The Kidney in Systemic Autoimmune Diseases Book

The Kidney in Systemic Autoimmune Diseases


  • Author : Justin C Mason
  • Publisher : Elsevier
  • Release Date : 2007-12-14
  • Genre: Medical
  • Pages : 432
  • ISBN 10 : 008055704X

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The Kidney in Systemic Autoimmune Diseases Excerpt :

This volume brings together an international group of clinicians and clinical scientists to contribute to a state-of the-art review of the underlying pathogenic mechanisms, methods of clinical assessment, classification and diagnosis of renal disease, combined with a detailed overview of treatment strategies. An essential reference source for all those involved with the care of patients with renal involvement in systemic autoimmune disease, and for those contributing to research into the underlying pathogenic mechanisms in these disorders.

Comprehensive Clinical Nephrology E Book Book
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Comprehensive Clinical Nephrology E Book


  • Author : Jurgen Floege
  • Publisher : Elsevier Health Sciences
  • Release Date : 2010-11-08
  • Genre: Medical
  • Pages : 1313
  • ISBN 10 : 9780323081337

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Comprehensive Clinical Nephrology E Book Excerpt :

Comprehensive Clinical Nephrology provides you with all the tools you need to manage all forms of kidney disease. Drs. Jürgen Floege, Richard J. Johnson, John Feehally and a team of international experts have updated this fourth edition to include hot topics such as treatment of hypertensive emergencies, herbal and over-the-counter medicines and the kidney, neurologic complications of the kidney, and more. This essential resource gives you quick access to today’s best knowledge on every clinical condition in nephrology. Make efficient, informed decisions with just the right amount of basic science and practical clinical guidance for every disorder. Diagnose effectively and treat confidently thanks to more than 1100 illustrations, abundant algorithms, and tables that highlight key topics and detail pathogenesis for a full range of kidney conditions and clinical management. Get coverage of the latest developments in the field with 18 new chapters on the Management of the Diabetic Patient with Chronic Kidney Disease, Treatment of Hypertensive Emergencies, Principles of Drug Dosing and Prescribing of Chronic Kidney Disease, Herbal and Over-the-Counter Medicines and the Kidney, Neurologic Complications of the Kidney, and more. Tap into the experience and expertise of the world’s leading authorities in the field of nephrology. Floege, Johnson, and Feehally give you the information you need to make quick and correct clinical decisions

Silva s Diagnostic Renal Pathology Book

Silva s Diagnostic Renal Pathology


  • Author : Xin J. Zhou
  • Publisher : Cambridge University Press
  • Release Date : 2017-03-02
  • Genre: Medical
  • Pages : 691
  • ISBN 10 : 9781316613986

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Silva s Diagnostic Renal Pathology Excerpt :

An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

Podocytopathy Book

Podocytopathy


  • Author : Z.-H. Liui
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2014-05-16
  • Genre: Medical
  • Pages : 277
  • ISBN 10 : 9783318026511

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Podocytopathy Excerpt :

The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.

Janeway s Immunobiology Book

Janeway s Immunobiology


  • Author : Kenneth M. Murphy
  • Publisher : Unknown
  • Release Date : 2008
  • Genre: Immunology
  • Pages : 887
  • ISBN 10 : OCLC:1035926079

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Vascular Manifestations of Systemic Autoimmune Diseases Book

Vascular Manifestations of Systemic Autoimmune Diseases


  • Author : Ronald A. Asherson
  • Publisher : CRC Press
  • Release Date : 2001-01-25
  • Genre: Medical
  • Pages : 624
  • ISBN 10 : 9781420040395

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Vascular Manifestations of Systemic Autoimmune Diseases Excerpt :

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all

Antiphospholipid Syndrome in Systemic Autoimmune Diseases Book

Antiphospholipid Syndrome in Systemic Autoimmune Diseases


  • Author : Ricard Cervera
  • Publisher : Elsevier
  • Release Date : 2016-06-18
  • Genre: Medical
  • Pages : 326
  • ISBN 10 : 9780444636560

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Antiphospholipid Syndrome in Systemic Autoimmune Diseases Excerpt :

Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics. Brings the reader up-to-date and allows easy access to individual topics in one place Written by a respected panel of distinguished physicians/scientists actively involved in the field of Antiphospholipid Syndrome Includes box summaries at the end of each chapter that highlight important topics Gives up-to-date, basic knowledge and a modern approach to diagnosis and therapy Provides a comprehensive review of this major disease Includes information on treatment options available

The Saint Chopra Guide to Inpatient Medicine Book

The Saint Chopra Guide to Inpatient Medicine


  • Author : Sanjay Saint
  • Publisher : Oxford University Press
  • Release Date : 2018-11-09
  • Genre: Medical
  • Pages : 656
  • ISBN 10 : 9780190862824

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The Saint Chopra Guide to Inpatient Medicine Excerpt :

THE DEFINITIVE GUIDE TO INPATIENT MEDICINE, UPDATED AND EXPANDED FOR A NEW GENERATION OF STUDENTS AND PRACTITIONERS A long-awaited update to the acclaimed Saint-Frances Guides, the Saint-Chopra Guide to Inpatient Medicine is the definitive practical manual for learning and practicing inpatient medicine. Its end-to-end coverage of the specialty focuses on both commonly encountered problems and best practices for navigating them, all in a portable and user-friendly format. Composed of lists, flowcharts, and "hot key" clinical insights based on the authors' decades of experience, the Saint-Chopra Guide ushers clinicians through common clinical scenarios from admission to differential diagnosis and clinical plan. It will be an invaluable addition -- and safety net -- to the repertoire of trainees, clinicians, and practicing hospitalists at any stage of their career.

The Lung in Autoimmune Diseases Book

The Lung in Autoimmune Diseases


  • Author : Fabiola Atzeni
  • Publisher : Elsevier
  • Release Date : 2022-02-16
  • Genre: Medical
  • Pages : 228
  • ISBN 10 : 9780323910842

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The Lung in Autoimmune Diseases Excerpt :

The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung’s functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases. Provides a comprehensive review of the different patterns of pulmonary involvement in systemic autoimmune diseases Describes new, targeted therapies for the treatment of systemic autoimmune diseases, including anti-fibrotics, biologics and vasodilators Gives insights on the prognosis of patients suffering from systemic autoimmune diseases Depicts better definitions of types of lung involvement in patients with an underlying systemic autoimmune disease

Pathogenesis of Systemic Lupus Erythematosus Book

Pathogenesis of Systemic Lupus Erythematosus


  • Author : Alberta Hoi
  • Publisher : Springer Nature
  • Release Date : 2021-11-15
  • Genre: Medical
  • Pages : 192
  • ISBN 10 : 9783030851613

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Pathogenesis of Systemic Lupus Erythematosus Excerpt :

The scope of this contributed volume is to provide an overview of the latest translational research in the field of lupus pathogenesis, with particular emphasis on how these discoveries progress in parallel with therapeutic drug development. Systemic lupus erythematosus (SLE) is a multifaceted disease with a number of well-defined immune pathways that are dysregulated, resulting in an immune-mediated chronic inflammatory injury at target organs. As knowledge of these pathways evolves to provide opportunities for targeted drug therapy and lays the foundation for personalized medicine, clinicians and researchers need to keep up with the ever-expanding medical literature. This book will critically appraise the current understanding of important immunological pathways that contribute to the pathogenesis of lupus. We will review the role of interferons as part of the innate immune defects that perpetuate the loss of self-tolerance in SLE. B cell hyperactivity, as a defining hallmark of SLE, and different strategies of B cell targeted therapy will be discussed. The role of co-stimulation or immune checkpoint molecules in activating B and T cells will be reviewed, as well as other cytokines that serve in the amplification loop promoting a more proinflammatory Th1 or Th17 responses. Intracellular targets, such as signaling molecules in the JAK/STAT pathway, or a variety of kinases and proteasomes, can cause a cascading downstream effect of transcriptional responses that are important in SLE. Immune homeostasis can also be restored by bolstering the naturally occurring anti-inflammatory mechanisms. Glucocorticoid, as a potent natural anti-inflammatory hormone, can mediate its effects by recruiting histone deacetylase that serve to repress gene transcription. Glucocorticoid-induced leucine zipper is a gene upregulated by glucocorticoid that can be a potential target for development of anti-inflammatory strategy. Finally, T regulatory cells can be utilized to help restore to i

The Skin in Systemic Autoimmune Diseases Book

The Skin in Systemic Autoimmune Diseases


  • Author : Piercarlo Sarzi-Puttini
  • Publisher : Elsevier
  • Release Date : 2006-01-26
  • Genre: Medical
  • Pages : 358
  • ISBN 10 : 0080461921

