Single Molecule Spectroscopy in Chemistry  Physics and Biology Book

Single Molecule Spectroscopy in Chemistry Physics and Biology


  • Author : Astrid Graslund
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-04-17
  • Genre: Molecular spectroscopy
  • Pages : 596
  • ISBN 10 : 9783642025983

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Single Molecule Spectroscopy in Chemistry Physics and Biology Excerpt :

Written by the leading experts in the field, this book describes the development and current state of the art in single molecule spectroscopy. The application of this technique, which started 1989, in physics, chemistry and biosciences is displayed.

Single Molecule Spectroscopy Book

Single Molecule Spectroscopy


  • Author : R. Rigler
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 355
  • ISBN 10 : 9783642565441

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Single Molecule Spectroscopy Excerpt :

The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.

Fluorescence Fluctuation Spectroscopy  FFS  Book

Fluorescence Fluctuation Spectroscopy FFS


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2012-12-28
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780123884237

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Fluorescence Fluctuation Spectroscopy FFS Excerpt :

This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume covers Fluorescence Fluctuation Spectroscopy Contains chapters on such topics as Time-integrated fluorescence cumulant analysis, Pulsed Interleaved Excitation, and raster image correlation spectroscopy and number and brightness analysis. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers fluorescence fluctuation spectroscopy Contains chapters on such topics as time-integrated fluorescence cumulant analysis, pulsed interleaved excitation, and raster image correlation spectroscopy and number and brightness analysis.

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics Book

Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics


  • Author : Susanta K Sarkar
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2016-04-01
  • Genre: Science
  • Pages : 74
  • ISBN 10 : 9781681741802

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Single Molecule Biophysics and Poisson Process Approach to Statistical Mechanics Excerpt :

This is an overview of single molecule physics, the study of both equilibrium and non-equilibrium properties at the single molecule level. It begins with an introduction to this fascinating science and includes a chapter on how to build the most popular instrument for single molecule biophysics, the total internal reflection fluorescence (TIRF) microscope. It concludes with the Poisson process approach to statistical mechanics, explaining how to relate the process to diverse areas and see how data analysis and error bars are integral parts of science.

Single Molecule Science Book

Single Molecule Science


  • Author : Krishnarao Appasani
  • Publisher : Cambridge University Press
  • Release Date : 2022-05-31
  • Genre: Medical
  • Pages : 550
  • ISBN 10 : 9781108423366

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Single Molecule Science Excerpt :

A comprehensive volume that brings together authoritative overviews of single molecule science techniques from a biological perspective.

High Speed Atomic Force Microscopy in Biology Book

High Speed Atomic Force Microscopy in Biology


  • Author : Toshio Ando
  • Publisher : Springer Nature
  • Release Date : 2022-03-23
  • Genre: Science
  • Pages : 319
  • ISBN 10 : 9783662647851

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High Speed Atomic Force Microscopy in Biology Excerpt :

This first book on high-speed atomic force microscopy (HS-AFM) is intended for students and biologists who want to use HS-AFM in their research. It provides straightforward explanations of the principle and techniques of AFM and HS-AFM. Numerous examples of HS-AFM studies on proteins demonstrate how to apply this new form of microscopy to specific biological problems. Several precautions for successful imaging and the preparation of cantilever tips and substrate surfaces will greatly benefit first-time users of HS-AFM. In turn, the instrumentation techniques detailed in Chapter 4 can be skipped, but will be useful for engineers and scientists who want to develop the next generation of high-speed scanning probe microscopes for biology. The book is intended to facilitate the first-time use of this new technique, and to inspire students and researchers to tackle their own specific biological problems by directly observing dynamic events occurring in the nanoscopic world. Microscopy in biology has recently entered a new era with the advent of high-speed atomic force microscopy (HS-AFM). Unlike optical microscopy, electron microscopy, and conventional slow AFM, it allows us to directly observe biological molecules in physiological environments. Molecular “movies” created using HS-AFM can directly reveal how molecules behave and operate, without the need for subsequent complex analyses and roundabout interpretations. It also allows us to directly monitor morphological change in live cells, and dynamic molecular events occurring on the surfaces of living bacteria and intracellular organelles. As HS-AFM instruments were recently commercialized, in the near future HS-AFM is expected to become a common tool in biology, and will enhance and accelerate our understanding of biological phenomena.

