Sox2 Book


  • Author : Hisato Kondoh
  • Publisher : Academic Press
  • Release Date : 2015-08-24
  • Genre: Science
  • Pages : 344
  • ISBN 10 : 9780128004203

Sox2 Excerpt :

Sox2: Biology and Role in Development and Disease offers a thorough discussion of the important role of Sox2 in cellular and developmental processes, aimed at facilitating greater understanding of how Sox2 functions across different disciplines. The book discusses the basic biology of Sox2 to help establish the critical foundational knowledge necessary for deeper molecular and functional analysis. The book also provides insight into how the Sox2 transcription factor plays a key role in pluripotency induction, maintenance, and development. Helpful as a tool to organize new research projects, the book assists with preparing lessons, seminars, and thesis or research papers, thereby circumventing the need to spend hours searching through journal databases. A single source for the basic biology of Sox2, Sox2: Biology and Its Role in Development and Disease provides information on networks, gene regulation, and regulatory function in a number of cell types and tissues types. Discusses the important role of Sox2 in cellular and developmental processes Facilitates a greater understanding of how Sox2 functions across different disciplines Assists in identifying, circumventing and modifying the dynamics of Sox2 in cell types Provides greater understanding of the structure of Sox2 and its gene networks Identifies aspects of phenotypic spectrum uncovered following greater understanding of Sox2 during development

Handbook of Stem Cells Book

Handbook of Stem Cells

  • Author : Robert Lanza
  • Publisher : Gulf Professional Publishing
  • Release Date : 2004
  • Genre: Stem cells
  • Pages : 888
  • ISBN 10 : 0124366422

Handbook of Stem Cells Excerpt :

Accompanying CD-ROM (in v. 2) has image collections which can be saved in PowerPoint or HTML.

Stem Cells and Cancer Book

Stem Cells and Cancer

  • Author : Sadhan Majumder
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-06-07
  • Genre: Medical
  • Pages : 296
  • ISBN 10 : 0387896112

Stem Cells and Cancer Excerpt :

Cancer is a primary cause of human mortality worldwide. Despite decades of basic and clinical research, the outcome for most cancer patients is still dismal. Some stumbling blocks to developing effective therapy include the heterogeneity of cancer tissues, the lack of knowledge about the critical molecular mechanisms in cancer tissues (which are typically aberrant compared with mechanisms in normal tissue), and the lack of good mechanism-based therapeutic approaches. The recent findings that most cancers contain a small fraction of self-renewing, differentiation-blocked stem cell-like cells (cancer stem cells) and that it is these cells—and not the major bulk of the tissue—that are the root cause for cancer initiation and metastasis have also highlighted the need to change our approach to cancer therapy. The objectives of this book, therefore, would be to impart up-to-date information about the role of stem cells in the development of normal and cancerous tissue, the mechanisms that differentiate normal from cancerous functions, and the use of these findings in developing mechanism-based therapies.

Stem and Progenitor Cells in the Central Nervous System Book

Stem and Progenitor Cells in the Central Nervous System

  • Author : R.S. Nowakowski
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2004
  • Genre: Medical
  • Pages : 212
  • ISBN 10 : 9783805578707

Stem and Progenitor Cells in the Central Nervous System Excerpt :

This publication focuses on the biology of stem and progenitor cells in the developing and mature central nervous system, their response to trauma and potential uses in therapy. The authors, who are leading experts in the field, address topical questions from both basic and clinical neuroscience perspectives such as: non-invasive imaging of stem cell division; the origins of regional diversity in cell types and cell numbers in the stem cell progeny; factors that regulate generation of neurons and glial cells from stem cells during normal development; the role of genetic and environmental factors in the regulation of stem cell function; the role of stem cells in mediating the effects of brain trauma and its recovery, and the therapeutic uses of stem cells. Offering a unique compilation of articles on the biology and the therapeutic applications of stem cells in the embryonic and mature nervous systems, this volume will be of great value to neuroscientists, developmental biologists, cancer biologists and clinical neurologists.

