Mesenchymal Stem Cells in Human Health and Diseases Book
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Mesenchymal Stem Cells in Human Health and Diseases


  • Author : Ahmed El-Hashash
  • Publisher : Academic Press
  • Release Date : 2020-01-06
  • Genre: Science
  • Pages : 228
  • ISBN 10 : 9780128197134

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Mesenchymal Stem Cells in Human Health and Diseases Excerpt :

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Stem Cell Innovation in Health   Disease  The Lung  Volume 2 Book

Stem Cell Innovation in Health Disease The Lung Volume 2


  • Author : Ahmed El-Hashash
  • Publisher : Academic Press
  • Release Date : 2021-06-10
  • Genre: Medical
  • Pages : 174
  • ISBN 10 : 9780128212073

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Stem Cell Innovation in Health Disease The Lung Volume 2 Excerpt :

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the

Stem Cell Research and the Collaborative Regulation of Innovation Book

Stem Cell Research and the Collaborative Regulation of Innovation


  • Author : Sarah Devaney
  • Publisher : Routledge
  • Release Date : 2013-12-13
  • Genre: Law
  • Pages : 218
  • ISBN 10 : 9781136014482

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Stem Cell Research and the Collaborative Regulation of Innovation Excerpt :

Hopes are high that stem cell (SC) research will lead to treatments and cures for some of the most serious diseases affecting humankind today. SC science has been used in a treatment setting in the replacement of patients’ windpipes and in restoring sight to patients who were blind in one eye and in future it is hoped that when the body is injured it will be able to be stimulated to produce those types of SCs necessary to repair the particular damage caused. In the meantime, research into specific treatments for a wide range of serious conditions is being undertaken including Alzheimer’s disease, cancer, and diabetes. The book considers the regulatory governance of stem cell research, setting out a readily understandable account of the science and the challenges it poses for regulators as the research is increasingly being clinically applied. It provides a critical account of those elements of a regulatory system which will be required for any jurisdiction aiming to facilitate innovative and productive SC research while maintaining appropriate ethical and legal controls. The book addresses the specific failings in the current regulatory approach to SC research in the UK and goes on to look at the regulatory approaches in the US. The book systematically analyses the roles and responsibilities of the three key participants who collaborate in this process: regulators, scientists and tissue providers, arguing that a regulatory system which fails to recognise and facilitate the vital role which each of these three groups plays runs the risk of impairing the chances of the hopes for SC research being realised. The book places a particular emphasis on ensuring that those who contribute their bodily tissues to this endeavour are treated fairly, involving a recognition that their tissues are their property.

Addressing Sickle Cell Disease Book

Addressing Sickle Cell Disease


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2021-01-22
  • Genre: Medical
  • Pages : 522
  • ISBN 10 : 9780309669603

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Addressing Sickle Cell Disease Excerpt :

Sickle cell disease (SCD) is a genetic condition that affects approximately 100,000 people in the United States and millions more globally. Individuals with SCD endure the psychological and physiological toll of repetitive pain as well as side effects from the pain treatments they undergo. Some adults with SCD report reluctance to use health care services, unless as a last resort, due to the racism and discrimination they face in the health care system. Additionally, many aspects of SCD are inadequately studied, understood, and addressed. Addressing Sickle Cell Disease examines the epidemiology, health outcomes, genetic implications, and societal factors associated with SCD and sickle cell trait (SCT). This report explores the current guidelines and best practices for the care of patients with SCD and recommends priorities for programs, policies, and research. It also discusses limitations and opportunities for developing national SCD patient registries and surveillance systems, barriers in the healthcare sector associated with SCD and SCT, and the role of patient advocacy and community engagement groups.

The Lung Book

The Lung


  • Author : Ahmed El-Hashash
  • Publisher : Elsevier
  • Release Date : 2021-06-29
  • Genre: Medical
  • Pages : 174
  • ISBN 10 : 9780128212066

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The Lung Excerpt :

In the lung, more recent data have been accumulated on lung stem cell biology/function and the potential applications of stem cells in pulmonary diseases that are facilitated by the recent development of a broad range of cutting edge in vitro and in vivo research tools and approaches, including mouse and human organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 2: The Lung, contains two major sections describing cutting edge research for understanding stem cell functions in the lung and respiratory system, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model lung diseases, through the cutting-edge research aiming to bring stem cells from bench to bedside, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of lung diseases/disorders. This book, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the lung in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand respiratory stem cell functions and develop methods to bring stem cells from bench to bedside for different lung diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and iPSC-derived alveolar epithelia cell therapy in the lung Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific to the

