Mesenchymal Stem Cells in Human Health and Diseases Book

Mesenchymal Stem Cells in Human Health and Diseases


  • Author : Ahmed H.K. El-Hashash
  • Publisher : Academic Press
  • Release Date : 2020-01-07
  • Genre: Science
  • Pages : 228
  • ISBN 10 : 9780128205334

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Mesenchymal Stem Cells in Human Health and Diseases Excerpt :

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

Pluripotent Stem Cells Book

Pluripotent Stem Cells


  • Author : Minoru Tomizawa
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-07-20
  • Genre: Science
  • Pages : 532
  • ISBN 10 : 9789535124719

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Pluripotent Stem Cells Excerpt :

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

Stem Cells and Human Diseases Book

Stem Cells and Human Diseases


  • Author : Rakesh K. Srivastava
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-02-01
  • Genre: Medical
  • Pages : 630
  • ISBN 10 : 9789400728004

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Stem Cells and Human Diseases Excerpt :

The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.

Stem Cells and the Future of Regenerative Medicine Book

Stem Cells and the Future of Regenerative Medicine


  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2002-01-25
  • Genre: Science
  • Pages : 112
  • ISBN 10 : 0309170427

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Stem Cells and the Future of Regenerative Medicine Excerpt :

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush’s watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

iPSCs for Studying Infectious Diseases Book

iPSCs for Studying Infectious Diseases


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-05-29
  • Genre: Science
  • Pages : 332
  • ISBN 10 : 9780128241899

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iPSCs for Studying Infectious Diseases Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs for Studying Infectious Diseases, Volume 8 addresses how important induced pluripotent stems cells are and how can they can help treat certain infectious diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different infectious diseases, such as corona virus, coxsackievirus, salmonella infection, influenza virus and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine, and therapeutics Covers infections by several pathogens, such as coronavirus, coxsackievirus, influenza virus, herpes simplex virus 1, T. gondii, T. cruzi, S. agalactiae, N. meningitidis, Salmonella, and more Is contributed by world-renowned experts in the field

Stem Cells for Cancer and Genetic Disease Treatment Book

Stem Cells for Cancer and Genetic Disease Treatment


  • Author : Phuc Van Pham
  • Publisher : Springer
  • Release Date : 2018-11-07
  • Genre: Science
  • Pages : 190
  • ISBN 10 : 9783319980652

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Stem Cells for Cancer and Genetic Disease Treatment Excerpt :

This invaluable resource discusses insights ranging from basic biological mechanisms of various types of stem cells through the potential applications in the treatment of human diseases, including cancer and genetic disorders. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in understanding different types of stem cell biology and their potential applications in tissue repair and regeneration and in the treatment different types of human cancer and genetic diseases or disorders. Stem Cells for Cancer and Genetic Disease Treatment and the other books in the Stem Cells in Clinical Applicationsseries will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering as well as cancer or genetics research.

Stem Cells and Human Diseases Book

Stem Cells and Human Diseases


  • Author : Rakesh K. Srivastava
  • Publisher : Springer
  • Release Date : 2014-04-17
  • Genre: Medical
  • Pages : 630
  • ISBN 10 : 940178471X

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Stem Cells and Human Diseases Excerpt :

The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell self-renewal, tissue homeostasis and drug resistance are also mentioned. Overall, these reviews will provide a new understanding of the influence of stem cells in tissue regeneration, disease regulation, therapy and drug resistance in several human diseases.

Lung Stem Cells in Development  Health and Disease Book

Lung Stem Cells in Development Health and Disease


  • Author : Nikolic, Marko Z.
  • Publisher : European Respiratory Society
  • Release Date : 2021-04-01
  • Genre: Medical
  • Pages : 392
  • ISBN 10 : 9781849841344

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Lung Stem Cells in Development Health and Disease Excerpt :

Most organs in the adult human body are able to maintain themselves and undergo repair after injury; these processes are largely dependent on stem cells. In this Monograph, the Guest Editors bring together leading authors in the field to provide information about the different classes of stem cells present both in the developing and adult lung: where they are found, how they function in homeostasis and pathologic conditions, the mechanisms that regulate their behaviour, and how they may be harnessed for therapeutic purposes. The book focuses on stem cells in the mouse and human lung but also includes the ferret as an increasingly important new model organism. Chapters also discuss how lung tissue, including endogenous stem cells, can be generated in vitro from pluripotent stem cell lines. This state-of-the-art collection comprehensively covers one of the most exciting areas of respiratory science

Stem Cells and Aging Book

Stem Cells and Aging


  • Author : Surajit Pathak
  • Publisher : Academic Press
  • Release Date : 2021-03-17
  • Genre: Science
  • Pages : 320
  • ISBN 10 : 9780128204139

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Stem Cells and Aging Excerpt :

Stem Cells and Aging covers what is known about the effect of time and age on the basic units of life, which are the corresponding tissue-specific or adult stem cells. Even though the concept of stem cells was introduced nearly a century ago by Alexander Maximow, modern stem-cell research began in 1963 when James Till, Ernest McCullough and Lou Siminovitch established assays to detect hematopoietic stem cells. In fact, given the importance of the aging-associated diseases, scientists have developed a keen interest in understanding the aging process as they attempt to define the role of dysfunctional stem cells in the aging process. With an aging population worldwide, understanding these age-related stem cell changes at a basic biology level and at the level of their influences for regenerative medicine is of interest and importance. There is increasing evidence that the aging process can have much adverse effects on stem cells. In the modern era, one of the emerging fields in treating human diseases is stem cell research, as stem cells have the remarkable potential to treat a wide range of diseases. Nevertheless, understanding the molecular mechanism involved in aging and deterioration of stem cell function is crucial in developing effective new therapies for aging. Serves as an ideal reference to guide investigators toward valuable answers to the problems of our aging population Addresses the effect of time and age on human stem cells Includes chapters from contributors exploring the biology of stem cell aging around the globe