Regulatory Networks in Stem Cells Book
Score: 3
From 2 Ratings

Regulatory Networks in Stem Cells

  • Author : Vinagolu K. Rajasekhar
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-03-04
  • Genre: Medical
  • Pages : 601
  • ISBN 10 : 1603272275

Regulatory Networks in Stem Cells Excerpt :

Stem cells appear to be fundamental cellular units associated with the origin of multicellular organisms and have evolved to function in safeguarding the cellular homeostasis in organ t- sues. The characteristics of stem cells that distinguish them from other cells have been the fascinating subjects of stem cell research. The important properties of stem cells, such as ma- tenance of quiescence, self-renewal capacity, and differentiation potential, have propelled this exciting ?eld and presently form a common theme of research in developmental biology and medicine. The derivation of pluripotent embryonic stem cells, the prospective identi?cation of multipotent adult stem cells, and, more recently, the induced pluripotent stem cells (popularly called iPS) are important milestones in the arena of stem cell biology. Complex networks of transcription factors, different signaling molecules, and the interaction of genetic and epi- netic events constantly modulate stem cell behavior to evoke programming and reprogramming processes in normal tissue homeostasis during development. In any given cellular scenario, the regulatory networks can pose considerable complexity and yet exert an orderly control of stem cell differentiation during normal development. An aberration in these ?nely tuned processes during development usually results in a spectrum of diseases such as cancers and neurological disorders. Thisunderscorestheimminentneedforamorecompleteunderstandingofmolecular mechanisms underlying the regulatory circuitries required for stem cell maintenance. Overthepast3–5years,adiversegroupofbenchandphysicianscientistshaveprospectively enhanced our knowledge of stem cell biology. These studies are unveiling many unrecognized or previously unknown fundamentals of developmental biology.

Stem Cell Anthology Book

Stem Cell Anthology

  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2009-10-22
  • Genre: Science
  • Pages : 422
  • ISBN 10 : 0123756839

Stem Cell Anthology Excerpt :

The fields of stem cell research, regenerative medicine, tissue engineering, and cloning are very closely related. It is important for researchers in each of these disciplines to be aware of the methods and principles in the others. Elsevier publishes some of the highest individual references in these areas. Bringing together the principles, applications, and basic understanding in these related areas of science will provide a new reference which is serve the needs of a variety of researchers. Edited by Dr. Bruce Carlson, Stem Cell Anthology will be valuable to researchers and students who need to save time and link concepts to principles, applications, and methods in order to work more effectively and see links for potential collaborations. Includes a collection of chapters by leaders in the stem cell field including the first researchers to discover iPS cells and multiple Nobel Laureates Provides the most detailed introduction to basic properties of major embryonic and adult stem cells by highlighting breakthrough discoveries in the nervous system, spinal cord, heart, pancreas, epidermis, musculo-skeletal, retina - leading areas of stem cell research in human application Details technical laboratory set up for practitioners, technicians, and administrators

Adult Neurogenesis Book

Adult Neurogenesis

  • Author : Gerd Kempermann
  • Publisher : Oxford University Press, USA
  • Release Date : 2006
  • Genre: Medical
  • Pages : 464
  • ISBN 10 : 0195179714

Adult Neurogenesis Excerpt :

The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the mature brain. Though we now know that the adult brain can make new neurons, it normally does so only in two privileged regions, the olfactory bulb and the hippocampus. Yet stem cells, which have the potential to produce new neurons, can be found throughout the adult brain. So why does the brain not make wider use of its potential for neurogenesis? And what is the function of new neurons and of neural stem cells in areas where they occur? After all, the brain regenerates poorly and many neurological and psychiatric disorders are chronic because cell replacement has not taken place. This is the first comprehensive, integrated account of one of the most exciting areas of neuroscience. It begins with the historical background and discusses theories of adult neurogenesis and neural stem cell biology in the context of learning and memory processes as well as structural plasticity. It describes in detail neurogenesis in the adult hippocampus and olfactory system and then surveys the regulatory, functional, and comparative aspects, concluding with a chapter on the provocative hypotheses that link failing adult neurogenesis with such diseases as temporal lobe epilepsy, major depression, brain tumors, and dementias. For graduate students, investigators, and clinicians in the neurosciences, developmental biology, and stem cell research, this book is a unique resource that sifts through the evidence for exciting scientific ideas and fosters a realistic view of the therapeutic possibilities for the use of stem cells in the adult brain.

Pluripotent Stem Cell Biology Book

Pluripotent Stem Cell Biology

  • Author : Craig Atwood
  • Publisher : BoD – Books on Demand
  • Release Date : 2014-07-02
  • Genre: Science
  • Pages : 244
  • ISBN 10 : 9789535115908

Pluripotent Stem Cell Biology Excerpt :

Pluripotent stem cells have the potential to revolutionize treatment options for a range of diseases and conditions. This book presents recent advances in our understanding of the biological mechanisms of stem cell self-renewal, reprograming and regeneration. Also covered are novel methodological advances in the culture, purification and use of stem cells, as well as the ethical and moral dilemmas of embryo donation and adoption. These advances will shape the utilization of stem cells for future basic and applied applications.