Handbook of Single Molecule Fluorescence Spectroscopy Book

Handbook of Single Molecule Fluorescence Spectroscopy


  • Author : Chris Gell
  • Publisher : Oxford University Press on Demand
  • Release Date : 2006-08-17
  • Genre: Science
  • Pages : 262
  • ISBN 10 : 9780198529422

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Handbook of Single Molecule Fluorescence Spectroscopy Excerpt :

This is a practical introduction to single molecule fluorescence experiments, the analysis of the data, and applications of the techniques to the study of biological structure and function.

Practical Aspects of Computational Chemistry I Book

Practical Aspects of Computational Chemistry I


  • Author : Jerzy Leszczynski
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-13
  • Genre: Science
  • Pages : 680
  • ISBN 10 : 9789400709188

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Practical Aspects of Computational Chemistry I Excerpt :

Practical Aspects of Computational Chemistry I: An Overview of the Last Two Decades and Current Trends gathers the advances made within the last 20 years by well-known experts in the area of theoretical and computational chemistry and physics. The title itself reflects the celebration of the twentieth anniversary of the “Conference on Current Trends in Computational Chemistry (CCTCC)” to which all authors have participated and contributed to its success. This volume poses (and answers) important questions of interest to the computational chemistry community and beyond. What is the historical background of the “Structural Chemistry”? Is there any way to avoid the problem of intruder state in the multi-reference formulation? What is the recent progress on multi-reference coupled cluster theory? Starting with a historical account of structural chemistry, the book focuses on the recent advances made in promising theories such as many body Brillouin-Wigner theory, multireference state-specific coupled cluster theory, relativistic effect in chemistry, linear and nonlinear optical properties of molecules, solution to Kohn-Sham problem, electronic structure of solid state materials, development of model core potential, quantum Monte Carlo method, nano and molecular electronics, dynamics of photodimerization and excited states, intermolecular interactions, hydrogen bonding and non-hydrogen bonding interactions, conformational flexibility, metal cations in zeolite catalyst and interaction of nucleic acid bases with minerals. Practical Aspects of Computational Chemistry I: An Overview of the Last Two Decades and Current Trends is aimed at theoretical and computational chemists, physical chemists, materials scientists, and particularly those who are eager to apply computational chemistry methods to problem of chemical and physical importance. This book will provide valuable information to undergraduate, graduate, and PhD students as well as to established researchers.

Proteins in Solution and at Interfaces Book

Proteins in Solution and at Interfaces


  • Author : Juan M. Ruso
  • Publisher : John Wiley & Sons
  • Release Date : 2013-01-31
  • Genre: Science
  • Pages : 500
  • ISBN 10 : 9781118523179

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Proteins in Solution and at Interfaces Excerpt :