Mesenchymal Stem Cells in Human Health and Diseases Book
Score: 5
From 2 Ratings

Mesenchymal Stem Cells in Human Health and Diseases


  • Author : Ahmed El-Hashash
  • Publisher : Academic Press
  • Release Date : 2020-01-06
  • Genre: Science
  • Pages : 228
  • ISBN 10 : 9780128197134

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Mesenchymal Stem Cells in Human Health and Diseases Excerpt :

Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology. Includes insights ranging from MSC biology and development through the derivation and identification and properties of MSCs Helps to identify potential innovative solutions for restoring normal morphogenesis and/or regeneration of diseased organs Discusses the fact-based promise of MSC therapeutics and regenerative medicine in the real world

iPS Cells for Modelling and Treatment of Human Diseases Book

iPS Cells for Modelling and Treatment of Human Diseases


  • Author : Michael J. Edel
  • Publisher : MDPI
  • Release Date : 2018-10-02
  • Genre: Medical
  • Pages : 422
  • ISBN 10 : 9783038421221

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iPS Cells for Modelling and Treatment of Human Diseases Excerpt :

This book is a printed edition of the Special Issue "iPS Cells for Modelling and Treatment of Human Diseases" that was published in JCM

CRISPR Genome Surgery in Stem Cells and Disease Tissues Book

CRISPR Genome Surgery in Stem Cells and Disease Tissues


  • Author : Stephen H. Tsang
  • Publisher : Academic Press
  • Release Date : 2021-10-20
  • Genre: Science
  • Pages : 136
  • ISBN 10 : 9780128178775

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CRISPR Genome Surgery in Stem Cells and Disease Tissues Excerpt :

CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature. Provides a thorough review of CRISPR-Cas9, from discovery to therapy Covers the latest advances in gene editing and its translational applications to various diseases Written by global leaders in the fields of gene editing and stem cell therapy

Human Stem Cell Manual Book

Human Stem Cell Manual


  • Author : Suzanne Peterson
  • Publisher : Academic Press
  • Release Date : 2012-10-22
  • Genre: Science
  • Pages : 656
  • ISBN 10 : 9780123854742

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Human Stem Cell Manual Excerpt :

This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications. Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America. Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs.

Stem Cell Research and Therapeutics Book

Stem Cell Research and Therapeutics


  • Author : Yanhong Shi
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-07-15
  • Genre: Medical
  • Pages : 326
  • ISBN 10 : 9781402085024

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Stem Cell Research and Therapeutics Excerpt :

This book is an updated reference for one of the most exciting field of biomedical researches- Stem Cell Research and its therapeutic applications. Stem cell research holds great promise for the treatment of many human diseases that currently lack effective therapies. The set of chapters in this book provide insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and li ver degeneration. It also covers novel technologies for the culture and differentiation of both human embryonic stem cells and adult tissue stem cells. This book summarizes our current state of knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine in an overall context. It is an essential reference for students, postdoctoral fellows, academic and industrial scientists, and clinicians. v Acknowledgements The editors would like to thank Ms. Jill Brantley, Rose Chavarin, Alina Haas, and Emily Sun for their administrative assistance and proof-reading of this book. We would also like to thank all the authors for their contributions. vii The editors wish to dedicate this book to our mentors Ron Evans, Fred Gage, and, in memory of Daniel E. Koshland, Jr. Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi 1 Retinal Pigment Epitheli

Stem Cell Epigenetics Book

Stem Cell Epigenetics


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-08-14
  • Genre: Medical
  • Pages : 318
  • ISBN 10 : 9780128140864

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Stem Cell Epigenetics Excerpt :

Stem Cell Epigenetics, Volume 16, examines how epigenetics are involved in stem cell differentiation, how a stem cell rapidly transitions into a molecularly distinct cell type, and how this process may be reversed or managed via epigenetic reprogramming. Topics discussed include chromatin in pluripotency, epigenetic regulation of reprogramming, stem cells and DNA methylation, histone modifications in stem cells and differentiation, higher-order chromatin conformation in pluripotent cells, epigenetics and disease modeling, organoids from pluripotent cells, transcriptional regulation in stem cells and differentiation, non-coding RNAs in pluripotency and early differentiation, and diseases caused by epigenetic alterations in stem cells. Additionally, the potential implementation of stem cell epigenetics in drug discovery, regenerative medicine, and disease treatment is discussed in detail, helping researchers and physicians bring this exciting and fast evolving field to the clinic. Provides genetic researchers, students and physicians with evidence indicating the epigenetic mechanisms involved in stem cell differentiation Highlights the specific characteristics of the epigenetic modifications and misregulations that may result in disease pathogenesis Examines the potential application of stem cell epigenetics towards developing therapeutic interventions for disease and advancing regenerative medicine Features chapter contributions by leading international experts