The Neuroscience of Cocaine Book

The Neuroscience of Cocaine


  • Author : Victor R. Preedy
  • Publisher : Academic Press
  • Release Date : 2017-05-23
  • Genre: Psychology
  • Pages : 774
  • ISBN 10 : 9780128037928

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The Neuroscience of Cocaine Excerpt :

The Neuroscience of Cocaine: Mechanisms and Treatment explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine’s neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. Written by worldwide experts in cocaine addiction, this book assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Illustrated in full color Provides unique full coverage of all aspects of cocaine and its related pathology Provides researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aids them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms

Never Enough Book
Score: 3
From 1 Ratings

Never Enough


  • Author : Judith Grisel
  • Publisher : Anchor
  • Release Date : 2020-01-14
  • Genre: Psychology
  • Pages : 258
  • ISBN 10 : 9780525434900

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Never Enough Excerpt :

A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial

Advances in the Neuroscience of Addiction Book

Advances in the Neuroscience of Addiction


  • Author : Cynthia M. Kuhn
  • Publisher : CRC Press
  • Release Date : 2010-04-12
  • Genre: Medical
  • Pages : 242
  • ISBN 10 : 9781420007350

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Advances in the Neuroscience of Addiction Excerpt :

Understanding the phenomenon of long-lasting vulnerability to addiction is essential to developing successful treatments. Written by an international team of authorities in their respective fields, Advances in the Neuroscience of Addiction provides an excellent overview of the available and emerging approaches used to investigate the biol

The Neuroscience of Cocaine Book

The Neuroscience of Cocaine


  • Author : Victor R. Preedy
  • Publisher : Academic Press
  • Release Date : 2017-05-01
  • Genre: Uncategoriezed
  • Pages : 608
  • ISBN 10 : 0128037504

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The Neuroscience of Cocaine Excerpt :

Cocaine is one of the most highly abused illicit drugs worldwide and is frequently associated with other forms of drug addiction and misuse, but researchers are still struggling to understand cocaine's neuropharmacological profile and the mechanisms of its effects and manifestations at the cognitive level. Cessation of cocaine use can lead to numerous adverse withdrawal conditions, from the cellular and molecular level to the behavioral level of the individual user. The Neuroscience of Cocaine explores the complex effects of this drug, addressing the neurobiology behind cocaine use and the psychosocial and behavioral factors that impact cocaine use and abuse. This book will provide researchers with an up-to-date understanding of the mechanisms behind cocaine use, and aid them in deriving new pharmacological compounds and therapeutic regimens to treat dependency and withdrawal symptoms. Written by worldwide experts in cocaine addiction, The Neuroscience of Cocaine assists neuroscientists and other addiction researchers in unraveling the many complex facets of cocaine use and abuse. Each chapter contains an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding Comprehensively illustrated in full color The only publication available that provides full coverage of all aspects of cocaine and its related pathology

Neurobiology of Cocaine Addiction Book

Neurobiology of Cocaine Addiction


  • Author : Eric J. Nestler
  • Publisher : DIANE Publishing
  • Release Date : 2008-05
  • Genre: Uncategoriezed
  • Pages : 7
  • ISBN 10 : 9781428988262

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Neurobiology of Cocaine Addiction Excerpt :

Cocaine produces its psychoactive & addictive effects primarily by acting on the brain¿s limbic system, a set of interconnected regions that regulate pleasure & motivation. An initial, short-term effect -- a buildup of the neurochemical dopamine -- gives rise to euphoria & a desire to take the drug again. Researchers are seeking to understand how cocaine¿s many longer term effects produce addiction¿s persistent cravings & risk of relapse. This paper focuses on the buildup of the genetic transcription factor DeltaFosB in the limbic system which correlate with addiction-like behaviors in mice & may precipitate very long-lasting changes to nerve cell structure. This is one of the first steps toward an understanding of the transition from cocaine abuse to addiction.

Methods of Behavior Analysis in Neuroscience Book

Methods of Behavior Analysis in Neuroscience


  • Author : Jerry J. Buccafusco
  • Publisher : CRC Press
  • Release Date : 2000-08-29
  • Genre: Medical
  • Pages : 341
  • ISBN 10 : 9781420041811

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Methods of Behavior Analysis in Neuroscience Excerpt :

Using the most well-studied behavioral analyses of animal subjects to promote a better understanding of the effects of disease and the effects of new therapeutic treatments on human cognition, Methods of Behavior Analysis in Neuroscience provides a reference manual for molecular and cellular research scientists in both academia and the pharmaceutic

Drugs  Addiction  and the Brain Book
Score: 5
From 1 Ratings

Drugs Addiction and the Brain


  • Author : George F. Koob
  • Publisher : Academic Press
  • Release Date : 2014-07-12
  • Genre: Psychology
  • Pages : 350
  • ISBN 10 : 9780123869593

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Drugs Addiction and the Brain Excerpt :

Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Behavioral Neuroscience of Drug Addiction Book

Behavioral Neuroscience of Drug Addiction


  • Author : David W. Self
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-12-18
  • Genre: Medical
  • Pages : 392
  • ISBN 10 : 3642030017

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Behavioral Neuroscience of Drug Addiction Excerpt :

Drug addiction is a chronically relapsing mental illness involving severe motivational disturbances and loss of behavioral control leading to personal dev- tation. The disorder af?icts millions of people, often co-occurring with other mental illnesses with enormous social and economic costs to society. Several decades of research have established that drugs of abuse hijack the brain’s natural reward substrates, and that chronic drug use causes aberrant alterations in these rewa- processing systems. Such aberrations may be demonstrated at the cellular, neu- transmitter, and regional levels of information processing using either animal models or neuroimaging in humans following chronic drug exposure. Behaviorally, these neural aberrations manifest as exaggerated, altered or dysfunctional expr- sion of learned behavioral responses related to the pursuit of drug rewards, or to environmental factors that precipitate craving and relapse during periods of drug withdrawal. Current research efforts are aimed at understanding the associative and causal relationships between these neurobiological and behavioral events, such that treatment options will ultimately employ therapeutic amelioration of neural de?cits and restoration of normal brain processing to promote efforts to abstain from further drug use. The Behavioral Neuroscience of Drug Addiction, part of the Springer series on Current Topics in Behavioral Neurosciences, contains scholarly reviews by noted experts on multiple topics from both basic and clinical neuroscience ?elds.

Neuroscience of Alcohol Book

Neuroscience of Alcohol


  • Author : Victor R. Preedy
  • Publisher : Academic Press
  • Release Date : 2019-03-19
  • Genre: Medical
  • Pages : 736
  • ISBN 10 : 9780128131268

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Neuroscience of Alcohol Excerpt :

Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Drugs and the Neuroscience of Behavior Book

Drugs and the Neuroscience of Behavior


  • Author : Adam Prus
  • Publisher : SAGE Publications
  • Release Date : 2017-02-06
  • Genre: Psychology
  • Pages : 1214
  • ISBN 10 : 9781506338965

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Drugs and the Neuroscience of Behavior Excerpt :

Drugs and the Neuroscience of Behavior: An Introduction to Psychopharmacology, Second Edition by Adam Prus presents an introduction to the rapidly advancing field of psychopharmacology by examining how drug actions in the brain affect psychological processes. The book provides historical background to give readers an appreciation for the development of drug treatments and neuroscience over time, covering major topics in psychopharmacology, including new drugs and recent trends in drug use. Pedagogical features informed by the latest scholarship in teaching and learning are integrated throughout the text to ensure that readers are able to process and understand the material with ease.

Addiction Neuroethics Book
Score: 1
From 1 Ratings

Addiction Neuroethics


  • Author : Adrian Carter
  • Publisher : Academic Press
  • Release Date : 2011-10-04
  • Genre: Psychology
  • Pages : 346
  • ISBN 10 : 9780123859747

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Addiction Neuroethics Excerpt :

Research increasingly suggests that addiction has a genetic and neurobiological basis, but efforts to translate research into effective clinical treatments and social policy needs to be informed by careful ethical analyses of the personal and social implications. Scientists and policy makers alike must consider possible unintended negative consequences of neuroscience research so that the promise of reducing the burden and incidence of addiction can be fully realized and new advances translated into clinically meaningful and effective treatments. This volume brings together leading addiction researchers and practitioners with neuroethicists and social scientists to specifically discuss the ethical, philosophical, legal and social implications of neuroscience research of addiction, as well as its translation into effective, economical and appropriate policy and treatments. Chapters explore the history of ideas about addiction, the neuroscience of drug use and addiction, prevention and treatment of addiction, the moral implications of addiction neuroscience, legal issues and human rights, research ethics, and public policy. Features outstanding and truly international scholarship, with chapters written by leading experts in neuroscience, addiction medicine, psychology and more Informs psychologists of related research in neuroscience and vice versa, giving researchers easy one-stop access to knowledge outside their area of specialty

Drug Use for Grown Ups Book
Score: 3.5
From 4 Ratings

Drug Use for Grown Ups


  • Author : Dr. Carl L. Hart
  • Publisher : Penguin
  • Release Date : 2021-01-12
  • Genre: Social Science
  • Pages : 304
  • ISBN 10 : 9781101981658

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Drug Use for Grown Ups Excerpt :

“Hart’s argument that we need to drastically revise our current view of illegal drugs is both powerful and timely . . . when it comes to the legacy of this country’s war on drugs, we should all share his outrage.” —The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy life Dr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a researcher and professor, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism. Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars. Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of an

The Effects of Drug Abuse on the Human Nervous System Book

The Effects of Drug Abuse on the Human Nervous System


  • Author : Bertha Madras
  • Publisher : Elsevier
  • Release Date : 2013-11-15
  • Genre: Psychology
  • Pages : 624
  • ISBN 10 : 9780124186859

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The Effects of Drug Abuse on the Human Nervous System Excerpt :

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options

An Anatomy of Addiction Book
Score: 4.5
From 2 Ratings

An Anatomy of Addiction


  • Author : Howard Markel
  • Publisher : Vintage
  • Release Date : 2011-07-19
  • Genre: Biography & Autobiography
  • Pages : 336
  • ISBN 10 : 9780307379818

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An Anatomy of Addiction Excerpt :

Acclaimed medical historian Howard Markel traces the careers of two brilliant young doctors—Sigmund Freud, neurologist, and William Halsted, surgeon—showing how their powerful addictions to cocaine shaped their enormous contributions to psychology and medicine. When Freud and Halsted began their experiments with cocaine in the 1880s, neither they, nor their colleagues, had any idea of the drug's potential to dominate and endanger their lives. An Anatomy of Addiction tells the tragic and heroic story of each man, accidentally struck down in his prime by an insidious malady: tragic because of the time, relationships, and health cocaine forced each to squander; heroic in the intense battle each man waged to overcome his affliction. Markel writes of the physical and emotional damage caused by the then-heralded wonder drug, and how each man ultimately changed the world in spite of it—or because of it. One became the father of psychoanalysis; the other, of modern surgery. Here is the full story, long overlooked, told in its rich historical context.

Unbroken Brain Book
Score: 4
From 2 Ratings

Unbroken Brain


  • Author : Maia Szalavitz
  • Publisher : St. Martin's Press
  • Release Date : 2016-04-05
  • Genre: Self-Help
  • Pages : 320
  • ISBN 10 : 9781466859562

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Unbroken Brain Excerpt :

A NEW YORK TIMES BESTSELLER More people than ever before see themselves as addicted to, or recovering from, addiction, whether it be alcohol or drugs, prescription meds, sex, gambling, porn, or the internet. But despite the unprecedented attention, our understanding of addiction is trapped in unfounded 20th century ideas, addiction as a crime or as brain disease, and in equally outdated treatment. Challenging both the idea of the addict's "broken brain" and the notion of a simple "addictive personality," The New York Times Bestseller, Unbroken Brain, offers a radical and groundbreaking new perspective, arguing that addictions are learning disorders and shows how seeing the condition this way can untangle our current debates over treatment, prevention and policy. Like autistic traits, addictive behaviors fall on a spectrum -- and they can be a normal response to an extreme situation. By illustrating what addiction is, and is not, the book illustrates how timing, history, family, peers, culture and chemicals come together to create both illness and recovery- and why there is no "addictive personality" or single treatment that works for all. Combining Maia Szalavitz's personal story with a distillation of more than 25 years of science and research,Unbroken Brain provides a paradigm-shifting approach to thinking about addiction. Her writings on radical addiction therapies have been featured in The Washington Post, Vice Magazine, The Wall Street Journal, and The New York Times, in addition to multiple other publications. She has been interviewed about her book on many radio shows including Fresh Air with Terry Gross and The Brian Lehrer show.