Explores new applications emerging from our latestunderstanding of proteins in solution and at interfaces Proteins in solution and at interfaces increasingly serve as thestarting point for exciting new applications, from biomimeticmaterials to nanoparticle patterning. This book surveys the stateof the science in the field, offering investigators a currentunderstanding of the characteristics of proteins in solution and atinterfaces as well as the techniques used to study thesecharacteristics. Moreover, the authors explore many of the new andemerging applications that have resulted from the most recentstudies. Topics include protein and protein aggregate structure;computational and experimental techniques to study proteinstructure, aggregation, and adsorption; proteins in non-standardconditions; and applications in biotechnology. Proteins in Solution and at Interfaces is divided intotwo parts: Part One introduces concepts as well as theoretical andexperimental techniques that are used to study protein systems,including X-ray crystallography, nuclear magnetic resonance, smallangle scattering, and spectroscopic methods Part Two examines current and emerging applications,including nanomaterials, natural fibrous proteins, and biomolecularthermodynamics The book's twenty-three chapters have been contributed byleading experts in the field. These contributions are based on athorough review of the latest peer-reviewed findings as well as theauthors' own research experience. Chapters begin with a discussionof core concepts and then gradually build in complexity, concludingwith a forecast of future developments. Readers will not only gain a current understanding of proteinsin solution and at interfaces, but also will discover howtheoretical and technical developments in the field can betranslated into new applications in material design, geneticengineering, personalized medicine, drug delivery, biosensors, andbiotechnology.

Understanding Light Microscopy Book

Understanding Light Microscopy


  • Author : Jeremy Sanderson
  • Publisher : John Wiley & Sons
  • Release Date : 2019-03-04
  • Genre: Science
  • Pages : 848
  • ISBN 10 : 9781118696743

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Understanding Light Microscopy Excerpt :

Introduces readers to the enlightening world of the modern light microscope There have been rapid advances in science and technology over the last decade, and the light microscope, together with the information that it gives about the image, has changed too. Yet the fundamental principles of setting up and using a microscope rests upon unchanging physical principles that have been understood for years. This informative, practical, full-colour guide fills the gap between specialised edited texts on detailed research topics, and introductory books, which concentrate on an optical approach to the light microscope. It also provides comprehensive coverage of confocal microscopy, which has revolutionised light microscopy over the last few decades. Written to help the reader understand, set up, and use the often very expensive and complex modern research light microscope properly, Understanding Light Microscopy keeps mathematical formulae to a minimum—containing and explaining them within boxes in the text. Chapters provide in-depth coverage of basic microscope optics and design; ergonomics; illumination; diffraction and image formation; reflected-light, polarised-light, and fluorescence microscopy; deconvolution; TIRF microscopy; FRAP & FRET; super-resolution techniques; biological and materials specimen preparation; and more. Gives a didactic introduction to the light microscope Encourages readers to use advanced fluorescence and confocal microscopes within a research institute or core microscopy facility Features full-colour illustrations and workable practical protocols Understanding Light Microscopy is intended for any scientist who wishes to understand and use a modern light microscope. It is also ideal as supporting material for a formal taught course, or for individual students to learn the key aspects of light microscopy through their own study.

Advances in Quantum Theory Book

Advances in Quantum Theory


  • Author : Ion Cotaescu
  • Publisher : BoD – Books on Demand
  • Release Date : 2012-02-15
  • Genre: Science
  • Pages : 262
  • ISBN 10 : 9789535100874

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Advances in Quantum Theory Excerpt :

The quantum theory is the first theoretical approach that helps one to successfully understand the atomic and sub-atomic worlds which are too far from the cognition based on the common intuition or the experience of the daily-life. This is a very coherent theory in which a good system of hypotheses and appropriate mathematical methods allow one to describe exactly the dynamics of the quantum systems whose measurements are systematically affected by objective uncertainties. Thanks to the quantum theory we are able now to use and control new quantum devices and technologies in quantum optics and lasers, quantum electronics and quantum computing or in the modern field of nano-technologies.

Engineering  Medicine and Science at the Nano Scale Book

Engineering Medicine and Science at the Nano Scale


  • Author : Stephen J. Fonash
  • Publisher : John Wiley & Sons
  • Release Date : 2018-08-21
  • Genre: Technology & Engineering
  • Pages : 296
  • ISBN 10 : 9783527692910

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Engineering Medicine and Science at the Nano Scale Excerpt :

Students at universities the world over will benefit from the authors' concise treatment, arising out of lectures given for a graduate and advanced undergraduate course at Penn State University (USA) and University of Technology Delft (NL). The textbook begins by addressing, in general terms, the phenomena and peculiarities that occur at the nanoscale. In the following five chapters, readers are introduced in detail to nanoscale physics, chemistry, materials science, and biology, followed by chapters on synthesis and fabrication as well as characterization at the nanoscale. In the next four chapters a variety of exemplary applications taken from a wide range of sectors are also presented and discussed. Concerns for safety, environmental impact, workforce development, economic wellbeing, and societal change issues arising from nanotechnology are woven throughout the book and additionally form the focus of the last two chapters.

