Type 2 Diabetes and Dementia Book

Type 2 Diabetes and Dementia

  • Author : Velandai Srikanth
  • Publisher : Academic Press
  • Release Date : 2018-02-09
  • Genre: Medical
  • Pages : 320
  • ISBN 10 : 9780128096949

Type 2 Diabetes and Dementia Excerpt :

Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications

Diabetes Mellitus Book

Diabetes Mellitus

  • Author : Yusaku Nakabeppu
  • Publisher : Springer
  • Release Date : 2019-05-06
  • Genre: Medical
  • Pages : 248
  • ISBN 10 : 9789811335402

Diabetes Mellitus Excerpt :

This book describes the precise mechanisms by which insulin resistance and diabetes mellitus (DM) act as risk factors for Alzheimer’s disease (AD). It opens by discussing the de novo synthesis of insulin in the brain and its functional significance with regard to glucose metabolism and maintenance of neuronal function in the brain. The epidemiological evidence that DM is a risk factor for the development of dementia, including AD as well as vascular dementia, is then examined. Subsequent chapters explore in depth the mechanisms involved in this relationship, including abnormal protein processing, dysregulated glucose metabolism, impaired insulin signaling, and mitochondrial dysfunction. The molecular interactions between diabetes and AD are fully discussed, highlighting the pathological molecular mechanisms induced by diabetes that promote and accelerate AD pathology. Finally, diagnostic biomarkers and potential therapeutic approaches for AD are considered on the basis of the presented evidence. In providing answers to the critical questions of whether and why DM is a risk factor for AD, this book will hold appeal for a wide interdisciplinary audience.

Neurodegenerative Diseases Book

Neurodegenerative Diseases

  • Author : Nagehan Ersoy Tunalı
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-01-20
  • Genre: Science
  • Pages : 180
  • ISBN 10 : 9781838801496

Neurodegenerative Diseases Excerpt :

Neurodegenerative diseases represent a very large group of heterogeneous disorders affecting specific subtypes of neurons in the brain. This book contributes insight both to the awareness of the brain and its neurodegenerative states. The chapters present current knowledge regarding genetics, molecular mechanisms, and new therapeutic strategies against neurodegenerative disorders. The book is intended to serve as a source to aid clinicians and researchers in the field, and also life science readers to increase their understanding and awareness of the clinical correlations, genetic aspects, neuropathological findings, and current therapeutic interventions in neurodegenerative diseases. I believe that this book will enlighten the curiosity for neurodegeneration and also encourage researchers to work on potentially effective molecular therapies for still mysterious neurodegenerative disorders.

Neurodegenerative Diseases Book

Neurodegenerative Diseases

  • Author : Shamim I. Ahmad
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-03-12
  • Genre: Medical
  • Pages : 390
  • ISBN 10 : 9781461406532

Neurodegenerative Diseases Excerpt :

The editor of this volume, having research interests in the field of ROS production and the damage to cellular systems, has identified a number of enzymes showing ·OH scavenging activities details of which are anticipated to be published in the near future as confirmatory experiments are awaited. It is hoped that the information presented in this book on NDs will stimulate both expert and novice researchers in the field with excellent overviews of the current status of research and pointers to future research goals. Clinicians, nurses as well as families and caregivers should also benefit from the material presented in handling and treating their specialised cases. Also the insights gained should be valuable for further understanding of the diseases at molecular levels and should lead to development of new biomarkers, novel diagnostic tools and more effective therapeutic drugs to treat the clinical problems raised by these devastating diseases.

The New Threat of Type 3 Diabetes Book

The New Threat of Type 3 Diabetes

  • Author : Alan D. Raguso
  • Publisher : iUniverse
  • Release Date : 2018-11-08
  • Genre: Medical
  • Pages : 130
  • ISBN 10 : 9781532053283

The New Threat of Type 3 Diabetes Excerpt :

The American diet is typically high in sugar consumption and extremely acidic. This lifestyle leads to insulin resistance, inflammation, diabetes, high blood pressure, risk for heart attack or stroke, and possibly dementia and Alzheimer’s disease. In The New Threat of Type 3 Diabetes, authors Alan D. Raguso and Maria Lizotte offer an understanding of diabetes, discussing why people’s health declines and why they get sick. Based on their personal and professional experiences with diabetes, they discuss concepts of body chemistry, look at inflammation as a health risk, and share how it’s a result of improper food intake, heredity, and environmental conditions, along with economics, poor pH balance, lack of moderate exercise, and the modern technological world. Raguso and Lizotte tell how type 3 diabetes is a newly accepted category, connecting a lifetime of damage caused by excessive blood sugar levels. With illustrations and graphics included, The New Threat of Type 3 Diabetes reviews the basic definitions of medical terms, the possible connections to prediabetes, type 2 and type 3 diabetes, and the steps that can be taken to prevent or reverse these diseases. Raguso and Lizotte suggest ways to make simple changes to live more healthily, better, and longer.

Dementia and Chronic Disease Book

Dementia and Chronic Disease

  • Author : Angela Georgia Catic
  • Publisher : Springer Nature
  • Release Date : 2020-06-11
  • Genre: Medical
  • Pages : 241
  • ISBN 10 : 9783030463984

Dementia and Chronic Disease Excerpt :

This book is designed to guide all physicians in long-term care, in-, and outpatient settings who work with elders with co-current dementia and medical comorbidities. Chapters cover a wide range of challenging topics, including epidemiological data, evaluation and management techniques to optimize physical and cognitive function in patients with dementia, safety measures, and nonpharmacologic measures to support cognition. Chapters also discuss the unique aspects of managing the most common chronic diseases and the management of musculoskeletal pain in elders with dementia. Except for the introductory chapter, each chapter will include a case vignette to highlight some of the primary challenges of management of the particular chronic disease/condition in elders with dementia, making this an accessible and highly practical tool for medical professionals of all backgrounds. Written by experts in the field, Dementia and Chronic Disease is an excellent resource for all medical professionals treating patients with dementia, including geriatricians, family medicine physicians, social workers, nurses, hospitalists, and all others.

Depression and Diabetes Book

Depression and Diabetes

  • Author : Wayne Katon
  • Publisher : John Wiley & Sons
  • Release Date : 2011-06-09
  • Genre: Medical
  • Pages : 192
  • ISBN 10 : 9781119957478

Depression and Diabetes Excerpt :

In recent years, there has been a growing awareness of the multiple interrelationships between depression and various physical diseases. The WPA is providing an update of currently available evidence on these interrelationships by the publication of three books, dealing with the comorbidity of depression with diabetes, heart disease and cancer. Depression is a frequent and serious comorbid condition in diabetes, which adversely affects quality of life and the long-term prognosis. Co-occurrent depression presents peculiar clinical challenges, making both conditions harder to manage. Depression and Diabetes is the first book devoted to the interaction between these common disorders. World leaders in diabetes, depression and public health synthesize current evidence, including some previously unpublished data, in a concise, easy-to-read format. They provide an overview of the epidemiology, pathogenesis, medical costs, management, and public health and cultural implications of the comorbidity between depression and diabetes. The book describes how the negative consequences of depression in diabetes could be avoided, given that effective depression treatments for diabetic patients are available. Its practical approach makes the book ideal for all those involved in the management of these patients: psychiatrists, psychologists, diabetologists, general practitioners, diabetes specialist nurses and mental health nurses.

The interaction of type 2 diabetes  type 3 diabetes  Alzheimer s disease   and the gut microbiota Book

The interaction of type 2 diabetes type 3 diabetes Alzheimer s disease and the gut microbiota

  • Author : Hyder Mirghani
  • Publisher : GRIN Verlag
  • Release Date : 2017-12-19
  • Genre: Medical
  • Pages : 57
  • ISBN 10 : 9783668596788

The interaction of type 2 diabetes type 3 diabetes Alzheimer s disease and the gut microbiota Excerpt :

Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, , language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is projected to double by the year 2030 and to triple by 2050. Alzheimer's disease (AD, or type-3 diabetes mellitus) and vascular dementia are the most common forms of dementia. Lifestyle risk factors including obesity and type 2 diabetes increase the risk for the development of both vascular and nonvascular dementia in later life. Previous literature reported that people with diabetes mellitus had 70% greater risk for dementia development.Traditionally, type-2 diabetes and AD (type-3 diabetes) have been thought as independent disorders; recent literature suggests possible links that could lead to common effective modalities of treatment. Furthermore, the highly innervated pancreas shares many features with the brain at molecular levels. Metformin is recommended as the first line for the treatment of patients with type 2 diabetes mellitus due to its effectiveness, favorable effects on lipids and cardiovascular risks, and safety profile.The previous restriction of the use of metformin in patients with the moderate renal disease is loosened by the Food and Drug Organization(5,6). Thus the use of this valuable and affordable drug is expected to increase. The American Diabetes Association recommended the periodic measurement of vitamin B12 and supplementation as needed to reflect the recent evidence showing the association of long-term use of metformin and B12 deficiency.Although the role of vitamin B12 deficiency in the development of dementia is well-established, the role of metformin in B12 deficiency and dementia remain to be elucidated. Insulin resistance is considered as a primary factor for the association of diabetes mellitus a

Endocrinology and Metabolic Diseases Book

Endocrinology and Metabolic Diseases

  • Author : P. N. Plowman
  • Publisher : Elsevier Science & Technology
  • Release Date : 1987
  • Genre: Endocrine glands
  • Pages : 133
  • ISBN 10 : UOM:39015012579796

Endocrinology and Metabolic Diseases Excerpt :

Endocrinology and metabolic diseases are an important area of study in any medical course. This fully indexed text covers the essentials of the subject in a succint and lucid fashion, and several hundred illustrations with numbered labels allow for quick revision.

The Diabetic Brain in Alzheimer s Disease  How Insulin Resistance in Type 2 Diabetes and  Type 3 Diabetes  Triggers Your Risk for Alzheimer s and How Book

The Diabetic Brain in Alzheimer s Disease How Insulin Resistance in Type 2 Diabetes and Type 3 Diabetes Triggers Your Risk for Alzheimer s and How

  • Author : Ralph Sanchez Mtcm
  • Publisher : Braindefend LLC
  • Release Date : 2019-08-21
  • Genre: Medical
  • Pages : 122
  • ISBN 10 : 1732668701

The Diabetic Brain in Alzheimer s Disease How Insulin Resistance in Type 2 Diabetes and Type 3 Diabetes Triggers Your Risk for Alzheimer s and How Excerpt :

The thought of living out one's life with dementia conjures up a helpless and foreboding feeling. What if it happens to me?Can I do anything to prevent it?One in ten people age 65 and older has Alzheimer's, and the prevalence of the disease jumps to three in ten after the age of 85. One in three seniors will die from Alzheimer's or another form of dementia according to the Alzheimer's Association. The financial burden for top level care can be staggering, and the difficult challenges imposed by attending to care and finances can be extremely stressful and exhausting for family as well as caretakers.Is there an answer for you and the Alzheimer's pandemic that is projected to almost triple by the year 2050? To date, drug trials are struggling to provide any meaningful interventions, and it is unlikely that a pharmaceutical centered approach will provide anything resembling a cure or a reversal of the disease process anytime soon. There is hope! The solution is based on early detection and intervention. Scientific research as well as many enlightened physicians and clinics are now demonstrating that prevention is possible, and the key lies in a comprehensive evaluation of your risk for Alzheimer's long before the onset of dementia. This is vital as we now know that the Alzheimer's disease process starts decades before you might notice you are in trouble.Don't wait to be diagnosed! The Diabetic Brain in Alzheimer's Disease reveals the most critical and common risk factors for Alzheimer's disease as you age, and how you can take control of your risk. The in-depth science-based information in this book will illuminate your path to protecting your brain and drastically reducing your odds of developing Alzheimer's as you age. Read this book and discover the actionable steps that you can begin taking now to save your brain from dementia.

Memory Loss  Alzheimer s Disease  and Dementia E Book Book

Memory Loss Alzheimer s Disease and Dementia E Book

  • Author : Andrew E. Budson
  • Publisher : Elsevier Health Sciences
  • Release Date : 2015-05-20
  • Genre: Medical
  • Pages : 276
  • ISBN 10 : 9780323316101

Memory Loss Alzheimer s Disease and Dementia E Book Excerpt :

Now presented in full color, this updated edition of Memory Loss, Alzheimer's Disease, and Dementia is designed as a practical guide for clinicians that delivers the latest treatment approaches and research findings for dementia and related illnesses. Drs. Budson and Solomon — both key leaders in the field — cover the essentials of physical and cognitive examinations and laboratory and imaging studies, giving you the tools you need to consistently make accurate diagnoses in this rapidly growing area. Access in-depth coverage of clinically useful diagnostic tests and the latest treatment approaches. Detailed case studies facilitate the management of both common and uncommon conditions. Comprehensive coverage of hot topics such as chronic traumatic encephalopathy, in addition to new criteria on vascular dementia and vascular cognitive impairment. Includes new National Institute on Aging–Alzheimer's Association and DSM-5 criteria for Alzheimer’s Disease and Mild Cognitive Impairment. Learn how to use new diagnostic tests, such as the amyloid imaging scans florbetapir (Amyvid), flutemetamol (Vizamyl), and florbetaben (Neuraceq), which can display amyloid plaques in the living brains of patients. Updated case studies, many complete with videos illustrating common tests, clinical signs, and diagnostic features, are now incorporated into the main text as clinical vignettes for all major disorders. Brand-new chapters on how to approach the differential diagnosis and on primary progressive aphasia. Medicine eBook is accessible on a variety of devices.

Type 2 Diabetes Book

Type 2 Diabetes

  • Author : Mira Siderova
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-11-27
  • Genre: Medical
  • Pages : 166
  • ISBN 10 : 9781789239713

Type 2 Diabetes Excerpt :

The emergence of type 2 diabetes as a global pandemic is one of the major challenges to health care in the 21st century. This book contains chapters covering the newest scientific concepts in the pathogenesis of type 2 diabetes, and the complications and approaches in diagnosis and glycemic control. Part of the book is dedicated to the effect of diabetes on the mental functions and treatment strategies to prevent cognitive decline. Glucose monitoring, using cutting-edge technologies, is outlined, as well as the role of health information technologies in diabetes management. Updates on glucose lowering therapy are presented, and the new emerging class of SGLT2 inhibitors is discussed in detail. The purpose of this book is to disseminate knowledge on type 2 diabetes and to contribute to the professional development of physicians, internists, endocrinologists, medical students, and research scientists in diabetes.

Diabetic Retinopathy and Cardiovascular Disease Book

Diabetic Retinopathy and Cardiovascular Disease

  • Author : C. Sabanayagam
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2019-06-03
  • Genre: Medical
  • Pages : 134
  • ISBN 10 : 9783318065077

Diabetic Retinopathy and Cardiovascular Disease Excerpt :

Diabetic retinopathy (DR), a common microvascular complication, has consistently been shown to be associated with an increased risk of cardiovascular disease (CVD). This book provides complete coverage of DR as a potential marker for CVD in those with diabetes. It succinctly reviews the epidemiological and pathogenic links of DR to various cardiovascular events including stroke, coronary artery disease, chronic kidney disease, heart failure, and mortality. Furthermore, it discusses the usefulness of DR in CVD risk prediction and cardiovascular safety of anti-VEGF therapy in diabetic patients. There are insights from contemporary diabetic trials that demonstrated the enhanced cardiovascular benefit of novel glucose lowering therapy. It also highlights the potential of novel retinal imaging to predict CVD and its risk factors using the state-of-the art artificial intelligence-based deep learning systems. This book will be an invaluable resource for specialists translating research findings into clinical care, including those in cardiology, endocrinology, ophthalmology, and general practitioners. IT will also be of interest to public health practitioners, researchers, graduate students, and biotech companies interested in developing retinal image-based diagnostic and prognostic tools.

Increase Your Brainability  And Reduce Your Risk of Dementia Book

Increase Your Brainability And Reduce Your Risk of Dementia

  • Author : Charles Alessi
  • Publisher : Oxford University Press
  • Release Date : 2021
  • Genre: Dementia
  • Pages : 177
  • ISBN 10 : 9780198860341

Increase Your Brainability And Reduce Your Risk of Dementia Excerpt :

Dreaded by many people as an inevitable part of normal aging, Dementia has displaced Cancer as the most feared health problem. Cancer continues to be a serious condition, but it is often curable, and almost always treatable. In contrast, the fear of dementia is complicated by the fear of ageing, and by muddled thinking about its relationship with Alzheimer's disease. Yet, there is no reason to be disheartened. Ever-evolving scientific evidence means that we can be increasingly optimistic about the future, and on-going research shows that the problems we dread- dementia, disability and dependency- can be controlled. By taking steps to limit damage to the brain caused by stress, sleep problems, and inactivity throughout our lives, it is more than possible to substantially reduce your risk of dementia. Equally, a loss of physical fitness (which starts long before old age) is preventable. Based on research from the Optimal Ageing Programme, and full of practical, evidence-based advice on managing the major risk factors underpinning dementia, this book will inspire readers to fight back against the modern environment and negative societal attitudes. Through simple but effective lifestyle changes that anyone can make, everyone can take positive action to increase their brainability. It is never too late to change your life, reduce your risk, and live better for longer.