Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics Book

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics


  • Author : Susanta K. Sarkar
  • Publisher : Unknown
  • Release Date : 2016
  • Genre: SCIENCE
  • Pages : null
  • ISBN 10 : 1681742446

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Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics Excerpt :

This is an overview of single molecule physics, the study of both equilibrium and non-equilibrium properties at the single molecule level. It begins with an introduction to this fascinating science and includes a chapter on how to build the most popular instrument for single molecule biophysics, the total internal reflection fluorescence (TIRF) microscope. It concludes with the Poisson process approach to statistical mechanics, explaining how to relate the process to diverse areas and see how data analysis and error bars are integral parts of science.

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics Book

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics


  • Author : Susanta K Sarkar
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2016-04-01
  • Genre: Science
  • Pages : 74
  • ISBN 10 : 9781681741161

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Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics Excerpt :

This is an overview of single molecule physics, the study of both equilibrium and non-equilibrium properties at the single molecule level. It begins with an introduction to this fascinating science and includes a chapter on how to build the most popular instrument for single molecule biophysics, the total internal reflection fluorescence (TIRF) microscope. It concludes with the Poisson process approach to statistical mechanics, explaining how to relate the process to diverse areas and see how data analysis and error bars are integral parts of science.

Computational Biochemistry and Biophysics Book

Computational Biochemistry and Biophysics


  • Author : Oren M. Becker
  • Publisher : CRC Press
  • Release Date : 2001-02-09
  • Genre: Science
  • Pages : 512
  • ISBN 10 : 9780824741402

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Computational Biochemistry and Biophysics Excerpt :

Covering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret biomolecular properties gleaned from computer-generated membrane simulations. It also demonstrates comparative protein structure modeling, outlines computer-aided drug design, discusses Bayesian statistics in molecular and structural biology, and examines the RISM-SCF/MCSCF approach to chemical processes in solution.

Molecular and Cellular Biophysics Book
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Molecular and Cellular Biophysics


  • Author : Meyer B. Jackson
  • Publisher : Cambridge University Press
  • Release Date : 2006-01-12
  • Genre: Science
  • Pages : null
  • ISBN 10 : 1139447246

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Molecular and Cellular Biophysics Excerpt :

Molecular and Cellular Biophysics provides advanced undergraduate and graduate students with a foundation in the basic concepts of biophysics. Students who have taken physical chemistry and calculus courses will find this book an accessible and valuable aid in learning how these concepts can be used in biological research. The text provides a rigorous treatment of the fundamental theories in biophysics and illustrates their application with examples. Conformational transitions of proteins are studied first using thermodynamics, and subsequently with kinetics. Allosteric theory is developed as the synthesis of conformational transitions and association reactions. Basic ideas of thermodynamics and kinetics are applied to topics such as protein folding, enzyme catalysis and ion channel permeation. These concepts are then used as the building blocks in a treatment of membrane excitability. Through these examples, students will gain an understanding of the general importance and broad applicability of biophysical principles to biological problems.

Biophysics Book

Biophysics


  • Author : William Bialek
  • Publisher : Princeton University Press
  • Release Date : 2012-12-17
  • Genre: Science
  • Pages : 640
  • ISBN 10 : 9781400845576

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Biophysics Excerpt :

Interactions between the fields of physics and biology reach back over a century, and some of the most significant developments in biology--from the discovery of DNA's structure to imaging of the human brain--have involved collaboration across this disciplinary boundary. For a new generation of physicists, the phenomena of life pose exciting challenges to physics itself, and biophysics has emerged as an important subfield of this discipline. Here, William Bialek provides the first graduate-level introduction to biophysics aimed at physics students. Bialek begins by exploring how photon counting in vision offers important lessons about the opportunities for quantitative, physics-style experiments on diverse biological phenomena. He draws from these lessons three general physical principles--the importance of noise, the need to understand the extraordinary performance of living systems without appealing to finely tuned parameters, and the critical role of the representation and flow of information in the business of life. Bialek then applies these principles to a broad range of phenomena, including the control of gene expression, perception and memory, protein folding, the mechanics of the inner ear, the dynamics of biochemical reactions, and pattern formation in developing embryos. Featuring numerous problems and exercises throughout, Biophysics emphasizes the unifying power of abstract physical principles to motivate new and novel experiments on biological systems. Covers a range of biological phenomena from the physicist's perspective Features 200 problems Draws on statistical mechanics, quantum mechanics, and related mathematical concepts Includes an annotated bibliography and detailed appendixes Instructor's manual (available only to teachers)

Equilibria and Kinetics of Biological Macromolecules Book

Equilibria and Kinetics of Biological Macromolecules


  • Author : Prof. Jan Hermans
  • Publisher : John Wiley & Sons
  • Release Date : 2013-10-22
  • Genre: Science
  • Pages : 524
  • ISBN 10 : 9781118733776

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Equilibria and Kinetics of Biological Macromolecules Excerpt :

Progressively builds a deep understanding of macromolecular behavior Based on each of the authors' roughly forty years of biophysics research and teaching experience, this text instills readers with a deep understanding of the biophysics of macromolecules. It sets a solid foundation in the basics by beginning with core physical concepts such as thermodynamics, quantum chemical models, molecular structure and interactions, and water and the hydrophobic effect. Next, the book examines statistical mechanics, protein-ligand binding, and conformational stability. Finally, the authors address kinetics and equilibria, exploring underlying theory, protein folding, and stochastic models. With its strong emphasis on molecular interactions, Equilibria and Kinetics of Biological Macromolecules offers new insights and perspectives on proteins and other macromolecules. The text features coverage of: Basic theory, applications, and new research findings Related topics in thermodynamics, quantum mechanics, statistical mechanics, and molecular simulations Principles and applications of molecular simulations in a dedicated chapter and interspersed throughout the text Macromolecular binding equilibria from the perspective of statistical mechanics Stochastic processes related to macromolecules Suggested readings at the end of each chapter include original research papers, reviews and monographs, enabling readers to explore individual topics in greater depth. At the end of the text, ten appendices offer refreshers on mathematical treatments, including probability, computational methods, Poisson equations, and defining molecular boundaries. With its classroom-tested pedagogical approach, Equilibria and Kinetics of Biological Macromolecules is recommended as a graduate-level textbook for biophysics courses and as a reference for researchers who want to strengthen their understanding of macromolecular behavior.

Electrostatic Effects in Soft Matter and Biophysics Book

Electrostatic Effects in Soft Matter and Biophysics


  • Author : Christian Holm
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 510
  • ISBN 10 : 9789401005777

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Electrostatic Effects in Soft Matter and Biophysics Excerpt :

Soft Condensed Matter commonly deals with materials that are mechanically soft and, more importantly, particularly prone to thermal fluctuation effects. Charged soft matter systems are especially interesting: they can be manufactured artificially as polyelectrolytes to serve as superabsorbers in dypers, as flocculation and retention agents, as thickeners and gelling agents, and as oil-recovery process aids. They are also abundant in living organisms, mostly performing important structural (e.g. membranes) and functional (e.g. DNA) tasks. The book describes the many areas in soft matter and biophysics where electrostatic interactions play an important role. It offers in-depth coverage of recent theoretical approaches, advances in computer simulation, and novel experimental techniques. Readership: Advanced undergraduate level in physics, physical chemistry, and theoretical biochemistry.

The Physical Basis of Biochemistry Book

The Physical Basis of Biochemistry


  • Author : Peter R. Bergethon
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-14
  • Genre: Science
  • Pages : 567
  • ISBN 10 : 9781475729634

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The Physical Basis of Biochemistry Excerpt :

The objective of this book is to provide a unifying approach to the study of biophysical chemistry for the advanced undergraduate who has had a year of physics, organic chem istry, calculus, and biology. This book began as a revised edition of Biophysical Chemistry: Molecules to Membranes, which Elizabeth Simons and I coauthored. That short volume was written in an attempt to provide a concise text for a one-semester course in biophysical chemistry at the graduate level. The experience of teaching biophysical chemistry to bi ologically oriented students over the last decade has made it clear that the subject requires a more fundamental text that unifies the many threads of modem science: physics, chem istry, biology, mathematics, and statistics. This book represents that effort. This volume is not a treatment of modem biophysical chemistry with its rich history and many contro versies, although a book on that topic is also needed. The Physical Basis of Biochemistry is an introduction to the philosophy and practice of an interdisciplinary field in which biological systems are explored using the quantitative perspective of the physical scientist. I have three primary objectives in this volume: one, to provide a unifying picture of the interdisciplinary threads from which the tapestry of biophysical studies is woven; two, to provide an insight into the power of the modeling approach to scientific investigation; and three, to communicate a sense of excitement for the activity and wholesome argument that characterize this field of study.

Entropy and Free Energy in Structural Biology Book

Entropy and Free Energy in Structural Biology


  • Author : Hagai Meirovitch
  • Publisher : CRC Press
  • Release Date : 2020-08-14
  • Genre: Computers
  • Pages : 374
  • ISBN 10 : 9781000072327

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Entropy and Free Energy in Structural Biology Excerpt :

Nuclear Structure Physics connects to some of our fundamental questions about the creation of the universe and its basic constituents. At the same time, precise knowledge on the subject has led to the development of many important tools for humankind such as proton therapy and radioactive dating, among others. This book has chapters on some of the crucial and trending research topics in nuclear structure, including the nuclei lying on the extremes of spin, isospin and mass. A better theoretical understanding of these topics is important beyond the confines of the nuclear structure community. Additionally, the book will showcase the applicability and success of the different nuclear effective interaction parameters near the drip line, where hints for level reordering have already been seen, and where one can test the isospin-dependence of the interaction. The book offers comprehensive coverage of the most essential topics, including: • Nuclear Structure of Nuclei at or Near Drip-Lines • Synthesis challenges and properties of Superheavy nuclei • Nuclear Structure and Nuclear models - Ab-initio calculations, cluster models, Shell-model/DSM, RMF, Skyrme • Shell Closure, Magicity and other novel features of nuclei at extremes • Structure of Toroidal, Bubble Nuclei, halo and other exotic nuclei These topics are not only very interesting from a theoretical nuclear physics perspective but are also quite complimentary for ongoing nuclear physics experimental programs worldwide. The book chapters, written by experienced and well-known researchers/experts, will be helpful for master students, graduate students and researchers and serve as a standard and up-to-date research reference book on the topics covered.

Molecular Dynamics Simulations in Statistical Physics  Theory and Applications Book

Molecular Dynamics Simulations in Statistical Physics Theory and Applications


  • Author : Hiqmet Kamberaj
  • Publisher : Springer Nature
  • Release Date : 2020-03-20
  • Genre: Science
  • Pages : 463
  • ISBN 10 : 9783030357023

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Molecular Dynamics Simulations in Statistical Physics Theory and Applications Excerpt :

This book presents computer simulations using molecular dynamics techniques in statistical physics, with a focus on macromolecular systems. The numerical methods are introduced in the form of computer algorithms and can be implemented in computers using any desired computer programming language, such as Fortran 90, C/C++, and others. The book also explains how some of these numerical methods and their algorithms can be implemented in the existing computer programming software of macromolecular systems, such as the CHARMM program. In addition, it examines a number of advanced concepts of computer simulation techniques used in statistical physics as well as biological and physical systems. Discussing the molecular dynamics approach in detail to enhance readers understanding of the use of this method in statistical physics problems, it also describes the equations of motion in various statistical ensembles to mimic real-world experimental conditions. Intended for graduate students and research scientists working in the field of theoretical and computational biophysics, physics and chemistry, the book can also be used by postgraduate students of other disciplines, such as applied mathematics, computer sciences, and bioinformatics. Further, offering insights into fundamental theory, it as a valuable resource for expert practitioners and programmers and those new to the field.

Explicit Symmetry Breaking in Electrodynamic Systems and Electromagnetic Radiation Book

Explicit Symmetry Breaking in Electrodynamic Systems and Electromagnetic Radiation


  • Author : Dhiraj Sinha
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2016-04-01
  • Genre: Science
  • Pages : 93
  • ISBN 10 : 9781681743585

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Explicit Symmetry Breaking in Electrodynamic Systems and Electromagnetic Radiation Excerpt :

This book is an introduction to the concept of symmetries in electromagnetism and explicit symmetry breaking. It begins with a brief background on the origin of the concept of symmetry and its meaning in fields such as architecture, mathematics and physics. Despite the extensive developments of symmetry in these fields, it has yet to be applied to the context of classical electromagnetism and related engineering applications. This book unravels the beauty and excitement of this area to scientists and engineers.

Physics Briefs Book

Physics Briefs


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1994
  • Genre: Physics
  • Pages : null
  • ISBN 10 : UOM:39015027829855

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Physics Briefs Excerpt :

Women and Physics Book

Women and Physics


  • Author : Laura McCullough
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2016-04-01
  • Genre: Science
  • Pages : 59
  • ISBN 10 : 9781681742786

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Women and Physics Excerpt :

This book begins with an examination of the numbers of women in physics in English-speaking countries, moving on to examine factors that affect girls and their decision to continue in science, right through to education and on into the problems that women in physics careers face. Looking at all of these topics with one eye on the progress that the field has made in the past few years, and another on those things that we have yet to address, the book surveys the most current research as it tries to identify strategies and topics that have significant impact on issues that women have in the field.

Single Molecule Spectroscopy Book

Single Molecule Spectroscopy


  • Author : R. Rigler
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 355
  • ISBN 10 : 9783642565441

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Single Molecule Spectroscopy Excerpt :

The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.