Neurobiology of Bipolar Disorder Book

Neurobiology of Bipolar Disorder


  • Author : Joao Luciano de Quevedo
  • Publisher : Academic Press
  • Release Date : 2020-11-25
  • Genre: Medical
  • Pages : 470
  • ISBN 10 : 9780128191835

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Neurobiology of Bipolar Disorder Excerpt :

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Bipolar Disorder Book

Bipolar Disorder


  • Author : Lakshmi N. Yatham
  • Publisher : John Wiley & Sons
  • Release Date : 2011-06-28
  • Genre: Psychology
  • Pages : 522
  • ISBN 10 : 9781119956228

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Bipolar Disorder Excerpt :

Bipolar disorder is the most complex psychiatric disorder with different types of mood episodes, subtypes, varied course, and significant co-morbidity. Not surprisingly, this complexity poses unique challenges to clinicians for optimal management of those with bipolar disorder. There has been an explosion of research into the causes and treatment of this condition over the past two decades. It is a daunting task for a practising clinician to make sense of this research and to remain up to date with progress in the understanding of the neurobiology and treatment of bipolar disorder. This book synthesizes and translates the vast array of research knowledge into information that is clinically relevant and meaningful for a clinician. The book provides a comprehensive, yet focused, reference work on bipolar disorder for both trainees and practising psychiatrists. The two editors are leaders in the field who have published extensively on bipolar disorder. They have assembled a team of experts from around the world: in many instances, chapters are co-authored by people from different continents, bringing a truly international perspective to this important topic. The book covers the basic science of the pathology underlying bipolar disorder but addresses the clinical aspects of the disease throughout. The book comprises four sections: Descriptive Aspects—issues ranging from how the concept of bipolar disorder has evolved over the years to new information about neurocognitive impairment, creativity and economic productivity, and to discussion of the deliberations of the DSM-V committee on changes in diagnostic categories and criteria. Biology—the contribution of genes to this disorder, changes in circadian rhythms, what we know about brain changes and the role of oxidative stress. Biological Treatment and Psychosocial Treatment— all the latest information about pharmacological and psychological treatments and the optimal management of this condition. If you want to pro

Bipolar Disorder  From Neuroscience to Treatment Book

Bipolar Disorder From Neuroscience to Treatment


  • Author : Allan H. Young
  • Publisher : Springer Nature
  • Release Date : 2021-03-29
  • Genre: Medical
  • Pages : 325
  • ISBN 10 : 9783030721435

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Bipolar Disorder From Neuroscience to Treatment Excerpt :

Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.

The Bipolar Book Book

The Bipolar Book


  • Author : Aysegül Yildiz
  • Publisher : Oxford University Press, USA
  • Release Date : 2015-05-28
  • Genre: Manic-depressive illness
  • Pages : 704
  • ISBN 10 : 9780199300532

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The Bipolar Book Excerpt :

As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Aysegül Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.

Bipolar Disorder in Youth Book

Bipolar Disorder in Youth


  • Author : Stephen M. Strakowski
  • Publisher : Oxford University Press, USA
  • Release Date : 2014-10-29
  • Genre: Medical
  • Pages : 382
  • ISBN 10 : 9780199985357

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Bipolar Disorder in Youth Excerpt :

Bipolar Disorder in Youth provides a timely, focused review of the diagnosis, treatment, and neurobiology of bipolar disorder in youth. The editors and authors of each chapter represent international leaders in the care and study of this population. This book is the most comprehensive volume available discussing this important population and is a 'must' for the libraries of clinicians and scientists working with bipolar children and adolescents.

Bipolar Depression  Molecular Neurobiology  Clinical Diagnosis and Pharmacotherapy Book

Bipolar Depression Molecular Neurobiology Clinical Diagnosis and Pharmacotherapy


  • Author : Carlos A. Zarate Jr.
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-04-16
  • Genre: Medical
  • Pages : 279
  • ISBN 10 : 9783764385675

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Bipolar Depression Molecular Neurobiology Clinical Diagnosis and Pharmacotherapy Excerpt :

Although our knowledge of mood disorders is expanding, comparatively little is known about bipolar depression in particular. This book offers the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression. Early chapters provide diagnostic information and review the course, outcome and genetics of this heritable condition. The book gives a thorough and unique overview of the neurobiology of the disorder, including neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women. Furthermore, the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment, are addressed. Finally, acute and long-term treatment strategies for bipolar depression are discussed, including both traditional and novel therapeutics, as well as non-pharmacological treatments. This volume offers researchers and clinicians key insights into this devastating disorder.

Astrocytes in Psychiatric Disorders Book

Astrocytes in Psychiatric Disorders


  • Author : Baoman Li
  • Publisher : Springer Nature
  • Release Date : 2021-12-09
  • Genre: Medical
  • Pages : 377
  • ISBN 10 : 9783030773755

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Astrocytes in Psychiatric Disorders Excerpt :

This contributed volume discusses the multiple roles of astrocytes, which determine the progression and outcome of neuropsychiatric diseases. This emerging area of study examines the ways in which astrocytes are involved in various aspects of disease initiation, progression and resolution. This monograph aims to integrate the body of information that has accumulated in recent years revealing the active role of astrocytes in neuropsychiatric pathology and in psychiatric disorders. Understanding roles of astrocytes in pathology will provide new targets for medical intervention and aid the development of much needed therapeutics. This book will be valuable for researchers and workers in the fields of neurobiology, neurology, and psychiatry, as well as fill the need for a textbook used in advanced courses/graduate seminars in glial pathophysiology.

The Neurobiological Basis of Suicide Book

The Neurobiological Basis of Suicide


  • Author : Yogesh Dwivedi
  • Publisher : CRC Press
  • Release Date : 2012-06-25
  • Genre: Medical
  • Pages : 482
  • ISBN 10 : 9781439838815

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The Neurobiological Basis of Suicide Excerpt :

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Neurobiology of Depression Book
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Neurobiology of Depression


  • Author : Joao Luciano de Quevedo
  • Publisher : Academic Press
  • Release Date : 2019-01-03
  • Genre: Medical
  • Pages : 471
  • ISBN 10 : 9780128133347

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Neurobiology of Depression Excerpt :

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

Neurobiology of Psychiatric Disorders Book

Neurobiology of Psychiatric Disorders


  • Author : Thomas E. Schlaepfer
  • Publisher : Elsevier
  • Release Date : 2012
  • Genre: Medical
  • Pages : 760
  • ISBN 10 : 9780444520029

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Neurobiology of Psychiatric Disorders Excerpt :

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Behavioral Neurobiology of Bipolar Disorder and its Treatment Book

Behavioral Neurobiology of Bipolar Disorder and its Treatment


  • Author : Husseini K. Manji
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-11-10
  • Genre: Medical
  • Pages : 347
  • ISBN 10 : 9783642157578

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Behavioral Neurobiology of Bipolar Disorder and its Treatment Excerpt :

This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Neuroprogression in Psychiatry Book

Neuroprogression in Psychiatry


  • Author : Flávio Kapczinski
  • Publisher : Oxford University Press
  • Release Date : 2019-03-05
  • Genre: Medical
  • Pages : 272
  • ISBN 10 : 9780191090882

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Neuroprogression in Psychiatry Excerpt :

Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.

Bipolar Disorder in Older Age Patients Book

Bipolar Disorder in Older Age Patients


  • Author : Susan W. Lehmann
  • Publisher : Springer
  • Release Date : 2017-01-05
  • Genre: Medical
  • Pages : 238
  • ISBN 10 : 9783319489124

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Bipolar Disorder in Older Age Patients Excerpt :

This book provides a comprehensive but practical understanding of the clinical approach to evaluating and caring for older people with bipolar disorder. Aspects of aging that impact the diagnosis, clinical course, and management of bipolar disorder are explained; in particular, attention is drawn to the implications of comorbidities and medical complexity for the psychiatric care of older individuals with the disorder. On the other hand, similarities to treatment in younger patients are also identified. The coverage includes thorough review of current research in the field. Clinical case vignettes are used throughout to highlight practical points, and each chapter includes “clinical pearls” that summarize key points for the clinician. The book closes by examining anticipated research directions and the future needs of this patient population. Bipolar Disorder in Older Age Patients will be an ideal update for the practicing community or geriatric psychiatrist working with older patients with bipolar disorder.

Neurobiology of Brain Disorders Book

Neurobiology of Brain Disorders


  • Author : Michael J. Zigmond
  • Publisher : Academic Press
  • Release Date : 2022-05-27
  • Genre: Science
  • Pages : 1134
  • ISBN 10 : 9780323898256

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Neurobiology of Brain Disorders Excerpt :

Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders, Second Edition provides basic scientists a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases. Topics include developmental, autoimmune, central, and peripheral neurodegeneration, infectious diseases, and diseases of higher function. Organized by individual disorder, each chapter includes coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. This volume reflects progress in the field since publication of the first edition, with fully updated chapters, and new chapters on isolation, aging, global diseases, vascular diseases, and toxic/metabolic disease. New disorder coverage includes fibromyalgia, chronic fatigue, Restless Legs Syndrome, myasthenia gravis, and more. Links basic, translational and clinical research on disorders of the nervous system Covers a vast array of neurological and psychiatric disorders, including Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson's, Huntington's, Alzheimer's, OCD, PTSD, schizophrenia, depression and pain Features new chapters on the effects of aging and isolation on brain health Expands coverage on disorders, including new chapters on fibromyalgia, chronic fatigue, and restless legs syndrome Features in-text summary points, special feature boxes and research questions

Mindfulness for Bipolar Disorder Book

Mindfulness for Bipolar Disorder


  • Author : William R. Marchand
  • Publisher : New Harbinger Publications
  • Release Date : 2015-05-01
  • Genre: Self-Help
  • Pages : 232
  • ISBN 10 : 9781626251878

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Mindfulness for Bipolar Disorder Excerpt :

In Mindfulness for Bipolar Disorder, psychiatrist and neuroscientist William R. Marchand provides an innovative,breakthrough program based in neuroscience and mindfulness practices to help you find relief from your bipolar symptoms. If you have bipolar disorder, you may experience feelings of mania or high energy, followed by periods of depression and sadness. These unusual shifts in mood, energy, and activity levels can make it extremely difficult to carry out day-to-day tasks—and ultimately reach your goals. Finding balance may be a daily struggle, even if you are on medication or in therapy. So, what else can you do to start feeling better? Mindfulness—the act of present moment awareness—may be the missing puzzle piece in effectively treating your bipolar disorder. In the book, you will learn how to actively work through feelings of depression, anxiety, and stress in order to improve the quality of your life. Written by a prominent psychiatrist, neuroscientist, and mindfulness teacher who draws upon his research experience and personal mindfulness practice as a monk in the Soto Zen tradition, this book will provide you with the tools needed to get your symptoms under control. If you’ve sought treatment for bipolar disorder but are still struggling with symptoms, mindfulness may be the missing piece to solving the bipolar puzzle and taking back your life. This book will help you get started right away.