Unraveling the Complexities of Metastasis Book

Unraveling the Complexities of Metastasis

  • Author : Ammad Ahmad Farooqi
  • Publisher : Academic Press
  • Release Date : 2022-05-27
  • Genre: Science
  • Pages : 342
  • ISBN 10 : 9780128217900

Unraveling the Complexities of Metastasis Excerpt :

Unraveling the Complexities of Metastasis: Transition from a Segmented View to a Conceptual Continuum provides a critical overview of the recent developments of metastasis research and how progress can be further enhanced in the field. Metastasis is a highly complicated mechanism and prognostic analysis of different metastatic patterns in advanced cancer patients is becoming increasingly problematic. It is therefore essential to take a step back and focus on the underlying mechanisms of metastasis before moving ahead for effective translation of laboratory findings to clinically effective therapeutics. This book is surely helpful in putting together missing pieces of an incomplete jig-saw puzzle of molecular cancer. The book discusses topics such as the role of TRAIL-mediated signaling, late metastasis and mechanisms underlying tumor cell dormancy, CTCs and exomes, non-coding way of metastasis, and stem cells. Additionally, it brings relevant and updated information on nanotechnology-based docetaxel and the peculiarities of cancer cell metabolism. This book is a valuable source for cancer researchers, medical doctors and several members of biomedical field who need to understand better the complex mechanism of metastasis. Explains the mechanism of metastasis from basic to advanced level through easy and comprehensive chapters written by internationally distinguished researchers Provides simplified version of important process of metastasis for the readers to comprehend the latest advancements made in the field Presents colorful diagrams to make different aspects of scientifically difficult topics easier for young researchers and newcomers in the field of cancer metastasis

Molecular and Cellular Basis of Metastasis  Road to Therapy Book

Molecular and Cellular Basis of Metastasis Road to Therapy

  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2016-09-03
  • Genre: Medical
  • Pages : 390
  • ISBN 10 : 9780128041581

Molecular and Cellular Basis of Metastasis Road to Therapy Excerpt :

Molecular and Cellular Basis of Metastasis: Road to Therapy, the latest in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, with this volume covering the molecular and cellular basis of metastasis. Presents groundbreaking information on the molecular and cellular basis of metastasis Provides information on cancer research Outstanding and original reviews Suitable for both researchers and students

Oncogene and Cancer Book

Oncogene and Cancer

  • Author : Yahwardiah Siregar
  • Publisher : Inst za onkologiju i radiol
  • Release Date : 2013-01-24
  • Genre: Medical
  • Pages : 498
  • ISBN 10 : 9789535108580

Oncogene and Cancer Excerpt :

This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors

Hsp90 in Cancer  Beyond the Usual Suspects Book

Hsp90 in Cancer Beyond the Usual Suspects

  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2016-02-23
  • Genre: Science
  • Pages : 288
  • ISBN 10 : 9780128024836

Hsp90 in Cancer Beyond the Usual Suspects Excerpt :

Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression. Focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins Highlights the rapidly evolving understanding of the fundamental roles of Hsp90 in cancer biology Discusses the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression

Metastatic Progression and Tumour Heterogeneity Book

Metastatic Progression and Tumour Heterogeneity

  • Author : Fred Hollande
  • Publisher : MDPI
  • Release Date : 2021-01-21
  • Genre: Science
  • Pages : 312
  • ISBN 10 : 9783039288533

Metastatic Progression and Tumour Heterogeneity Excerpt :

Improved understanding of the cellular and molecular makeup of tumors in the last 30 years has unraveled a previously unexpected level of heterogeneity among tumor cells as well as within the tumor microenvironment. The concept of tumor heterogeneity underlines the realization that different tumors can display significant differences in their genomic content as well as in their overall behavior. Our capacity to better understand the heterogeneous make up of tumors has very important consequences on our ability to design efficient therapeutic strategies to improve patient survival. This book highlights several aspects of tumor heterogeneity in the context of metastatic development and summarize some of the challenges posed by heterogeneity for tumor diagnostics and therapeutic management of tumors.

