Systems Biology in Toxicology and Environmental Health Book

Systems Biology in Toxicology and Environmental Health


  • Author : Rebecca Fry
  • Publisher : Academic Press
  • Release Date : 2015-06-11
  • Genre: Medical
  • Pages : 284
  • ISBN 10 : 9780128015681

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Systems Biology in Toxicology and Environmental Health Excerpt :

Systems Biology in Toxicology and Environmental Health uses a systems biological perspective to detail the most recent findings that link environmental exposures to human disease, providing an overview of molecular pathways that are essential for cellular survival after exposure to environmental toxicants, recent findings on gene-environment interactions influencing environmental agent-induced diseases, and the development of computational methods to predict susceptibility to environmental agents. Introductory chapters on molecular and cellular biology, toxicology and computational biology are included as well as an assessment of systems-based tools used to evaluate environmental health risks. Further topics include research on environmental toxicants relevant to human health and disease, various high-throughput technologies and computational methods, along with descriptions of the biological pathways associated with disease and the developmental origins of disease as they relate to environmental contaminants. Systems Biology in Toxicology and Environmental Health is an essential reference for undergraduate students, graduate students, and researchers looking for an introduction in the use of systems biology approaches to assess environmental exposures and their impacts on human health. Provides the first reference of its kind, demonstrating the application of systems biology in environmental health and toxicology Includes introductions to the diverse fields of molecular and cellular biology, toxicology, and computational biology Presents a foundation that helps users understand the connections between the environment and health effects, and the biological mechanisms that link them

Environmental Toxicology Book

Environmental Toxicology


  • Author : Ming-Ho Yu
  • Publisher : CRC Press
  • Release Date : 2000-06-27
  • Genre: Science
  • Pages : 280
  • ISBN 10 : 1439832773

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Environmental Toxicology Excerpt :

How are pollutants transformed after their release into the environment? How are organisms exposed, and how do physiological alterations impact population dynamics and community structure? What direct or indirect impacts occur? As early as the 50s and 60s people living near industrial plants began to recognize undesirable changes in their environment - and to ask these very questions. The discipline of environmental toxicology addresses these questions. Written by an expert with over twenty years experience, Environmental Toxicology covers the physiological and toxicological effects of environmental toxicants on living systems. It explores the sources, and the physical and chemical characteristics of toxicants. It goes further to highlight their impact on plants, animals, and humans. The author furnishes information on the mechanism of action of individual chemicals and chemical combinations including cellular damage at the molecular level. He defines environmental toxicology and discusses the relationship between human activities and their impacts on living systems. He furnishes an overview of our changing environment and the possible link between that environment and the changing pattern of human diseases. Environmental Toxicology provides fundamental knowledge on the toxicological effects of environmental chemicals on living systems. Its fifteen chapters cover the occurrence of toxicants, air pollution, environmental metals, pesticides and related materials such as PCBs and dioxins, mutagenesis, and environmental cancer. This useful resource will enhance your knowledge of the impacts of environmental toxicants on living organisms.

Information Resources in Toxicology Book

Information Resources in Toxicology


  • Author : Steve Gilbert
  • Publisher : Academic Press
  • Release Date : 2020-05-16
  • Genre: Medical
  • Pages : 1054
  • ISBN 10 : 9780128137253

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Information Resources in Toxicology Excerpt :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving incre

Statistics for Environmental Biology and Toxicology Book

Statistics for Environmental Biology and Toxicology


  • Author : A.John Bailer
  • Publisher : Routledge
  • Release Date : 2020-04-03
  • Genre: Mathematics
  • Pages : 584
  • ISBN 10 : 9781351414142

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Statistics for Environmental Biology and Toxicology Excerpt :

Statistics for Environmental Biology and Toxicology presents and illustrates statistical methods appropriate for the analysis of environmental data obtained in biological or toxicological experiments. Beginning with basic probability and statistical inferences, this text progresses through non-linear and generalized linear models, trend testing, time-to-event data and analysis of cross-classified tabular and categorical data. For the more complex analyses, extensive examples including SAS and S-PLUS programming code are provided to assist the reader when implementing the methods in practice.

Environmental Toxicology Book
Score: 5
From 1 Ratings

Environmental Toxicology


  • Author : Ming-Ho Yu
  • Publisher : CRC Press
  • Release Date : 2004-10-28
  • Genre: Science
  • Pages : 368
  • ISBN 10 : 9780203495469

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Environmental Toxicology Excerpt :

An Indispensable Reference of Air, Soil, and Water Pollutants This second edition of Environmental Toxicology focuses on the biological and health effects toxins have on living organisms. It also stresses the relationship between human activity and the environment, relating changes in the environment with the changing patterns of human d

Environmental Toxicology Book

Environmental Toxicology


  • Author : Ming-Ho Yu
  • Publisher : CRC Press
  • Release Date : 2011-11-16
  • Genre: Science
  • Pages : 397
  • ISBN 10 : 9781439840382

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Environmental Toxicology Excerpt :

Human survival depends on the availability of clean air, water, and food and on the welfare of plants and animals. However, anthropogenic and naturally occurring chemicals can cause adverse effects on living organisms and ecological processes. Environmental Toxicology: Biological and Health Effects of Pollutants, Third Edition presents fundamental information on the effects of environmental toxicants on living systems. It focuses on the chemical and biological characteristics of major pollutants found in the air, water, and soil and relates them to the health and well being of humans, animals, and plants. An Indispensable Reference on Air, Soil, & Water Pollutants and Their Impact on Living Systems Surveying the environmental and health changes that have occurred in recent decades, the book discusses the sources, metabolism, and damage process of toxicants, and the environmental, biological, and nutritional factors that may influence toxicity. It looks at natural defense systems, including the mechanisms for detoxification—such as endogenous antioxidants and free radical scavenging enzymes—on a cellular level. The text examines the major toxicants: EPA criteria air pollutants, environmental fluoride, volatile organic compounds (VOCs), environmental metals and metalloids involved in soil and water pollution, and pesticides and related material such as PCBs and dioxins. It then addresses their relationship with endocrine disruption and environmental cancer. This comprehensive approach offers insight into the interaction of various chemical agents with DNA. Fully revised and expanded, the third edition of this popular book includes new and updated material as well as a new chapter on occupational toxicology. Appendices cover the process of ecological risk assessment, carcinogens, and PCB nomenclature. Based on research from more than 35 years of teaching environmental toxicology and related courses, this textbook is a useful resource for students, professionals, an

The Exposome Book

The Exposome


  • Author : Gary W. Miller
  • Publisher : Academic Press
  • Release Date : 2020-06-15
  • Genre: Science
  • Pages : 298
  • ISBN 10 : 9780128140802

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The Exposome Excerpt :

The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and more. Both students and scientists in toxicology, environmental health, epidemiology and public health will benefit from this rigorous, yet readable, overview. This updated edition includes a more in-depth examination of the exposome, including full references, further reading and thought questions. Addresses an emerging field that connects with other exciting disciplines Written by a single author who is a leader in the field Includes new content that widely expands on the first edition

Environmental Health Perspectives Book

Environmental Health Perspectives


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1993
  • Genre: Environmental health
  • Pages : null
  • ISBN 10 : MINN:30000010711616

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Environmental Health Perspectives Excerpt :

Toxicology of Nanoparticles and Nanomaterials in Human  Terrestrial and Aquatic Systems Book

Toxicology of Nanoparticles and Nanomaterials in Human Terrestrial and Aquatic Systems


  • Author : Marc A. Williams
  • Publisher : John Wiley & Sons
  • Release Date : 2022-06-27
  • Genre: Science
  • Pages : 496
  • ISBN 10 : 9781119316374

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Toxicology of Nanoparticles and Nanomaterials in Human Terrestrial and Aquatic Systems Excerpt :

Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems An indispensable compendium detailing the toxicology of nanoparticles with a focus on mechanisms, emerging issues, and new approaches Toxicology of Nanoparticles and Nanomaterials in Human, Terrestrial and Aquatic Systems provides authoritative information on the toxicology of ultrafine and nanoparticulate matter that contaminate terrestrial or aquatic environments and present unique challenges in applied public health and toxicological research. Detailed chapters by a panel of world-renowned experts examine the complementary and dynamic interdependence of aquatic, terrestrial, and human systems and the toxicological impacts on exposure to engineered and manufactured nanoparticles and nanomaterials. Organized into four sections, the book opens with a thorough overview of the field, including known challenges and the necessity for current research activity. The second section describes terrestrial and aquatic systems and the ecotoxicological impact of nanomaterials, followed by critical analysis of the many human health effects of nanomaterials. The book concludes with an in-depth discussion of current gaps in knowledge, future directions, new approach methodologies, alternatives to animal models, and the emerging environmental threat from nanoplastics. Presenting case exemplars of the ecotoxicological impact of nanoparticles in aquatic and terrestrial systems, this important resource: Presents in-depth coverage of ecosafety, environmental behavior, fate and transport, interactive effects with other contaminants, and current challenges in soil nano-ecotoxicology Addresses rising concerns regarding air pollution and neurological disorders, and the roles played by the gastrointestinal system, the mucosal microbiome, and the immunotoxicology and vasculotoxicity of metal-based nanoparticles Provides detailed coverage of nanomaterial health effects from both animal and in vitro models,

Environmental Epigenetics in Toxicology and Public Health Book

Environmental Epigenetics in Toxicology and Public Health


  • Author : Rebecca Fry
  • Publisher : Academic Press
  • Release Date : 2020-10-18
  • Genre: Medical
  • Pages : 364
  • ISBN 10 : 9780128199695

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Environmental Epigenetics in Toxicology and Public Health Excerpt :

Environmental Epigenetics in Toxicology and Public Health provides in-depth discussions of the suite of complex environmental factors shown to impact epigenetic components within the cell, as well as evidence that these epigenetic modifications are tied to early and later life health effects. This book offers a translational research perspective, highlighting both in vivo and human population-based evidence for ties between the environment, the epigenome, and health outcomes, with an emphasis on evidence for transgenerational effects of exposures, as well as developmental windows of susceptibility to environmentally-linked epigenetic effects. This volume in the Translational Epigenetics series aides in the development of new therapeutic options meant to reverse inappropriate epigenetic alterations, helping researchers in their efforts prevent and treat a variety of chronic diseases tied to environmental exposures. Offers a thorough discussion of the environmental factors influencing epigenetic mechanisms in early and late life, and in transgenerational inheritance Examines both animal model and human population-based research in environmental epigenetics, highlighting developmental windows of vulnerability to epigenetic modification Features contributions from international experts in the field

The Exposome Book

The Exposome


  • Author : Gary W. Miller
  • Publisher : Academic Press
  • Release Date : 2020-07-03
  • Genre: Science
  • Pages : 298
  • ISBN 10 : 9780128140796

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The Exposome Excerpt :

The Exposome: A New Paradigm for the Environment and Health, Second Edition, is a thoroughly expanded and updated edition of The Exposome: A Primer, the first book dedicated to the topic. This new release outlines the purpose and scope of this emerging field of study, its practical applications, and how it complements a broad range of disciplines. The book contains sections on -omics-based technologies, newer detection methods, managing and integrating exposome data (including maps, models, computation and systems biology), and more. Both students and scientists in toxicology, environmental health, epidemiology and public health will benefit from this rigorous, yet readable, overview. This updated edition includes a more in-depth examination of the exposome, including full references, further reading and thought questions. Addresses an emerging field that connects with other exciting disciplines Written by a single author who is a leader in the field Includes new content that widely expands on the first edition

A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment Book

A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment


  • Author : Natàlia Garcia-Reyero
  • Publisher : Springer
  • Release Date : 2018-02-24
  • Genre: Science
  • Pages : 422
  • ISBN 10 : 9783319660844

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A Systems Biology Approach to Advancing Adverse Outcome Pathways for Risk Assessment Excerpt :

Social pressure to minimize the use of animal testing, the ever-increasing concern on animal welfare, and the need for more human-relevant and more predictive toxicity tests are some of the drivers for new approaches to chemical screening. This book focuses on The Adverse Outcome Pathway, an analytical construct that describes a sequential chain of causally linked events at different levels of biological organization that lead to an adverse health or ecotoxicological effect. While past efforts have focused on toxicological pathway-based vision for human and ecological health assessment relying on in vitro systems and predictive models, The Adverse Outcome Pathway framework provides a simplified and structured way to organize toxicological information. Within the book, a systems biology approach supplies the tools to infer, link, and quantify the molecular initiating events and the key events and key event relationships leading to adverse outcomes. The advancement of these tools is crucial for the successful implementation of AOPs for regulatory purposes.

Proceedings of 2nd International Conference on Environmental Health   Climate change 2017 Book
Score: 5
From 1 Ratings

Proceedings of 2nd International Conference on Environmental Health Climate change 2017


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2022-07-06
  • Genre: Uncategoriezed
  • Pages : 59
  • ISBN 10 : 978186723xxxx

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Proceedings of 2nd International Conference on Environmental Health Climate change 2017 Excerpt :

September 07-08, 2017 Paris, France Key Topics : Environmental and Occupational health, Environmental Hazards and Human Health, Environmental Toxicology and Health, Environmental sciences and Pollution Research, Environmental Health and Non Communicable Diseases, Environmental Health and Biomedical Waste, Environmental Health and Engineering, Climate Change and Biodiversity, Climate Change and Public Health, Global Climate Change and Health, Climate Change and Water Born Diseases, Climate Change and Zoonotic Diseases, Climate Change and Food Security, Climate Change and Mental Health, Climate Change and Infectious Diseases, Climate Change and Sustainable Goals, Climate Change and Vector Born Diseases, Climate change and Nutrition, Climate Change and Agriculture,

Understanding Toxicology Book

Understanding Toxicology


  • Author : Mercurio
  • Publisher : Jones & Bartlett Publishers
  • Release Date : 2016-08-30
  • Genre: Medical
  • Pages : 952
  • ISBN 10 : 9780763771164

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Understanding Toxicology Excerpt :

While the historic view is that toxicology is the study of poisons, in fact it is just as appropriate to consider modern toxicology as a way of determining new chemotherapies for cancer, microbial diseases, parasites or fungal infections.Biological Toxicology will thoroughly prepare your students for participation in toxicology research. Through a presentation of experimental evidence, students will understand the process for designing and collecting data in biological toxicology research.In five sections, the book examines the foundations of the field, toxic reactions of cells, toxic reactions of tissues/organs, toxic reactions of ecosystems, and biological toxicants.