jewish community. The volume also acts as a resource for the American Jewish community and for academics studying that community by supplying obituaries and lists of Jewish Federations, Jewish Community Centers, national Jewish organizations, Jewish overnight camps, Jewish museums, Holocaust museums, local and national Jewish periodicals, Jewish honorees, major recent events in the American Jewish community, and academic journals, articles, websites, and books. The volume should prove useful to social scientists and historians of the American Jewish community, Jewish communal workers, the press, and others interested in American and Canadian Jews.​

Who We are and how We Got Here Book
Score: 3.5
From 7 Ratings

Who We are and how We Got Here


  • Author : David Reich (Of Harvard Medical School)
  • Publisher : Oxford University Press
  • Release Date : 2018
  • Genre: DNA
  • Pages : 368
  • ISBN 10 : 9780198821250

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Who We are and how We Got Here Excerpt :

David Reich describes how the revolution in the ability to sequence ancient DNA has changed our understanding of the deep human past. This book tells the emerging story of our often surprising ancestry - the extraordinary ancient migrations and mixtures of populations that have made us who we are.

How to Practice Academic Medicine and Publish from Developing Countries  Book

How to Practice Academic Medicine and Publish from Developing Countries


  • Author : Samiran Nundy
  • Publisher : Springer Nature
  • Release Date : 2021-10-23
  • Genre: Medical
  • Pages : 465
  • ISBN 10 : 9789811652486

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How to Practice Academic Medicine and Publish from Developing Countries Excerpt :

This is an open access book. The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It addresses budding but struggling academics in low and middle-income countries. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials. It also serves as a guide towards establishing a research question and research methodology. It covers important concepts such as writing a paper, the submission process, dealing with rejection and revisions, and covers additional topics such as planning lectures and presentations. The book will be useful for graduates, postgraduates, teachers as well as physicians and practitioners all over the developing world who are interested in academic medicine and wish to do medical research.