Your Cannabis CBD THC Ratio Book

Your Cannabis CBD THC Ratio

  • Author : Uwe Blesching
  • Publisher : Ed Rosenthal
  • Release Date : 2020-12-15
  • Genre: Medical
  • Pages : 240
  • ISBN 10 : 9781936807536

Your Cannabis CBD THC Ratio Excerpt :

The author of the game-changing Cannabis Health Index returns with a book designed specifically for general readers who want to understand how THC and CBD can benefit them. While CBD is the new buzzword for health and wellness, many researchers and practitioners believe that the symbiotic relationship between THC and CBD, known as the entourage effect, allows for greater therapeutic benefits for patients. Unfortunately, when it comes to optimizing that ratio to a particular health condition, it is often a process of trial and error for medical patients. Your Cannabis CBD:THC Ratio provides detailed information on how to find the best ratios of CBD:THC and covers the preferred ratios of these two primary cannabinoids for ten prevalent medical conditions —including cancer, chronic pain, anxiety, insomnia, and many others. Blesching’s unique chemotype-based system takes into account CBD:THC ratios, the various forms of cannabis medicine available to consumers, and the subjective therapeutic dosages, presenting a complete evidence-based methodology. -- Uwe Blesching, PH.D.

Cannabis as Medicine Book

Cannabis as Medicine

  • Author : Betty Wedman-St.Louis
  • Publisher : CRC Press
  • Release Date : 2019-09-26
  • Genre: Medical
  • Pages : 312
  • ISBN 10 : 9780429622199

Cannabis as Medicine Excerpt :

For hundreds of years cannabis has been used as a therapeutic medicine around the world. Cannabis was an accepted medicine during the second half of the 19th century, but its use declined because single agent pain medications were advocated by physicians who demanded standardization of medicines. It was not until 1964 when the chemical structure of THC (delta 9-tetrahydrocannabinol) was elucidated and its pharmacological effects began to be understood. Numerous therapeutic effects of cannabis have been reviewed, but cannabis-based medicines are still an enigma because of legal issues. Many patients could benefit from cannabinoids, terpenoids and flavonoids found in Cannabis sativa L. These patients suffer from medical conditions including chronic pain, chronic inflammatory diseases, neurological disorders, and other debilitating illnesses. As more states are legalizing medical cannabis, prescribers need a reliable source which provides clinical information in a succinct format. This book focuses on the science of cannabis as an antioxidant and anti-inflammatory supplement. It discusses cannabis uses in the human body for bone health/osteoporosis; brain injury and trauma; cancer; diabetes; gastrointestinal conditions; mental health disorders; insomnia; pain; anxiety disorders; depression; migraines; eye disorders; and arthritis and inflammation. There is emphasis on using the whole plant — from root to raw leaves and flowers discussing strains, extraction and analysis, and use of cannabis-infused edibles. Features: Provides an understanding of the botanical and biochemistry behind cannabis as well as its use as a dietary supplement. Discusses endocannabinoid system and cannabinoid receptors. Includes information on antioxidant benefits, pain receptors using cannabinoids, and dosage guidelines. Presents research on cannabis treatment plans, drug-cannabis interactions and dosing issues, cannabis vapes, edibles, creams, and suppositories. Multiple appendices including

Holland Frei Cancer Medicine Book

Holland Frei Cancer Medicine

  • Author : Robert C. Bast, Jr.
  • Publisher : John Wiley & Sons
  • Release Date : 2017-03-10
  • Genre: Medical
  • Pages : 2008
  • ISBN 10 : 9781119000846

Holland Frei Cancer Medicine Excerpt :

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Immunotherapy for Solid Malignancies  An Issue of Surgical Oncology Clinics of North America Book

Immunotherapy for Solid Malignancies An Issue of Surgical Oncology Clinics of North America

  • Author : Alfred E. Chang
  • Publisher : Elsevier Health Sciences
  • Release Date : 2019-05-11
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 9780323678261

Immunotherapy for Solid Malignancies An Issue of Surgical Oncology Clinics of North America Excerpt :

This issue of Surgical Oncology Clinics of North America focuses on Immunotherapy for Solid Malignancies and is edited by Dr. Alfred E. Chang. Articles will include: Current immunotherapy practices for melanoma; Immunotherapy for ovarian cancer; Vaccines therapies for melanoma; Vaccine therapies for breast cancer; Induced pleuripotent T cells for adoptive immunotherapy; Future research goals in immunotherapy; Oncolytic immunotherapy; Adoptive T cell therapy for solid malignancies; Checkpoint inhibition immunotherapy; Toxicities of immunotherapy agents; Immunologic targeting of cancer stem cells; Role of surgery in combination with immunotherapy; and more!

