Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications Book

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications


  • Author : Abdel Salam Hamdy Makhlouf
  • Publisher : Woodhead Publishing
  • Release Date : 2018-06-14
  • Genre: Technology & Engineering
  • Pages : 692
  • ISBN 10 : 9780081019986

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Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications Excerpt :

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications, Volume One: Types and Triggers discusses, in detail, the recent trends in designing biodegradable and biocompatible single-responsive polymers and nanoparticles for safe drug delivery. Focusing on the most advanced materials and technologies, evaluation methods, and advanced synthesis techniques stimuli-responsive polymers, the book is an essential reference for scientists with an interest in drug delivery vehicles. Sections focus on innovation, development and the increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery. Offers an in-depth look at the basic and fundamental aspects of alternative stimuli-responsive polymers, mechanisms, structure, synthesis and properties Provides a well-defined categorization for stimuli-responsive polymers for drug delivery based on different triggering mechanisms Discusses novel approaches and challenges for scaling up and commercialization of stimuli-responsive polymers

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications Book

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications


  • Author : Abdel Salam Hamdy Makhlouf
  • Publisher : Woodhead Publishing
  • Release Date : 2018-10-24
  • Genre: Technology & Engineering
  • Pages : 637
  • ISBN 10 : 9780081019962

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Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications Excerpt :

Stimuli Responsive Polymeric Nanocarriers for Drug Delivery Applications: Volume Two: Advanced Nanocarriers for Therapeutics discusses, in detail, the recent trends in designing dual and multi-responsive polymers and nanoparticles for safe drug delivery. Chapters cover dual-responsive polymeric nanocarriers for drug delivery and their different stimuli, multi-responsive polymeric nanocarriers, and the therapeutic applications of stimuli-responsive polymers. With an emphasis on advanced medical applications and synergistic operational and technological methodologies for the improvement of polymers systems for the production of stimuli-responsive polymers, this book is essential reading for materials scientists and researchers working in the drug delivery and pharmaceutical industries. As innovation and development in the area of stimuli responsive polymer-based nanomaterials for drug delivery is moving fast and there is an increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery, users will find this to be a timely resource. Focusses on the most advanced technologies, recent evaluation methods, technical aspects, and advanced synthesis techniques stimuli-responsive polymers Examines advanced medical applications of stimuli responsive polymers Analyzes synergistic operational and technological methodologies for the improvement of polymer systems for the production of stimuli-responsive polymers in drug delivery

Stimuli Responsive Nanocarriers Book

Stimuli Responsive Nanocarriers


  • Author : Virendra Gajbhiye
  • Publisher : Academic Press
  • Release Date : 2022-01-19
  • Genre: Business & Economics
  • Pages : 484
  • ISBN 10 : 9780323859042

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Stimuli Responsive Nanocarriers Excerpt :

Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics

Smart External Stimulus Responsive Nanocarriers for Drug and Gene Delivery Book

Smart External Stimulus Responsive Nanocarriers for Drug and Gene Delivery


  • Author : Mahdi Karimi
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2015-12-01
  • Genre: Science
  • Pages : 155
  • ISBN 10 : 9781681740102

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Smart External Stimulus Responsive Nanocarriers for Drug and Gene Delivery Excerpt :

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy. This physical energy can be applied from outside the body and can either cause cargo release, or can activate the nanostructure to be cytotoxic, or both. The stimuli covered include light of various wavelengths (ultraviolet, visible or infrared), temperature (increased or decreased), magnetic fields (used to externally manipulate nanostructures and to activate them), ultrasound, and electrical and mechanical forces. Finally we discuss the issue of nanotoxicology and the future scope of the field.

Nanopharmaceutical Advanced Delivery Systems Book

Nanopharmaceutical Advanced Delivery Systems


  • Author : Vivek Dave
  • Publisher : John Wiley & Sons
  • Release Date : 2020-12-29
  • Genre: Computers
  • Pages : 512
  • ISBN 10 : 9781119711681

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Nanopharmaceutical Advanced Delivery Systems Excerpt :

The book provides a single volume covering detailed descriptions about various delivery systems, their principles and how these are put in use for the treatment of multiple diseases. It is divided into four sections where the first section deals with the introduction and importance of novel drug delivery system. The second section deals with the most advanced drug delivery systems like microbubbles, dendrimers, lipid-based nanoparticles, nanofibers, microemulsions etc., describing the major principles and techniques of the preparations of the drug delivery systems. The third section elaborates on the treatments of diverse diseases like cancer, topical diseases, tuberculosis etc. The fourth and final section provides a brief informative description about the regulatory aspects of novel drug delivery system that is followed in various countries.

Smart Pharmaceutical Nanocarriers Book

Smart Pharmaceutical Nanocarriers


  • Author : Torchilin Vladimir P
  • Publisher : World Scientific
  • Release Date : 2015-12-31
  • Genre: Medical
  • Pages : 564
  • ISBN 10 : 9781783267248

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Smart Pharmaceutical Nanocarriers Excerpt :

Drug delivery systems and pharmaceutical nanocarriers that respond to different types of stimuli, such as internal ones, intrinsic for the pathological area (changes in pH, temperature, redox condition, activity of certain enzymes), or external, artificially applied (magnetic field, ultrasound, various irradiations), represent an important and continuously growing area of research. Smart Phramaceutical Nanocarriers overviews the various stimuli used for drug release and delivery by smart pharmaceutical carriers and presents cutting-edge research and the newest data from the leading laboratories in each area.

Drug Targeting and Stimuli Sensitive Drug Delivery Systems Book

Drug Targeting and Stimuli Sensitive Drug Delivery Systems


  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release Date : 2018-05-21
  • Genre: Science
  • Pages : 836
  • ISBN 10 : 9780128136904

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Drug Targeting and Stimuli Sensitive Drug Delivery Systems Excerpt :

Drug Targeting and Stimuli Sensitive Drug Delivery Systems covers recent advances in the area of stimuli sensitive drug delivery systems, providing an up-to-date overview of the physical, chemical, biological and multistimuli-responsive nanosystems. In addition, the book presents an analysis of clinical status for different types of nanoplatforms. Written by an internationally diverse group of researchers, it is an important reference resource for both biomaterials scientists and those working in the pharmaceutical industry who are looking to help create more effective drug delivery systems. Shows how the use of nanomaterials can help target a drug to specific tissues and cells Explores the development of stimuli-responsive drug delivery systems Includes case studies to showcase how stimuli responsive nanosystems are used in a variety of therapies, including camptothecin delivery, diabetes and cancer therapy

Stimuli responsive Drug Delivery Systems Book

Stimuli responsive Drug Delivery Systems


  • Author : Amit Singh
  • Publisher : Royal Society of Chemistry
  • Release Date : 2018-07-09
  • Genre: Technology & Engineering
  • Pages : 360
  • ISBN 10 : 9781788014663

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Stimuli responsive Drug Delivery Systems Excerpt :

The increased understanding of molecular aspects associated with chronic diseases, such as cancer and the role of tumor microenvironment, has led to the identification of endogenous and exogenous stimuli that can be exploited to devise “stimuli-responsive” materials for site-specific drug delivery applications. This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials. Setting the scene, the editors open with a chapter addressing the need for smart materials in delivery applications for therapy, imaging and disease diagnosis. The following chapter describes the key physical and chemical aspects of smart materials, from lipids to polymers to hybrid materials, providing the reader with a springboard to delve into the more application oriented chapters that follow. With in-depth coverage of key drug delivery systems such as pH-responsive, temperature responsive, enzyme-responsive and light responsive systems, this book provides a rigorous foundation to the field. A perfect resource for graduate students and newcomers, the closing chapter on regulatory and commercialization challenges also makes the book ideal for those wanting to take the next step towards clinical translation.

Novel Nanoscale Hybrid Materials Book

Novel Nanoscale Hybrid Materials


  • Author : Bhanu P. S. Chauhan
  • Publisher : John Wiley & Sons
  • Release Date : 2018-02-28
  • Genre: Science
  • Pages : 368
  • ISBN 10 : 9781119156246

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Novel Nanoscale Hybrid Materials Excerpt :

Silanols as building blocks for nanomaterials -- Biomacromolecule enabled synthesis of inorganic materials -- Multilayer assemblies of biopolymers : synthesis, properties, and applications -- Functionalization of p3ht-based hybrid materials for photovoltaic applications -- Insights on nano-filler reinforced polysiloxane hybrids -- Nanophotonics with hybrid nanostructures : new phenomena and new possibilities -- Drug delivery vehicles from stimuli-responsive block copolymers -- Mechanical properties of rubber toughened epoxy nanocomposites -- Metal complexes in reverse micelles -- Heterogenized catalysis on metals impregnated mesoporous silica

Biologically responsive Hybrid Biomaterials Book
Score: 5
From 1 Ratings

Biologically responsive Hybrid Biomaterials


  • Author : Esmaiel Jabbari
  • Publisher : World Scientific
  • Release Date : 2010
  • Genre: Biomedical materials
  • Pages : 423
  • ISBN 10 : 9789814295680

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Biologically responsive Hybrid Biomaterials Excerpt :

Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Stimuli responsive Polymeric Nanoparticles Biomedical Applications Book

Stimuli responsive Polymeric Nanoparticles Biomedical Applications


  • Author : Turgay Yildirim
  • Publisher : Unknown
  • Release Date : 2017
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : OCLC:1007310777

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Stimuli responsive Polymeric Nanoparticles Biomedical Applications Excerpt :

Stimuli-responsive polymeric nanoparticles have recently gained tremendous attention, in particular in the field of controlled drug delivery as a result of offering prolonged circulation times and on demand delivery. The tailor-made design of stimuli-responsive nanoparticles mostly relies on the incorporation of desired stimuli-responsive motifs into the polymers. However, the challenge is to synthesize the corresponding polymers in a well-defined and reproducible way. In the context of the synthesis of stimuli-responsive polymers, the reversible addition fragmentation chain transfer (RAFT) polymerization process is advantageous compared to other techniques due to its high tolerance to various functional groups and polymerization conditions. After the synthesis of the stimuli responsive polymers, it is also crucial to formulate the resulting stimuli-responsive nanoparticles in a controlled way. Nanoprecipitation represents a facile and reliable way to produce polymeric nanoparticles. As a result, the RAFT polymerization process and the nanoprecipitation technique were selected as the methods of choice within this thesis for the synthesis of (multi)functional polymers and the formation of the corresponding nanoparticles. The presented thesis represents an overview of (i) the synthesis of various new stimuli-responsive polymers with tailor-made functionalities and polymer structures, (ii) the formulation of stimuli-responsive nanoparticles via nanoprecipitation, (iii) the investigation of stimuli-responsive behavior of the nanoparticles, as well as (iv) the evaluation of synthesized nanoparticles for drug delivery applications.

Stimuli Responsive Polymers Book

Stimuli Responsive Polymers


  • Author : Navid Rabiee
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2019-06-19
  • Genre: Science
  • Pages : 44
  • ISBN 10 : 9781643276380

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Stimuli Responsive Polymers Excerpt :

This book provides a general introduction to nanogels, and designs of various stimuli-sensitive nanogels that are able to control drug release in response to specific stimuli. Nanogels are three-dimensional nanosized networks that formed by physically or chemically crosslinking polymers. They have highly interesting properties such as biocompatibility, high stability, particle size adjustment, drug loading capability and modification of the surface for active targeting. They can respond to stimuli which results in the controlled release of drug and targeting of the site.

Smart Materials for Drug Delivery Book

Smart Materials for Drug Delivery


  • Author : Carmen Alvarez-Lorenzo
  • Publisher : Royal Society of Chemistry
  • Release Date : 2013-04-17
  • Genre: Technology & Engineering
  • Pages : 394
  • ISBN 10 : 9781849734318

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Smart Materials for Drug Delivery Excerpt :

Smart materials, which can change properties when an external stimulus is applied, can be used for the targeted drug delivery of an active molecule to a specific site in the correct dosage. Different materials such as liposomes, polymeric systems, nanomaterials and hydrogels can respond to different stimuli such as pH, temperature and light and these are all attractive for controlled release applications. With so many papers available on smart and stimuli-responsive materials for drug delivery applications it's hard to know where to start reading about this exciting topic. This two volume set brings together the recent findings in the area and provides a critical analysis of the different materials available and how they can be applied to advanced drug delivery systems. With contributions from leading experts in the field, including a foreword from distinguished scientist Nicholas Peppas, The University of Texas at Austin, USA, the book will provide both an introduction to the key areas for graduate students and new researchers in the stimuli-responsive field as well as serving as a reference for those already working on fundamental materials research or drug delivery applications.

Carbon Nanotubes for Targeted Drug Delivery Book

Carbon Nanotubes for Targeted Drug Delivery


  • Author : Md Saquib Hasnain
  • Publisher : Springer Nature
  • Release Date : 2019-11-08
  • Genre: Technology & Engineering
  • Pages : 106
  • ISBN 10 : 9789811509100

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Carbon Nanotubes for Targeted Drug Delivery Excerpt :

This book provides a detailed introduction to carbon nanotubes (CNTs) for targeted drug delivery. After a brief overview of the classification, preparation, and characterization of carbon nanotubes, it focuses on their use in targeted drug delivery. It presents CNTs for brain targeting, ocular targeting, cancer targeting, and lymphatic targeting, as well as antibody therapy. The book also includes chapters on carbon nanotubes for controlled drug delivery, transdermal drug delivery, solubility enhancement, vaccine delivery, gene delivery, and as quantum dots. Last but not least, it addresses the absorption and transportation of CNTs, toxicity and regulatory considerations, as well as clinical trials and the market status of CNTs. The book offers a comprehensive, self-contained reference guide, with all topics covered concisely and with the help of figures, tables and flowcharts.

Smart Drug Delivery System Book

Smart Drug Delivery System


  • Author : Ali Demir Sezer
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-02-10
  • Genre: Medical
  • Pages : 398
  • ISBN 10 : 9789535122470

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Smart Drug Delivery System Excerpt :

This contribution book collects reviews and original articles from eminent experts working in the interdisciplinary arena of novel drug delivery systems and their uses. From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. On the other hand, this reference discusses advances in the design, optimization, and adaptation of gene delivery systems for the treatment of cancer, cardiovascular, diabetic, genetic, and infectious diseases, and considers assessment and review procedures involved in the development of gene-based pharmaceuticals.