Unimolecular and Supramolecular Electronics II Book

Unimolecular and Supramolecular Electronics II


  • Author : Robert M. Metzger
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-10
  • Genre: Science
  • Pages : 272
  • ISBN 10 : 9783642273988

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Unimolecular and Supramolecular Electronics II Excerpt :

Molecular Electronic Junction Transport: Some Pathways and Some Ideas, by Gemma C. Solomon, Carmen Herrmann and Mark A. Ratner Unimolecular Electronic Devices, by Robert M. Metzger and Daniell L. Mattern Active and Non-Active Large-Area Metal–Molecules–Metal Junctions, by Barbara Branchi, Felice C. Simeone and Maria A. Rampi Charge Transport in Single Molecular Junctions at the Solid/Liquid Interface, by Chen Li, Artem Mishchenko and Thomas Wandlowski Tunneling Spectroscopy of Organic Monolayers and Single Molecules, by K. W. Hipps Single Molecule Logical Devices, by Nicolas Renaud, Mohamed Hliwa and Christian Joachim

Single Molecule Biophysics Book

Single Molecule Biophysics


  • Author : Tamiki Komatsuzaki
  • Publisher : Wiley
  • Release Date : 2011-11-16
  • Genre: Science
  • Pages : 512
  • ISBN 10 : 1118131398

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Single Molecule Biophysics Excerpt :

Discover the experimental and theoretical developments in optical single-molecule spectroscopy that are changing the ways we think about molecules and atoms The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This latest volume explores the advent of optical single-molecule spectroscopy, and how atomic force microscopy has empowered novel experiments on individual biomolecules, opening up new frontiers in molecular and cell biology and leading to new theoretical approaches and insights. Organized into two parts—one experimental, the other theoretical—this volume explores advances across the field of single-molecule biophysics, presenting new perspectives on the theoretical properties of atoms and molecules. Single-molecule experiments have provided fresh perspectives on questions such as how proteins fold to specific conformations from highly heterogeneous structures, how signal transductions take place on the molecular level, and how proteins behave in membranes and living cells.This volume is designed to further contribute to the rapid development of single-molecule biophysics research. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.

Methods for Studying Nucleic Acid Drug Interactions Book

Methods for Studying Nucleic Acid Drug Interactions


  • Author : Meni Wanunu
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Genre: Medical
  • Pages : 392
  • ISBN 10 : 9781439839744

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Methods for Studying Nucleic Acid Drug Interactions Excerpt :

Since most therapeutic efforts have been predominantly focused on pharmaceuticals that target proteins, there is an unmet need to develop drugs that intercept cellular pathways that critically involve nucleic acids. Progress in the discovery of nucleic acid binding drugs naturally relies on the availability of analytical methods that assess the efficacy and nature of interactions between nucleic acids and their putative ligands. This progress can benefit tremendously from new methods that probe nucleic acid/ligand interactions both rapidly and quantitatively. A variety of novel methods for these studies have emerged in recent years, and Methods for Studying DNA/Drug Interactions highlights new and non-conventional methods for exploring nucleic acid/ligand interactions. Designed to present drug-developing companies with a survey of possible future techniques, the book compares their drawbacks and advantages with respect to commonly used tools. Perhaps more importantly, this book was written to inspire young scientists to continue to advance these methods into fruition, especially in light of current capabilities for assay miniaturization and enhanced sensitivity using microfluidics and nanomaterials.