Novel Targets and Biomarkers in Solid Tumors  2nd Edition Book

Novel Targets and Biomarkers in Solid Tumors 2nd Edition

  • Author : Dong-Hua Yang
  • Publisher : Frontiers Media SA
  • Release Date : 2020-07-16
  • Genre: Uncategoriezed
  • Pages : 285
  • ISBN 10 : 9782889638796

Novel Targets and Biomarkers in Solid Tumors 2nd Edition Excerpt :

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office:

Basic Neurochemistry Book
Score: 5
From 1 Ratings

Basic Neurochemistry

  • Author : Scott Brady
  • Publisher : Academic Press
  • Release Date : 2011-11-02
  • Genre: Science
  • Pages : 1120
  • ISBN 10 : 9780080959016

Basic Neurochemistry Excerpt :

Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, the outstanding and comprehensive classic text on neurochemistry, is now newly updated and revised in its Eighth Edition. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences. The text has evolved, as intended, with the science. It is also an excellent source of current information on basic biochemical and cellular processes in brain function and neurological diseases for continuing medical education and qualifying examinations. This text continues to be the standard reference and textbook for exploring the translational nature of neuroscience, bringing basic and clinical neuroscience together in one authoritative volume. Our book title reflects the expanded attention to these links between neurochemistry and neurologic disease. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from: Intracellular trafficking; Stem cells, adult neurogenesis, regeneration; Lipid messengers; Expanded coverage of all major neurodegenerative and psychiatric disorders; Neurochemistry of addiction; Neurochemistry of pain; Neurochemistry of hearing and balance; Neurobiology of learning and memory; Sleep; Myelin structure, development, and disease; Autism; and Neuroimmunology. Completely updated text with new authors and material, and many entirely new chapters Over 400 fully revised figures in splendid color 61 chapters covering the range of cellular, molecular and medical neuroscience Translational science boxes emphasizing the connections between basic and clinical neuroscience Companion website at

Endocrine Involvement in Developmental Syndromes Book

Endocrine Involvement in Developmental Syndromes

  • Author : Marco Cappa
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2009-01-01
  • Genre: Medical
  • Pages : 195
  • ISBN 10 : 9783805590419

Endocrine Involvement in Developmental Syndromes Excerpt :

In recent years a significant improvement in the understanding of genetics and developmental syndromes has been seen. In this context, the study of endocrinological aspects in patients with genetic syndromes is acquiring increasing significance.This book documents a workshop held in Rome in April 2008 and presents recent advances in the study of developmental syndromes and epigenetics. Contributions by international experts focus on the genetic aspects of Beckwith-Wiedemann, Silver-Russel, Prader-Willi and Angelman syndromes and many more.Providing an eclectic update on the endocrine involvement in developmental syndromes, this book will be of interest to clinicians and researchers in endocrinology, pediatrics and genetics.

Development of the Ocular Lens Book

Development of the Ocular Lens

  • Author : Frank J. Lovicu
  • Publisher : Cambridge University Press
  • Release Date : 2004-09-15
  • Genre: Medical
  • Pages : 436
  • ISBN 10 : 0521838193

Development of the Ocular Lens Excerpt :

Publisher Description

Advances in Vision Research  Volume III Book

Advances in Vision Research Volume III

  • Author : Gyan Prakash
  • Publisher : Springer Nature
  • Release Date : 2021-02-18
  • Genre: Medical
  • Pages : 478
  • ISBN 10 : 9789811591846

Advances in Vision Research Volume III Excerpt :

This third volume, with three supporting editors, broadens its focus on genetic eye research from the Asian to the global scale. New efforts and a new awareness have sparked important discussions on genetic eye research, and new plans are being implemented to identify the genes responsible for numerous eye diseases. The book introduces the latest findings on genetics in eye diseases, gene therapy, and genome-wide association analysis, and the efforts of the Global Eye Genetic Consortium (GEGC). The book’s editors have been instrumental in developing strategies for discovering the new genes involved in many eye diseases. All chapters were written by leading researchers working on eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume III is a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases around the globe.