Ecology and Evolution of Poeciliid Fishes Book

Ecology and Evolution of Poeciliid Fishes

  • Author : Jonathan P. Evans
  • Publisher : University of Chicago Press
  • Release Date : 2011-09-26
  • Genre: Science
  • Pages : 424
  • ISBN 10 : 9780226222769

Ecology and Evolution of Poeciliid Fishes Excerpt :

The history of biology is populated by numerous model species or organisms. But few vertebrate groups have aided evolutionary and ecological research more than the live-bearing fishes of the family Poeciliidae. Found throughout tropical and subtropical waters, poeciliids exhibit a fascinating variety of reproductive specializations, including viviparity, matrotrophy, unisexual reproduction, and alternative mating strategies, making them ideal models for research on patterns and processes in ecology, behavior, and evolution. Ecology and Evolution of Poeciliid Fishes is a much-needed overview of the scientific potential and understanding of these live-bearing fishes. Chapters by leading researchers take up a wide range of topics, including the evolution of unisexual reproduction, life in extreme environments, life-history evolution, and genetics. Designed to provide a single and highly approachable reference, Ecology and Evolution of Poeciliid Fishes will appeal to students and specialists interested in all aspects of evolutionary ecology.

Recent Advances in Cancer Research and Therapy Book

Recent Advances in Cancer Research and Therapy

  • Author : Xin-Yuan Liu
  • Publisher : Elsevier
  • Release Date : 2012
  • Pages : 674
  • ISBN 10 : 9780123978332

Recent Advances in Cancer Research and Therapy Excerpt :

Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super Interferon, HecI based and liposome based therapy, gene therapy, and p53 based cancer therapy. There is also a discussion of current cancer research in China including traditional Chinese medicine. Written by leading scientists in the field, this book provides an essential insight into the current state of cancer therapy and treatment. Includes a wide range of research areas including a focus on biotherapy and the development of novel cancer therapeutic strategies. Formatted for a broad audience including all working in researching cancer treatments and therapies. Discusses special traits and results of Chinese cancer research.

Metastasis Book


  • Author : Lalage Wakefield
  • Publisher : IOS Press
  • Release Date : 2007
  • Genre: Medical
  • Pages : 162
  • ISBN 10 : 1586037536

Metastasis Excerpt :

"Metastasis is the most dreaded aspect of the carcinogenic process. More than ninety percent of all cancer deaths are attributable to the consequences of the primary tumor successfully colonizing distant organs. Unlike the situation with colon cancer, a patient with breast cancer can never be considered cured, since as many as a third of breast cancer patients who have apparently curative surgery for their primary tumors ultimately relapse with metastatic disease, sometimes decades later. Much effort is now devoted to understanding this process of metastasis, and finding ways to predict and prevent its occurrence. This publication covers recent advances in the field, specifically as they relate to breast cancer. The availability of new tools and technological approaches has prompted a reconsideration of the very definition of a metastasis. Furthermore, a number of commonly held myths are being explored and a new definition of a metastasis, with important implications for clinical staging, is being proposed. Also, a novel conceptual framework for cancer progression based on the system-level dynamics of regulatory networks is presented and the role of chemokines in mediating some of the evolving transactional processes between tumor and stroma is being reviewed."

Cancer Research Book

Cancer Research

  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2006-04
  • Genre: Cancer
  • Pages : null
  • ISBN 10 : CORNELL:31924101052227

Cancer Research Excerpt :

Biomaterials for 3D Tumor Modeling Book

Biomaterials for 3D Tumor Modeling

  • Author : Subhas C. Kundu
  • Publisher : Elsevier
  • Release Date : 2020-08-22
  • Genre: Technology & Engineering
  • Pages : 772
  • ISBN 10 : 9780128181294

Biomaterials for 3D Tumor Modeling Excerpt :

Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine. Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery