Stem Cell and Gene Therapy for Cardiovascular Disease Book

Stem Cell and Gene Therapy for Cardiovascular Disease


  • Author : Emerson C. Perin
  • Publisher : Academic Press
  • Release Date : 2015-08-21
  • Genre: Science
  • Pages : 538
  • ISBN 10 : 9780128018637

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Stem Cell and Gene Therapy for Cardiovascular Disease Excerpt :

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body’s natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

Cardiac Regeneration Book

Cardiac Regeneration


  • Author : Masaki Ieda
  • Publisher : Springer
  • Release Date : 2017-10-27
  • Genre: Medical
  • Pages : 274
  • ISBN 10 : 9783319561066

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Cardiac Regeneration Excerpt :

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

Gene Therapy for Cardiovascular Diseases and Arrhythmia Book

Gene Therapy for Cardiovascular Diseases and Arrhythmia


  • Author : Kamilla Kelemen
  • Publisher : Nova Science Publishers
  • Release Date : 2012
  • Genre: Arrhythmia
  • Pages : 178
  • ISBN 10 : 1619427540

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Gene Therapy for Cardiovascular Diseases and Arrhythmia Excerpt :

Cardiovascular disease has evolved into an epidemic health concern. During the past decades, considerable effort has been made to develop novel and safer therapeutic options. Gene therapy has offered much renewed hope and instigated the present book. For the treatment of cardiovascular disease gene therapy has risen to an interesting and important point of view of curing disease. Although most of the studies are still experimental beneath a well defined number of clinical studies, more and more studies are designed to be carried out in humans. Based on a rich compilation of scientific as well as clinical studies around the world, this book gives insights into the general principles of gene transfer as well as therapeutic strategies including stem cell therapy as an alternative approach to gene therapy.

Stem Cell and Gene Based Therapy Book

Stem Cell and Gene Based Therapy


  • Author : Alexander Battler
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-06-26
  • Genre: Medical
  • Pages : 460
  • ISBN 10 : 184628676X

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Stem Cell and Gene Based Therapy Excerpt :

Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Gene Therapy for Cardiovascular Diseases and Arrhythmia Book

Gene Therapy for Cardiovascular Diseases and Arrhythmia


  • Author : Kamilla Kelemen
  • Publisher : Nova Biomedical
  • Release Date : 2012
  • Genre: Medical
  • Pages : 166
  • ISBN 10 : 1619427419

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Gene Therapy for Cardiovascular Diseases and Arrhythmia Excerpt :

Cardiovascular disease has evolved into an epidemic health concern. During the past decades, considerable effort has been made to develop novel and safer therapeutic options. Gene therapy has offered much renewed hope and instigated the present book. For the treatment of cardiovascular disease gene therapy has risen to an interesting and important point of view of curing disease. Although most of the studies are still experimental beneath a well defined number of clinical studies, more and more studies are designed to be carried out in humans. Based on a rich compilation of scientific as well as clinical studies around the world, this book gives insights into the general principles of gene transfer as well as therapeutic strategies including stem cell therapy as an alternative approach to gene therapy.

Targets in Gene Therapy Book

Targets in Gene Therapy


  • Author : Yongping You
  • Publisher : BoD – Books on Demand
  • Release Date : 2011-08-23
  • Genre: Medical
  • Pages : 448
  • ISBN 10 : 9789533075402

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Targets in Gene Therapy Excerpt :

This book aims at providing an up-to-date report to cover key aspects of existing problems in the emerging field of targets in gene therapy. With the contributions in various disciplines of gene therapy, the book brings together major approaches: Target Strategy in Gene Therapy, Gene Therapy of Cancer and Gene Therapy of Other Diseases. This source enables clinicians and researchers to select and effectively utilize new translational approaches in gene therapy and analyze the developments in target strategy in gene therapy.

Applications of Biotechnology in Cardiovascular Therapeutics Book

Applications of Biotechnology in Cardiovascular Therapeutics


  • Author : Kewal K. Jain
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-07-25
  • Genre: Science
  • Pages : 350
  • ISBN 10 : 1617792403

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Applications of Biotechnology in Cardiovascular Therapeutics Excerpt :

For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease. This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient. Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.

Molecular Cardiology Book

Molecular Cardiology


  • Author : Zhongjie Sun
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-02-01
  • Genre: Medical
  • Pages : 419
  • ISBN 10 : 9781592598793

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Molecular Cardiology Excerpt :

The aim of Molecular Cardiology: Methods and Protocols is to document state-of-the-art molecular and genetic techniques in the area of cardiology. These modern approaches enable researchers to readily study heart diseases at the molecular level and will promote the development of new therapeutic str- egies. Methods for genetic dissection, signal transduction, and microarray analysis are excellent tools for the study of the molecular mechanisms of cardiovascular diseases. Protocols for transgenesis take advantage of recent advances in many areas of molecular and cell biology. Transgenic models of heart diseases (cardiac hypertrophy, cardiac dysfunction, and so on. ) are powerful tools for the study of heart disease pathogenesis. Methods for gene transfer to heart tissue using viral and nonviral vectors form the basis of gene therapy for heart diseases. Heart-specific promoters containing a hypox- inducible cardioprotective gene switch are key for protection of the heart from ischemia. Gene and stem cell therapies open novel and exciting avenues for the prevention and treatment of heart diseases. Molecular Cardiology: Methods and Protocols consists of 26 chapters de- ing with various aspects of molecular cardiology, including gene transfer and gene therapy for cardiovascular disease, stem cell therapy for cardiovascular disease, gene analysis in the injured and hypertrophied heart, and transgenesis in cardiovascular research. This book provides step-by-step methods for the successful completion of experimental procedures, and would be useful for both experienced and new investigators in the field of molecular cardiology.

Stem Cells Book

Stem Cells


  • Author : Khawaja H. Haider
  • Publisher : Springer Nature
  • Release Date : 2022-01-01
  • Genre: Science
  • Pages : 255
  • ISBN 10 : 9783030770525

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Stem Cells Excerpt :

In this volume, the contributing authors from top labs involved in stem cell theranostics share the latest advances in the field of stem cell research. The book covers many aspects of stem cell-based therapy and the progress made toward stem cell therapy for liver, ocular, and cardiovascular diseases as well as cancer. This volume serves as a continuation of Prof. Khawaja Husnain Haider’s previously edited books pertaining to stem cells-based therapnostics. This is an ideal book for researchers involved in drug development as well as regenerative medicine and stem cell-based therapy. The secondary audience includes graduate and postgraduate medical students, doctors, cellular pharmacology, drug industry, and researchers involved in using stem cells as ex-vivo disease models for drug development.

Stem Cells in Clinical Practice and Tissue Engineering Book

Stem Cells in Clinical Practice and Tissue Engineering


  • Author : Rakesh Sharma
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-05-02
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9781789230109

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Stem Cells in Clinical Practice and Tissue Engineering Excerpt :

Stem Cells in Clinical Practice and Tissue Engineering is a concise book on applied methods of stem cell differentiation and optimization using tissue engineering methods. These methods offer immediate use in clinical regenerative medicine. The present volume will serve the purpose of applied stem cell differentiation optimization methods in clinical research projects, as well as be useful to relatively experienced stem cell scientists and clinicians who might wish to develop their stem cell clinical centers or research labs further. Chapters are arranged in the order of basic concepts of stem cell differentiation, clinical applications of pluripotent stem cells in skin, cardiac, bone, dental, obesity centers, followed by tissue engineering, new materials used, and overall evaluation with their permitted legal status.

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair Book

Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair


  • Author : Nabil Dib
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-04-09
  • Genre: Technology & Engineering
  • Pages : 335
  • ISBN 10 : 9780387309392

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Stem Cell Therapy and Tissue Engineering for Cardiovascular Repair Excerpt :

In excess of 7 million people worldwide die of coronary heart disease each year. Only one-third of these heart attack victims recover completely. The remainder suffer the consequences of myocardial infarction and its ill fated remodeling process, resulting in chronic congestive heart failure. This malady alone is the leading cause of hospital admissions in the United States. New breakthroughs in stem cell therapy and tissue engineering have promised to reverse this dismal outcome by cardiovascular repair. World authorities, including scientists and regulatory authorities, have joined in a collaborative effort to present for the reader the first collective review of stem cell therapy for the treatment of cardiovascular disease. These contributions in basic science, pre-clinical and clinical experience guided by the regulatory pathways, assure a rapid course of translational research and clinical trials. The contents of this publication will become a prerequisite for those preparing to meet the challenges of this exciting and potentially rewarding field of stem cell research.

Emerging Trends in Cell and Gene Therapy Book

Emerging Trends in Cell and Gene Therapy


  • Author : Michael K. Danquah
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-14
  • Genre: Science
  • Pages : 705
  • ISBN 10 : 9781627034173

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Emerging Trends in Cell and Gene Therapy Excerpt :

Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: · Biological aspects of stem cell sources, differentiation and engineering. · Application of microfluidics to study stem cell dynamics · Potential clinical application of stem cells and gene therapy to specific human disease. · Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. · Biomimetic multiscale topography for cell alignment.

Stem Cells Book

Stem Cells


  • Author : Christine Mummery
  • Publisher : Academic Press
  • Release Date : 2014-05-23
  • Genre: Science
  • Pages : 448
  • ISBN 10 : 9780124115675

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Stem Cells Excerpt :

The second edition of Stem Cells: Scientific Facts and Fiction provides the non-stem cell expert with an understandable review of the history, current state of affairs, and facts and fiction of the promises of stem cells. Building on success of its award-winning preceding edition, the second edition features new chapters on embryonic and iPS cells and stem cells in veterinary science and medicine. It contains major revisions on cancer stem cells to include new culture models, additional interviews with leaders in progenitor cells, engineered eye tissue, and xeno organs from stem cells, as well as new information on "organs on chips" and adult progenitor cells. In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues that everyone presumed were unable to regenerate in adults, the heart and the brain in particular. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson's, diabetes, and spinal cord lesions, based on the use of stem cells; and from entrepreneurs in biotechnology who expect new commercial applications ranging from drug discovery to transplantation therapies. Explains in straightforward, non-specialist language the basic biology of stem cells and their applications in modern medicine and future therapy Includes extensive coverage of adult and embryonic stem cells both historically and in contemporary practice Richly illustrated to assist in understanding how research is done and the current hurdles to clinical practice