Handbook of Isoelectric Focusing and Proteomics Book

Handbook of Isoelectric Focusing and Proteomics


  • Author : David Garfin
  • Publisher : Elsevier
  • Release Date : 2005-09-29
  • Genre: Science
  • Pages : 380
  • ISBN 10 : 9780080533629

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Handbook of Isoelectric Focusing and Proteomics Excerpt :

Isoelectric focusing (IEF) is a high-resolution, stand-alone technique that can be used as an analytical method or tool for protein purification. The only current book on the market, the Handbook of Isoelectric Focusing and Proteomics is the ideal 'one-stop' source for germane information in this discipline. This highly practical book also contains chapters on alternative methods that may pave the way in the search for efficient techniques for fractionating and purifying proteins. Complete with the history of IEF focusing to authors' insights and practical tips, this book is a must for anyone working in proteomics. * Is the only current book available on the subject * Includes author insights and practical tips * Is an ideal single source for students and researchers working in proteomics

Separation Techniques Applied to Omics Sciences Book

Separation Techniques Applied to Omics Sciences


  • Author : Ana Valéria Colnaghi Simionato
  • Publisher : Springer Nature
  • Release Date : 2021-10-09
  • Genre: Science
  • Pages : 273
  • ISBN 10 : 9783030772529

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Separation Techniques Applied to Omics Sciences Excerpt :

This book covers liquid chromatography, gas chromatography and capillary electrophoresis, the three main separation techniques lately available, applied to key omic sciences, such as genomics, proteomics, metabolomics and foodomics. The fundamentals of each technique are not covered herein. Instead, the recent advances in such techniques are presented focusing on the application to omics analyses and unique aspects in each case. This volume intends to offer wide ranging options available to researchers on omics sciences, and how to integrate them in order to achieve the comprehension of a biological system as a whole. Omic sciences have been of ultimate importance to comprehend the complex biochemical reactions and related events that occurs upon a biological system. The classical central dogma of molecular biology, which states that genetic information flows unidirectionally from DNA to RNA and then to proteins, has been gradually replaced by the systems biology approach. This book presents a multidisciplinary approach that explains the biological system as a whole, where the entire organism is influenced by a variety of internal events as well as by the environment, showing that each level of the biological information flux may influence the previous or the subsequent one.

Monolithic Silicas in Separation Science Book

Monolithic Silicas in Separation Science


  • Author : Klaus K. Unger
  • Publisher : John Wiley & Sons
  • Release Date : 2010-11-29
  • Genre: Science
  • Pages : 362
  • ISBN 10 : 9783527633265

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Monolithic Silicas in Separation Science Excerpt :

Edited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must-have information hitherto only scattered among journals. Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists.

Clinical Proteomics Book

Clinical Proteomics


  • Author : Jennifer E. Van Eyk
  • Publisher : John Wiley & Sons
  • Release Date : 2008-09-08
  • Genre: Science
  • Pages : 694
  • ISBN 10 : 9783527622160

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Clinical Proteomics Excerpt :

Unparalleled in its scope and depth, this book brings together proteomic approaches in diagnosis and treatment from all clinical fields, including clinical toxicology. The result is a new discipline in molecular medicine that will revolutionize the treatment and prevention of cancer, stroke and other severe diseases. Following an overview of clinical proteomics, the authors look at the technologies available, before moving on to cancer, cardiopulmonary disease, diabetes and stroke. A whole section is devoted to toxicity and the work is rounded off with a discussion of the future of clinical proteomics.

Genome and Proteome in Oncology Book

Genome and Proteome in Oncology


  • Author : Fotini Tzortzatou Stathopoulou
  • Publisher : Nova Publishers
  • Release Date : 2005
  • Genre: Medical
  • Pages : 384
  • ISBN 10 : 1594542856

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Genome and Proteome in Oncology Excerpt :

The nature of cancer disease, its probable causes, and the molecular and cellular mechanisms through which malignant tumours develop, have only recently begun to be understood in any appreciable detail. Cancer is fundamentally a disease of the genome, arising from dynamic changes occurring within DNA during the lifetime of the cell e.g. deletions, amplifications, point mutations, translocations, that can occur in any cell and that may interact in a variety of cellular pathways. The imbalance in the interplay between genetic and environmental factors can initiate malignancy. The determination of the human genome sequence is acclaimed as one of the great achievements made possible by the rapid progress in the available molecular biology tools achieved during the last few years. The sequence of the human genome promises to unveil invaluable information useful for the development of novel approaches in the diagnosis and treatment of cancer disease. This book includes part of the work of international experts on the most up-to-date developments of various aspects of research on genome and proteome in oncology. The scientists suggest that the genetic key to human complexity lies not in the number of genes but in how gene parts are used to build different products in a process of the mRNA transcript called alternative splicing.

