Synapse Development and Maturation Book

Synapse Development and Maturation


  • Author : Pasko Rakic
  • Publisher : Academic Press
  • Release Date : 2020-05-29
  • Genre: Science
  • Pages : 558
  • ISBN 10 : 9780128236734

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Synapse Development and Maturation Excerpt :

Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Includes coverage of mechanisms which regulate synapse formation and maintenance during development Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

From Neurons to Neighborhoods Book
Score: 5
From 1 Ratings

From Neurons to Neighborhoods


  • Author : Division of Behavioral and Social Sciences and Education
  • Publisher : National Academies Press
  • Release Date : 2000-11-13
  • Genre: Social Science
  • Pages : 612
  • ISBN 10 : 9780309069885

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From Neurons to Neighborhoods Excerpt :

How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Discovering the Brain Book

Discovering the Brain


  • Author : National Academy of Sciences
  • Publisher : National Academies Press
  • Release Date : 1992-01-01
  • Genre: Medical
  • Pages : 194
  • ISBN 10 : 9780309045292

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Discovering the Brain Excerpt :

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brain--an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attention--and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniques--what various technologies can and cannot tell us--and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakers--and many scientists as well--with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Cellular Migration and Formation of Neuronal Connections Book

Cellular Migration and Formation of Neuronal Connections


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2013-05-06
  • Genre: Science
  • Pages : 1080
  • ISBN 10 : 9780123973474

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Cellular Migration and Formation of Neuronal Connections Excerpt :

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop Features leading experts in various subfields as Section Editors and article Authors All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.

Development of the Nervous System Book
Score: 4
From 1 Ratings

Development of the Nervous System


  • Author : Dan H. Sanes
  • Publisher : Elsevier
  • Release Date : 2005-11-02
  • Genre: Psychology
  • Pages : 392
  • ISBN 10 : 0080472494

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Development of the Nervous System Excerpt :

Development of the Nervous System, Second Edition has been thoroughly revised and updated since the publication of the First Edition. It presents a broad outline of neural development principles as exemplified by key experiments and observations from past and recent times. The text is organized along a development pathway from the induction of the neural primordium to the emergence of behavior. It covers all the major topics including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, synapse formation and plasticity, and neuronal survival and death. This new text reflects the complete modernization of the field achieved through the use of model organisms and the intensive application of molecular and genetic approaches. The original, artist-rendered drawings from the First Edition have all been redone and colorized to so that the entire text is in full color. This new edition is an excellent textbook for undergraduate and graduate level students in courses such as Neuroscience, Medicine, Psychology, Biochemistry, Pharmacology, and Developmental Biology. Updates information including all the new developments made in the field since the first edition Now in full color throughout, with the original, artist-rendered drawings from the first edition completely redone, revised, colorized, and updated

Biology of the NMDA Receptor Book

Biology of the NMDA Receptor


  • Author : Antonius M. VanDongen
  • Publisher : CRC Press
  • Release Date : 2008-10-29
  • Genre: Science
  • Pages : 350
  • ISBN 10 : 142004415X

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Biology of the NMDA Receptor Excerpt :

The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.

Methods in Neurotransmitter and Neuropeptide Research Book

Methods in Neurotransmitter and Neuropeptide Research


  • Author : S.H. Parvez
  • Publisher : Elsevier
  • Release Date : 2013-10-22
  • Genre: Science
  • Pages : 436
  • ISBN 10 : 9781483290225

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Methods in Neurotransmitter and Neuropeptide Research Excerpt :

This two-part book provides the most advanced biochemical and histochemical analytical methods on neurotransmitters, neuromodulators, and neuropeptides described by international specialists. The biochemical methods include liquid chromatography/electrochemistry, liquid chromatography/fluorescence and chemiluminescence detection, gas chromatography or liquid chromatography with mass spectrometry, and immunoassays. Morphological and physiological methods are also described, including immunohistochemistry, in situ hybridization, in vivo microdialysis, electrophysiological analysis, microwave irradiation, electrophysiological analysis, micro-anatomical dissection, peptide sequence analysis, quantitative autoradiographic analysis, and isolated CNS preparations. The neurotransmitters and neuropeptides include catecholamines, indoleamines, histamine, polyamines, and various neuropeptides, and their related enzymes. The book is the most comprehensive, advanced and versatile volume on the biochemical, morphological and physiological analysis of neurotransmitters and neuropeptides.

Molecular Mechanisms of Neural Development and Insights into Disease Book

Molecular Mechanisms of Neural Development and Insights into Disease


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-03-09
  • Genre: Science
  • Pages : 546
  • ISBN 10 : 9780128152829

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Molecular Mechanisms of Neural Development and Insights into Disease Excerpt :

Neural Development and Disease, Volume 142 in the Current Topics in Developmental Biology series highlights new advances in the field, with this new volume presenting interesting chapters by one or more members of an international board of authors. Sections in this new release cover The role of primary cilia in neural development and disease, Mechanisms of axon guidance receptor regulation and signaling, Synaptic recognition molecules in development and disease, The regulation of cortical neurogenesis, Axon guidance in the developing spinal cord, The role of astrocytes in synapse formation and maturation, Development of motor circuits, Molecular mechanisms that mediate dendrite morphogenesis, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Current Topics in Developmental Biology series

The Synapse Book

The Synapse


  • Author : Virginia M. Pickel
  • Publisher : Elsevier
  • Release Date : 2013-11-16
  • Genre: Science
  • Pages : 512
  • ISBN 10 : 9780124186828

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The Synapse Excerpt :

The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment

The Dynamic Synapse Book

The Dynamic Synapse


  • Author : Josef T. Kittler
  • Publisher : CRC Press
  • Release Date : 2006-03-27
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780203486283

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The Dynamic Synapse Excerpt :

Exploring the diverse tools and technologies used to study synaptic processes, The Dynamic Synapse: Molecular Methods in Ionotropic Receptor Biology delineates techniques, methods, and conceptual advances for studying neurotransmitter receptors and other synaptic proteins. It describes a broad range of molecular, biochemical, imaging, and electrophysiological approaches for studying the biology of synapses. Specific topics include the use of proteomics to study synaptic protein complexes, the development of phosphorylation state specific antibodies, post-genomic tools applied to the study of synapses and RNA interference in neurons. In addition, several chapters focus on methods for gene and protein delivery into neuronal tissue. The use of biochemical, electrophysiological and optical tagging techniques to study the movement and membrane trafficking of neurotransmitter receptors in the membrane of live nerve cells are also discussed. To complement these approaches, the application of approaches for achieving long-term alterations in the genetic complement of neurons in vivo using viral vectors or homologous recombination of ES cells are also described.

Development  Maturation  and Senescence of Neuroendocrine Systems Book

Development Maturation and Senescence of Neuroendocrine Systems


  • Author : Colin Scanes
  • Publisher : Elsevier
  • Release Date : 2012-12-02
  • Genre: Science
  • Pages : 444
  • ISBN 10 : 9780323150125

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Development Maturation and Senescence of Neuroendocrine Systems Excerpt :

Development, Maturation, and Senescence of Neuroendocrine Systems: A Comparative Approach discusses the various phases of the aging continuum of neuroendocrine systems. This book explores the fundamental and physiological component of animals, which is an essential contributor to senescence. Organized into three parts encompassing 21 chapters, this volume starts with a discussion of the concept of neurosecretory neuron that was introduced by Ernst Scharrer in 1928. This book discusses the challenges in the study of the development of the neuroendocrine system in insects, with a focus on Lepidoptera. Other chapters consider the neuroendocrine mechanisms that control the physiological processes in crustaceans. The reader is then introduced to the major neurohemal structures in crustaceans, including the sinus gland, the pericardial organs, and the post-commissural organs. The final chapter discusses the two brain systems that show impact of endogenous steroids that account for subsets of senescent changes. This book is a valuable resource for neurobiologists, molecular biologists, and immunologists.

Developmental Neurobiology Book

Developmental Neurobiology


  • Author : Greg Lemke
  • Publisher : Academic Press
  • Release Date : 2010-05-22
  • Genre: Science
  • Pages : 771
  • ISBN 10 : 0123751675

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Developmental Neurobiology Excerpt :

Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject. The first and only comprehensive, single-volume reference for developmental neuroscience that goes beyond the basic textbook information The 93 chapters cover topics ranging from cell fate determination, path finding, synapse generation, neural stem cells, to neurodegeneration and regeneration, carefully selected from the Encyclopedia of Neuroscience by one of the great developmental neuroscientists, Greg Lemke The best researchers in the field provide their conclusions in the context of the latest experimental results

Neurobehavioral Plasticity Book

Neurobehavioral Plasticity


  • Author : Norman E. Spear
  • Publisher : Psychology Press
  • Release Date : 2013-06-17
  • Genre: Psychology
  • Pages : 490
  • ISBN 10 : 9781134780853

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Neurobehavioral Plasticity Excerpt :

This book describes a unique combination of research programs based on a striking variety of hypotheses and procedures directed toward understanding the sources and consequences of neurobehavioral plasticity. This remarkable attribute of the nervous system -- to be pliable and capable of being shaped or formed by natural or artificial sources toward adaptation or maladaptation -- is considered in terms of the neurochemical forces and neuroanatomical structure that has been found to be pivotal for this function. The impetus for this volume was a symposium held to honor Robert L. Isaacson for his scientific and pedagogical achievements as well as his contributions to behavioral neuroscience. Corresponding to his three major research interests, the book is divided into three sections as follows: * the first explores the relationship between the limbic system and behavior, with an emphasis on learning and memory; * the second considers -- through a wide range of approaches -- issues of plasticity in behavior and brain; and * the third deals with neural and chemical determinants of normal and abnormal behavior. This volume is not only a fitting tribute to Isaacson, but also an unusual collection of new evidence, procedures, and theories destined to have significant influence on behavioral neuroscience.