The Intestine Book

The Intestine


  • Author : Ahmed El-Hashash
  • Publisher : Academic Press
  • Release Date : 2021-06-15
  • Genre: Science
  • Pages : 204
  • ISBN 10 : 9780128212714

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The Intestine Excerpt :

The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world. Provides intensive scientific background and most recent information on cutting edge research to understand intestinal stem cell functions and develop methods to bring stem cells from bench to bedside for different intestinal diseases Analyzes the current state, opportunities, and challenges of innovative technologies and stem cells from bench to bed, including organoids and the CRISPR gene editing system in the intestine Contains two major sections describing cutting-edge research for understanding stem cell functions and for developing methods specific t

Stem Cell Therapies Book

Stem Cell Therapies


  • Author : National Research Council
  • Publisher : National Academies Press
  • Release Date : 2014-06-18
  • Genre: Medical
  • Pages : 108
  • ISBN 10 : 9780309303033

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Stem Cell Therapies Excerpt :

Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson's disease, diabetes, and spinal cord injury. Clinical trials of stem cell treatments are under way in countries around the world, but the evidence base to support the medical use of stem cells remains limited. Despite this paucity of clinical evidence, consumer demand for treatments using stem cells has risen, driven in part by a lack of available treatment options for debilitating diseases as well as direct-to-consumer advertising and public portrayals of stem cell-based treatments. Clinics that offer stem cell therapies for a wide range of diseases and conditions have been established throughout the world, both in newly industrialized countries such as China, India, and Mexico and in developed countries such as the United States and various European nations. Though these therapies are often promoted as being established and effective, they generally have not received stringent regulatory oversight and have not been tested with rigorous trials designed to determine their safety and likely benefits. In the absence of substantiated claims, the potential for harm to patients - as well as to the field of stem cell research in general - may outweigh the potential benefits. To explore these issues, the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research held a workshop in November 2013. Stem Cell Therapies summarizes the workshop. Researchers, clinicians, patients, policy makers, and others from North America, Europe, and Asia met to examine the global pattern of treatments and products being offered, the range of patient experiences, and options to maximize the well-being of patients, either by protecting them from treatments that are dangerous or i

Joint and Bone Book

Joint and Bone


  • Author : Deming Jiang
  • Publisher : Academic Press
  • Release Date : 2022-09-15
  • Genre: Science
  • Pages : 200
  • ISBN 10 : 0323919383

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Joint and Bone Excerpt :

Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside. Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases. Provides cutting-edge research needed to understand stem cell functions in joint and bone diseases Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in the joint and bone

Stem Cell Tourism and the Political Economy of Hope Book

Stem Cell Tourism and the Political Economy of Hope


  • Author : Alan Petersen
  • Publisher : Springer
  • Release Date : 2017-01-12
  • Genre: Social Science
  • Pages : 218
  • ISBN 10 : 9781137470430

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Stem Cell Tourism and the Political Economy of Hope Excerpt :

This book provides a unique and innovative perspective on the controversial phenomenon of ‘stem cell tourism’. A growing number of patients are embarking on stem cell treatments that are clinically unproven and yet available in clinics and hospitals around the world. The authors offer a cutting-edge multi-dimensional perspective on this complex and rapidly changing phenomenon, including an analysis of the experiences of those who have undertaken or have contemplated undertaking a stem cell treatment, as well as examination of the views of those who undertake research or advise on or provide stem cell treatments. Developing the concept of ‘the political economy of hope’, and referencing case studies of the stem cell treatment market in China, Germany, and Australia, this book argues for a reframing of ‘stem cell tourism’ to understand why patients and families pursue these treatments and whether authorities’ concerns are justified and whether their responses are appropriate and proportionate to the alleged risks.

Handbook of Innovations in Central Nervous System Regenerative Medicine Book

Handbook of Innovations in Central Nervous System Regenerative Medicine


  • Author : Antonio Salgado
  • Publisher : Elsevier
  • Release Date : 2020-06-10
  • Genre: Medical
  • Pages : 710
  • ISBN 10 : 9780128180853

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Handbook of Innovations in Central Nervous System Regenerative Medicine Excerpt :

Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Gendered Innovation in Health and Medicine Book

Gendered Innovation in Health and Medicine


  • Author : Londa Schiebinger
  • Publisher : Unknown
  • Release Date : 2015
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : OCLC:1129785865

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Gendered Innovation in Health and Medicine Excerpt :

Abstract: "'Gendered Innovations' integrates sex and gender analysis into all phases of biomedical and health research to assure excellence and quality in outcomes. This article reports on the interdisciplinary, international collaboration that produced: 1) state-of-the-art methods of sex and gender analysis for health and medicine; and 2) case studies to illustrate how gender analysis leads to discovery in biomedicine and better outcomes in health research: osteoporosis research in men, the genetics of sex determination, heart disease in women, stem cell research, animal research, nutrigenomics and degendering knee implants. The article concludes with a short review of policy at the Canadian, US, and European institutes of health, medical curricula, and policies for peer-reviewed journals in relation to reporting sex/gender analysis in research." (Autorenreferat)

The Delivery of Regenerative Medicines and Their Impact on Healthcare Book

The Delivery of Regenerative Medicines and Their Impact on Healthcare


  • Author : Catherine Prescott
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Genre: Law
  • Pages : 400
  • ISBN 10 : 9781439836071

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The Delivery of Regenerative Medicines and Their Impact on Healthcare Excerpt :

Now that prohibitions against stem cell research are relaxing, it is time for the field to move forward with the advances that promise to eliminate so much human suffering. However, it would be naïve to ignore the fact that regenerative medicines pose a whole new set of challenges to an industry sector that for decades has geared itself to the development and delivery of traditional pharmaceuticals. Still, significant strides are being made. Unique in its focus, The Delivery of Regenerative Medicines and Their Impact on Healthcare delves into material not included in other books. Edited by Dr. Catherine Prescott and Professor Dame Julia Polak, two of the most respected authorities in stem cell research and the business of regenerative medicine, this text presents original firsthand accounts of experts from around the globe. Professor Polak starts by summarizing the progress made and the challenges currently facing the field both as a science and an emerging industry. This is followed by topics relevant to regulators, insurers, and investors as well as pharmaceutical and biotech researchers. Offering innovative insight on topics rarely covered, this volume: Details various innovative investment models Offers a detailed overview of cell-based products and therapeutic stem cell technologies Examines concerns over safeguarding intellectual property Looks at evolving regulations in the U.S. and Europe Discusses insurance and risk management and the establishment of reimbursement parameters This book reaches out to inform a wide audience across government, industry, and academia. It goes beyond the usual discussions to help invigorate the dialogue and present solutions that must occur at the crossroads of technology and commerce for regenerative medicines to realize their promise.

Stem Cells and Regenerative Medicine Book

Stem Cells and Regenerative Medicine


  • Author : Walter C. Low
  • Publisher : World Scientific
  • Release Date : 2008
  • Genre: Electronic books
  • Pages : 551
  • ISBN 10 : 9789812775771

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Stem Cells and Regenerative Medicine Excerpt :

The commercialization of biotechnology has resulted in an intensive search for new biological resources for the purposes of increasing food productivity, medicinal applications, energy production, and various other applications. Although biotechnology has produced many benefits for humanity, the exploitation of the planet's natural resources has also resulted in some undesirable consequences such as diminished species biodiversity, climate change, environmental contamination, and intellectual property right and patent concerns.This book discusses the role of biological, ecological, environmental, ethical, and economic issues in the interaction between biotechnology and biodiversity, using different contexts. No other book has discussed all of these issues in a comprehensive manner. Of special interest is their impact when biotechnology is shared between developed and developing countries, and the lack of recognition of the rights of indigenous populations and traditional farmers in developing countries by large multinational corporations.

Promoting Access to Medical Technologies and Innovation   Intersections between Public Health  Intellectual Property and Trade Book

Promoting Access to Medical Technologies and Innovation Intersections between Public Health Intellectual Property and Trade


  • Author : World Intellectual Property Organization
  • Publisher : WIPO
  • Release Date : 2013
  • Genre: Law
  • Pages : 257
  • ISBN 10 : 9789280523089

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Promoting Access to Medical Technologies and Innovation Intersections between Public Health Intellectual Property and Trade Excerpt :

This study has emerged from an ongoing program of trilateral cooperation between WHO, WTO and WIPO. It responds to an increasing demand, particularly in developing countries, for strengthened capacity for informed policy-making in areas of intersection between health, trade and IP, focusing on access to and innovation of medicines and other medical technologies.

The Fourth Industrial Revolution Book
Score: 3
From 1 Ratings

The Fourth Industrial Revolution


  • Author : Klaus Schwab
  • Publisher : Currency
  • Release Date : 2017
  • Genre: Business & Economics
  • Pages : 184
  • ISBN 10 : 9781524758868

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The Fourth Industrial Revolution Excerpt :

Between the 18th and 19th centuries, Britain experienced massive leaps in technological, scientific, and economical advancement