Introducing Proteomics Book

Introducing Proteomics


  • Author : Josip Lovric
  • Publisher : John Wiley & Sons
  • Release Date : 2011-06-17
  • Genre: Science
  • Pages : 296
  • ISBN 10 : 9781119957195

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Introducing Proteomics Excerpt :

Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences. This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study. The text covers the following: Separation Technologies Analysis of Peptides/Proteins by Mass Spectrometry Strategies in Proteomics This contemporary text also includes numerous examples and explanations for why particular strategies are better than others for certain applications. In addition, Introducing Proteomics includes extensive references and a list of relevant proteomics information sources; essential for any student. This no-nonsense approach to the subject tells students exactly what they need to know, leaving out unnecessary information. The student companion site enhances learning and provides answers to the end of chapter problems. "I think this book will be a popular and valuable resource for students and newcomers to the field who would like to have an overview and initial understanding of what proteomics is about. The contents are well organized and address the major issues." —Professor Walter Kolch, Director, Systems Biology Ireland & Conway Institute, University College Dublin Companion Website www.wiley.com/go/lovric

The Evolution from Protein Chemistry to Proteomics Book

The Evolution from Protein Chemistry to Proteomics


  • Author : Roger L. Lundblad
  • Publisher : CRC Press
  • Release Date : 2005-10-14
  • Genre: Medical
  • Pages : 312
  • ISBN 10 : 9781420036404

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The Evolution from Protein Chemistry to Proteomics Excerpt :

Largely driven by major improvements in the analytical capability of mass spectrometry, proteomics is being applied to broader areas of experimental biology, ranging from oncology research to plant biology to environmental health. However, while it has already eclipsed solution protein chemistry as a discipline, it is still essentially an extension

Introducing Proteomics Book

Introducing Proteomics


  • Author : Josip Lovric
  • Publisher : John Wiley & Sons
  • Release Date : 2011-02-14
  • Genre: Science
  • Pages : 310
  • ISBN 10 : 9780470035245

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Introducing Proteomics Excerpt :

Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences. This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study. The text covers the following: Separation Technologies Analysis of Peptides/Proteins by Mass Spectrometry Strategies in Proteomics This contemporary text also includes numerous examples and explanations for why particular strategies are better than others for certain applications. In addition, Introducing Proteomics includes extensive references and a list of relevant proteomics information sources; essential for any student. This no-nonsense approach to the subject tells students exactly what they need to know, leaving out unnecessary information. The student companion site enhances learning and provides answers to the end of chapter problems. "I think this book will be a popular and valuable resource for students and newcomers to the field who would like to have an overview and initial understanding of what proteomics is about. The contents are well organized and address the major issues." —Professor Walter Kolch, Director, Systems Biology Ireland & Conway Institute, University College Dublin Companion Website www.wiley.com/go/lovric

Proteomics in Food Science Book

Proteomics in Food Science


  • Author : Michelle Lisa Colgrave
  • Publisher : Academic Press
  • Release Date : 2017-04-03
  • Genre: Technology & Engineering
  • Pages : 538
  • ISBN 10 : 9780128040577

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Proteomics in Food Science Excerpt :

Proteomics in Food Science: From Farm to Fork is a solid reference providing concepts and practical applications of proteomics for those in various disciplines of food science. The book covers a range of methods for elucidating the identity or composition of specific proteins in foods or cells related to food science, from spoilage organisms, to edible components. A variety of analytical platforms are described, ranging from the usage of simple electrophoresis, to more sophisticated mass spectrometry and bio-informatic platforms. The book is designed for food scientists, technologists, food industry workers, microbiologists, and public health workers, and can also be a valuable reference book for students. Includes a variety of analytical platforms, ranging from simple electrophoresis to more sophisticated mass spectrometry and bio-informatic platforms Presents analytical techniques for each food domain, including beverages, meats, dairy and eggs, fruit, fish/seafood, cereals, nuts, and grains that range from sample collection, proportion, and storage analysis Provides applications of proteomics in hot topics area of food safety, including food spoilage, pathogenic organisms, and allergens Covers major pathogens of concern e.g., Salmonella and applications to animal husbandry

Separation Methods In Proteomics Book

Separation Methods In Proteomics


  • Author : Gary B. Smejkal
  • Publisher : CRC Press
  • Release Date : 2005-12-12
  • Genre: Science
  • Pages : 536
  • ISBN 10 : 0824726995

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Separation Methods In Proteomics Excerpt :

Driven by the widespread growth of proteomic practices, protein separation techniques have been refined to minimize variability, optimize particular applications, and adapt to user preferences in the analysis of proteins. Separation Methods in Proteomics provides a comprehensive examination of all major separation techniques for proteomics research. Written as a compilation of hands-on methods exemplified by the work of several recognized leaders in the field, this book may serve as a guide for selection of the optimal separation strategies to solve particular biological problems. Recent progress in the development of robust analytical techniques and instrumentation has created the need for good quality biological samples that are subject to analysis. Emphasizing the importance of sample preparation, the book explains how proteomes can be divided into smaller, less complicated “subproteomes" for individual analysis. It also highlights several hybrid approaches that take into account protein interactions. Including applications of the separation methods currently employed in proteomic analyses for both clinical and basic research, Separation Methods in Proteomics contains practical information that can enhance the current and future endeavors of scientists in proteomics, genomics, transcriptomics, biomarker discovery, and drug discovery.

Genomics  Proteomics and Vaccines Book

Genomics Proteomics and Vaccines


  • Author : Guido Grandi
  • Publisher : John Wiley & Sons
  • Release Date : 2004-08-13
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780470093924

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Genomics Proteomics and Vaccines Excerpt :

While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly. Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens. This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions

Issues in Chemical  Biological  and Medical Engineering  2013 Edition Book

Issues in Chemical Biological and Medical Engineering 2013 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-05-01
  • Genre: Technology & Engineering
  • Pages : 660
  • ISBN 10 : 9781490108926

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Issues in Chemical Biological and Medical Engineering 2013 Edition Excerpt :

Issues in Chemical, Biological, and Medical Engineering: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Biosystems Engineering. The editors have built Issues in Chemical, Biological, and Medical Engineering: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Biosystems Engineering in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Chemical, Biological, and Medical Engineering: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Neuroproteomics Book

Neuroproteomics


  • Author : Oscar Alzate
  • Publisher : CRC Press
  • Release Date : 2009-10-26
  • Genre: Science
  • Pages : 354
  • ISBN 10 : 1420076264

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Neuroproteomics Excerpt :

In this, the post-genomic age, our knowledge of biological systems continues to expand and progress. As the research becomes more focused, so too does the data. Genomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we begin to unravel the complex mysteries of neurological diseases that less than a generation ago seemed opaque to our inquiries, if not altogether intractable. Edited by Dr. Oscar Alzate, Neuroproteomics is the newest volume in the CRC Press Frontiers of Neuroscience Series. With an extensive background in mathematics and physics, Dr. Alzate exemplifies the newest generation of biological systems researchers. He organizes research and data contributed from all across the world to present an overview of neuroproteomics that is practical and progressive. Bolstered by each new discovery, researchers employing multiple methods of inquiry gain a deeper understanding of the key biological problems related to brain function, brain structure, and the complexity of the nervous system. This in turn is leading to new understanding about diseases of neurological deficit such as Parkinson’s and Alzheimer’s. Approaches discussed in the book include mass spectrometry, electrophoresis, chromatography, surface plasmon resonance, protein arrays, immunoblotting, computational proteomics, and molecular imaging. Writing about their own work, leading researchers detail the principles, approaches, and difficulties of the various techniques, demonstrating the questions that neuroproteomics can answer and those it raises. New challenges wait, not the least of which is the identification of potential methods to regulate the structures and functions of key protein interaction networks. Ultimately, those building on the foundation presented here will advance our understanding of the brain and show us ways to abate the suffering caused by neurological

Two Dimensional Liquid Chromatography Book

Two Dimensional Liquid Chromatography


  • Author : Oliver Jones
  • Publisher : Springer Nature
  • Release Date : 2020-07-13
  • Genre: Science
  • Pages : 75
  • ISBN 10 : 9789811561900

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Two Dimensional Liquid Chromatography Excerpt :

This book addresses the growing interest in the field of two-dimensional liquid chromatography (2DLC), a powerful approach to increasing resolution, available peak capacity, and selectivity in analytical chromatography. 2DLC is suitable for many applications, including in the pharmaceutical and polymer industries and the omic sciences (metabolomics, lipidomics and proteomics). Thanks to recent advances in technology and software the instrumentation needed to perform 2D-LC is broadly available to the analytical community in both industry and academia. Indeed, the technique can now be considered ready for application in R&D as well as in QA and QC labs, yet it is not widely known about outside academic laboratories and is rarely taught at the undergraduate level. This book outlines the main principles and features of 2D-LC (including comprehensive and heart-cutting modes, method development and real world applications) to enable modern analysts to start using this fascinating technique. The book offers an ideal starting point for those wishing to get into 2D-LC and will also be of interest to more experienced scientists in the field.

Proteome Characterization and Proteomics Book

Proteome Characterization and Proteomics


  • Author : Timothy D. Veenstra
  • Publisher : Academic Press
  • Release Date : 2003-10-01
  • Genre: Science
  • Pages : 413
  • ISBN 10 : 9780080569154

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Proteome Characterization and Proteomics Excerpt :

The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. Discusses proteomics in the postgenomic age Includes various strategies for quantitative proteomics Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics