Transition Metal Catalyzed Benzofuran Synthesis Book

Transition Metal Catalyzed Benzofuran Synthesis


  • Author : Xiao-Feng Wu
  • Publisher : Elsevier
  • Release Date : 2017-02-01
  • Genre: Science
  • Pages : 74
  • ISBN 10 : 9780128093702

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Transition Metal Catalyzed Benzofuran Synthesis Excerpt :

Transition Metal-Catalyzed Benzofuran Synthesis: Transition Metal-Catalyzed Heterocycle Synthesis Series provides an overview of benzofuran, describing properties of these heterocycle compounds and the traditional synthetic procedures used for them. The book then explores catalyzed procedures for benzofuran synthesis in greater detail and depth than is currently available in published review articles. This volume is part of the short series authored by Xiao-Feng Wu that summarizes recent achievements on heterocycle synthesis with transition metals as catalysts, with each volume dedicated to one heterocycle compound. Offers a brief, focused review of this active research in benzofuran synthesis via transition metal catalysis Useful coverage of benzofuran properties and both intermolecular and intramolecular cyclization Volume Four in Elsevier’s short work series, Transition Metal-Catalyzed Heterocycles Synthesis Provides greater detail and depth than is currently available in published review articles

Synthesis and Modification of Heterocycles by Metal Catalyzed Cross coupling Reactions Book

Synthesis and Modification of Heterocycles by Metal Catalyzed Cross coupling Reactions


  • Author : Tamás Patonay
  • Publisher : Springer
  • Release Date : 2016-06-15
  • Genre: Science
  • Pages : 362
  • ISBN 10 : 9783319326108

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Synthesis and Modification of Heterocycles by Metal Catalyzed Cross coupling Reactions Excerpt :

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Transition Metal Catalyzed Heterocycle Synthesis via C H Activation Book

Transition Metal Catalyzed Heterocycle Synthesis via C H Activation


  • Author : Xiao-Feng Wu
  • Publisher : John Wiley & Sons
  • Release Date : 2016-03-07
  • Genre: Technology & Engineering
  • Pages : 596
  • ISBN 10 : 9783527338887

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Transition Metal Catalyzed Heterocycle Synthesis via C H Activation Excerpt :

Reflecting the tremendous growth of this hot topic in recent years, this book covers C-H activation with a focus on heterocycle synthesis. As such, the text provides general mechanistic aspects and gives a comprehensive overview of catalytic reactions in the presence of palladium, rhodium, ruthenium, copper, iron, cobalt, and iridium. The chapters are organized according to the transition metal used and sub-divided by type of heterocycle formed to enable quick access to the synthetic route needed. Chapters on carbonylative synthesis of heterocycles and the application of C-H activation methodology to the synthesis of natural products are also included. Written by an outstanding team of authors, this is a valuable reference for researchers in academia and industry working in the field of organic synthesis, catalysis, natural product synthesis, pharmaceutical chemistry, and crop protection.

Catalyzed Carbon Heteroatom Bond Formation Book

Catalyzed Carbon Heteroatom Bond Formation


  • Author : Andrei K. Yudin
  • Publisher : John Wiley & Sons
  • Release Date : 2010-12-01
  • Genre: Science
  • Pages : 522
  • ISBN 10 : 9783527633401

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Catalyzed Carbon Heteroatom Bond Formation Excerpt :

Written by an experienced editor widely acclaimed within the scientific community, this book covers everything from oxygen to nitrogen functionalities. From the contents: * Palladium-Catalyzed Syntheses of Five-Membered Saturated Heterocycles * The Formation of Carbon-Sulfur and Carbon-Selenium Bonds by Substitution and Addition Reactions Catalyzed by Transition Metal Complexes * Palladium-Catalysis for Oxidative 1,2-Difunctionalization of Alkenes * Palladium-Catalyzed Formation of Aromatic Heterocycles * Rhodium-Catalyzed Amination of C-H-Bonds * Transition Metal-Catalyzed Synthesis of Heterocycles * Copper-Catalyzed Synthesis of Azoles * Palladium(II)-Catalyzed C-N Bond Formation Involving Aminopalladation of Aklenes * Carbon-Heteroatom Bond Formation by Rh(I)-Catalyzed Ring-Opening Reactions * Recent Advances in Homogeneous Gold Catalysis: Formation of Carbon-Heteroatom Bonds The result is an indispensable source of information for the strategic planning of the synthetic routes for organic, catalytic and medicinal chemists, as well as chemists in industry.

Modern Heterocyclic Chemistry  4 Volumes Book

Modern Heterocyclic Chemistry 4 Volumes


  • Author : Julio Alvarez-Builla
  • Publisher : John Wiley & Sons
  • Release Date : 2011-08-15
  • Genre: Science
  • Pages : 2531
  • ISBN 10 : 9783527332014

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Modern Heterocyclic Chemistry 4 Volumes Excerpt :

Since vitamins, hormones, antibiotics, pharmaceuticals, dyes and many other products all contain heterocycles, they play an important role in our everyday life. The must-have reference in the field of heterocyclic compounds, comprehensively covering their synthesis, structure and chemical and physical properties in four volumes. It presents a wealth of information but stays userfriendly by focussing on the important facts. An up-to-date source of high-quality information for all organic and medicinal chemists working in this field in industry and academia.

Synthesis of Heterocycles via Metal Catalyzed Reactions that Generate One or More Carbon Heteroatom Bonds Book

Synthesis of Heterocycles via Metal Catalyzed Reactions that Generate One or More Carbon Heteroatom Bonds


  • Author : John P. Wolfe
  • Publisher : Springer
  • Release Date : 2013-09-11
  • Genre: Science
  • Pages : 274
  • ISBN 10 : 9783642388804

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Synthesis of Heterocycles via Metal Catalyzed Reactions that Generate One or More Carbon Heteroatom Bonds Excerpt :

Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Carboamination or Carboalkoxylation Reactions, by John P. Wolfe Synthesis of Saturated Heterocycles via Metal-Catalyzed Alkene Diamination, Aminoalkoxylation, or Dialkoxylation Reactions, by Sherry R. Chemler Synthesis of Heterocycles via Metal-Catalyzed Wacker-Type Oxidative Cyclization Reactions of Alkoxy- or Amino-Alkenes, by Wanbin Zhang Synthesis of Saturated Heterocycles via Metal-Catalyzed Hydroamination or Hydroalkoxylation Reactions, by Lisa D. Julian Synthesis of Saturated Heterocycles via Metal-Catalyzed Allylic Alkylation Reactions, by Aaron Aponick Synthesis of Heterocycles via Metal-Catalyzed Cascade/Domino Reactions that Generate a C–N or C–O Bond, by Mark Lautens Synthesis of Saturated Heterocycles via Metal-Catalyzed Formal Cycloaddition Reactions that Generate a C–N or C–O Bond, by Jerome Waser

Advances in Heterocyclic Chemistry Book

Advances in Heterocyclic Chemistry


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-03-19
  • Genre: Science
  • Pages : 437
  • ISBN 10 : 9780128174746

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Advances in Heterocyclic Chemistry Excerpt :

Advances in Heterocyclic Chemistry, Volume 129 is the definitive series in the field—one of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature also is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive, updated release includes chapters on Metal-Catalyzed Direct Arylation of 1,2-Azoles, The Literature of Heterocyclic Chemistry, Part XVII, 2017, Pyrrolo-, Imidazoquinolines and Pyrroloquinazolines with a Bridgehead Nitrogen, Synthesis and Reactions of Arsole, Stibole, and Bismole, Advances in Synthesis and Chemistry of Aziridines, and more. Considered the definitive serial in the field of heterocyclic chemistry Serves as the go-to reference for organic chemists, polymer chemists and many biological scientists Provides the latest comprehensive reviews written by established authorities in the field Combines descriptive synthetic chemistry and mechanistic insight to enhance understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds

Heterocycles from Double Functionalized Arenes Book

Heterocycles from Double Functionalized Arenes


  • Author : Xiao-Feng Wu
  • Publisher : Royal Society of Chemistry
  • Release Date : 2015-02-02
  • Genre: Science
  • Pages : 301
  • ISBN 10 : 9781782623120

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Heterocycles from Double Functionalized Arenes Excerpt :

The efficient synthesis of heterocycles has become one of the main branches in organic chemistry due to their use in the synthesis of natural products and pharmaceuticals. Current sythentic strategies based on C-H activation methodologies are met with many problems like harsh reaction conditions and low reaction efficiency. Double functionalized chemicals offer a perfect alternative for the synthesis of heterocycles. Heterocycles from Double-Functionalized Arenes starts with a short discussion on the importance of heterocycles and a brief introduction on the preparation of double-functionalized arenes. Specific chapters then look at five-membered heterocycles synthesis, six-membered heterocycles synthesis and macroheterocycles synthesis. This is the first book dedicated to the topic of transition metal catalyzed coupling reactions of double functionalized arenes in heterocycle synthesis and can be used as a handbook for senior researchers and as an introduction for organic chemistry students.

Applications of Transition Metal Catalysis in Drug Discovery and Development Book

Applications of Transition Metal Catalysis in Drug Discovery and Development


  • Author : Matthew L. Crawley
  • Publisher : John Wiley & Sons
  • Release Date : 2012-07-03
  • Genre: Science
  • Pages : 374
  • ISBN 10 : 9780470631324

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Applications of Transition Metal Catalysis in Drug Discovery and Development Excerpt :

This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development – it is a guide, a historical prospective, a practical compendium, and a source of future direction for the field.

Modern Strategies for Heterocycle Synthesis Book

Modern Strategies for Heterocycle Synthesis


  • Author : Gianfranco Favi
  • Publisher : MDPI
  • Release Date : 2021-03-17
  • Genre: Medical
  • Pages : 372
  • ISBN 10 : 9783036503400

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Modern Strategies for Heterocycle Synthesis Excerpt :

Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Transition Metal Catalyzed Furans Synthesis Book

Transition Metal Catalyzed Furans Synthesis


  • Author : Xiao-Feng Wu
  • Publisher : Elsevier
  • Release Date : 2015-09-08
  • Genre: Science
  • Pages : 116
  • ISBN 10 : 9780128040720

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Transition Metal Catalyzed Furans Synthesis Excerpt :

Transition Metal Catalyzed Furans Synthesis provides an overview of Furans, describing properties of these heterocycle compounds and covering traditional synthetic procedures for them. This book then explores catalyzed procedures for Furans synthesis in greater detail and depth then is currently available in published Reviews. Finally, this useful short work discusses natural products and bio-active compounds containing Furans, information of particular interest for their applications to medicinal and pharmaceutical chemistry. The short series Transition Metal Catalyzed Heterocycles Synthesis Series, authored by Xiao-Feng Wu, summarizes recent achievements on heterocycles synthesis with transition metal as the catalysts, with each volume dedicated to one heterocycle compound. Brief, focused review of this active research area, Furans synthesis via transition metal catalysis Useful coverage of furans properties and procedures, as well as relevant Furan-containing natural products First volume in short work series, "Transition Metal-Catalyzed Heterocycles Synthesis"

Organic Syntheses  Volume 96 Book

Organic Syntheses Volume 96


  • Author : John L Wood
  • Publisher : John Wiley & Sons
  • Release Date : 2020-04-14
  • Genre: Science
  • Pages : 648
  • ISBN 10 : 9781119707769

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Organic Syntheses Volume 96 Excerpt :

The current volume continues the tradition of the Organic Syntheses series, providing carefully checked and edited experimental procedures that describe important synthetic methods, transformations, reagents, and synthetic building blocks or intermediates with demonstrated utility in organic synthesis. These significant and interesting procedures should prove worthwhile to many synthetic chemists working in increasingly diverse areas. A trusted guide for professionals in organic and medicinal chemistry in academia, government, and industries, including pharmaceuticals, fine chemicals, agrochemicals, and biotechnological products.

Multicomponent Reactions Book

Multicomponent Reactions


  • Author : K.L. Ameta, Ph.D.
  • Publisher : CRC Press
  • Release Date : 2017-09-20
  • Genre: Medical
  • Pages : 394
  • ISBN 10 : 9781498734196

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Multicomponent Reactions Excerpt :

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.

Organic Reaction Mechanisms 2018 Book

Organic Reaction Mechanisms 2018


  • Author : Mark G. Moloney
  • Publisher : John Wiley & Sons
  • Release Date : 2021-08-17
  • Genre: Science
  • Pages : 688
  • ISBN 10 : 9781119532002

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Organic Reaction Mechanisms 2018 Excerpt :

Organic Reaction Mechanisms 2018, the 54th annual volume in this highly successful and unique series, surveys research on organic reaction mechanisms described in the available literature dated 2018. The following classes of organic reaction mechanisms are comprehensively reviewed: Reaction of Aldehydes and Ketones and their Derivatives Reactions of Carboxylic, Phosphoric, and Sulfonic Acids and their Derivatives Oxidation and Reduction Carbenes and Nitrenes Nucleophilic Aromatic Substitution Electrophilic Aromatic Substitution Carbocations Nucleophilic Aliphatic Substitution Carbanions and Electrophilic Aliphatic Substitution Elimination Reactions Polar Addition Reactions Cycloaddition Reactions Molecular Rearrangements Transition Metal Coupling Radical Reactions An experienced team of authors compile these reviews every year, so that the reader can rely on a continuing quality of selection and presentation.

Heterocyclic Chemistry in Drug Discovery Book
Score: 5
From 1 Ratings

Heterocyclic Chemistry in Drug Discovery


  • Author : Jie Jack Li
  • Publisher : John Wiley & Sons
  • Release Date : 2013-04-26
  • Genre: Science
  • Pages : 720
  • ISBN 10 : 9781118354438

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Heterocyclic Chemistry in Drug Discovery Excerpt :

Enables researchers to fully realize the potential to discover new pharmaceuticals among heterocyclic compounds Integrating heterocyclic chemistry and drug discovery, this innovative text enables readers to understand how and why these two fields go hand in hand in the effective practice of medicinal chemistry. Contributions from international leaders in the field review more than 100 years of findings, explaining their relevance to contemporary drug discovery practice. Moreover, these authors have provided plenty of practical guidance and tips based on their own academic and industrial laboratory experience, helping readers avoid common pitfalls. Heterocyclic Chemistry in Drug Discovery is ideal for readers who want to fully realize the almost limitless potential to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features: Several case studies illustrating the role and application of 3, 4, 5, and 6+ heterocyclic ring systems in drug discovery Step-by-step descriptions of synthetic methods and practical techniques Examination of the physical properties for each heterocycle, including NMR data and quantum calculations Detailed explanations of the complexity and intricacies of reactivity and stability for each class of heterocycles Heterocyclic Chemistry in Drug Discovery is recommended as a textbook for organic and medicinal chemistry courses, particularly those emphasizing heterocyclic chemistry. The text also serves as a guide for medicinal and process chemists in the pharmaceutical industry, offering them new insights and new paths to explore for effective drug discovery.