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The Skin in Systemic Autoimmune Diseases Excerpt :

This book represents the state-of-the-art in the field of skin and autoimmune rheumatic diseases. It covers systematically a growing and multifaceted topic which is of great importance in the clinical practice. It also serves as a sharp educational tool as each chapter provides summaries and specific highlights to key references cited into the text. The pathophysiological link between skin involvement and autoimmunity has been explained in detail, as well as diagnostic and therapeutic aspects. This book yields an impressive body of well ordered information which summarizes the experience of a selected panel of distinguished physicians and scientists actively involved in the field of skin immunology and systemic autoimmunity. * Written by a respected panel of distinguished physician-scientists actively involved in the field of skin immunology and systemic autoimmunity * Box summaries at the end of each chapter highlight important topics * Up-to-date basic knowledge as well as modern approach to diagnosis and therapy

Autoimmune Disease Models Book

Autoimmune Disease Models


  • Author : Irun R. Cohen
  • Publisher : Academic Press
  • Release Date : 2014-06-28
  • Genre: Medical
  • Pages : 329
  • ISBN 10 : 9780080917368

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Autoimmune Disease Models Excerpt :

Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.

Surgery in Rheumatic and Musculoskeletal Disease Book

Surgery in Rheumatic and Musculoskeletal Disease


  • Author : Fabiola Atzeni
  • Publisher : Elsevier
  • Release Date : 2018-03-26
  • Genre: Medical
  • Pages : 228
  • ISBN 10 : 9780444638885

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Surgery in Rheumatic and Musculoskeletal Disease Excerpt :

Surgery in Systemic Autoimmune Disease, Volume 15, describes the state-of-the-art of the use of surgery in treating the most common systemic autoimmune diseases (SADS). The volume consists of an introductory chapter concerning the impact of surgery on SADs, follow by eight chapters describing the use of surgery in the treatment of specific diseases in various areas (cardiology, gastroenterology, orthopedics, neurology. etc.) and the possible difficulties and complications. The final five chapters deal with the possible complications arising during the course of biological and non-biological treatment, also providing recommendation concerning their management. International in scope, the list of more than 20 contributors from Europa and America reads like a who’s who of clinical researchers in the field. Written by leading international clinical/surgical and scientific experts on surgical problems in SADs Provides a practical guide to the safer use of surgery in patients with autoimmune diseases Includes a number of problems and recommendations that cannot be found in other books Designed as a ‘guide to clinical practice’ for surgical interventions required by patients with SADs Gives a comprehensive review of the available surgical options

Pediatrics in Systemic Autoimmune Diseases Book

Pediatrics in Systemic Autoimmune Diseases


  • Author : Rolando Cimaz
  • Publisher : Elsevier
  • Release Date : 2016-06-08
  • Genre: Medical
  • Pages : 606
  • ISBN 10 : 9780444635976

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Pediatrics in Systemic Autoimmune Diseases Excerpt :

Pediatrics in Systemic Autoimmune Diseases, Second Edition, provides a good starting point for physicians and scientists new to the field and for anyone looking for the most up-to-date summary of a particular disease. While many questions are answered, many more are raised for which we do not yet have the answers. The book provides inspiration to readers conducting their own research and helps to answer their questions. The care of children with systemic autoimmune diseases is moving forward at a rapid pace. The systemic autoimmune diseases of childhood have always represented a special problem for the physicians and scientists who care for the affected children and study their diseases. Some conditions, such as Kawasaki disease, are virtually unique to childhood, while systemic lupus erythematosus, progressive systemic sclerosis, and juvenile onset spondyloarthropathies may be thought of as the early onset of the same disease which is seen in adults. The autoinflammatory disorders appear to be of clear genetic origin, accounting for their frequent discovery in childhood. For many other conditions, such as juvenile dermatomyositis, the relationship between the conditions seen in children and that seen in adults is less certain. This book explores these phenomena, giving users a foundation on which to understand certain diseases. Includes completely updated chapters and five new chapters Explains the differences in systemic autoimmune diseases seen in children vs. those seen in adults Covers the latest advances in pathogenesis and clinical management of common conditions seen in pediatric rheumatology practices, benefiting both pediatric and adult rheumatologists, as well as physicians from other specialties Brings the reader up-to-date and allows easy access to individual topics in one place Provides the latest information available in a format that would give the clinician both a clear understanding of what has been done in the past and a scientific basis for decid